Citation Impact
Citing Papers
The Caenorhabditis elegans vulval morphogenesis gene sqv - 4 encodes a UDP-glucose dehydrogenase that is temporally and spatially regulated
2002 StandoutNobel
A small-molecule switch for Golgi sulfotransferases
2004 StandoutNobel
Nascent RNA Sequencing Reveals Widespread Pausing and Divergent Initiation at Human Promoters
2008 StandoutScience
1 Developmental roles and clinical significance of Hedgehog signaling
2003
Mice deficient in Ext2 lack heparan sulfate and develop exostoses
2005
Abrogation of heparan sulfate synthesis inDrosophiladisrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways
2004
The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate
2000
A Visualizable Chain‐Terminating Inhibitor of Glycosaminoglycan Biosynthesis in Developing Zebrafish
2014 StandoutNobel
Shaping Morphogen Gradients by Proteoglycans
2009
Disruption of Gastrulation and Heparan Sulfate Biosynthesis in EXT1-Deficient Mice
2000
Heparin-Protein Interactions
2002 Standout
The link between heparan sulfate and hereditary bone disease: finding a function for the EXT family of putative tumor suppressor proteins
2001
An Abundance of Bidirectional Promoters in the Human Genome
2004
Hedgehog: functions and mechanisms
2008 Standout
The mechanisms of Hedgehog signalling and its roles in development and disease
2013 Standout
Psoriasis
2009 Standout
Cloning and characterization of a novel bicoid-related homeobox transcription factor gene, RIEG, involved in Rieger syndrome
1996 Standout
The Stem Region of the Sulfotransferase GlcNAc6ST-1 Is a Determinant of Substrate Specificity
2004 StandoutNobel
Hedgehog Movement Is Regulated through tout velu–Dependent Synthesis of a Heparan Sulfate Proteoglycan
1999
Pathogenesis and clinical features of psoriasis
2007 Standout
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca2+ release channel
2007 StandoutNobel
Functional analysis of secreted and transmembrane proteins critical to mouse development
2001
Role of platelet-derived growth factors in physiology and medicine
2008 Standout
Heparan sulphate proteoglycans: the sweet side of development
2005
Antigen presentation in the thymus for positive selection and central tolerance induction
2009
Glycosylation in Cellular Mechanisms of Health and Disease
2006 Standout
Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion
1998 Nature
Heparan sulfate proteoglycan modulation of developmental signaling in Drosophila
2002
The Hedgehog and Wnt signalling pathways in cancer
2001 StandoutNature
The roles of enzyme localisation and complex formation in glycan assembly within the Golgi apparatus
2004 StandoutNobel
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Psoriasis
2015 Standout
The EXT2 multiple exostoses gene defines a family of putative tumour suppressor genes
1996
Identification and characterization of two novel brain-derived immunoglobulin superfamily members with a unique structural organization
2004
Myocardial Substrate Metabolism in the Normal and Failing Heart
2005 Standout
Unraveling the therapeutic potential of the Hedgehog pathway in cancer
2013 Standout
Maternal Wnt11 Activates the Canonical Wnt Signaling Pathway Required for Axis Formation in Xenopus Embryos
2005
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
2002 StandoutNobel
Genetics of morphogen gradients
2001
Hedgehog signaling in animal development: paradigms and principles
2001 Standout
Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases
2018 Standout
Wnt/β-Catenin Signaling in Development and Disease
2006 Standout
Mechanisms of Hedgehog gradient formation and interpretation
2005
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate
1998
Efflux-dependent auxin gradients establish the apical–basal axis of Arabidopsis
2003 StandoutNature
Identification of a Major Susceptibility Locus on Chromosome 6p and Evidence for Further Disease Loci Revealed by a Two Stage Genome-Wide Search in Psoriasis
1997
Ext1-Dependent Heparan Sulfate Regulates the Range of Ihh Signaling during Endochondral Ossification
2004
A Novel Paradigm for Heart Failure With Preserved Ejection Fraction
2013 Standout
