Citation Impact

Citing Papers

Tibetans living at sea level have a hyporesponsive hypoxia-inducible factor system and blunted physiological responses to hypoxia
2013 StandoutNobel
Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis
2014
Hypoxia-inducible factor regulates hepcidin via erythropoietin-induced erythropoiesis
2012
Ferroptosis: past, present and future
2020 Standout
Regulation of erythropoiesis by hypoxia-inducible factors
2013
Regulation of Type II Transmembrane Serine Proteinase TMPRSS6 by Hypoxia-inducible Factors
2010 StandoutNobel
Hypoxic regulation of erythropoiesis and iron metabolism
2010
Mechanisms of hypoxia signalling: new implications for nephrology
2019 StandoutNobel
Exosomes/microvesicles: mediators of cancer-associated immunosuppressive microenvironments
2011
Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload†
2009
Applications of CRISPR-Cas Enzymes in Cancer Therapeutics and Detection
2018 StandoutNobel
Common variants in TMPRSS6 are associated with iron status and erythrocyte volume
2009
Dysregulated expression of fatty acid oxidation enzymes and iron‐regulatory genes in livers of Nrf2‐null mice
2012
Targeting the hepcidin–ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation
2011
Iron Overload in Human Disease
2012
Glu332 in the Nicastrin Ectodomain Is Essential for γ-Secretase Complex Maturation but Not for Its Activity
2008
Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels
2009
Chronic kidney disease
2011 Standout
Hepcidin and iron homeostasis
2012
Evidence for a Lack of a Direct Transcriptional Suppression of the Iron Regulatory Peptide Hepcidin by Hypoxia-Inducible Factors
2009
Two to Tango: Regulation of Mammalian Iron Metabolism
2010 Standout
The role of iron and reactive oxygen species in cell death
2013 Standout
Non-viral vectors for gene-based therapy
2014 Standout
Pharmacological targeting of the HIF hydroxylases – A new field in medicine development
2016 StandoutNobel
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state
2015 Standout
Iron and ER stress in neurodegenerative disease
2012
Iron refractory iron deficiency anemia
2013
In vivo genome editing using Staphylococcus aureus Cas9
2015 StandoutNature
Iron regulation by hepcidin
2013
Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling
2012 Standout
Importance of Iron Chelation in Free Radical-Induced Oxidative Stress and Human Disease
2011
Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease
2015
Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins
2012 Standout
Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges
2011
Testosterone Induces Erythrocytosis via Increased Erythropoietin and Suppressed Hepcidin: Evidence for a New Erythropoietin/Hemoglobin Set Point
2013 Standout
The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
2014 Standout
The role of iron in brain ageing and neurodegenerative disorders
2014 Standout
A novel transferrin/TfR2-mediated mitochondrial iron transport system is disrupted in Parkinson's disease
2009
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Molecular Mechanisms of Hepcidin Regulation: Implications for the Anemia of CKD
2010
ROS Are Good
2016 Standout
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
2009 Standout
Bone Morphogenetic Protein Signaling Is Impaired in an Hfe Knockout Mouse Model of Hemochromatosis
2009
Cellular iron transport
2009
Targeting Hypoxia-Inducible Factors for the Treatment of Anemia in Chronic Kidney Disease Patients
2017 Standout
The Transferrin Receptor Modulates Hfe-Dependent Regulation of Hepcidin Expression
2008
Anemia of Chronic Disease
2005 Standout
Iron Homeostasis and Its Interaction with Prolyl Hydroxylases
2009
Clinical iron deficiency disturbs normal human responses to hypoxia
2016 StandoutNobel
Regulation of hepcidin expression at high altitude
2011
Hepcidin and Disorders of Iron Metabolism
2010
Identification and transcriptome analysis of erythroblastic island macrophages
2019 StandoutNobel
17β-Estradiol Inhibits Iron Hormone Hepcidin Through an Estrogen Responsive Element Half-Site
2012
Regulation of cellular iron metabolism
2011
Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer
2023 StandoutNobel
Adverse Health Consequences of Performance-Enhancing Drugs: An Endocrine Society Scientific Statement
2013 Standout
Hepcidin and iron regulation, 10 years later
2011
Ferroptosis as a target for protection against cardiomyopathy
2019 Standout
Iron-Deficiency Anemia
2015 Standout
Forging a field: the golden age of iron biology
2008
Systemic Iron Homeostasis
2013
Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis
2010
BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expression
2009
The regulation of iron transport
2013
Mitochondrial Iron Metabolism and Its Role in Neurodegeneration
2010
Emerging EPO and EPO receptor regulators and signal transducers
2015
Treatment of erythropoietin deficiency in mice with systemically administered siRNA
2012 StandoutNobel

Works of Juxing Chen being referenced

Transferrin‐Directed Internalization and Cycling of Transferrin Receptor 2
2009
Hereditary hemochromatosis and transferrin receptor 2
2011
The Cytoplasmic Domain of Transferrin Receptor 2 Dictates Its Stability and Response to Holo-transferrin in Hep3B Cells
2007
HFE Modulates Transferrin Receptor 2 Levels in Hepatoma Cells via Interactions That Differ from Transferrin Receptor 1-HFE Interactions
2007
Ferristatin II Promotes Degradation of Transferrin Receptor-1 In Vitro and In Vivo
2013
Abnormal iron uptake and liver cancer
2009
Interaction of the Hereditary Hemochromatosis Protein HFE with Transferrin Receptor 2 Is Required for Transferrin-Induced Hepcidin Expression
2009
Hepatocyte-targeted HFE and TFR2 control hepcidin expression in mice
2010
Transferrin Receptor 2: Evidence for Ligand-induced Stabilization and Redirection to a Recycling Pathway
2006
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