Citation Impact
Citing Papers
NOTCH Signaling Is Required for Formation and Self-Renewal of Tumor-Initiating Cells and for Repression of Secretory Cell Differentiation in Colon Cancer
2010 StandoutNobel
Association of COMT and PRODH gene variants with intelligence quotient (IQ) and executive functions in 22q11.2DS subjects
2014
Schizophrenia risk from complex variation of complement component 4
2016 StandoutNature
Comparative mapping of the 22q11.2 deletion region and the potential of simple model organisms
2015
The Structural Basis for mRNA Recognition and Cleavage by the Ribosome-Dependent Endonuclease RelE
2009 StandoutNobel
Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model
2008
Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions
2024 StandoutNobel
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Physiological and behavioural responsivity to stress and anxiogenic stimuli in COMT-deficient mice
2011
Imaging beyond the proteome
2012 StandoutNobel
Impaired hippocampal–prefrontal synchrony in a genetic mouse model of schizophrenia
2010 Nature
Ligand-Dependent Cleavage of the P75 Neurotrophin Receptor Is Necessary for NRIF Nuclear Translocation and Apoptosis in Sympathetic Neurons
2006
A Coordinated Local Translational Control Point at the Synapse Involving Relief from Silencing and MOV10 Degradation
2009
Bex1 is involved in the regeneration of axons after injury
2010
Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α
2009 Standout
Psychiatric Disorders and Intellectual Functioning Throughout Development in Velocardiofacial (22q11.2 Deletion) Syndrome
2009
DGCR8 HITS-CLIP reveals novel functions for the Microprocessor
2012
The T-box factor MLS-1 acts as a molecular switch during specification of nonstriated muscle in C. elegans
2002 StandoutNobel
Regulation of microRNA biogenesis
2014 Standout
The CD95(APO-1/Fas) DISC and beyond
2003
DHHC palmitoyl transferases: substrate interactions and (patho)physiology
2011
The many faces of p75NTR
2002
The neurobiology of zinc in health and disease
2005 Standout
The ground state of embryonic stem cell self-renewal
2008 StandoutNature
UV induced bystander signaling leading to apoptosis
2004
Modeling a model: Mouse genetics, 22q11.2 Deletion Syndrome, and disorders of cortical circuit development
2015
22q11.21 Deletion Syndromes: A Review of Proximal, Central, and Distal Deletions and Their Associated Features
2015 Standout
Properties of a monoclonal antibody directed to the calmodulin-binding domain of rabbit skeletal muscle myosin light chain kinase
1987 StandoutNobel
REPuter: the manifold applications of repeat analysis on a genomic scale
2001 Standout
Cognitive, Behavioural and Psychiatric Phenotype in 22q11.2 Deletion Syndrome
2011
Dynamic changes in gene expression profiles of 22q11 and related orthologous genes during mouse development
2007
Development of Single Retinofugal Axon Arbors in Normal and β2 Knock-Out Mice
2011
Zinc and 4-Hydroxy-2-Nonenal Mediate Lysosomal Membrane Permeabilization Induced by H2O2in Cultured Hippocampal Neurons
2008
Is there a core neuropsychiatric phenotype in 22q11.2 deletion syndrome?
