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Induction of nitric oxide synthase in asthma
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Relation between FEV1 and peak expiratory flow in patients with chronic airflow obstruction.
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Effect of high dose inhaled fluticasone propionate on airway inflammation in asthma.
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Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials
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Identification of T lymphocytes, Macrophages, and Activated Eosinophils in the Bronchial Mucosa in Intrinsic Asthma: Relationship to Symptoms and Bronchial Responsiveness
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Oral Corticosteroid Therapy for Patients with Stable Chronic Obstructive Pulmonary Disease
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Bronchial biopsy evidence for leukocyte infiltration and upregulation of leukocyte-endothelial cell adhesion molecules 6 hours after local allergen challenge of sensitized asthmatic airways.
1994
Inflammatory cells and eicosanoid mediators in subjects with late asthmatic responses and increases in airway responsiveness
1992
Airway Mucosal Inflammation Even in Patients with Newly Diagnosed Asthma
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Eosinophilic and neutrophilic inflammation in asthma, chronic bronchitis, and chronic obstructive pulmonary disease
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Effect of Inhaled Formoterol and Budesonide on Exacerbations of Asthma
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Expression of laminins in the airways in various types of asthmatic patients: a morphometric study.
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Granulocyte macrophage colony-stimulating factor contributes to enhanced monocyte survival in chronic atopic dermatitis.
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Repair mechanisms in asthma
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High resolution computed tomography in asthma
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Airway smooth muscle cell culture: application to studies of airway wall remodelling and phenotype plasticity in asthma
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Effect of Cessation of Exposure to Toluene Diisocyanate (TDI) on Bronchial Mucosa of Subjects with TDI-induced Asthma
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Inhaled Corticosteroid Improves Bronchial Reactivity and Decreases Symptoms in Patients With Mitral Stenosis
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Cyclophosphamide in the Treatment of Idiopathic Pulmonary Fibrosis
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Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma.
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Interleukin-17 and Type 17 Helper T Cells
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Airway wall thickness in patients with near fatal asthma and control groups: assessment with high resolution computed tomographic scanning
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Quantitation of Mast Cells and Eosinophils in the Bronchial Mucosa of Symptomatic Atopic Asthmatics and Healthy Control Subjects Using Immunohistochemistry
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Cyclosporine A inhibits airway reactivity and remodeling after chronic antigen challenge in cats.
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The development of allergic inflammation
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Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma
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“Helper” (CD4 + ) T Cells and Eosinophils in Allergy and Asthma
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Pathogenesis of Mucous Cell Metaplasia in a Murine Asthma Model
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The Appearance of Hypodense Eosinophils in Antigen-dependent Late Phase Asthma
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IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines
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Myofibroblast involvement in the allergen-induced late response in mild atopic asthma.
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Airway Mucosal Inflammation in Occupational Asthma Induced by Toluene Diisocyanate
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Lung inflammation and epithelial changes in a murine model of atopic asthma.
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Elevated substance P content in induced sputum from patients with asthma and patients with chronic bronchitis.
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Increased levels of CD34+ hemopoietic progenitor cells in atopic subjects.
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Airway Hyperresponsiveness, Increased Intracellular Spaces of Bronchial Epithelium, and Increased Infiltration of Eosinophils and Lymphocytes in Bronchial Mucosa in Asthma
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Cell cultures from bronchial subepithelial myofibroblasts enhance eosinophil survival in vitro
1996
Perception of bronchial obstruction in asthmatic patients. Relationship with bronchial eosinophilic inflammation and epithelial damage and effect of corticosteroid treatment.
1995
Clinical deterioration in patients with idiopathic pulmonary fibrosis: Causes and assessment
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Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines.
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Comparison of leukocyte counts in sputum, bronchial biopsies, and bronchoalveolar lavage.
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Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: Comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness
1991
Controlled trial of oral prednisone in outpatients with acute COPD exacerbation.
1996
Intraepithelial Mast Cells in Allergic and Nonallergic Asthma: Assessment Using Bronchial Brushings
1993
Increased Levels of Serum Interferon-gamma in Pulmonary Sarcoidosis and Relationship with Response to Corticosteroid Therapy
1991
Determinants of survival in idiopathic pulmonary fibrosis.
1994
Airway inflammation after removal from the causal agent in occupational asthma due to high and low molecular weight agents
1994
Recent advances in the immunology of interstitial lung disease
1991
Inflammatory Cells and Eosinophilic Activity in Asthmatics Investigated by Bronchoalveolar Lavage: The Effects of Antiasthmatic Treatment with Budesonide or Terbutaline
1990
Indirect evidence of bronchial inflammation assessed by titration of inflammatory mediators in BAL fluid of patients with asthma
1991
Idiopathic pulmonary fibrosis
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Granulocyte activation markers in induced sputum: comparison between chronic obstructive pulmonary disease, asthma, and normal subjects.
