Standout Papers
Citation Impact
Citing Papers
Fast molecular tracking maps nanoscale dynamics of plasma membrane lipids
2010 StandoutNobel
Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
2000 StandoutNature
Redistribution of Silencing Proteins from Telomeres to the Nucleolus Is Associated with Extension of Life Span in S. cerevisiae
1997
The DNA-damage response in human biology and disease
2009 StandoutNature
Human RecQ5beta, a large isomer of RecQ5 DNA helicase, localizes in the nucleoplasm and interacts with topoisomerases 3alpha and 3beta
2000
The role of DNA damage and repair in aging through the prism of Koch-like criteria
2012
Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity
2001
Exonuclease X of Escherichia coli
1999
Replication Protein A Physically Interacts with the Bloom's Syndrome Protein and Stimulates Its Helicase Activity
2000
Do Changes in Chromosomes Cause Aging?
1996
The Werner syndrome protein is a DNA helicase
1997
Werner syndrome exonuclease catalyzes structure-dependent degradation of DNA
2000
Mapping of a Major Locus that Determines Telomere Length in Humans
2004
Mobile D-loops are a preferred substrate for the Bloom's syndrome helicase
2006
rqh1+, a fission yeast gene related to the Bloom's and Werner's syndrome genes, is required for reversible S phase arrest
1997
Cellular senescence and organismal aging
2008
The Bloom's Syndrome Protein (BLM) Interacts with MLH1 but Is Not Required for DNA Mismatch Repair
2001
The Exonucleolytic and Endonucleolytic Cleavage Activities of Human Exonuclease 1 Are Stimulated by an Interaction with the Carboxyl-terminal Region of the Werner Syndrome Protein
2003
Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1
2001
Reprogramming aging and progeria
2012
Protein Oxidation in Aging, Disease, and Oxidative Stress
1997 Standout
Interaction between yeast Sgs1 helicase and DNA topoisomerase III
2000
Mutation of the mouse klotho gene leads to a syndrome resembling ageing
1997 StandoutNature
The Involvement of DNA-Damage and -Repair Defects in Neurological Dysfunction
2008
Potential Role for the BLM Helicase in Recombinational Repair via a Conserved Interaction with RAD51
2001
Obstructive sleep apnea and hypertrophic cardiomyopathy: A common and potential harmful combination
2012
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Rapid accumulation of genome rearrangements in liver but not in brain of old mice
1997
Stimulation of Flap Endonuclease-1 by the Bloom's Syndrome Protein
2004
Structure and Expression of the TREX1 and TREX2 3′→5′ Exonuclease Genes
2001
The angiotensin‐converting enzyme (ACE) genetic polymorphism: its relationship with plasma ACE level and myocardial infarction
1994
Biochemical characterization of the RECQ4 protein, mutated in Rothmund-Thomson syndrome
2005
The Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalpha
2002
RecQ helicase, in concert with RecA and SSB proteins, initiates and disrupts DNA recombination
1998
RecQ and RecJ process blocked replication forks prior to the resumption of replication in UV-irradiated Escherichia coli
1999
The Werner Syndrome Gene Product Co-purifies with the DNA Replication Complex and Interacts with PCNA and Topoisomerase I
1999
RecQ Helicase and Topoisomerase III Comprise a Novel DNA Strand Passage Function
1999
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice
1999 StandoutNobel
Mechanisms linking obesity to insulin resistance and type 2 diabetes
2006 StandoutNature
Surface-Enhanced Emission from Single Semiconductor Nanocrystals
2002 StandoutNobel
Mechanisms of cellular senescence
1997
Osteoclast differentiation and activation
2003 StandoutNature
The Bloom's Syndrome Gene Product Is a 3′-5′ DNA Helicase
1997
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Male–female differences in fertility and blood pressure in ACE-deficient mice
1995 StandoutNatureNobel
RecQ helicases: caretakers of the genome
2003
Extrachromosomal rDNA Circles— A Cause of Aging in Yeast
1997
Topoisomerase III is essential for accurate nuclear division in Schizosaccharomyces pombe
1999
Interaction between the N-terminus of human topoisomerase I and SV40 large T antigen
1998
Genetic analysis of ageing: role of oxidative damage and environmental stresses
1996
RNA interference
2002 StandoutNature
Somatic mutagenesis and antimutagenesis in aging research
1996
Progress and challenges in translating the biology of atherosclerosis
2011 StandoutNature
A phylogenomic study of DNA repair genes, proteins, and processes
1999
Molecular mechanisms of yeast aging
1998
Genetics of Type 2 diabetes
2005
Angiotensin Converting Enzyme Gene Polymorphism Is Not Related to Essential Hypertension in a Greek Population
1996
The Hallmarks of Aging
2013 Standout
A pdf Neuropeptide Gene Mutation and Ablation of PDF Neurons Each Cause Severe Abnormalities of Behavioral Circadian Rhythms in Drosophila
1999 StandoutNobel
DNA helicases in inherited human disorders
1997
A human DNA editing enzyme homologous to the Escherichia coli DnaQ/MutD protein
1999
Nonvalidation of Reported Genetic Risk Factors for Acute Coronary Syndrome in a Large-Scale Replication Study
2007
The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase
2001
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
2003 StandoutNature
Cloning and Characterization of DrosophilaTopoisomerase IIIβ
2000
The essential role of yeast topoisomerase III in meiosis depends on recombination
