Standout Papers

Induced pluripotent stem cell–derived hepatocytes have the functional and proliferative capabilit... 2010 2026 2015 2020 134
  1. Induced pluripotent stem cell–derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice (2010)
    Silvia Espejel, Garrett R. Roll et al. Journal of Clinical Investigation

Citation Impact

Citing Papers

Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells
2008 StandoutScienceNobel
Epigenetic memory of active gene transcription is inherited through somatic cell nuclear transfer
2005 StandoutNobel
Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons
2020 StandoutNobel
Podocin and MEC-2 bind cholesterol to regulate the activity of associated ion channels
2006 StandoutNobel
Transposition-Driven Genomic Heterogeneity in the Drosophila Brain
2013 StandoutScienceNobel
Mash2 Acts Cell Autonomously in Mouse Spongiotrophoblast Development
1997
β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin
2001 Standout
MiRP1 Forms IKr Potassium Channels with HERG and Is Associated with Cardiac Arrhythmia
1999 Standout
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
Nanog Is the Gateway to the Pluripotent Ground State
2009 StandoutNobel
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel
A minK–HERG complex regulates the cardiac potassium current IKr
1997 Nature
PIWI-interacting small RNAs: the vanguard of genome defence
2011
The histone variant macroH2A suppresses melanoma progression through regulation of CDK8
2010 Nature
Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1
2011 StandoutNatureNobel
Vascularized and functional human liver from an iPSC-derived organ bud transplant
2013 StandoutNature
Cytoplasmically Anchored Plakoglobin Induces a WNT-like Phenotype inXenopus
1997
Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche
2010
Developmental reprogramming after chromosome transfer into mitotic mouse zygotes
2007 Nature
X chromosome reactivation and regulation in cloned embryos
2005
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis
2006
Elite and stochastic models for induced pluripotent stem cell generation
2009 StandoutNatureNobel
Differential molecular interactions of β-catenin and plakoglobin in adhesion, signaling and cancer
1998
Tpt1 Activates Transcription of oct4 and nanog in Transplanted Somatic Nuclei
2007 StandoutNobel
Axin Directly Interacts with Plakoglobin and Regulates Its Stability
1999
Mechanisms of nuclear reprogramming by eggs and oocytes: a deterministic process?
2011 StandoutNobel
Desmosomes: Intercellular Adhesive Junctions Specialized for Attachment of Intermediate Filaments
1998
Fah Knockout Animals as Models for Therapeutic Liver Repopulation
2017
5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming
2011
Oct4-Induced Pluripotency in Adult Neural Stem Cells
2009
The mechanosensory protein MEC-6 is a subunit of the C. elegans touch-cell degenerin channel
2002 StandoutNatureNobel
Epithelial–mesenchymal transitions in tumour progression
2002 Standout
Argonaute proteins: functional insights and emerging roles
2013
Pluripotency and Cellular Reprogramming: Facts, Hypotheses, Unresolved Issues
2010
Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytes
2011 StandoutNobel
Pluripotent stem cell-derived hepatocyte-like cells
2014
Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming
2008
Differential interaction of plakoglobin and β-catenin with the ubiquitin-proteasome system
2000 StandoutNobel
Reprogramming after Chromosome Transfer into Mouse Blastomeres
2009
Multiple small RNA pathways regulate the silencing of repeated and foreign genes in C. elegans
2013 StandoutNobel
Germ cell specification in mice
2009
Small RNA-Mediated Quiescence of Transposable Elements in Animals
2010
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
2003 Standout
Generation of germline-competent induced pluripotent stem cells
2007 StandoutNatureNobel
IsK and KvLQT1: Mutation in Either of the Two Subunits of the Slow Component of the Delayed Rectifier Potassium Channel Can Cause Jervell and Lange-Nielsen Syndrome
1997
Nuclear transplantation: lessons from frogs and mice
2002
The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing
2009
Genomic Structure of Three Long QT Syndrome Genes:KVLQT1, HERG,andKCNE1
1998
De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes
2008
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Mouse liver repopulation with hepatocytes generated from human fibroblasts
2014 Nature
Nuclei of Adult Mammalian Somatic Cells Are Directly Reprogrammed to oct-4 Stem Cell Gene Expression by Amphibian Oocytes
2003 StandoutNobel
A Fresh Look at iPS Cells
2009 StandoutNobel
DNA demethylation is necessary for the epigenetic reprogramming of somatic cell nuclei
2004 StandoutNobel
IGF-II induces rapid β-catenin relocation to the nucleus during epithelium to mesenchyme transition
2001
Epigenetic reprogramming in early mammalian development and following somatic nuclear transfer
2003
Oct-3/4 is a dose-dependent oncogenic fate determinant
2003
Nuclear reprogramming and pluripotency
2006 Nature
Efficiencies and Mechanisms of Nuclear Reprogramming
2010 StandoutNobel
Removing the Vertebrate-Specific TBP N Terminus Disrupts Placental β2m-Dependent Interactions with the Maternal Immune System
