Standout Papers
Citation Impact
Citing Papers
Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines
2007 StandoutNobel
Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages
2010 StandoutScience
Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
2011 StandoutScience
Reciprocal T H 17 and Regulatory T Cell Differentiation Mediated by Retinoic Acid
2007 StandoutScience
Sleep Drives Metabolite Clearance from the Adult Brain
2013 StandoutScience
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
IL-4-Induced Selective Clearance of Oligomeric β-Amyloid Peptide1–42 by Rat Primary Type 2 Microglia
2008
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
2011 StandoutNobel
HIF-2α-Haploinsufficient Mice Have Blunted Retinal Neovascularization Due to Impaired Expression of a Proangiogenic Gene Battery
2008
Noradrenaline reduces the ATP-stimulated phosphorylation of p38 MAP kinase via β-adrenergic receptors–cAMP–protein kinase A-dependent mechanism in cultured rat spinal microglia
2009
Inflammation and Alzheimer's disease
2000 Standout
Neuroprotection of microglial conditioned medium on 6‐hydroxydopamine‐induced neuronal death: role of transforming growth factor beta‐2
2009
Amyloid precursor protein‐processing products affect mononuclear phagocyte activation: pathways for sAPP‐ and Aβ‐mediated neurotoxicity
2003
Microglia in organotypic hippocampal slice culture and effects of hypoxia: ultrastructure and lipocortin-1 immunoreactivity
2000
Microglia: active sensor and versatile effector cells in the normal and pathologic brain
2007 Standout
Inflammation and metabolic disorders
2006 StandoutNature
Human and mouse microglia express connexin36, and functional gap junctions are formed between rodent microglia and neurons
2005
Reactive microgliosis
1999
Hypothalamic regulation of sleep and circadian rhythms
2005 StandoutNature
Microglia can be induced by IFN-γ or IL-4 to express neural or dendritic-like markers
2007
The Multifaceted Profile of Activated Microglia
2009
β-adrenoceptor mediated surgery-induced production of pro-inflammatory cytokines in rat microglia cells
2010
Thapsigargin induces microglial transformation from amoeboid to ramified type in vitro
1999
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Descending control of pain
2002 Standout
Dopamine and noradrenaline control distinct functions in rodent microglial cells
2005
Subventricular zone microglia possess a unique capacity for massive in vitro expansion
2008
Asymmetric Disulfonimide‐Catalyzed Synthesis of δ‐Amino‐β‐Ketoester Derivatives by Vinylogous Mukaiyama–Mannich Reactions
2014 StandoutNobel
Astrocyte‐released cytokines induce ramification and outward K+ channel expression in microglia via distinct signalling pathways
2001
Long-Term Proliferation and Dopaminergic Differentiation of Human Mesencephalic Neural Precursor Cells
2001
Enantioselective Total Synthesis and Structure Determination of the Antiherpetic Anthrapyran Antibiotic AH‐1763 IIa
2006
Microglia and neuroprotection: From in vitro studies to therapeutic applications
2010
Brain inflammation and adult neurogenesis: The dual role of microglia
2008
Lipopolysaccharide increases microglial GLT‐1 expression and glutamate uptake capacity in vitro by a mechanism dependent on TNF‐α
2005
β-adrenergic receptor stimulation selectively inhibits IL-12p40 release in microglia11Published on the World Wide Web on 30 March 2001.
2001
Dexamethasone selectively suppresses microglial trophic responses to hippocampal deafferentation
1999
Mechanisms of Microglia-Mediated Neurotoxicity in a New Model of the Stroke Penumbra
2008
Mechanical Effects of Neurofilament Cross-bridges
1996
Adenosine A2A receptor mediates microglial process retraction
2009
Dexamethasone attenuates early expression of three molecules associated with microglia/macrophages activation following rat traumatic brain injury
2007
The G Protein-coupled Receptor CL1 Interacts Directly with Proteins of the Shank Family
2000 StandoutNobel
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
Decoding ALS: from genes to mechanism
2016 StandoutNature
Structural and functional features of central nervous system lymphatic vessels
2015 StandoutNature
Tau phosphorylation: physiological and pathological consequences
2004
Microglia release activators of neuronal proliferation mediated by activation of mitogen‐activated protein kinase, phosphatidylinositol‐3‐kinase/Akt and delta–Notch signalling cascades
2004
Marked induction of inducible nitric oxide synthase and tumor necrosis factor-α in rat CD40+ microglia by comparison to CD40− microglia
2009
Astrocytes Regulate Microglial Phagocytosis of Senile Plaque Cores of Alzheimer's Disease
1998
Neuroprotection of microglia conditioned media from apoptotic death induced by staurosporine and glutamate in cultures of rat cerebellar granule cells
2008
The microenvironment of the tumour–host interface
2001 StandoutNature
The origin and differentiation of microglial cells during development
1998
ATP and adenosine induce ramification of microglia in vitro
2001
P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury
2003 StandoutNature
NG2, a member of chondroitin sulfate proteoglycans family mediates the inflammatory response of activated microglia
2009
Nonlinear elasticity in biological gels
2005 StandoutNature
Microglial cells protect cerebellar granule neurons from apoptosis: Evidence for reciprocal signaling
2001
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
The immunology of stroke: from mechanisms to translation
2011 Standout
Janus faces of microglia in multiple sclerosis
2007
Noradrenaline induces IL-1ra and IL-1 type II receptor expression in primary glial cells and protects against IL-1β-induced neurotoxicity
2009
Combinatorial roles of nuclear receptors in inflammation and immunity
2005
Transient expression of endothelins in the amoeboid microglial cells in the developing rat brain
2006
Alzheimer's Disease
2010 Standout
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
2007 StandoutNatureNobel
Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures
2017
Double dissociations of the effects of amygdala and insular cortex lesions on conditioned taste aversion, passive avoidance, and neophobia in the rat using the excitotoxin ibotenic acid.
