Citation Impact
Citing Papers
Loss of cryptochrome reduces cancer risk in p53 mutant mice
2009 StandoutNobel
Self-destruction and tolerance in resistance of mammalian cells to alkylation damage
1992
DNA excision-repair processes in human cells can eliminate the cytotoxic and mutagenic consequences of ultraviolet irradiation
1979
Resistance of cultured human fibroblasts and other cells to purine and pyrimidine analogues in relation to mutagenesis detection
1974
A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage
2003
A checkpoint regulates the rate of progression through S phase in S. cerevisiae in Response to DNA damage
1995 StandoutNobel
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
2005 StandoutNature
Induction of the Escherichia coli lactose operon selectively increases repair of its transcribed DNA strand
1989 Nature
Mammalian single-strand break repair: Mechanisms and links with chromatin
2006
Induction of oxidative DNA base damage in human skin cells by UV and near visible radiation
1997
Polymorphisms in the DNA repair genes XRCC1 and ERCC2 and biomarkers of DNA damage in human blood mononuclear cells
2000
Cell-cycle checkpoints and cancer
2004 StandoutNature
Transcription-coupled DNA repair: two decades of progress and surprises
2008
A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome
1990
Intermediate (6-4) photoproduct repair in Chinese hamster V79 mutant V-H1 correlates with intermediate levels of DNA incision and repair replication
1989
NUCLEOTIDE EXCISION REPAIR
1993 StandoutNobel
Translesion DNA synthesis in the dihydrofolate reductase domain of UV-irradiated CHO cells
1992
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
2005 StandoutNature
(6-4) Photoproducts and not cyclobutane pyrimidine dimers are the main UV-induced mutagenic lesions in Chinese hamster cells
1992
Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA-damaging agents
1992 StandoutNobel
Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA
1997 StandoutNobel
Oncogene Activation in Chemical Carcinogenesis
1988
Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast
1994 StandoutNatureNobel
Mutation of the mouse klotho gene leads to a syndrome resembling ageing
1997 StandoutNature
Telomeres shorten during ageing of human fibroblasts
1990 StandoutNatureNobel
Different forms of TFIIH for transcription and DNA repair: Holo-TFIIH and a nucleotide excision repairosome
1995 StandoutNobel
Codominance associated with overexpression of certain XPD mutations
2001
ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes
1992
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice
1999 StandoutNobel
Xeroderma Pigmentosum p48 Gene Enhances Global Genomic Repair and Suppresses UV-Induced Mutagenesis
2000
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Molecular analysis of ERCC2 mutations in the repair deficient hamster mutants UVL-1 and V-H1
1997
Rodent UV-Sensitive Mutant Cell Lines in Complementation Groups 6-10 Have Normal General Excision Repair Activity
1997
Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair
1993 StandoutNobel
The XPD complementation group
1992
Where transcription meets repair
1994 StandoutNobel
Dual role of TFIIH in DNA excision repair and in transcription by RNA polymerase II
1994 StandoutNatureNobel
Somatic cell genetics approach to dissecting mammalian DNA repair
1989
Site-specific DNA repair at the nucleosome level in a yeast minichromosome
1990
Enhanced UV-induced mutagenesis in the UV61 cell line, the Chinese hamster homologue of Cockayne's syndrome B, is associated with defective transcription coupled repair of cyclobutane pyrimidine dimers
1998
Isolation of the functional human excision repair gene ERCC5 by intercosmid recombination
1990
Flow cytometric analysis of X-ray sensitivity in ataxia telangiectasia
1989
The XRCC1 399 glutamine allele is a risk factor for adenocarcinoma of the lung
2001
Mutagen-sensitive cell lines are obtained with high frequency in V79 Chinese cells
1987
Contribution of incorporated 5-bromodeoxyuridine in DNA to the frequencies of sister-chromatid exchanges induced by inhibitors of poly-(ADP-ribose)-polymerase
1981
Multiple hypersensitivity to mutagens in a cell strain (46BR) derived from a patient with immuno-deficiencies
1983
Telomere length predicts replicative capacity of human fibroblasts.
1992 StandoutNobel
Elevated spontaneous mutation rate in Bloom syndrome fibroblasts.
1981
Brca2 (XRCC11) Deficiency Results in Radioresistant DNA Synthesis and a Higher Frequency of Spontaneous Deletions
2002
An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.