1999
Telomeres, replicative senescence and human ageing
2001
DNA damage, vascular senescence and atherosclerosis
2008
The role of nuclear architecture in genomic instability and ageing
2007
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Blood Pressures and Cardiovascular Homeostasis in Mice Having Reduced or Absent Angiotensin-Converting Enzyme Gene Function
1997 StandoutNobel
Chemical Topology: Complex Molecular Knots, Links, and Entanglements
2011 StandoutNobel
Posttranscriptional Gene Silencing in Neurospora by a RecQ DNA Helicase
1999 Science
Optical forces between metallic particles
2005 StandoutNobel
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Genetic Linkage of the ACE Gene to Plasma Angiotensin-Converting Enzyme Activity but Not to Blood Pressure
1995
The Free Radical Theory of Aging Matures
1998 Standout
Mammalian DNA topoisomerase IIIα is essential in early embryogenesis
1998
Telomere length is paternally inherited and is associated with parental lifespan
2007 StandoutNobel
Quality Control by DNA Repair
1999 StandoutScienceNobel
Homology modeling of an RNP domain from a human RNA-binding protein: Homology-constrained energy optimization provides a criterion for distinguishing potential sequence alignments
1998
Diabetic nephropathy is markedly enhanced in mice lacking the bradykinin B2 receptor
2004 StandoutNobel
Genetically increased angiotensin I-converting enzyme level and renal complications in the diabetic mouse
2001 StandoutNobel
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
2002 StandoutNobel
Genetics of Aging
1997 Science
Angiotensin converting enzyme gene deletion allele is independently and strongly associated with coronary atherosclerosis and myocardial infarction.
1995
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair
2001 StandoutNobel
The Bloom's syndrome gene product promotes branch migration of Holliday junctions
2000
WRN Helicase and FEN-1 Form a Complex upon Replication Arrest and Together Process Branchmigrating DNA Structures Associated with the Replication Fork
2003
Accurate protein structure modeling using sparse NMR data and homologous structure information
2012 StandoutNobel
Population genetics of dinucleotide (dC-dA)n.(dG-dT)n polymorphisms in world populations.
1995
Werner syndrome protein interacts functionally with translesion DNA polymerases
2007
Mismatch repair in extracts of Werner syndrome cell lines.
1997
Aging, life span, and senescence
1998 StandoutNobel
Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins
1996 StandoutScienceNobel
Natriuretic peptide receptor 1 expression influences blood pressures of mice in a dose-dependent manner
1998 StandoutNobel
Molecular and Behavioral Analysis of Four period Mutants in Drosophila melanogaster Encompassing Extreme Short, Novel Long, and Unorthodox Arrhythmic Types
1998 StandoutNobel
Complementary roles of gasotransmitters CO and H2S in sleep apnea
2017 StandoutNobel
Angiotensin-converting enzyme and male fertility
1998 StandoutNobel
Accelerated Aging and Nucleolar Fragmentation in Yeast sgs1 Mutants
1997 Science
The biology of aging: 1985–2010 and beyond
2011
New directions in single-molecule imaging and analysis
2007 StandoutNobel
Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III
1997 StandoutNobel
Single Molecule Fluorescence Spectroscopy at Ambient Temperature
1999
Flap Endonuclease 1: A Central Component of DNA Metabolism
2004
Interaction between Yeast Sgs1 Helicase and DNA Topoisomerase III
2000
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
2008 StandoutNobel
Angiotensin-Converting Enzyme Gene Mutations, Blood Pressures, and Cardiovascular Homeostasis
1997 StandoutNobel
Human DNA Repair Genes
2001 StandoutScienceNobel
Mouse models of abnormal skeletal development and homeostasis
2001
Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region
1996 StandoutScience
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1
2004 StandoutNobel
Gene Expression Profile of Aging and Its Retardation by Caloric Restriction
1999 Science
Surface Enhanced Raman Spectroscopy of Individual Rhodamine 6G Molecules on Large Ag Nanocrystals
1999 StandoutNobel
Longevity, Genes, and Aging
1996 Science
Reduced growth, abnormal kidney structure, and type 2 (AT 2 ) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT 1A and AT 1B receptors for angiotensin II
1998 StandoutNobel
DNA Topoisomerases: Structure, Function, and Mechanism
2001 Standout
Works of Jun Nakura being referenced
Association Analysis of a Polymorphism of the Angiotensin Converting Enzyme Gene with Essential Hypertension in the Japanese Population
1993
Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) in patients with coexistent hypertrophic cardiomyopathy and coronary spastic angina
2005
Population variation in the dinucleotide repeat polymorphism at the D8S360 locus
1993
Association of a polymorphic variant of the Werner helicase gene with myocardial infarction in a Japanese population
1997
Mutations in the consensus helicase domains of the Werner syndrome gene. Werner's Syndrome Collaborative Group.
1997
Linkage disequilibrium and haplotype studies of chromosome 8p 11.1-21.1 markers and Werner syndrome.
1994
Positional Cloning of the Werner's Syndrome Gene
1996 Science
Toward localization of the Werner syndrome gene by linkage disequilibrium and ancestral haplotyping: lessons learned from analysis of 35 chromosome 8p11.1-21.1 markers.
1996