Standout Papers
- Tumor Necrosis Factor: The molecules and Their Emerging Role in Medicine (1992)
Citation Impact
Citing Papers
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility
2003 StandoutNobel
Shortwave infrared fluorescence imaging with the clinically approved near-infrared dye indocyanine green
2018 StandoutNobel
The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency
2008 StandoutScienceNobel
Endotoxin-tolerant Mice Have Mutations in Toll-like Receptor 4 (Tlr4)
1999 Standout
BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C
1997
Big Mitogen-activated Protein Kinase 1 (BMK1) Is a Redox-sensitive Kinase
1996
Characterization of the Structure and Function of a New Mitogen-activated Protein Kinase (p38β)
1996
Development of FRET‐Based Dual‐Excitation Ratiometric Fluorescent pH Probes and Their Photocaged Derivatives
2011
Thienopyrrole-expanded BODIPY as a potential NIR photosensitizer for photodynamic therapy
2013
pH Induced dual “OFF–ON–OFF” switch: influence of a suitably placed carboxylic acid
2012
Correction of the TNF‐LTα‐Deficient Phenotype by Bone Marrow Transplantation
1997
Synthesis of pyrrolyldipyrrinato BF2 complexes by oxidative nucleophilic substitution of boron dipyrromethene with pyrrole
2011
A novel luciferin-based bright chemiluminescent probe for the detection of reactive oxygen species
2009
Unprecedented laser action from energy transfer in multichromophoric BODIPY cassettes
2011
Activation of the Protein Kinase ERK5/BMK1 by Receptor Tyrosine Kinases
1999
Oxidative stress and gene regulation
2000
Long wavelength red fluorescent dyes from 3,5-diiodo-BODIPYs
2010
Water‐Soluble Red‐Emitting Distyryl‐Borondipyrromethene (BODIPY) Dyes for Biolabeling
2012
Development of a pH-activatable fluorescent probe and its application for visualizing cellular pH change
2012
Transition-metal mediated carbon–sulfur bond activation and transformations
2012 Standout
Toll signaling pathways in the innate immune response
2000
c-Src Is Required for Oxidative Stress-mediated Activation of Big Mitogen-activated Protein Kinase 1 (BMK1)
1997
Mice lacking the tumour necrosis factor receptor 1 are resistant to IMF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes
1993 Nature
9-Aryl-1,2-dihydropyrrolo[3,4-b]indolizin-3-one (Seoul-Fluor) as a smart platform for colorful ratiometric fluorescent pH sensors
2011
Far-red to near infrared analyte-responsive fluorescent probes based on organic fluorophore platforms for fluorescence imaging
2012 Standout
Novel far-visible and near-infrared pH probes based on styrylcyanine for imaging intracellular pH in live cells
2012
Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases
1997
Enhancing the Stokes' shift of BODIPY dyes via through-bond energy transfer and its application for Fe3+-detection in live cell imaging
2012
Characterization of the Structure and Function of the Fourth Member of p38 Group Mitogen-activated Protein Kinases, p38δ
1997
Convenient and Efficient FRET Platform Featuring a Rigid Biphenyl Spacer between Rhodamine and BODIPY: Transformation of ‘Turn‐On’ Sensors into Ratiometric Ones with Dual Emission
2011
Energy transfer cassettes based on organic fluorophores: construction and applications in ratiometric sensing
2012
Rational Design, Synthesis, and Spectroscopic and Photophysical Properties of a Visible‐Light‐Excitable, Ratiometric, Fluorescent Near‐Neutral pH Indicator Based on BODIPY
2011
Identification of Substrates and Regulators of the Mitogen-activated Protein Kinase ERK5 Using Chimeric Protein Kinases
1998
The antibacterial arm of the Drosophila innate immune response requires an IκB kinase
2001
Molecular cloning and characterization of a novel member of the MAP kinase superfamily
1999
Crystal structure of the soluble human 55 kd TNF receptor-human TNFβ complex: Implications for TNF receptor activation
1993
Activation Mechanism of the MAP Kinase ERK2 by Dual Phosphorylation
1997
The immune response of Drosophila
2003 StandoutNatureNobel
MAP kinase pathways
1999
The resistance againstListeria monocytogenes and the formation of germinal centers depend on a functional death domain of the 55 kDa tumor necrosis factor receptor
1999
Fluorescent indicators based on BODIPY
2011 Standout
Seeing double: Crystal structures of the type I TNF receptor
