Citation Impact
Citing Papers
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
2001 StandoutScienceNobel
A Conserved Family of Prolyl-4-Hydroxylases That Modify HIF
2001 StandoutScience
The Crystal Structure of the Ribosome Bound to EF-Tu and Aminoacyl-tRNA
2009 StandoutScienceNobel
Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1
1996 StandoutNobel
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
2011 StandoutNobel
The Drosophila melanogaster similar bHLH-PAS gene encodes a protein related to human hypoxia-inducible factor 1α and Drosophila single-minded
1996
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Proteins regulating Ras and its relatives
1993 StandoutNature
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
2001 StandoutNobel
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
1998 StandoutNature
Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL
2002 StandoutNatureNobel
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
Computational identification of the Spo0A-phosphate regulon that is essential for the cellular differentiation and development in Gram-positive spore-forming bacteria
2003
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
1999 StandoutNatureNobel
Cascade regulation of nif gene expression in Rhizobium meliloti
1988
HIF-1, O2, and the 3 PHDs
2001 StandoutNobel
The GTPase superfamily: conserved structure and molecular mechanism
1991 StandoutNature
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
1994 StandoutScienceNobel
The Spo0A Protein of Bacillus subtilis Inhibits Transcription of the abrB Gene without Preventing Binding of the Polymerase to the Promoter
1996
Mutational dissociation of the positive and negative regulatory properties of the SpoOA sporulation transcription factor of Bacillus subtilis
1991
The Spo0A regulon of Bacillus subtilis
2003
A Role for Asp75 in Domain Interactions in theBacillus subtilis Response Regulator Spo0A
2000
Phosphorylation of Spo0A activates its stimulation of in vitro transcription from the Bacillus subtilis spollG operon
1993
DNA Complexed Structure of the Key Transcription Factor Initiating Development in Sporulating Bacteria
2002
Mechanisms of angiogenesis
1997 StandoutNature
Emergence of vancomycin tolerance in Streptococcus pneumoniae
1999 StandoutNatureNobel
HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells
2007 StandoutNobel
Membrane‐associated GTPases in bacteria
1992
COMMUNICATION MODULES IN BACTERIAL SIGNALING PROTEINS
1992
SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER
1993 StandoutNatureNobel
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Perspectives on Oxygen Sensing
1999 StandoutNobel
REGULATION OF THE PHOSPHORELAY AND THE INITIATION OF SPORULATION IN BACILLUS SUBTILIS
1993
GENETIC NETWORKS CONTROLLING THE INITIATION OF SPORULATION AND THE DEVELOPMENT OF GENETIC COMPETENCE IN BACILLUS SUBTILIS
1995
Kinase–phosphatase competition regulates Bacillus subtilis development
1998
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
Digoxin inhibits development of hypoxic pulmonary hypertension in mice
2012 StandoutNobel
The structure of LepA, the ribosomal back translocase
2008 StandoutNobel
Biochemistry of Nitric Oxide and Its Redox-Activated Forms
1992 StandoutScience
Identification of a Second Region of the Spo0A Response Regulator of Bacillus subtilis Required for Transcription Activation
2000
A Region in the Bacillus subtilis Transcription Factor Spo0A That Is Important for spoIIG Promoter Activation
1998
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.
1993 StandoutNobel
Identification of Two GTP-Binding Proteins in the Chloroplast Protein Import Machinery
1994 StandoutScienceNobel
Hypoxia-inducible factor 1α protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations
2000 StandoutNobel
Physiology meets biophysics: Visualizing the interaction of hypoxia-inducible factor 1α with p300 and CBP
2002 StandoutNobel
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
1995 StandoutNobel
Mechanism of GTP hydrolysis by G-protein alpha subunits.
1994 StandoutNobel
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
2011 StandoutNobel
Decoupling function and taxonomy in the global ocean microbiome
2016 StandoutScience
Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide.