Golgi Localization of Carbohydrate Sulfotransferases Is a Determinant of L-selectin Ligand Biosynthesis
2003 StandoutNobel
Functional binding of secreted molecules to heparan sulfate proteoglycans in Drosophila
2000
Cell cycle–regulated phosphorylation of p220NPATby cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription
2000
Inflammation in Atherosclerosis
2009 Standout
The Putative Tumor Suppressors EXT1 and EXT2 Are Glycosyltransferases Required for the Biosynthesis of Heparan Sulfate
1998
Regulation of cardiac hypertrophy by intracellular signalling pathways
2006 Standout
Interpreting cDNA sequences: Some insights from studies on translation
1996
Evidence for an Expansion-Based Temporal Shh Gradient in Specifying Vertebrate Digit Identities
2004 Standout
The Orc4p and Orc5p Subunits of the Xenopus and Human Origin Recognition Complex Are Related to Orc1p and Cdc6p
1998 StandoutNobel
MDGAs interact selectively with neuroligin-2 but not other neuroligins to regulate inhibitory synapse development
2012 StandoutNobel
The EXT1/EXT2 tumor suppressors: catalytic activities and role in heparan sulfate biosynthesis
2000
Fibrosis, not cell size, delineates β-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivo
2006 StandoutNobel
A Novel Angiotensin-Converting Enzyme–Related Carboxypeptidase (ACE2) Converts Angiotensin I to Angiotensin 1-9
2000 Standout
The mouse and human genes encoding the recognition component of the N-end rule pathway
1998 StandoutNobel
In Vivo Imaging of Membrane-Associated Glycans in Developing Zebrafish
2008 StandoutScienceNobel
Arterial Stiffness and Cardiovascular Events
2010 Standout
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
2002 StandoutNobel
The Molecular Diversity of Glycosaminoglycans Shapes Animal Development
2006
The SQV-1 UDP-glucuronic acid decarboxylase and the SQV-7 nucleotide-sugar transporter may act in the Golgi apparatus to affect Caenorhabditis elegans vulval morphogenesis and embryonic development
2002 StandoutNobel
Adrenomedullin gene expression differences in mice do not affect blood pressure but modulate hypertension-induced pathology in males
2007 StandoutNobel
Gene Regulatory Networks and the Evolution of Animal Body Plans
2006 StandoutScience
SQV-7, a protein involved in Caenorhabditis elegans epithelial invagination and early embryogenesis, transports UDP-glucuronic acid, UDP- N - acetylgalactosamine, and UDP-galactose
2001 StandoutNobel
Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene
2004 StandoutNobel
Differential myocardial gene expression in the development and rescue of murine heart failure
2003
Order Out of Chaos: Assembly of Ligand Binding Sites in Heparan Sulfate
2002
Nix-Mediated Apoptosis Links Myocardial Fibrosis, Cardiac Remodeling, and Hypertrophy Decompensation
2008
Cerebellar proteoglycans regulate sonic hedgehog responses during development
2002
Distinct and collaborative roles ofDrosophilaEXT family proteins in morphogen signalling and gradient formation
2004
The gene expression fingerprint of human heart failure
2002
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response
2009 StandoutNobel
Functions of Cell Surface Heparan Sulfate Proteoglycans
1999 Standout
Mechanisms in Protein O-Glycan Biosynthesis and Clinical and Molecular Aspects of Protein O-Glycan Biosynthesis Defects: A Review
2006
Regulatory Principles of Developmental Signaling
2002 StandoutNobel
Enchondromatosis: insights on the different subtypes.
2010
Biomarkers of Cardiovascular Disease
2006
Cyclin-Dependent Kinase-9
2004
The Dendritic Cell Lineage: Ontogeny and Function of Dendritic Cells and Their Subsets in the Steady State and the Inflamed Setting
2013 Standout
Works of Jung Ahn being referenced
Identification of novel mutations in the human EXT1 tumor suppressor gene
1997
Peaks of Linkage Are Localized by a BAC/PAC Contig of the 6p Reading Disability Locus
2001
Cloning of the putative tumour suppressor gene for hereditary multiple exostoses (EXT1)
1995
The genomic organization of the histone clusters on human 6p21.3
1999
Cloning of a Novel MHC-Encoded Serine Peptidase Highly Expressed by Cortical Epithelial Cells of the Thymus
1999