1997
Peripheral blood CD4 but not CD8 t-lymphocytes in patients with exacerbation of asthma transcribe and translate messenger RNA encoding cytokines which prolong eosinophil survival in the context of a Th2-type pattern: effect of glucocorticoid therapy.
1995
Eosinophils: Biology and Role in Disease
1995
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
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Immunological Aspects of Allergic Asthma
1994
Inhibitory Effect of the TRFK-5 Anti-IL-5 Antibody in a Guinea Pig Model of Asthma
1993
Cellular and Biochemical Analysis of Induced Sputum from Asthmatic and from Healthy Subjects
1993
Effects of theophylline on inflammatory cells and cytokines in asthmatic subjects: a placebo-controlled parallel group study
1996
Expression of endothelial and leukocyte adhesion molecules intercellular adhesion molecule-1, E-selectin, and vascular cell adhesion molecule-1 in the bronchial mucosa in steady-state and allergen-induced asthma
1993
Modulation by interleukin-4 of cytokine release from mononuclear phagocytes in asthma
1994
Allergen exposure induces the activation of allergen‐specific Th2 cells in the airway mucosa of patients with allergic respiratory disorders
1993
The Structure of Large and Small Airways in Nonfatal and Fatal Asthma
1993
The potential role of tumour necrosis factor a in asthma
1993
Transcription Factor GATA-3 Is Differentially Expressed in Murine Th1 and Th2 Cells and Controls Th2-specific Expression of the Interleukin-5 Gene
1997
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsìveness, and the late asthmatic response
2000 Standout
Eosinophilic inflammation is associated with elevation of interleukin-5 in the airways of patients with spontaneous symptomatic asthma
1995
Eosinophil survival activity identified as interleukin-5 is associated with eosinophil recruitment and degranulation and lung injury twenty-four hours after segmental antigen lung challenge
1993
Effect of murine recombinant interleukin‐5 on bronchial reactivity in guinea‐pigs
1993
Molecular basis for selective eosinophil trafficking in asthma: A multistep paradigm☆☆☆
1999
β-Arrestin-2 regulates the development of allergic asthma
2003 StandoutNobel
Markers of Mucus Secretion and DNA Levels in Induced Sputum from Asthmatic and from Healthy Subjects
1993
Predominant TH2-like Bronchoalveolar T-Lymphocyte Population in Atopic Asthma
1992 Standout
Relationships among numbers of bronchoalveolar lavage cells expressing messenger ribonucleic acid for cytokines, asthma symptoms, and airway methacholine responsiveness in atopic asthma
1993
The role of T lymphocytes in the pathogenesis of asthma
2003
Inhaled beclomethasone dipropionate downregulates airway lymphocyte activation in atopic asthma.
1994
sVCAM-1 levels after segmental antigen challenge correlate with eosinophil influx, IL-4 and IL-5 production, and the late phase response.
1995
Synthesis and evaluation of novel chromone analogs for their inhibitory activity against interleukin-5
2010
Airways Remodeling Is a Distinctive Feature of Asthma and Is Related to Severity of Disease
1997
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
1998 StandoutNature
Eosinophilic Airway Inflammation during Exacerbation of Asthma and Its Treatment with Inhaled Corticosteroid
1991
Effects of Glucocorticoids on Humoral and Cellular Immunity and on Airway Inflammation in Patients with Steroid-Dependent Intractable Asthma
1993
Asthma
2000 Standout
Airway Inflammation in Mild Intermittent and in Persistent Asthma
1998
Intraluminal Airway Inflammation in Chronic Bronchitis: Characterization and Correlation with Clinical Parameters
1989
Selective Regulation of Expression of Surface Adhesion Molecules Mac-1, L-selectin, and VLA-4 on Human Eosinophils and Neutrophils
1993
Effect of Inhaled Interleukin-5 on Airway Hyperreactivity and Eosinophilia in Asthmatics
1998
Airway Inflammation in Occupational Asthma
1994
Inflammation and Airway Function in Asthma
1998
Eosinophil's Role Remains Uncertain as Anti–Interleukin-5 only Partially Depletes Numbers in Asthmatic Airway
2003
Eotaxin mRNA and Protein Expression in Chronic Sinusitis and Allergen-induced Nasal Responses in Seasonal Allergic Rhinitis
1997
Eosinophil-associated TGF- β 1 mRNA Expression and Airways Fibrosis in Bronchial Asthma
1997
CD34 + /Interleukin-5R α Messenger RNA + Cells in the Bronchial Mucosa in Asthma: Potential Airway Eosinophil Progenitors
1999
Cytokines as Mediators of Chronic Asthma
1994
Increases in Activated T Lymphocytes, Eosinophils, and Cytokine mRNA Expression for Interleukin-5 and Granulocyte/Macrophage Colony-stimulating Factor in Bronchial Biopsies after Allergen Inhalation Challenge in Atopic Asthmatics
1993
3. Epithelial Cells: Barrier Functions and Shedding-Restitution Mechanisms
1996
Transforming Growth Factor- β Expression in Mucosal Biopsies in Asthma and Chronic Bronchitis
1997
Withdrawal of Chronic Systemic Corticosteroids in Patients with COPD
2000
Enhanced Production of Oxygen Radicals in Nocturnal Asthma
1992
Mechanisms of persistent airway inflammation in asthma. A role for T cells and T-cell products.
