Citation Impact
Citing Papers
SNARE Function Analyzed in Synaptobrevin/VAMP Knockout Mice
2001 StandoutScienceNobel
[35] Epitope tagging and protein surveillance
1991
An Essential Yeast Gene Encoding a Homolog of Ubiquitin-activating Enzyme
1995
Hallmarks of Cancer: The Next Generation
2011 Standout
The Analysis of New Short-Period Circadian Rhythm Mutants Suggests Features ofD. Melanogaster PeriodGene Function
1992 StandoutNobel
S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein
1990
Regulation of progression through the Gl phase of the cell cycle by the rum1+ gene
1994 StandoutNatureNobel
Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin
1993 StandoutNatureNobel
Homologs of the synaptobrevin/VAMP family of synaptic vesicle proteins function on the late secretory pathway in S. cerevisiae
1993
SNAREs and SNARE regulators in membrane fusion and exocytosis
1999
Cloning of bovine GAP and its interaction with oncogenic ras p21
1988 Nature
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase
1993
The GTPase superfamily: a conserved switch for diverse cell functions
1990 StandoutNature
Fusion tails for the recovery and purification of recombinant proteins
1991
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
A Complex of Cdc4p, Skp1p, and Cdc53p/Cullin Catalyzes Ubiquitination of the Phosphorylated CDK Inhibitor Sic1p
1997
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
1996 StandoutNatureNobel
Sct1 functions in partnership with Cdc10 in a transcription complex that activates cell cycle START and inhibits differentiation
1993
Piezo proteins are pore-forming subunits of mechanically activated channels
2012 StandoutNatureNobel
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
1995 StandoutNature
Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection
1996 Standout
Nuclear targeting of aequorin
1994
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Suppression of c-ras transformation by GTPase-activating protein
1990 Nature
Gene interactions affecting mechanosensory transduction in Caenorhabditis elegans
1994 StandoutNatureNobel
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
1994 StandoutScienceNobel
A protein conjugation system essential for autophagy
1998 StandoutNatureNobel
Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated cdc2 kinase
1993
Determinants of Thrombin Receptor Cleavage. RECEPTOR DOMAINS INVOLVED, SPECIFICITY, AND ROLE OF THE P3 ASPARTATE
1995
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
Involvement of MACH, a Novel MORT1/FADD-Interacting Protease, in Fas/APO-1- and TNF Receptor–Induced Cell Death
1996 Standout
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
A Novel Mechanism for Regulating Activity of a Transcription Factor That Controls the Unfolded Protein Response
1996
Compartmental specificity of cellular membrane fusion encoded in SNARE proteins
2000 StandoutNatureNobel
PAS is a dimerization domain common to Drosophila Period and several transcription factors
1993 StandoutNatureNobel
Heterologous modules for efficient and versatile PCR-based gene targeting inSchizosaccharomyces pombe
1998 Standout
The unfolded-protein-response pathway in yeast
1994
Genetic analysis of mammalian GAP expressed in yeast
1989
Ca2+-dependent and -independent activities of neural and non-neural synaptotagmins
1995 StandoutNatureNobel
Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
1998 Standout
p73 is a human p53-related protein that can induce apoptosis
1997 StandoutNatureNobel
A light-entrainment mechanism for the Drosophila circadian clock
1996 StandoutNatureNobel
Phage antibodies: filamentous phage displaying antibody variable domains
1990 StandoutNatureNobel
Functional and Genomic Analyses Reveal an Essential Coordination between the Unfolded Protein Response and ER-Associated Degradation
2000 Standout
Eph receptors and ephrins in cancer: bidirectional signalling and beyond
2010
Substitution of three amino acids switches receptor specificity of Gqα to that of Giα
1993 StandoutNatureNobel
Signalling from endoplasmic reticulum to nucleus: transcription factor with a basic‐leucine zipper motif is required for the unfolded protein‐response pathway
1996
The syntaxin family of vesicular transport receptors
1993
ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain
1992
Cohesin Rec8 is required for reductional chromosome segregation at meiosis
1999 StandoutNatureNobel
Making antibody fragments using phage display libraries
1991 StandoutNatureNobel
A kinase that responds to stress
1993
Ras-regulated signaling processes in Saccharomyces cerevisiae
1991
The Transmembrane Kinase Ire1p Is a Site-Specific Endonuclease That Initiates mRNA Splicing in the Unfolded Protein Response
1997
Cut2 proteolysis required for sister-chromatid separation in fission yeast
1996 StandoutNatureNobel
Mechanisms of intracellular protein transport
1994 StandoutNatureNobel
Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin
1997 StandoutNatureNobel
The cellular response to unfolded proteins: intercompartmental signaling
1994
The single transmembrane segment of gp210 is sufficient for sorting to the pore membrane domain of the nuclear envelope.
1992 StandoutNobel
A strategy for the generation of conditional mutations by protein destabilization.
1992 StandoutNobel
Dominant yeast and mammalian RAS mutants that interfere with the CDC25-dependent activation of wild-type RAS in Saccharomyces cerevisiae.
1989
Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast.
1996
Antagonist-dependent and -independent steps in the mechanism of adrenergic receptor internalization
1994 StandoutNobel
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Ubiquitin as a degradation signal.
1992
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells
1995 StandoutScienceNobel
The Protein Kinase Complement of the Human Genome
2002 StandoutScience
Binding of the von Hippel-Lindau Tumor Suppressor Protein to Elongin B and C
1995 StandoutScienceNobel
ARD1 and NAT1 proteins form a complex that has N-terminal acetyltransferase activity.