1996
Imaging of lysosomal pH changes with a fluorescent sensor containing a novel lysosome-locating group
2012
Relative and absolute determination of fluorescence quantum yields of transparent samples
2013
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
The immune response againstFrancisella tularensislive vaccine strain in Lpsnand Lpsdmice
1996
Cell-mediated cytotoxicity
1993 StandoutNobel
The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death
1994 Standout
Modulating the selectivity of near-IR fluorescent probes toward various metal ions by judicious choice of aqueous buffer solutions
2011
Novel Homologues of CSBP/p38 MAP Kinase: Activation, Substrate Specificity and Sensitivity to Inhibition by Pyridinyl Imidazoles
1997
Synthesis, Spectroscopy, Crystal Structure Determination, and Quantum Chemical Calculations of BODIPY Dyes with Increasing Conformational Restriction and Concomitant Red‐Shifted Visible Absorption and Fluorescence Spectra
2010
Dynamic clicked surfaces based on functionalised pillar[5]arene
2011 StandoutNobel
Highly Photostable Near-Infrared Fluorescent pH Indicators and Sensors Based on BF2-Chelated Tetraarylazadipyrromethene Dyes
2012
Resistance to Salmonellosis in the Chicken Is Linked toNRAMP1and TNC
1997
MEKK3 Directly Regulates MEK5 Activity as Part of the Big Mitogen-activated Protein Kinase 1 (BMK1) Signaling Pathway
1999
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
2003 StandoutNatureNobel
A Tunable Ratiometric pH Sensor Based on Carbon Nanodots for the Quantitative Measurement of the Intracellular pH of Whole Cells
2012
New Insights into the Control of MAP Kinase Pathways
1999
9-Aryl-9-xanthenols: a convenient platform for the design of fluorimetric and colorimetric pH indicators
2012
Synthesis, spectroscopic properties and protein labeling of water soluble 3,5-disubstituted boron dipyrromethenes
2009
Influenza
2018 Nobel
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Synthesis and photophysical properties of new SNARF derivatives as dual emission pH sensors
2011
Through‐Bond Energy Transfer Cassettes with Minimal Spectral Overlap between the Donor Emission and Acceptor Absorption: Coumarin–Rhodamine Dyads with Large Pseudo‐Stokes Shifts and Emission Shifts
2009
Water-solubilisation and bio-conjugation of a red-emitting BODIPY marker
2010
WRM-1 Activates the LIT-1 Protein Kinase to Transduce Anterior/Posterior Polarity Signals in C. elegans
1999 StandoutNobel
A ratiometric near-infrared pH-responsive fluorescent dye based on distyryl BODIPY
2011
Phosphorylation of MAP Kinases by MAP/ERK Involves Multiple Regions of MAP Kinases
1999
New 2,6‐Distyryl‐Substituted BODIPY Isomers: Synthesis, Photophysical Properties, and Theoretical Calculations
2013
Crystallographic Analysis of the Recognition of a Nuclear Localization Signal by the Nuclear Import Factor Karyopherin α
1998 StandoutNobel
Borondipyrromethene-derived Cu2+ sensing chemodosimeter for fast and selective detection
2012
Recent progress in the development of near-infrared fluorescent probes for bioimaging applications
2013 Standout
GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells
1992 Nature
Direct palladium-catalysed C–H arylation of BODIPY dyes at the 3- and 3,5-positions
2012
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Characterization of the Structure and Function of a Novel MAP Kinase Kinase (MKK6)
1996
Triazole-containing BODIPY dyes as novel fluorescent probes for soluble oligomers of amyloid Aβ1–42 peptide
2009
Generalized solvent scales as a tool for investigating solvent dependence of spectroscopic and kinetic parameters. Application to fluorescent BODIPY dyes
2010
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein
2001 StandoutNatureNobel
New insights into the water-solubilisation of fluorophores by post-synthetic “click” and Sonogashira reactions
2012
Fluorescence Switching of Imidazo[1,5-a]pyridinium Ions: pH-Sensors with Dual Emission Pathways
2012
A Fluorogenic Aryl Fluorosulfate for Intraorganellar Transthyretin Imaging in Living Cells and in Caenorhabditis elegans
2015 StandoutNobel
Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation
2000 StandoutNobel
Highly Fluorescent BODIPY Dyes Modulated with Spirofluorene Moieties
2009
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene
1998 StandoutScienceNobel
Oxidative Coupling of 1,7,8-Unsubstituted BODIPYs: Synthesis and Electrochemical and Spectroscopic Properties
2012
Chemistry at Boron: Synthesis and Properties of Red to Near-IR Fluorescent Dyes Based on Boron-Substituted Diisoindolomethene Frameworks
2011
CTLA-4 blockade synergizes with tumor-derived granulocyte– macrophage colony-stimulating factor for treatment of an experimental mammary carcinoma
1998 StandoutNobel
Constitutive Activation of Toll-Mediated Antifungal Defense in Serpin-Deficient Drosophila
1999 StandoutScienceNobel
Induction of pH Sensitivity on the Fluorescence Lifetime of Quantum Dots by NIR Fluorescent Dyes
2012
Cyanine polyene reactivity: scope and biomedical applications
2015
Efficient Fluorescence Resonance Energy Transfer-Based Ratiometric Fluorescent Cellular Imaging Probe for Zn2+ Using a Rhodamine Spirolactam as a Trigger
2010
Water-Soluble BODIPY Derivatives
2009
Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions*
2001 Standout
Anthracene−BODIPY Dyads as Fluorescent Sensors for Biocatalytic Diels−Alder Reactions
2010
Tetrastyryl-Bodipy Dyes: Convenient Synthesis and Characterization of Elusive Near IR Fluorophores
2009
New insights into the solubilization of Bodipy dyes
2009
Structural modification strategies for the rational design of red/NIR region BODIPYs
2014 Standout
Characterization of tumor necrosis factor-deficient mice
1997
Bidirectional Switching of Near IR Emitting Boradiazaindacene Fluorophores
2008
Through-bond energy transfer cassettes based on coumarin–Bodipy/distyryl Bodipy dyads with efficient energy efficiences and large pseudo-Stokes' shifts
2011
Two distinctive pathways for recruitment of naïve and primed IgM+B cells to the gut lamina propria
2005 StandoutNobel
Synthesis of pH-Activatable Red Fluorescent BODIPY Dyes with Distinct Functionalities
2011
Quasi‐One‐Dimensional Electronic Systems Formed from Boron Dipyrromethene (BODIPY) Dyes
2010
The first comparative study of the ability of different hydrophilic groups to water-solubilise fluorescent BODIPY dyes
2013
Water-Soluble Phosphonate-Substituted BODIPY Derivatives with Tunable Emission Channels
2011
Synthesis, spectral and electrochemical properties of phenylated boron-dipyrromethenes
2012
Highly Water-Soluble Neutral BODIPY Dyes with Controllable Fluorescence Quantum Yields
2010
The structure of mitogen-activated protein kinase p38 at 2.1-Å resolution
1997
Distinct Roles of Lymphotoxin α and the Type I Tumor Necrosis Factor (TNF) Receptor in the Establishment of Follicular Dendritic Cells from Non–Bone Marrow–derived Cells
1997
Highly Substituted Bodipy Dyes with Spectroscopic Features Sensitive to the Environment
2011
4,4′-Difluoro-4-bora-3a,4a-diaza-s-indacenes (BODIPYs) as components of novel light active materials
2011
Regioselective Stepwise Bromination of Boron Dipyrromethene (BODIPY) Dyes
2011
Cloning and characterization of mouse extracellular-signal-regulated protein kinase 3 as a unique gene product of 100 kDa
2000
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes
2022 StandoutScienceNobel
An AIE-active hemicyanine fluorogen with stimuli-responsive red/blue emission: extending the pH sensing range by “switch + knob” effect
2012
Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer.
1994 StandoutNobel
New Redox Stable Low Band Gap Conjugated Polymer Based on an EDOT−BODIPY−EDOT Repeat Unit
2009
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
Steric Strain Release-Directed Regioselective Functionalization of meso-Methyl Bodipy Dyes
2011
Fluorescent Sensors for Measuring Metal Ions in Living Systems
2014 Standout
Synthesis and Functionalization of Asymmetrical Benzo-Fused BODIPY Dyes
2010
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
A selective fluorescent sensor for imaging Cu2+ in living cells
2009
Toll-related receptors and the control of antimicrobial peptide expression inDrosophila
2000 StandoutNobel
3,5-Dianilino Substituted Difluoroboron Dipyrromethene: Synthesis, Spectroscopy, Photophysics, Crystal Structure, Electrochemistry, and Quantum-Chemical Calculations
2009
Identification of simple arylfluorosulfates as potent agents against resistant bacteria
2021 StandoutNobel
Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase.
