Citation Impact
Citing Papers
Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
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2003
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2005
The DNA-damage response in human biology and disease
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1996
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Oxyl radicals, redox-sensitive signalling cascades and antioxidants
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1999
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1999 Nobel
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2004
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2003
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1999
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2004
Interaction Codes within the Family of Mammalian Phox and Bem1p Domain-containing Proteins
2003
Chronic Venous Disease
2006 Standout
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2006 Standout
Lipopolysaccharide signaling in endothelial cells
2005
Activation of the Protein Kinase ERK5/BMK1 by Receptor Tyrosine Kinases
1999
Vascular shear stress and activation of inflammatory genes
2006
Oxidative stress and gene regulation
2000
Knockout of ERK5 causes multiple defects in placental and embryonic development
2003
ERK8, a New Member of the Mitogen-activated Protein Kinase Family
2002
CpG motifs in bacterial DNA trigger direct B-cell activation
1995 StandoutNature
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2003
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
2002 StandoutNature
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2002
Toll-like receptor-4 (TLR4) signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors
2003
Identification of Substrates and Regulators of the Mitogen-activated Protein Kinase ERK5 Using Chimeric Protein Kinases
1998
Direct Binding of Activated c-Src to the β3-Adrenergic Receptor Is Required for MAP Kinase Activation
2000 StandoutNobel
Flow-Mediated Signaling Modulates Endothelial Cell Phenotype
2006
Life in extreme environments
2001 StandoutNature
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2001
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2004 Standout
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2004 StandoutNobel
Structural Basis of Protein Kinase C Isoform Function
2008
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
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2002
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2007
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2015
Beyond LDL oxidation: ROS in vascular signal transduction
2003
Genome maintenance mechanisms for preventing cancer
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2004
A clickable inhibitor reveals context-dependent autoactivation of p90 RSK
2007
Activation of c-Raf Kinase by Ultraviolet Light
2002
Inflammation in atherosclerosis
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2001
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2008
Reactive oxygen species have a causal role in multiple forms of insulin resistance
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1998
Klf2 Is an Essential Regulator of Vascular Hemodynamic Forces In Vivo
2006
Sensors and regulators of intracellular pH
2009 Standout
JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species
2005
eNOS Activation by Physical Forces: From Short-Term Regulation of Contraction to Chronic Remodeling of Cardiovascular Tissues
2009
Points of control in inflammation
2002 StandoutNature
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2005 Standout
Human JIK, a Novel Member of the STE20 Kinase Family That Inhibits JNK and Is Negatively Regulated by Epidermal Growth Factor
1999
Coronary endothelium expresses a pathologic gene pattern compared to aortic endothelium: Correlation of asynchronous hemodynamics and pathology in vivo
2006
Expression and subcellular distribution of the active form of c-Src tyrosine kinase in differentiating human endometrial stromal cells
2002
The Role of Shear Stress in Atherosclerosis: Action Through Gene Expression and Inflammation?
2004
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Gene inhibition using antisense oligodeoxynucleotides
1994 Nature
Regulation of endothelial barrier function during flow-induced conversion to an arterial phenotype
2007 StandoutNobel
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Src and Cas Are Essentially but Differentially Involved in Angiotensin II-Stimulated Migration of Vascular Smooth Muscle Cells via Extracellular Signal-Regulated Kinase 1/2 and c-Jun NH2-Terminal Kinase Activation
2004
Oxidative Stress-induced Phospholipase C-γ1 Activation Enhances Cell Survival
2001
Differential regulation of HIF-1α prolyl-4-hydroxylase genes by hypoxia in human cardiovascular cells
2003
The Role of Hydrogen Peroxide in Endothelial Proliferative Responses
2002
The MAP kinase ERK5 binds to and phosphorylates p90 RSK
2006
Interleukin-6-induced JAK2/STAT3 signaling pathway in endothelial cells is suppressed by hemodynamic flow
2004
Signaling Mechanisms Regulating Endothelial Permeability
2005
Mechanisms of Cell Death in Oxidative Stress
2006
Endothelial Protein Kinase C Isoform Identity and Differential Activity of PKCζ in an Athero-Susceptible Region of Porcine Aorta
2005
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Angiogenesis Inhibitors Endostatin or TNP-470 Reduce Intimal Neovascularization and Plaque Growth in Apolipoprotein E–Deficient Mice
1999
Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase Nox1
2001
ERK and p38 MAPK-Activated Protein Kinases: a Family of Protein Kinases with Diverse Biological Functions
2004 Standout
Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects
2002
H2O2-dependent Activation of GCLC-ARE4 Reporter Occurs by Mitogen-activated Protein Kinase Pathways without Oxidation of Cellular Glutathione or Thioredoxin-1
2004
Hydrogen Peroxide Stimulates c-Src-mediated Big Mitogen-activated Protein Kinase 1 (BMK1) and the MEF2C Signaling Pathway in PC12 Cells
2002
H 2 O 2 , a Necessary Evil for Cell Signaling
2006 StandoutScience
Chronic Physiological Shear Stress Inhibits Tumor Necrosis Factor–Induced Proinflammatory Responses in Rabbit Aorta Perfused Ex Vivo
2003
Selective activation of Src family kinases and JNK by low levels of chromium(VI)
2003
Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions*
2001 Standout
Chemical Glycobiology
2001 StandoutScienceNobel
MAP Kinases
2001
ATG Systems from the Protein Structural Point of View
2009 StandoutNobel
Reactive oxygen species in cell signaling
2000 Standout
KLF2 Primes the Antioxidant Transcription Factor Nrf2 for Activation in Endothelial Cells
2008
Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature
2004
Big Mitogen-Activated Protein Kinase (BMK1)/ERK5 Protects Endothelial Cells From Apoptosis
2003
International Union of Pharmacology. XXIII. The Angiotensin II Receptors
2000 Standout
Early Allelic Selection in Maize as Revealed by Ancient DNA
2003 StandoutScienceNobel
Aldolase Antibodies of Remarkable Scope
1998 StandoutNobel
Chronic venous disease.