1993 StandoutNobel
p53 Mutations in Human Cancers
1991 StandoutScience
Establishment of mouse embryo cells in vitro
1977
Increased Rate of Base Substitution in a Hamster Mutator Strain Obtained during Serial Selection for Gene Amplification
1990
Novel Chinese hamster ultraviolet-sensitive mutants for excision repair form complementation groups 9 and 10.
1991
Restoration of Nucleotide Excision Repair in a Helicase-Deficient XPD Mutant from Intragenic Suppression by a Trichothiodystrophy Mutation
2001 StandoutNobel
Altering Genotype and Phenotype by DNA-Mediated Gene Transfer
1980 StandoutScienceNobel
Cell Cycle-Dependent Strand Bias for UV-Induced Mutations in the Transcribed Strand of Excision Repair-Proficient Human Fibroblasts but Not in Repair-Deficient Cells
1991
Site and strand specificity of UVB mutagenesis in the SUP4-o gene of yeast.
1990
A link between double-strand break-related repair and V(D)J recombination: the scid mutation.
1991
In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in Xeroderma pigmentosum patients
1997 StandoutNobel
Substrate and Temperature Dependence of DNA Photolyase Repair Activity Examined with Ultrafast Spectroscopy
1997 StandoutNobel
Xeroderma pigmentosum complementation group C cells remove pyrimidine dimers selectively from the transcribed strand of active genes.
1991
Analysis of repair of cyclobutane pyrimidine dimers and pyrimidine 6-4 pyrimidone photoproducts in transcriptionally active and inactive genes in Chinese hamster cells.
1994
Quality Control by DNA Repair
1999 StandoutScienceNobel
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
Domainal evolution of a prokaryotic DNA repair protein and its relationship to active-transport proteins
1986 StandoutNatureNobel
Biological and biochemical consequences of the human ERCC-1 repair gene after transfection into a repair-deficient CHO cell line
1987
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Structural alterations of DNA ligase I in Bloom syndrome.
1987 StandoutNobel
Xeroderma Pigmentosum Complementation Group C Cells Remove Pyrimidine Dimers Selectively from the Transcribed Strand of Active Genes
1991
Differential Repair of the Two Major UV-Induced Photolesions in Trichothiodystrophy Fibroblasts
2004
Substrate spectrum of human excinuclease: repair of abasic sites, methylated bases, mismatches, and bulky adducts.
1994 StandoutNobel
Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct.
1996 StandoutNobel
Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrene in the coding region of the HPRT gene.
1990
Evidence for a repair enzyme complex involving ERCC1 and complementing activities of ERCC4, ERCC11 and xeroderma pigmentosum group F.
1993
Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53
1998 StandoutScience
Control of skin cancer by the circadian rhythm
2011 StandoutNobel
Transcription-coupled repair removes both cyclobutane pyrimidine dimers and 6-4 photoproducts with equal efficiency and in a sequential way from transcribed DNA in xeroderma pigmentosum group C fibroblasts.
1995
Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange.
1990
Ataxia-telangiectasia: an inherited disorder of ionizing-radiation sensitivity in man
1987
Cellular Senescence revisited: a review
1987
Assembly, subunit composition, and footprint of human DNA repair excision nuclease
1998 StandoutNobel
A Novel DNA Repair Response Is Induced in Human Cells Exposed to Ionizing Radiation at the G 1 /S-Phase Border
1996
Gene- and strand-specific repair in vitro: partial purification of a transcription-repair coupling factor.
1991 StandoutNobel
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
Molecular characterization of the human excision repair gene : cDNA cloning and amino acid homology with the yeast DNA repair gene
1986
THE BIOLOGY OF THE (6–4) PHOTOPRODUCT
1989
Increased rate of base substitution in a hamster mutator strain obtained during serial selection for gene amplification.
1990
Identification of the eleventh complementation group of UV-sensitive excision repair-defective rodent mutants.
1992
Significance analysis of microarrays applied to the ionizing radiation response
2001 Standout
Molecular analysis of spontaneous somatic mutants
1977 StandoutNatureNobel
HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease.
1994 StandoutNobel
Yeast RAD3 protein binds directly to both SSL2 and SSL1 proteins: implications for the structure and function of transcription/repair factor b.