1996
BODIPY dyes in photodynamic therapy
2012 Standout
BODIPY-based sulfoxide: Synthesis, photophysical characterization and response to benzenethiols
2012
Designing Excited States: Theory‐Guided Access to Efficient Photosensitizers for Photodynamic Action
2011
Selective Manipulation of ICT and PET Processes in Styryl-Bodipy Derivatives: Applications in Molecular Logic and Fluorescence Sensing of Metal Ions
2010
Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis
2006 StandoutNobel
Chimeric tumor necrosis factor receptors with constitutive signaling activity.
1995 StandoutNobel
3,5-Diformylboron Dipyrromethenes as Fluorescent pH Sensors
2011
Extracellular Signal-Regulated Kinase 7 (ERK7), a Novel ERK with a C-Terminal Domain That Regulates Its Activity, Its Cellular Localization, and Cell Growth
1999
Single dose of anti–CTLA-4 enhances CD8 + T-cell memory formation, function, and maintenance
2010 StandoutNobel
Constitutive expression of a complement-like protein in Toll and JAK gain-of-function mutants ofDrosophila
2000 StandoutNobel
Convenient synthesis of water-soluble nitrilotriacetic acid (NTA) BODIPY dyes
2010
Role of p38 and JNK Mitogen-Activated Protein Kinases in the Activation of Ternary Complex Factors
1997
Synthesis and spectral properties of novel chlorinated pH fluorescent probes
2010
Reactive Oxygen Species as Mediators of Signal Transduction in Cardiovascular Disease
1998
Versatile synthetic methods for the engineering of thiophene-substituted Bodipy dyes
2009
A Unique Approach to Development of Near-Infrared Fluorescent Sensors for in Vivo Imaging
2012
Rational Design of Ratiometric Near-Infrared Fluorescent pH Probes with Various pKa Values, Based on Aminocyanine
2011
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Revisiting the optical signatures of BODIPY with ab initio tools
2013
Molecular fluorescent probes for monitoring pH changes in living cells
2010
MegaStokes BODIPY-triazoles as environmentally sensitive turn-on fluorescent dyes
2013
A New Half-Condensed Schiff Base Compound: Highly Selective and Sensitive pH-Responsive Fluorescent Sensor
2011
Signal Transduction through MAP Kinase Cascades
1998 Standout
Plant and Animal Sensors of Conserved Microbial Signatures
2010 StandoutScienceNobel
Electrochromism based on the charge transfer process in a ferrocene–BODIPY molecule
2009
Design Strategies for Water-Soluble Small Molecular Chromogenic and Fluorogenic Probes
2013 Standout
PanR1, a Dominant Negative Missense Allele of the Gene Encoding TNF-α (Tnf), Does Not Impair Lymphoid Development
2006 StandoutNobel
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Boron dipyrromethene (BODIPY)-based photosensitizers for photodynamic therapy
2012
Unraveling Function in the TNF Ligand and Receptor Families
1994 StandoutScienceNobel
A Unique Class of Near-Infrared Functional Fluorescent Dyes with Carboxylic-Acid-Modulated Fluorescence ON/OFF Switching: Rational Design, Synthesis, Optical Properties, Theoretical Calculations, and Applications for Fluorescence Imaging in Living Animals
2011
Works of Junyan Han being referenced
A fluorogenic probe for β-galactosidase activity imaging in living cells
2013
3- and 5-Functionalized BODIPYs via the Liebeskind-Srogl reaction
2008
Non-covalent delivery of proteins into mammalian cells
2008
High Level of Neutrophil Extracellular Traps Correlates With Poor Prognosis of Severe Influenza A Infection
2017
Primary Structure of BMK1: A New Mammalian MAP Kinase
1995
In Vitro and In Vivo Photocytotoxicity of Boron Dipyrromethene Derivatives for Photodynamic Therapy
2010
Chemiluminescent Energy‐Transfer Cassettes Based on Fluorescein and Nile Red
2007
Fluorescent Indicators for Intracellular pH
2009
Syntheses and Spectral Properties of Functionalized, Water-Soluble BODIPY Derivatives
2008
Chemiluminescent Energy‐Transfer Cassettes Based on Fluorescein and Nile Red
2007
A Ratiometric pH Reporter For Imaging Protein-dye Conjugates In Living Cells
2009
Tumor Necrosis Factor: The molecules and Their Emerging Role in Medicine
1992 StandoutNobel
Fluorescent Proton Sensors Based on Energy Transfer
2011