Citation Impact
Citing Papers
Rapid and automated design of two-component protein nanomaterials using ProteinMPNN
2024 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
β-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation
2009 StandoutNobel
Stable interaction between α5β1 integrin and Tie2 tyrosine kinase receptor regulates endothelial cell response to Ang-1
2005
Chapter 2 PI3K/PTEN Signaling in Angiogenesis and Tumorigenesis
2009
Angiopoietin-1 modulates endothelial cell function and gene expression via the transcription factor FKHR (FOXO1)
2004
Reduced maternal expression of adrenomedullin disrupts fertility, placentation, and fetal growth in mice
2006 StandoutNobel
Pericytes are required for blood–brain barrier integrity during embryogenesis
2010 StandoutNature
Differential function of Tie2 at cell–cell contacts and cell–substratum contacts regulated by angiopoietin-1
2008
The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis
2005 StandoutNobel
mTOR Signaling in Growth Control and Disease
2012 Standout
Self-Renewing Osteoprogenitors in Bone Marrow Sinusoids Can Organize a Hematopoietic Microenvironment
2007 Standout
AKT/PKB Signaling: Navigating Downstream
2007 Standout
The Role of Angiopoietin-Like Proteins in Angiogenesis and Metabolism
2008
Pathogenesis and clinical features of psoriasis
2007 Standout
Molecular mechanisms of blood vessel growth
2001
The dual role of thymidine phosphorylase in cancer development and chemotherapy
2009
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
New model of tumor angiogenesis: dynamic balance between vessel regression and growth mediated by angiopoietins and VEGF
1999
Angiopoietins assemble distinct Tie2 signalling complexes in endothelial cell–cell and cell–matrix contacts
2008
Apoptosis in the vasculature: mechanisms and functional importance
2000
Lymphangiogenesis: Molecular Mechanisms and Future Promise
2010 Standout
The phosphatidylinositol 3-Kinase–AKT pathway in human cancer
2002 Standout
Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
2010 Standout
Altered Expression of Angiopoietins and Tie2 Endothelium Receptor in Psoriasis
2001
Glypican-1 modulates the angiogenic and metastatic potential of human and mouse cancer cells
2008
Tie2/Angiopoietin-1 Signaling Regulates Hematopoietic Stem Cell Quiescence in the Bone Marrow Niche
2004 Standout
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Deletion of the Carboxyl Terminus of Tie2 Enhances Kinase Activity, Signaling, and Function
2002
Increased angiopoietin2 expression is associated with endothelial apoptosis and blood–brain barrier breakdown
2005
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Evolving functions of endothelial cells in inflammation
2007
Signaling and regulation of endothelial cell survival by angiopoietin-2
2006
Lymphangiogenesis in development and human disease
2005 StandoutNature
A designed angiopoietin-2 variant, pentameric COMP-Ang2, strongly activates Tie2 receptor and stimulates angiogenesis
2009
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Thrombin promotes pericyte coverage by Tie2 activation in a rat model of intracerebral hemorrhage
2018
Integrin α5β1-Ang1/Tie2 receptor cross-talk regulates brain endothelial cell responses following cerebral ischemia
2018
Oligomerization and Multimerization Are Critical for Angiopoietin-1 to Bind and Phosphorylate Tie2
2005
Regulation of angiogenesis by hypoxia: role of the HIF system
2003 StandoutNobel
SLAM Family Receptors Distinguish Hematopoietic Stem and Progenitor Cells and Reveal Endothelial Niches for Stem Cells
2005 Standout
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
2010 StandoutNature
Paclitaxel plus Bevacizumab versus Paclitaxel Alone for Metastatic Breast Cancer
2007 Standout
Circulating Endothelial Progenitor Cells, Vascular Function, and Cardiovascular Risk
2003 Standout
Vascular-specific growth factors and blood vessel formation
2000 StandoutNature
Targeting Tie2 for Treatment of Diabetic Retinopathy and Diabetic Macular Edema
2016
HMG-CoA reductase inhibitor mobilizes bone marrow–derived endothelial progenitor cells
2001
Origin and physiological roles of inflammation
2008 StandoutNature
Therapeutic targeting of the angiopoietin–TIE pathway
2017
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
AKT/PKB Signaling: Navigating the Network
