Citation Impact
Citing Papers
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
2004 Nature
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
1995 StandoutNobel
Cell Death Mechanisms and the Immune System
1991
Inflammation and metabolic disorders
2006 StandoutNature
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
1998 StandoutNature
Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
1992 StandoutNobel
Involvement of Reactive Oxygen Species in Cytokine and Growth Factor Induction of c-fos Expression in Chondrocytes
1995 Standout
Chromatin Modifications and Their Function
2007 Standout
Sequence Alignment of the G-Protein Coupled Receptor Superfamily
1992
Cell-cycle checkpoints and cancer
2004 StandoutNature
Selective Transcription in Response to an Inflammatory Stimulus
2010
The history, properties, and biological effects of cachectin
1988 StandoutNobel
Tying the loose ends together in DNA double strand break repair with 53BP1.
2006
The isoquinoline sulfonamide H7 attenuates radiation-mediated protein kinase C activation and delays the onset of x-ray-induced G2 arrest
1992
Peptide Regulatory Factors
1989
Induction of Tumor Necrosis Factor α Expression in Human T Lymphocytes Following Ionizing Gamma Irradiation
1996
Tumor necrosis factor and its receptors in human ovarian cancer. Potential role in disease progression.
1993
Synthesis and secretion of macrophage colony stimulating factor by mature human monocytes and human monocytic THP-1 cells induced by human serum albumin derivatives modified with methylglyoxal and glucose-derived advanced glycation endproducts
1996
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
1992 StandoutNature
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
The stress-activated protein kinase subfamily of c-Jun kinases
1994 StandoutNature
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
1994 StandoutNature
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
1998 StandoutNature
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
1994 StandoutNobel
γH2AX and MDC1: Anchoring the DNA-damage-response machinery to broken chromosomes
2006
Immunity, Inflammation, and Cancer
2010 Standout
Association between HLA‐DR2 and Production of Tumour Necrosis Factor α and Interleukin 1 by Mononuclear Cells Activated by Lipopolysaccharide
1988
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
53BP1, an activator of ATM in response to DNA damage
2004
Molecular cloning and expression of a receptor for human tumor necrosis factor
1990
Cell-mediated cytotoxicity
1993 StandoutNobel
γH2AX and cancer
2008
Lymphotoxin ?, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface
1993
Regulation of Expression of the Human Monocyte Chemotactic Protein-1 Receptor (hCCR2) by Cytokines
1997
Biochemistry and molecular cell biology of diabetic complications
2001 StandoutNature
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
1995 StandoutNobel
A novel family of genes encoding putative pheromone receptors in mammals
1995 StandoutNobel
Tumour necrosis factor and cancer
2009
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks
2006
Cancer-related inflammation
2008 StandoutNature
Synthesis and secretion of tumour necrosis factor-α by human monocytic THP-1 cells and chemotaxis induced by human serum albumin derivatives modified with methylglyoxal and glucose-derived advanced glycation endproducts
1997
The inflammatory reflex
2002 StandoutNature
Crystal structure of a soluble form of the human T cell coreceptor CD8 at 2.6 Å resolution
1992 StandoutNobel
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein
1995 StandoutNatureNobel
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Fas- and Tumor Necrosis Factor-induced Apoptosis Is Inhibited by the Poxvirus crmA Gene Product
1995
Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis.
1994 Standout
Constitutive synthesis of tumor necrosis factor in the thymus.
1992 StandoutNobel
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA
2007 StandoutNobel
An allelic polymorphism within the human tumor necrosis factor alpha promoter region is strongly associated with HLA A1, B8, and DR3 alleles.
1993
Constitutive activity of the tumor necrosis factor promoter is canceled by the 3' untranslated region in nonmacrophage cell lines; a trans-dominant factor overcomes this suppressive effect.
1992 StandoutNobel
The Detection and Discovery of Glycan Motifs in Biological Samples Using Lectins and Antibodies: New Methods and Opportunities
2015
Involvement of the sphingomyelin pathway in autocrine tumor necrosis factor signaling for human immunodeficiency virus production in chronically infected HL-60 cells
1994
Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation.