1993
Predicting Coiled Coils from Protein Sequences
1991 StandoutScience
Requirement for a GTPase-Activating Protein in Vesicle Budding from the Endoplasmic Reticulum
1993 StandoutScienceNobel
PAS Domains: Internal Sensors of Oxygen, Redox Potential, and Light
1999
Protein phosphorylation and regulation of adaptive responses in bacteria
1989
An A257V Mutation in the Bacillus subtilis Response Regulator Spo0A Prevents Regulated Expression of Promoters with Low-Consensus Binding Sites
2009 StandoutNobel
The SpoOA protein of Bacillus subtilis is a repressor of the abrB gene.
1990
Spo0A Mutants of Bacillus subtilis with Sigma Factor-Specific Defects in Transcription Activation
1998
Bacterial community assembly based on functional genes rather than species
2011
Spo0A binds to a promoter used by sigma A RNA polymerase during sporulation in Bacillus subtilis.
1991
Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1α-deficient chimeric mice
2002 StandoutNobel
Soj Antagonizes Spo0A Activation of Transcription in Bacillus subtilis
2005
The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans
1995 StandoutNobel
Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth
1997 StandoutNobel
Evolution of a molecular switch: universal bacterial GTPases regulate ribosome function
2001
Nitric oxide-induced S-nitrosylation of glyceraldehyde-3-phosphate dehydrogenase inhibits enzymatic activity and increases endogenous ADP-ribosylation.
1992
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
MOLECULAR GENETICS OF SPORULATION IN BACILLUS SUBTILIS
1996
Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
2009 StandoutNobel
Pathways for Oxygen Regulation and Homeostasis
2016 StandoutNobel
Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice
2009 StandoutNobel
Nitric oxide prevents axonal degeneration by inducing HIF-1–dependent expression of erythropoietin
2011 StandoutNobel
trachealess encodes a bHLH-PAS protein that is an inducer of tracheal cell fates in Drosophila.
1996
Phosphorylation of Bacillus subtilis transcription factor Spo0A stimulates transcription from the spoIIG promoter by enhancing binding to weak 0A boxes
1994
Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-kappa B.
1996 StandoutNobel
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
Surfaces of Spo0A and RNA Polymerase Sigma Factor A That Interact at the spoIIG Promoter in Bacillus subtilis
2003
Diversity of G Proteins in Signal Transduction
1991 StandoutScience
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
DNA strand separation during activation of a developmental promoter by the Bacillus subtilis response regulator Spo0A
1998
The trans‐activation domain of the sporulation response regulator Spo0A revealed by X‐ray crystallography
2000
Works of K Trach being referenced
Control of the initiation of sporulation in Bacillus subtilis by a phosphorelay
1991
SpoOA activates and represses its own synthesis by binding at its dual promoters
1992
Structural alterations in the Bacillus subtilis Spo0A regulatory protein which suppress mutations at several spo0 loci
1990
Sequence analysis of the spo0B locus reveals a polycistronic transcription unit
1985
Identification of the transcriptional suppressor sof-1 as an alteration in the spo0A protein
1985
Complete sequence and transcriptional analysis of the spo0F region of the Bacillus subtilis chromosome
1988
The Bacillus subtilis spo0B stage 0 sporulation operon encodes an essential GTP-binding protein
1989
Biochemical characterization of the essential GTP-binding protein Obg of Bacillus subtilis
1994
Effects on Bacillus subtilis of a conditional lethal mutation in the essential GTP-binding protein Obg
1994
Identification of the 37-kDa protein displaying a variable interaction with the erythroid cell membrane as glyceraldehyde-3-phosphate dehydrogenase.
1987
Deduced product of the stage 0 sporulation gene spo0F shares homology with the Spo0A, OmpR, and SfrA proteins.
1985
Characterization of the gene for a protein kinase which phosphorylates the sporulation-regulatory proteins Spo0A and Spo0F of Bacillus subtilis
1989
Characterization of the spo0A locus and its deduced product.
1985