1988
Co-culture with astrocytes or microglia protects metabolically impaired neurons
2001
Cataplexy-Active Neurons in the Hypothalamus
2004
Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts
2011
Lipopolysaccharide‐induced down‐regulation of Ca2+release‐activated Ca2+currents (ICRAC) but not Ca2+‐activated TRPM4‐like currents (ICAN) in cultured mouse microglial cells
2007
Traumatic Brain Injury-Induced Hippocampal Neurogenesis Requires Activation of Early Nestin-Expressing Progenitors
2008
Voltage-gated proton currents in microglia of distinct morphology and functional state
1999
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
2005 StandoutNature
Central neuron–glial and glial–glial interactions following axon injury
1998
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Transmitter- and hormone-activated Ca2+ responses in adult microglia/brain macrophages in situ recorded after viral transduction of a recombinant Ca2+ sensor
2011
From bone marrow to microglia: barriers and avenues
2008
System Xc−and Apolipoprotein E Expressed by Microglia Have Opposite Effects on the Neurotoxicity of Amyloid-β Peptide 1–40
2006
A restricted cell population propagates glioblastoma growth after chemotherapy
2012 StandoutNature
Neurotransmitter receptors on microglia
2007
Motility and Ramification of Human Fetal Microglia in Culture: An Investigation Using Time-Lapse Video Microscopy and Image Analysis
2002
Development of microglia in the postnatal rat hippocampus
1998
Microglial-neuronal interactions in synaptic damage and recovery
1999
Reciprocal Interactions Between Microglia and Neurons: From Survival to Neuropathology
2002
Prolyl Hydroxylase Domain Inhibitors: A Route to HIF Activation and Neuroprotection
2009
Thapsigargin induces microglial transformation from amoeboid- to ramified- type in vivo
2000
Can a Ketone Be More Reactive than an Aldehyde? Catalytic Asymmetric Synthesis of Substituted Tetrahydrofurans
2018 StandoutNobel
Activation of Ventrolateral Preoptic Neurons During Sleep
1996 Science
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice
1995 StandoutNature
Enantioselektive Totalsynthese und Strukturaufklärung des antiherpetischen Anthrapyran‐Antibiotikums AH‐1763 IIa
2006
Innervation of Histaminergic Tuberomammillary Neurons by GABAergic and Galaninergic Neurons in the Ventrolateral Preoptic Nucleus of the Rat
1998
Effect of dexamethasone on elevated cytokine mRNA levels in chemical-induced hippocampal injury
1999
Existence of functional β1‐ and β2‐adrenergic receptors on microglia
2002
Specific MicroRNAs Modulate Embryonic Stem Cell–Derived Neurogenesis
2005
Functional role of calcium signals for microglial function
2006
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
INFLAMMATION AND ALZHEIMERS DISEASE
2000
Spatial distribution of calcium channels and cytosolic calcium transients in growth cones and cell bodies of sympathetic neurons.
1988 StandoutNobel
Biological Bases of Childhood Shyness
1988 StandoutScience
Reduced fear expression after lesions of the ventral hippocampus
2002 StandoutNobel
Chemical Anatomy of the Brain
1984 Science
Mucosal Dendritic Cells
2007
Tissue Engineering--Current Challenges and Expanding Opportunities
2002 StandoutScience
Activation of a potassium current by rapid photochemically generated step increases of intracellular calcium in rat sympathetic neurons.
1987 StandoutNobel
Medicinal Plants and Alzheimer's Disease: from Ethnobotany to Phytotherapy
1999
Norepinephrine: A Neuromodulator That Boosts the Function of Multiple Cell Types to Optimize CNS Performance
2012
Potentiation of a Voltage-Gated Proton Current in Acidosis-Induced Swelling of Rat Microglia
2000
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Integrin Signaling
1999 StandoutScience
The mammalian central nervous synaptic cleft contains a high density of periodically organized complexes
2005 StandoutNobel
Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine
2010
Involvement of Stretch-Activated Cl−Channels in Ramification of Murine Microglia
1998
Identification of a Novel Cortactin SH3 Domain-Binding Protein and Its Localization to Growth Cones of Cultured Neurons
1998
The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors.