1992 StandoutNobel
Identification of distinct cytoplasmic targets for ras/R-ras and rho regulatory proteins
1989
Purification and characterization of MSH1, a yeast mitochondrial protein that binds to DNA mismatches.
1994
The peptide product of a 5' leader cistron in the beta 2 adrenergic receptor mRNA inhibits receptor synthesis.
1994 StandoutNobel
The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane.
1997
The ras oncogene--an important regulatory element in lower eucaryotic organisms
1989
SNC1, a yeast homolog of the synaptic vesicle-associated membrane protein/synaptobrevin gene family: genetic interactions with the RAS and CAP genes.
1992
Exit from mitosis is regulated by Drosophila fizzy and the sequential destruction of cyclins A, B and B3.
1995
Cell Cycle–Regulated Attachment of the Ubiquitin-Related Protein Sumo to the Yeast Septins
1999 StandoutNobel
A transmembrane protein with a cdc2+CDC28-related kinase activity is required for signaling from the ER to the nucleus
1993
Mouse VAP33 is associated with the endoplasmic reticulum and microtubules
2000 StandoutNobel
The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation.
1992
Structure of the VHL-ElonginC-ElonginB Complex: Implications for VHL Tumor Suppressor Function
1999 StandoutScienceNobel
INTRACELLULAR SIGNALING FROM THE ENDOPLASMIC RETICULUM TO THE NUCLEUS
1998
Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase
1987
Identification and characterization of genes and mutants for an N-terminal acetyltransferase from yeast.
1989
The Distribution and Function of Phosphatidylserine in Cellular Membranes
2010
Viruses in Human Cancers
1991 StandoutScienceNobel
Protein Sorting by Transport Vesicles
1996 StandoutScienceNobel
Xenopus oocyte germinal-vesicle breakdown induced by [Val12]Ras is inhibited by a cytosol-localized Ras mutant.
1989
The yeast Ca(2+)-ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution.
1992
A potential mechanism of "cross-talk" between the p55 tumor necrosis factor receptor and Fas/APO1: proteins binding to the death domains of the two receptors also bind to each other.
1996
Cooperative Interactions Between the Caenorhabditis elegans Homeoproteins UNC-86 and MEC-3
1993 StandoutScienceNobel
The recognition component of the N-end rule pathway.
1990
Human and Drosophila Homeodomain Proteins That Enhance the DNA-Binding Activity of Serum Response Factor
1992 Science
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Sequential Interactions of the TCR with Two Distinct Cytoplasmic Tyrosine Kinases
1994 Science
Association of Human Papillomavirus Types 16 and 18 E6 Proteins with p53
1990 StandoutScience
Protein-Protein Interactions Contributing to the Specificity of Intracellular Vesicular Trafficking
1994 Science
Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus.
1996
Specific Covalent Labeling of Recombinant Protein Molecules Inside Live Cells
1998 StandoutScienceNobel
Monitoring dynamic changes in free Ca2+ concentration in the endoplasmic reticulum of intact cells.
1995
Generation of a Large Combinatorial Library of the Immunoglobulin Repertoire in Phage Lambda
1989 Science
The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway
1987
Thrombin receptor activation. Confirmation of the intramolecular tethered liganding hypothesis and discovery of an alternative intermolecular liganding mode.
1994
Works of Jun‐ichi Nikawa being referenced
Cloning and Sequence of the SCS2 Gene, Which Can Suppress the Defect of IN01 Expression in an Inositol Auxotrophic Mutant of Saccharomyces cerevisiae1
1995
Saccharomyces cerevisiae IRE2/HAC1 is involved in IRE1-mediated KAR2 expression
1996
IRE1 encodes a putative protein kinase containing a membrane‐spanning domain and is required for inositol phototrophy in Saccharomyces cerevisiae
1992
Cloning and Characterization of a p53-related Protein Kinase Expressed in Interleukin-2-activated Cytotoxic T-cells, Epithelial Tumor Cell Lines, and the Testes
2001
Studies of RAS Function in the Yeast Saccharomyces cerevisiae
1988
Erythropoietin‐producing hepatocyte B6 variant‐derived peptides with the ability to induce glioma‐reactive cytotoxic T lymphocytes in human leukocyte antigen‐A2+ glioma patients
2008
Characterization of phosphatidylserine synthase from saccharomyces cerevisiae and a mutant defective in the enzyme
1981
Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae.
1987
Identification of the Upstream Activation Sequences Responsible for the Expression and Regulation of the <italic>PEM1</italic> and <italic>PEM2</italic> Genes Encoding the Enzymes of the Phosphatidylethanolamine Methylation Pathway in <italic>Saccharomyces cerevisiae</italic><xref ref-type="fn" rid="fn1"><sup>1</sup></xref>
1991
The Saccharomyces cerevisiae SCS2 Gene Product, a Homolog of a Synaptobrevin-Associated Protein, Is an Integral Membrane Protein of the Endoplasmic Reticulum and Is Required for Inositol Metabolism
1998
Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method.
1988
Purification of a RAS-Responsive Adenylyl Cyclase Complex from Saccharomyces cerevisiae by Use of an Epitope Addition Method
1988
Rigorous feedback control of cAMP levels in Saccharomyces cerevisiae.
1987
Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae
1987
Cloning and characterization of the high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae.
1986