1995
c-fos Proto-oncogene Expression in Bronchial Biopsies of Asthmatics
1992
Dissociation between Airway Inflammation and Airway Hyperresponsiveness in Allergic Asthma
1998
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Relationship between IL-4 and IL-5 mRNA Expression and Disease Severity in Atopic Asthma
1997
Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo.
1995
The measurement of reticular basement membrane and submucosal collagen in the asthmatic airway
1997
The effect of inhaled sodium cromoglycate on cellular infiltration into the bronchial mucosa and the expression of adhesion molecules in asthmatics
1997
Activation of A3 adenosine receptors on human eosinophils elevates intracellular calcium
1996 StandoutNobel
Idiopathic Pulmonary Fibrosis
2000
Eosinophil cationic protein(ECP) and eosinophil protein X (EXP) concentrations in serum and bronchial lavage fluid in asthma. effect of prednisolone treatment.
1995
Asthma : Mechanisms of Disease Persistence and Progression
2004
Dendritic cells in normal and asthmatic airways: expression of the α subunit of the high affinity immunoglobulin E receptor (FcεRI‐α)
1996
Randomised controlled trial comparing prednisolone alone with cyclophosphamide and low dose prednisolone in combination in cryptogenic fibrosing alveolitis.
1989
Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis.
1987
Bronchodilator reversibility, exercise performance and breathlessness in stable chronic obstructive pulmonary disease
1992
Requirement for IL-13 Independently of IL-4 in Experimental Asthma
1998 StandoutScience
Moderately severe chronic airflow obstruction. Can corticosteroids slow down obstruction?
1988
The bronchial epithelium as a target for inflammatory attack in asthma
1992
Lung damage and airway remodelling in severe asthma
2011
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Immunoreactivity for interleukin 3 and 5 and granulocyte/macrophage colony-stimulating factor of intestinal mucosa in bronchial asthma.
1995
The relationship between inflammation and hyperreactivity of the airways in asthma
1993
Increased numbers of dendritic cells in the bronchial mucosa of atopic asthmatic patients: downregulation by inhaled corticosteroids
1996
Anti-inflammatory effects of inhaled beclomethasone dipropionate in nonatopic asthmatics
1996
A subset of dendritic cells induces CD4+ T cells to produce IFN-γ by an IL-12–independent but CD70-dependent mechanism in vivo
2007 StandoutNobel
Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.
1996
Activated memory T helper cells in bronchoalveolar lavage fluid from patients with atopic asthma: relation to asthma symptoms, lung function, and bronchial responsiveness.
1993
Expression and generation of interleukin-8, IL-6 and granulocyte-macrophage colony-stimulating factor by bronchial epithelial cells and enhancement by IL-1 beta and tumour necrosis factor-alpha.
1992
Idiopathic Pulmonary Fibrosis: Prevailing and Evolving Hypotheses about Its Pathogenesis and Implications for Therapy
2001 Standout
New perspectives on basic mechanisms in lung disease. 1. Lung injury, inflammatory mediators, and fibroblast activation in fibrosing alveolitis.
1992
ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
2006 Standout
Interleukin-5, eosinophils, and disease
1992
Non-steroid agents for idiopathic pulmonary fibrosis
2010
Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils.
1996
A Novel T Cell-Regulated Mechanism Modulating Allergen-Induced Airways Hyperreactivity in BALB/c Mice Independently of IL-4 and IL-5
1998
Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils
1997 StandoutNobel
Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice.
