Citation Impact
Citing Papers
Disruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice
2011 StandoutNobel
PD-1-Mediated Suppression of IL-2 Production Induces CD8+ T Cell Anergy In Vivo
2009 StandoutNobel
Neutralization of IFNγ defeats haemophagocytosis in LCMV‐infected perforin‐ and Rab27a‐deficient mice
2009
Impaired immune and acute-phase responses in interleukin-6-deficient mice
1994 StandoutNatureNobel
Interleukin-6 in Biology and Medicine
1993
The paradigm of IL-6: from basic science to medicine.
2002
Transplant Tolerance in Non-Human Primates: Progress, Current Challenges and Unmet Needs
2006
Molecular Events Mediating T Cell Activation
1990
T‐cell response relative to genotype and ethnicity during antiviral therapy for chronic hepatitis C†
2005
Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo
2002 Standout
Cytokine Pathways and Joint Inflammation in Rheumatoid Arthritis
2001 Standout
Role of the CTLA-4 receptor in t cell activation and immunity
1998
Association of Fibrinogen, C-reactive Protein, Albumin, or Leukocyte Count With Coronary Heart Disease
1998 Standout
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
Lymphocyte responses and cytokines
1994 Standout
T Cell–Mediated Elimination of B7.2 Transgenic B Cells
1997 StandoutNobel
Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study
2008 Standout
Interleukin-6 in clinical medicine
1991
Recombinant Human Single Chain Fv Antibodies Recognizing Human Interleukin-6
1998 StandoutNobel
Preferential replication of HIV-1 in the CD45RO memory cell subset of primary CD4 lymphocytes in vitro.
1997
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
2004 StandoutNobel
The Role of CD28 Costimulation in the Generation of Cytotoxic T Lymphocytes
1995
The B7 and CD28 receptor families
1994
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Interleukin-6: An Overview
1990 Standout
In vivoblockade of CTLA-4 enhances the priming of responsive T cells but fails to prevent the induction of tumor antigen-specific tolerance
1999 StandoutNobel
Costimulation via Glucocorticoid-Induced TNF Receptor in Both Conventional and CD25+ Regulatory CD4+ T Cells
2004 StandoutNobel
Interleukin-6 is not involved in the interleukin-1-induced production of colony-stimulating factors by human bone marrow stromal cells and fibroblasts
1989
Interleukin 7 is a T-cell growth factor.
1989
Flying Under the Radar: The Immunobiology of Hepatitis C
2006 StandoutNobel
Expression of murine interleukin 7 in a murine glioma cell line results in reduced tumorigenicity in vivo.
1992 StandoutNobel
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages
1999 StandoutNobel
CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells.
1996 StandoutNobel
Interleukin-6 and the acute phase response
1990 Standout
Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4
2000 StandoutNobel
Phenotypic Analysis of Antigen-Specific T Lymphocytes
1996 StandoutScience
CTLA-4 Is Not Required for Induction of CD8+ T Cell Anergy In Vivo
2001
IL-6 enhances the generation of cytolytic T lymphocytes in the allogeneic mixed leucocyte reaction
1992 StandoutNobel
The AP1-dependent secretion of galectin-1 by Reed–Sternberg cells fosters immune privilege in classical Hodgkin lymphoma
2007 Standout
Interaction of CTLA-4 with AP50, a clathrin-coated pit adaptor protein
1997 StandoutNobel
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation.
1995 StandoutNobel
Preferential Localization of Effector Memory Cells in Nonlymphoid Tissue
2001 StandoutScience
Interleukin-1 induces interleukin-6 production in peripheral blood monocytes
1990
CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma.
1996 Standout
Activation of cytokine genes in T cells during primary and secondary murine influenza pneumonia.
1993 StandoutNobel
Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice.