1994 StandoutNobel
Rejoining Kinetics of DNA Single- and Double-Strand Breaks in Normal and DNA Ligase-Deficient Cells after Exposure to Ultraviolet C and Gamma Radiation: An Evaluation of Ligating Activities Involved in Different DNA Repair Processes
1999
Worthy of a detour
1982 StandoutNatureNobel
Mechanisms of tolerance to DNA lesions in mammalian cells
1981
Human DNA Repair Genes
2001 StandoutScienceNobel
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
A multisubunit complex containing the SWI1/ADR6,SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated fromyeast.
1994 StandoutNobel
ERCC2: cDNA cloning and molecular characterization of a human nucleotide excision repair gene with high homology to yeast RAD3.
1990
A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma.
1991 Standout
Validation of conditions for efficient detection of HPRT and APRT mutations in suspension-cultured chinese hamster ovary cells
1980
Molecular cloning of the human nucleotide-excision-repair gene ERCC4.
1994 StandoutNobel
DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSα/hMutSβ ratio and reduces the efficiency of base–base mismatch repair
1997 StandoutNobel
Extension of Life-Span by Introduction of Telomerase into Normal Human Cells
1998 StandoutScience
Cockayne syndrome group B protein enhances elongation by RNA polymerase II
1997 StandoutNobel
Works of J.W.I.M. Simons being referenced
Development of a liquid-holding technique for the study of DNA-repair in human diploid fibroblasts
1979
Linear dose —response relationships after prolonged expression times in V-79 Chinese hamster cells
1976
The use of correction factors in the determination of mutant frequencies in populations of human diploid skin fibroblasts
1976
A mutational assay system for L5178Y mouse lymphoma cells, using hypoxanthine-guanine-phosphoribosyl-transferase (HGPRT) -deficiency as marker. The occurrence of a long expression time for mutations induced by X-rays and EMS
1975
The effect of calf serum on the toxicity of 8-azaguanine
1975
Dose-response relationships for mutants in mammalian somatic cells in vitro
1974
The role of metabolic cooperation in selection of hypoxanthine-guanine-phosphoribosyl-transferase (HG-PRT)-deficient mutants from diploid mammalian cell strains
1972
A Chinese hamster ovary cell mutant (EM-C11) with sensitivity to simple alkylating agents and a very high level of sister chromatid exchanges
1992
Identification of a new seventh complementation group of UV-sensitive mutants in Chinese hamster cells
1988
Nucleotide sequence determination of point mutations at the mouse HPRT locus using in vitro amplification of HPRT mRNA sequences
1988
Strand specificity for UV-induced DNA repair and mutations in the Chinese hamster HPRT gene
1991
Phenotypic heterogeneity within the first complementation group of UV-sensitive mutants of Chinese hamster cell lines
1988
DNA repair characteristics and mutability of the UV-sensitive V79 Chinese hamster cell mutant V-B11 (complementation group 7)
1991
Recovery of growth-arrested human fibroblasts from UV-induced lethal damage is inhibited by low cell density or sodium butyrate
1985
Relationship between cell killing, chromosomal aberrations, sister-chromatid exchanges and point mutations induced by monofunctional alkylating agents in Chinese hamster cells a correlation with different ethylation products in DNA
1984
Differential response of human fibroblasts to the cytotoxic and mutagenic effects of UV radiation in different phases of the cell cycle
1985
Study on the variation in X-ray sensitivity of human diploid skin fibroblasts
1982
Analysis of repair processes by the determination of the induction of cell killing and mutations in two repair-deficient Chinese hamster ovary cell lines
1986
DNA Strand Specificity for UV-Induced Mutations in Mammalian Cells
1989
Transformation of C3H10T1/2 cells by N-ethyl-N-nitrosourea occurs as a single, low frequency, mutation-like event
1986
Ataxia-telangiectasia-like Chinese hamster V79 cell mutants with radioresistant DNA synthesis, chromosomal instability, and normal DNA strand break repair.
1989
DNA strand specificity for UV-induced mutations in mammalian cells.
1989
The wavelength dependence of u.v.-induced pyrimidine dimer formation, cell killing and mutation induction in human diploid skin fibroblasts
1986
The use of frequency distributions of cell diameters to characterize cell populations in tissue culture
1967
Characterization of an X-ray-hypersensitive mutant of V79 Chinese hamster cells
1988
Attempts to detect ataxia telangiectasia (AT) heterozygotes by cytogenetical techniques
1982