2017 Standout
Targeting the ANGPT–TIE2 pathway in malignancy
2010
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Adrenomedullin induces lymphangiogenesis and ameliorates secondary lymphoedema
2008
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease
2004
Control of vascular morphogenesis and homeostasis through the angiopoietin–Tie system
2009
Angiopoietin-1-induced angiogenesis is modulated by endothelial NADPH oxidase
2006
Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans
2009 StandoutNobel
Ablation in Mice of the mTORC Components raptor, rictor, or mLST8 Reveals that mTORC2 Is Required for Signaling to Akt-FOXO and PKCα, but Not S6K1
2006
Receptor Activity-modifying Proteins 2 and 3 Have Distinct Physiological Functions from Embryogenesis to Old Age
2007 StandoutNobel
Possible Mechanisms of Acquired Resistance to Anti-angiogenic Drugs: Implications for the Use of Combination Therapy Approaches
2001
Angiogenesis as a therapeutic target
2005 StandoutNature
Expression of the angiopoietins and their receptor Tie2 in human renal clear cell carcinomas; regulation by the von Hippel‐Lindau gene and hypoxia
2002
Adrenomedullin signaling is necessary for murine lymphatic vascular development
2007
Angiopoietin-1 promotes LYVE-1-positive lymphatic vessel formation
2005
COMP-Ang1: A designed angiopoietin-1 variant with nonleaky angiogenic activity
2004
HMG-CoA reductase inhibitor mobilizes bone marrow–derived endothelial progenitor cells
2001
VEGF-Induced BBB Permeability is Associated with an MMP-9 Activity Increase in Cerebral ischemia: Both Effects Decreased by ANG-1
2005
Role of Akt Signaling in Vascular Homeostasis and Angiogenesis
2002
Magnesium in Man: Implications for Health and Disease
2014 Standout
PTEN Activity Is Modulated During Ischemia and Reperfusion
2005 StandoutNobel
Adrenomedullin gene expression differences in mice do not affect blood pressure but modulate hypertension-induced pathology in males
2007 StandoutNobel
Opposing actions of angiopoietin-2 on Tie2 signaling and FOXO1 activation
2016
Hydrops Fetalis, Cardiovascular Defects, and Embryonic Lethality in Mice Lacking the Calcitonin Receptor-Like Receptor Gene
2006 StandoutNobel
Angiopoietin-1 promotes lymphatic sprouting and hyperplasia
2005
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Akt-Dependent Phosphorylation of p21Cip1 Regulates PCNA Binding and Proliferation of Endothelial Cells
2001
Microvascular patterning is controlled by fine-tuning the Akt signal
2004
Adrenomedullin and CGRP interact with endogenous calcitonin-receptor-like receptor in endothelial cells and induce its desensitisation by different mechanisms
2006
Angiopoietin‐1‐induced phosphatidyl‐inositol 3‐kinase activation prevents neuronal apoptosis
2003
F‐domain valency determines outcome of signaling through the angiopoietin pathway
2021 StandoutNobel
Angiopoietin-1/Tie2 receptor signaling in vascular quiescence and angiogenesis.
2010
Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure
2011 Standout
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization
2010 Standout
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
A role for survivin in chemoresistance of endothelial cells mediated by VEGF
2002
Coexistence of Quiescent and Active Adult Stem Cells in Mammals
2010 StandoutScience
Signaling and Functions of Angiopoietin-1 in Vascular Protection
2006
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates
2014
Obligatory participation of macrophages in an angiopoietin 2-mediated cell death switch
2007
Works of June-No So being referenced
Molecular cloning and characterization of a novel angiopoietin family protein, angiopoietin‐3
1999
Vascular endothelial growth factor increases the intracellular magnesium
2006
Angiopoietin‐1 negatively regulates expression and activity of tissue factor in endothelial cells
2001
Angiopoietin-1 Induces Endothelial Cell Sprouting Through the Activation of Focal Adhesion Kinase and Plasmin Secretion
2000
Angiopoietin‐1 is an apoptosis survival factor for endothelial cells
1999
Angiogenic role of adrenomedullin through activation of Akt, mitogen‐activated protein kinase, and focal adhesion kinase in endothelial cells
2003
Angiopoietin-1 Regulates Endothelial Cell Survival Through the Phosphatidylinositol 3′-Kinase/Akt Signal Transduction Pathway
2000