2002 StandoutNobel
Chromatin modification and epigenetic reprogramming in mammalian development
2002
Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes
2010
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells
2010
Nuclear reprogramming of cloned embryos and its implications for therapeutic cloning
2007
Synergism between DNA methylation and macroH2A1 occupancy in epigenetic silencing of the tumor suppressor gene p16(CDKN2A)
2010
Mice cloned from olfactory sensory neurons
2004 StandoutNatureNobel
MOV10 RNA Helicase Is a Potent Inhibitor of Retrotransposition in Cells
2012
The histone variant macroH2A is an epigenetic regulator of key developmental genes
2009
The Armadillo Family of Structural Proteins
1998
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Switching stem cell state through programmed germ cell reprogramming
2011
Stem cell pluripotency and transcription factor Oct4
2002
Simultaneous gene quantitation of multiple genes in individual bovine nuclear transfer blastocysts
2007
Nuclear Reprogramming in Cells
2008 StandoutScienceNobel
Nuclei of Embryonic Stem Cells Reprogram Somatic Cells
2004
Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal
2015 StandoutNobel
Pluripotential Reprogramming of the Somatic Genome in Hybrid Cells Occurs with the First Cell Cycle
2007
How to Improve the Success Rate of Mouse Cloning Technology
2010
Mutation of the Gene for I sK Associated With Both Jervell and Lange-Nielsen and Romano-Ward Forms of Long-QT Syndrome
1998
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Histone variant macroH2A confers resistance to nuclear reprogramming
2011 StandoutNobel
Nuclear reprogramming and stem cell creation
2003 StandoutNobel
The Oct4 homologue PouV and Nanog regulate pluripotency in chicken embryonic stem cells
2007
A bacterial Argonaute with noncanonical guide RNA specificity
2016 StandoutNobel
Orphan Nuclear Receptor GCNF Is Required for the Repression of Pluripotency Genes during Retinoic Acid-Induced Embryonic Stem Cell Differentiation
2005
Identification of a deletion in plakoglobin in arrhythmogenic right ventricular cardiomyopathy with palmoplantar keratoderma and woolly hair (Naxos disease)
2000 Standout
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
2012 StandoutNobel
Mobilization of LINE-1 retrotransposons is restricted by Tex19.1 in mouse embryonic stem cells
2017
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells
2012 StandoutNobel
Histone Code Modifications on Pluripotential Nuclei of Reprogrammed Somatic Cells
2004
Reprogramming Efficiency Following Somatic Cell Nuclear Transfer Is Influenced by the Differentiation and Methylation State of the Donor Nucleus
2006
From Nuclear Transfer to Nuclear Reprogramming: The Reversal of Cell Differentiation
2006 StandoutNobel
Defining the Interactions Between Intermediate Filaments and Desmosomes
1998
Characterization of somatic cell nuclear reprogramming by oocytes in which a linker histone is required for pluripotency gene reactivation
2010 StandoutNobel
Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline
2010 StandoutNobel
Roles of plakoglobin end domains in desmosome assembly
1997
The Amino-terminal Domain of Desmoplakin Binds to Plakoglobin and Clusters Desmosomal Cadherin–Plakoglobin Complexes
1997
Differential Nuclear Translocation and Transactivation Potential of β-Catenin and Plakoglobin
1998
Requirement for β-Catenin in Anterior-Posterior Axis Formation in Mice
2000
Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state
2010
Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation
2013 StandoutNobel
Regulation of β-Catenin Levels and Localization by Overexpression of Plakoglobin and Inhibition of the Ubiquitin-Proteasome System
1997
Genome-Wide Distribution of MacroH2A1 Histone Variants in Mouse Liver Chromatin
2010
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
The first half-century of nuclear transplantation
2003 StandoutNobel
Incomplete reactivation ofOct4-related genes in mouse embryos cloned from somatic nuclei
2003
Plakoglobin Suppresses Epithelial Proliferation and Hair Growth in Vivo
2000 StandoutNobel
Genetics of Sensory Mechanotransduction
2002 StandoutNobel
SWI/SNF-Brg1 Regulates Self-Renewal and Occupies Core Pluripotency-Related Genes in Embryonic Stem Cells
2008
Epigenetic reprogramming in mammalian nuclear transfer
2003

Works of K. John McLaughlin being referenced

The Ubiquitin Ligase Ubr2, a Recognition E3 Component of the N-End Rule Pathway, Stabilizes Tex19.1 during Spermatogenesis
2010
Embryonic Heart and Skin Defects in Mice Lacking Plakoglobin
1996
IGF-II Promotes Mesoderm Formation
2000
Oct4 distribution and level in mouse clones: consequences for pluripotency
2002
Inner Ear Defects Induced by Null Mutationof the isk Gene
1996
Induced pluripotent stem cell–derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice
2010 StandoutNobel
Oct4 is required for primordial germ cell survival
2004
Developmental Changes in Histone macroH2A1-Mediated Gene Regulation
2007
Mouse embryos with paternal duplication of an imprinted chromosome 7 region die at midgestation and lack placental spongiotrophoblast
1996
Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway
2010
Rankless by CCL
2026