1993
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Cytokine Storm
2020 Standout
Immunosuppressive regulatory T cells are abundant in the reactive lymphocytes of Hodgkin lymphoma
2003
Interleukin 6: A Multifunctional Cytokine Regulating Immune Reactions and the Acute Phase Protein Response
1990
Induction of T Cell Anergy in the Absence of CTLA-4/B7 Interaction
2000
Chimeric Antigen Receptor Therapy
2018 Standout
The Yin and Yang of T Cell Costimulation
1995 StandoutScienceNobel
Pivotal role of the B7:CD28 pathway in transplantation tolerance and tumor immunity
1994
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
1993 StandoutScience
Importance of IL-10 for CTLA-4-Mediated Inhibition of Tumor-Eradicating Immunity
2004
Plasma Concentration of Interleukin-6 and the Risk of Future Myocardial Infarction Among Apparently Healthy Men
2000 Standout
CTLA-4-Mediated Inhibition in Regulation of T Cell Responses: Mechanisms and Manipulation in Tumor Immunotherapy
2001 StandoutNobel
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
2004 StandoutNobel
Itk Negatively Regulates Induction of T Cell Proliferation by CD28 Costimulation
1997 StandoutNobel
Recovery of Replication-Competent HIV Despite Prolonged Suppression of Plasma Viremia
1997 StandoutScience
The Role of B7 Costimulation in CD4/CD8 T Cell Homeostasis
2000 StandoutNobel
Enhancement of Antitumor Immunity by CTLA-4 Blockade
1996 StandoutScienceNobel
Thymus and Autoimmunity: Production of CD25+CD4+ Naturally Anergic and Suppressive T Cells as a Key Function of the Thymus in Maintaining Immunologic Self-Tolerance
1999 StandoutNobel
Visualization, characterization, and turnover of CD8+ memory T cells in virus-infected hosts.
1996
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
Antigen-dependent CD28 Signaling Selectively Enhances Survival and Proliferation in Genetically Modified Activated Human Primary T Lymphocytes
1998
Endogenously Expressed nef Uncouples Cytokine and Chemokine Production from Membrane Phenotypic Maturation in Dendritic Cells
2002 StandoutNobel
Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.
1991 Standout
PD-1 and Its Ligands in Tolerance and Immunity
2008 Standout
The Continuing Challenges of Leprosy
2006 Standout
Thrombocytosis in patients with tumors producing colony-stimulating factor
1992 StandoutNobel
B7 Expression on T Cells Down-Regulates Immune Responses through CTLA-4 Ligation via R-T Interactions
2004 StandoutNobel
Works of K Lorré being referenced
Evaluation of B7-1 (CD80) and B7-2 (CD86) Costimulatory Molecules and Dendritic Cells on the Immune Response in Leprosy.
2001
Delayed neutralization of interferon-γ prevents lethality in primate Gram-negative bacteremic shock
2005
Interleukin-1 and B7/CD28 Interaction Regulate Interleukin-6 Production by Human T Cells
1994
The anti-T cell monoclonal antibody 9.3 (Anti-CD28) provides a helper signal and bypasses the need for accessory cells in T Cell activation with immobilized anti-CD3 and mitogens
1989
A bidirectional regulatory network involving IL 2 and IL 4 in the alternative CD2 pathway of T cell activation
1990
Prolonged Skin Graft Survival by Administration of Anti-CD8C Monoclonal Antibody with Cyclosporin A
1999
Human T cell activation with phytohemagglutinin. The function of IL-6 as an accessory signal.
1988
Blocking of costimulation prevents kidney graft rejection in rhesus monkeys
1998
Human CTLA-4 is expressed in situ on T lymphocytes in germinal centers, in cutaneous graft-versus-host disease, and in Hodgkin's disease.
1998
CD45RO+ memory T cells but not CD45RA+ naive T cells can be efficiently activated by remote co-stimulation with B7
1993
IL-6 is an accessory signal in the alternative CD2-mediated pathway of T cell activation.
1990
B7-blocking agents, alone or in combination with cyclosporin A, induce antigen-specific anergy of human memory T cells.
1997