1995
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Modulation of adhesion molecule expression on endothelial cells during the late asthmatic reaction: role of macrophage-derived tumour necrosis factor-alpha
1993
Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model.
1996 Standout
Corticosteroid treatment in pulmonary sarcoidosis: do serial lavage lymphocyte counts, serum angiotensin converting enzyme measurements, and gallium-67 scans help management?
1986
Th1/Th2 cells
2007
Expression of Interleukin 9 in the Lungs of Transgenic Mice Causes Airway Inflammation, Mast Cell Hyperplasia, and Bronchial Hyperresponsiveness
1998
β-Arrestin-2 regulates the development of allergic asthma
2003 StandoutNobel
Airway eosinophilia and expression of interleukin‐5 protein in asthma and in exacerbations of chronic bronchitis
1996
Pathology of asthma
1992
Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma
1988
Interleukin-13: Central Mediator of Allergic Asthma
1998 StandoutScience
Airways hyperresponsiveness, bronchodilator response, allergy and smoking predict improvement in FEV1 during long-term inhaled corticosteroid treatment. Dutch CNSLD Study Group
1993
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
Induction of Airway Mucus Production By T Helper 2 (Th2) Cells: A Critical Role For Interleukin 4 In Cell Recruitment But Not Mucus Production
1997
Platelet-derived growth factor-beta mRNA in human alveolar macrophages in vivo in asthma
1994
Lung function and immunopathological changes after inhaled corticosteroid therapy in asthma
1992
The relationship between bronchial immunopathology and hyperresponsiveness in asthma
1990
Changes in bronchoalveolar lavage inflammatory cells in asthmatic patients treated with high dose inhaled beclomethasone dipropionate
1993
The role of interleukin‐5, interleukin‐8 and RANTES in the chemotactic attraction of eosinophils to the allergic lung
1999
Relationship between the inflammatory infiltrate in bronchial biopsy specimens and clinical severity of asthma in patients treated with inhaled steroids.
1996
Bronchial biopsies and airway inflammation
1996
Altered accessory cell function of alveolar macrophages: a possible mechanism for induction of Th2 secretory profile in idiopathic pulmonary fibrosis
1997
Expression of growth factors and remodelling of the airway wall in bronchial asthma
1998
Airway and lung elastic fibre is not reduced in asthma nor in asthmatics following corticosteroid treatment
1995
Genetic Susceptibility to Asthma — Bronchial Hyperresponsiveness Coinherited with a Major Gene for Atopy
1995
Altered compartimentalization of transforming growth factor‐β in asthmatic airways
1997
IMMUNOLOGIC BASIS OF ANTIGEN-INDUCED AIRWAY HYPERRESPONSIVENESS
1999
Signal Transducer and Activator of Transcription Factor 6 (Stat6)-deficient Mice Are Protected from Antigen-induced Airway Hyperresponsiveness and Mucus Production
1998
Works of J.V. Collins being referenced
Bronchial Biopsies in Asthma: An Ultrastructural, Quantitative Study and Correlation with Hyperreactivity
1989
Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma.
1991
Interleukin-5 mRNA in Mucosal Bronchial Biopsies from Asthmatic Subjects
1991
SPUTUM INDUCTION FOR DIAGNOSIS OF PNEUMOCYSTIS CARINII PNEUMONIA
1989
Steroid trials in the assessment of reversibility of air flow limitation: a survey of current clinical practice of chest physicians
1991
Eosinophils and Mast Cells in Bronchoalveolar Lavage in Subjects with Mild Asthma: Relationship to Bronchial Hyperreactivity
1988
Psychological changes and improvement in chronic airflow limitation after corticosteroid treatment.
1984
Morphological and secretory properties of bronchoalveolar lavage mast cells in respiratory diseases
1986
294 Eosinophils, T-lymphocytes, mast cells, neutrophils and macrophages in bronchial biopsies from atopic asthmatics: Comparison with atopic non-asthma and relationship to bronchial hyperresponsiveness
1991
Value of chest radiographs in severe acute asthma
1981
Value of serial peak expiratory flow measurements in assessing treatment response in chronic airflow limitation.
1986
293 Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma
1991
EFFECTS OF PREDNISOLONE IN CHRONIC AIRFLOW LIMITATION
1984
Bronchoalveolar lavage in pulmonary fibrosis: comparison of cells obtained with lung biopsy and clinical features
1980
Bronchoalveolar lavage fluid cell counts in cryptogenic fibrosing alveolitis and their relation to therapy.
1980
Airway Function in Healthy Subjects and Patients with Left Heart Disease
1975