1990 StandoutNobel
Galanin immunoreactivity in hypothalamic histamine neurons: Further evidence for multiple chemical messengers in the tuberomammillary nucleus
1986
Genetic contributions to generalized arousal of brain and behavior
2003 StandoutNobel
Ischemic Cell Death in Brain Neurons
1999 Standout
Carbon Monoxide: a Putative Neural Messenger
1993 StandoutScience
Rat brain serotonin receptors in Xenopus oocytes are coupled by intracellular calcium to endogenous channels.
1987 StandoutNobel
Synthesis of six-membered oxygenated heterocycles through carbon–oxygen bond-forming reactions
2008
Dual roles of myocardin-related transcription factors in epithelial–mesenchymal transition via slug induction and actin remodeling
2007
Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
2009 StandoutNobel
Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model
2007 StandoutScience
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Regulation of Microglial Development: A Novel Role for Thyroid Hormone
2001
5D4 keratan sulfate epitope identifies a subset of ramified microglia in normal central nervous system parenchyma
1998
Physiology of Microglia
2011 Standout
Works of Junya Tanaka being referenced
Microglial cells prevent nitric oxide-induced neuronal apoptosis in vitro
1998
Two populations of microglial cells isolated from rat primary mixed glial cultures
2003
Fatal Autoimmune Hepatitis Induced by Concurrent Loss of Naturally Arising Regulatory T Cells and PD-1-Mediated Signaling
2008 StandoutNobel
Adrenergic agonists suppress the proliferation of microglia through β2-adrenergic receptor
1998
Expression of CD200 by macrophage-like cells in ischemic core of rat brain after transient middle cerebral artery occlusion
2007
Suppressive effects of phosphodiesterase type IV inhibitors on rat cultured microglial cells: comparison with other types of cAMP-elevating agents
2002
Effects of norepinephrine on rat cultured microglial cells that express α1, α2, β1 and β2 adrenergic receptors
2002
Neurons Induce the Activation of Microglial Cellsin Vitro
1998
Microglial Ramification Requires Nondiffusible Factors Derived from Astrocytes
1996
Overexpression of SOCS3 inhibits astrogliogenesis and promotes maintenance of neural stem cells
2006
NG2 proteoglycan‐expressing microglia as multipotent neural progenitors in normal and pathologic brains
2006
Phosphorylation of neurofilament H subunit as related to arrangement of neurofilaments
1994
Suppression of Stat3 promotes neurogenesis in cultured neural stem cells
2005
Gelsolin is localized in neuronal growth cones
1993
Protective effect of vitamin E against focal brain ischemia and neuronal death through induction of target genes of hypoxia-inducible factor-1
2004
Erythropoietin protects neurons against chemical hypoxia and cerebral ischemic injury by up‐regulating Bcl‐xL expression
2002
l-Serine-mediated release of apolipoprotein E and lipids from microglial cells
2004
Essential role of Peyer's patches in the development of Helicobacter-induced gastritis
2007
Protection of ischemic hippocampal neurons by ginsenoside Rb1, a main ingredient of ginseng root
1997
Morphological differentiation of microglial cells in culture: involvement of insoluble factors derived from astrocytes
1999
Microglia, a potential source of neurons, astrocytes, and oligodendrocytes
2003
Effects of GM-CSF and ordinary supplements on the ramification of microglia in culture: A morphometrical study
1996
Induction of resting microglia in culture medium devoid of glycine and serine
1998
Glucocorticoid- and mineralocorticoid receptors in microglial cells: The two receptors mediate differential effects of corticosteroids
1997
Epidermal Growth Factor Protects Neuronal Cells In Vivo and In Vitro against Transient Forebrain Ischemia- and Free Radical-Induced Injuries
1998
Induction of resting microglia in culture medium devoid of glycine and serine
1998
Evidence for the presence of a histaminergic neuron system in the rat brain: An immunohistochemical analysis
1983
Distribution of the histaminergic neuron system in the central nervous system of rats; a fluorescent immunohistochemical analysis with histidine decar☐ylase as a marker
1984
Accumulation of Macrophage-Like Cells Expressing NG2 Proteoglycan and Iba1 in Ischemic Core of Rat Brain after Transient Middle Cerebral Artery Occlusion
2007
Synthesis of espicufolin based on 6-endo ring closure of o-alkynoylnaphthols †
2001
Rous sarcoma virus-transformed cells develop peculiar adhesive structures along the cell periphery
1993
Apolipoprotein E and Reelin ligands modulate tau phosphorylation through an Apolipoprotein E receptor/disabled‐1/glycogen synthase kinase‐3β cascade
2002
Interleukin 3 Prevents Delayed Neuronal Death in the Hippocampal CA1 Field
1998
Morphological and biochemical analyses of contractile proteins (actin, myosin, caldesmon and tropomyosin) in normal and transformed cells
1993