2007
Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline
2014 Standout
Fluid shear stress stimulates phosphorylation-dependent nuclear export of HDAC5 and mediates expression of KLF2 and eNOS
2009
Frontiers in Interventional Cardiology
1998
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Broken Limits to Life Expectancy
2002 StandoutScience
Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases
2002 StandoutScience
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
2005 StandoutNobel
Ang II–Stimulated Superoxide Production Is Mediated via Phospholipase D in Human Vascular Smooth Muscle Cells
1999
The Regulation of Reactive Oxygen Species Production during Programmed Cell Death
1998
Biomechanical Forces in Atherosclerosis-Resistant Vascular Regions Regulate Endothelial Redox Balance via Phosphoinositol 3-Kinase/Akt-Dependent Activation of Nrf2
2007
Increased Endothelial Mitogen-Activated Protein Kinase Phosphatase-1 Expression Suppresses Proinflammatory Activation at Sites That Are Resistant to Atherosclerosis
2008
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Effects of Amylopectin Branch Chain Length and Amylose Content on the Gelatinization and Pasting Properties of Starch
1999
Atheroprotective Signaling Mechanisms Activated by Steady Laminar Flow in Endothelial Cells
2008
Fmoc-Based Synthesis of Peptide-αThioesters: Application to the Total Chemical Synthesis of a Glycoprotein by Native Chemical Ligation
1999 StandoutNobel
Extracellular Signal-Regulated Kinase 7 (ERK7), a Novel ERK with a C-Terminal Domain That Regulates Its Activity, Its Cellular Localization, and Cell Growth
1999
Subcellular targeting of oxidants during endothelial cell migration
2005
Enzyme-catalyzed synthesis of carbohydrates
1989
Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis
2016 Standout
Arsenic carcinogenicity: Relevance of c-Src activation
2002
Rapid Phosphorylation of Heterogeneous Nuclear Ribonucleoprotein C1/C2 in Response to Physiologic Levels of Hydrogen Peroxide in Human Endothelial Cells
2002
Elucidation of Molecular Events Leading to Neutrophil Apoptosis following Phagocytosis
2003
Subcellular Localization and Biological Actions of Activated RSK1 Are Determined by Its Interactions with Subunits of Cyclic AMP-Dependent Protein Kinase
2006
Induction of Endothelial NO Synthase by Hydrogen Peroxide via a Ca 2+ /Calmodulin-Dependent Protein Kinase II/Janus Kinase 2–Dependent Pathway
2001
Interactions of Oxidants With Vascular Signaling Systems
2000
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Urokinase Receptor and Fibronectin Regulate the ERKMAPK to p38MAPK Activity Ratios That Determine Carcinoma Cell Proliferation or Dormancy In Vivo
2001
Modulation of Protein Kinase Activity and Gene Expression by Reactive Oxygen Species and Their Role in Vascular Physiology and Pathophysiology
2000
Recent Advances in the Chemoenzymatic Synthesis of Carbohydrates and Carbohydrate Mimetics
1996
A Catalytic Enantioselective Route to Hydroxy-Substituted Quaternary Carbon Centers: Resolution of Tertiary Aldols with a Catalytic Antibody
1999 StandoutNobel
Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives
2011 Standout
KLF2 Is a Novel Transcriptional Regulator of Endothelial Proinflammatory Activation
2004
Hydrogen Peroxide as a Paracrine Vascular Mediator: Regulation and Signaling Leading to Dysfunction
2006
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor
1999 Standout
The Reactive Adventitia
2002
Angiotensin II Induces Migration and Pyk2/Paxillin Phosphorylation of Human Monocytes
2001
Works of Jun‐ichi Abe being referenced
Cardiac mitochondrial connexin 43 regulates apoptosis
2006
c-Src Is Required for Oxidative Stress-mediated Activation of Big Mitogen-activated Protein Kinase 1 (BMK1)
1997
Suppression of Neointimal Smooth Muscle Cell Accumulation in Vivo by Antisense cdc2 and cdk2 Oligonucleotides in Rat Carotid Artery
1994
Crystal and Molecular Structure of Barley α-Amylase
1994
1,25-Dihydroxyvitamin D3 upregulates the phosphatidylinositol signaling pathway in human keratinocytes by increasing phospholipase C levels.