1993 Standout
Inhibition of Protein Kinases Sensitizes Human Tumor Cells to Ionizing Radiation
1992
Transcriptional and post-transcriptional mechanisms involved in the differential expression of LPS-induced IL-1 and TNF mRNA.
1991
Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair
2006
Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2
1997 StandoutNobel
Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific.
1991
Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer.
1994 StandoutNobel
An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death
1996 StandoutScienceNobel
1997 StandoutNobel
Seppuku and Autoimmunity
1992 StandoutScienceNobel
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
1993 StandoutScience
Combinatorial interactions between AP-1 and ets domain proteins contribute to the developmental regulation of the macrophage scavenger receptor gene.
1994
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
Effects of a polymorphism in the human tumor necrosis factor α promoter on transcriptional activation
1997 Standout
Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry
1993
Tumor necrosis factor stimulates multiple serine/threonine protein kinases in Swiss 3T3 and L929 cells. Implication of casein kinase-2 and extracellular signal-regulated kinases in the tumor necrosis factor signal transduction pathway.
1992
Increased tumor necrosis factor alpha mRNA after cellular exposure to ionizing radiation.
1989
Serum levels of tumour necrosis factor-alpha and interleukin-1 beta during leprosy reactional states.
1991
DNA Double-Strand Breaks
2002 StandoutNobel
Significance analysis of microarrays applied to the ionizing radiation response
2001 Standout
Mitogen‐inducible prostaglandin G/H synthase: A new target for nonsteroidal antiinflammatory drugs
1992
Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor
1989
Tumor Necrosis Factor-α Activates the Sphingomyelin Signal Transduction Pathway in a Cell-Free System
1992 Science
Perturbed gap-filling synthesis in nucleotide excision repair causes histone H2AX phosphorylation in human quiescent cells
2007
Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C.
1991
Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85
1984 StandoutNobel
Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level.
1990 StandoutNobel
Metabolism of ubiquitinated histones.
1981 StandoutNobel
A Receptor for Tumor Necrosis Factor Defines an Unusual Family of Cellular and Viral Proteins
1990 Science
Chemical Glycoproteomics
2016 StandoutNobel
Interleukin 10 suppression of monocyte prostaglandin H synthase-2. Mechanism of inhibition of prostaglandin-dependent matrix metalloproteinase production.
1994
Unraveling Function in the TNF Ligand and Receptor Families
1994 StandoutScienceNobel
TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB
1996 StandoutScience
Works of K. Imamura being referenced
Potential Role for 53BP1 in DNA End-joining Repair through Direct Interaction with DNA
2003
Tumor necrosis factor expression in human epithelial tumor cell lines.
1988
Improved lectin ELISA for glycosylation analysis of biomarkers using PS-tag-fused single-chain Fv
2012
Transcriptional and posttranscriptional regulation of tumor necrosis factor gene expression in human monocytes.
1988
Recombinant human tumor necrosis factor administered as a five-day continuous infusion in cancer patients: phase I toxicity and effects on lipid metabolism.
1988
Engineering of the glycan-binding specificity of Agrocybe cylindracea galectin towards α(2,3)-linked sialic acid by saturation mutagenesis
2011
Effect of tumor necrosis factor on GTP binding and GTPase activity in HL-60 and L929 cells.
1988
Colony-stimulating factor 1 activates protein kinase C in human monocytes.
1990
Functional expression of the macrophage colony-stimulating factor receptor in human THP-1 monocytic leukemia cells
1992
Phospholipase A2 activation and autoinduction of tumor necrosis factor gene expression by tumor necrosis factor.
1990
Functional expression of the macrophage colony-stimulating factor receptor in human THP-1 monocytic leukemia cells
1992
Colony-stimulating factor 1-induced Na+ influx into human monocytes involves activation of a pertussis toxin-sensitive GTP-binding protein.
1988
Role of arachidonic acid metabolism in transcriptional induction of tumor necrosis factor gene expression by phorbol ester.
1989
Induction of tumor necrosis factor expression and resistance in a human breast tumor cell line.
1987
Expression of tumor necrosis factor receptors on human monocytes and internalization of receptor bound ligand.
1987