1995
Mitochondrial Dok-4 Recruits Src Kinase and Regulates NF-κB Activation in Endothelial Cells
2005
Molecular Cloning of Mouse ERK5/BMK1 Splice Variants and Characterization of ERK5 Functional Domains
2001
Reactive Oxygen Species Activate p90 Ribosomal S6 Kinase via Fyn and Ras
2000
Stress and Vascular Responses: Atheroprotective Effect of Laminar Fluid Shear Stress in Endothelial Cells: Possible Role of Mitogen-Activated Protein Kinases
2003
14-3-3 Binding to Na+/H+ Exchanger Isoform-1 Is Associated with Serum-dependent Activation of Na+/H+ Exchange
2001
Pleckstrin Homology and Phosphotyrosine-binding Domain-dependent Membrane Association and Tyrosine Phosphorylation of Dok-4, an Inhibitory Adapter Molecule Expressed in Epithelial Cells
2004
Differential Role of MEK5α and MEK5β in BMK1/ERK5 Activation
2004
Fyn and JAK2 Mediate Ras Activation by Reactive Oxygen Species
1999
Src and Cas Mediate JNK Activation but Not ERK1/2 and p38 Kinases by Reactive Oxygen Species
2000
Endothelial Atheroprotective and Anti‐inflammatory Mechanisms
2001
A periodic distribution of the chain length of amylopectin as revealed by high-performance anion-exchange chromatography
1996
Current Status and Challenges in Jcog Data Center (DC) And Operations Office (OPS)
2012
Inhibition of Tumor Necrosis Factor-α–Induced SHP-2 Phosphatase Activity by Shear Stress
2003
p38 Kinase Is a Negative Regulator of Angiotensin II Signal Transduction in Vascular Smooth Muscle Cells
1998
A fumagillin derivative angiogenesis inhibitor, AGM-1470, inhibits activation of cyclin-dependent kinases and phosphorylation of retinoblastoma gene product but not protein tyrosyl phosphorylation or protooncogene expression in vascular endothelial cells.
1994
Synthesis of branched cyclomalto-oligosaccharides using Pseudomonas isoamylase
1986
Inhibiting p90 Ribosomal S6 Kinase Prevents Na + -H + Exchanger–Mediated Cardiac Ischemia-Reperfusion Injury
2006
Adenovirus-Mediated Overexpression of Diacylglycerol Kinase-ζ Inhibits Endothelin-1–Induced Cardiomyocyte Hypertrophy
2005
Angiotensin II Stimulates p90 rsk in Vascular Smooth Muscle Cells
1997
Role of p90 Ribosomal S6 Kinase–Mediated Prorenin-Converting Enzyme in Ischemic and Diabetic Myocardium
2006
Flow Antagonizes TNF-α Signaling in Endothelial Cells by Inhibiting Caspase-Dependent PKCζ Processing
2007
Cardiac-Specific Overexpression of Diacylglycerol Kinase ζ Prevents Gq Protein-Coupled Receptor Agonist-Induced Cardiac Hypertrophy in Transgenic Mice
2005
Extracellular Signal-Regulated Kinase 5 SUMOylation Antagonizes Shear Stress–Induced Antiinflammatory Response and Endothelial Nitric Oxide Synthase Expression in Endothelial Cells
2008
Stimulated Activation of Platelet-Derived Growth Factor Receptor In Vivo in Balloon-Injured Arteries
1997
Cyclophilin A Mediates Vascular Remodeling by Promoting Inflammation and Vascular Smooth Muscle Cell Proliferation
2008
Novel Mechanisms of Endothelial Mechanotransduction
2014
Differential Regulation of p90 Ribosomal S6 Kinase and Big Mitogen–Activated Protein Kinase 1 by Ischemia/Reperfusion and Oxidative Stress in Perfused Guinea Pig Hearts
1999
Identification of Activators of ERK5 Transcriptional Activity by High-Throughput Screening and the Role of Endothelial ERK5 in Vasoprotective Effects Induced by Statins and Antimalarial Agents
2014
Reactive Oxygen Species as Mediators of Signal Transduction in Cardiovascular Disease
1998
Fluid Shear Stress Activates Proline-Rich Tyrosine Kinase via Reactive Oxygen Species–Dependent Pathway
2002
The Hinge-Helix 1 Region of Peroxisome Proliferator-Activated Receptor γ1 (PPARγ1) Mediates Interaction with Extracellular Signal-Regulated Kinase 5 and PPARγ1 Transcriptional Activation: Involvement in Flow-Induced PPARγ Activation in Endothelial Cells
2004