2012
Signature MicroRNA expression patterns identified in humans with 22q11.2 deletion/DiGeorge syndrome
2013
Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
2013 StandoutNobel
Gamma-Secretase Represents a Therapeutic Target for the Treatment of Invasive Glioma Mediated by the p75 Neurotrophin Receptor
2008
Modern human changes in regulatory regions implicated in cortical development
2020
IKK/NF- B signaling: balancing life and death - a new approach to cancer therapy
2005 Standout
Proline Affects Brain Function in 22q11DS Children with the Low Activity COMT158 Allele
2008
Proline and COMT Status Affect Visual Connectivity in Children with 22q11.2 Deletion Syndrome
2011
Association of AKT1 with schizophrenia confirmed in a Japanese population
2004
The widespread regulation of microRNA biogenesis, function and decay
2010 Standout
Rethinking schizophrenia
2010 StandoutNature
Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system
2000
Ranbp1, Deleted in DiGeorge/22q11.2 Deletion Syndrome, is a Microcephaly Gene That Selectively Disrupts Layer 2/3 Cortical Projection Neuron Generation
2014
Genetic and cognitive windows into circuit mechanisms of psychiatric disease
2011
A gene expression atlas of the central nervous system based on bacterial artificial chromosomes
2003 StandoutNature
Differential gene expression in the hippocampus of the Df1/+ mice: A model for 22q11.2 deletion syndrome and schizophrenia
2007
Leucine-Rich Repeat Transmembrane Proteins Are Essential for Maintenance of Long-Term Potentiation
2013 StandoutNobel
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
miRNAs in brain development
2013
The 22q11 deletion: DiGeorge and velocardiofacial syndromes and the role of TBX1
2012
Alterations in Midline Cortical Thickness and Gyrification Patterns Mapped in Children with 22q11.2 Deletions
2008
When Half Is Not Enough: Gene Expression and Dosage in the 22q11 Deletion Syndrome
2006
Candidate genes and the behavioral phenotype in 22q11.2 deletion syndrome
2008
Dendritic spine pathology in schizophrenia
2012
Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
2013 Standout
Honokiol, a Small Molecular Weight Natural Product, Inhibits Angiogenesis in Vitro and Tumor Growth in Vivo
2003 Standout
Schizophrenia-like neurophysiological abnormalities in 22q11.2 deletion syndrome and their association to COMT and PRODH genotypes
2013
Co-induction of p75NTR and the associated death executor NADE in degenerating hippocampal neurons after kainate-induced seizures in the rat
2003
22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia
2010
MicroRNA Dysregulation, Gene Networks, and Risk for Schizophrenia in 22q11.2 Deletion Syndrome
2014
Cognition in Mouse Models of Schizophrenia Susceptibility Genes
2009
Decreased DGCR8 Expression and miRNA Dysregulation in Individuals with 22q11.2 Deletion Syndrome
2014
Derepression of a Neuronal Inhibitor due to miRNA Dysregulation in a Schizophrenia-Related Microdeletion
2013
Modeling psychiatric disorders at the cellular and network levels
2012
Neurobiology of Schizophrenia
2006
Abnormal cortical activation during response inhibition in 22q11.2 deletion syndrome
2007
The TNF and TNF Receptor Superfamilies
2001 Standout
Association between autism spectrum disorder in individuals with velocardiofacial (22q11.2 deletion) syndrome and PRODH and COMT genotypes
2014
COMT Val108/158Met Modifies Mismatch Negativity and Cognitive Function in 22q11 Deletion Syndrome
2005
22q11.2 deletion syndrome
2015 Standout
Neuroanatomical phenotypes in a mouse model of the 22q11.2 microdeletion
2013
Modeling Madness in Mice: One Piece at a Time
2006
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Mechanisms of Apoptosis
2000
MAPK/ERK Overrides the Apoptotic Signaling from Fas, TNF, and TRAIL Receptors
2001
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Caspase Activation Inhibits Proteasome Function during Apoptosis
2004 StandoutNobel
The kinesin KIF1Bβ acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor
2008 StandoutNobel
Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner
2012 Standout
Quadruplex DNA: sequence, topology and structure
2006 Standout
The p75 Neurotrophin Receptor Activates Akt (Protein Kinase B) through a Phosphatidylinositol 3-Kinase-dependent Pathway
2001
A catechol- O -methyltransferase that is essential for auditory function in mice and humans
2008 StandoutNobel
Activation of Rac GTPase by p75 Is Necessary for c-junN-Terminal Kinase-Mediated Apoptosis
2002
2-Bromopalmitate Analogues as Activity-Based Probes To Explore Palmitoyl Acyltransferases
2013
Luminescent Chemodosimeters for Bioimaging
2012 Standout
Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems.
1992 StandoutNobel
Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing
2012
Exploring Protein Lipidation with Chemical Biology
2011
STRINGENT CONTROL IN E. COLI
1979
A Synaptic Function Approach to Investigating Complex Psychiatric Diseases
2013
The kinetics of tyrosine phosphorylation by the purified epidermal growth factor receptor kinase of A-431 cells.
1983 StandoutNobel
Processing of microRNA primary transcripts requires heme in mammalian cells
2014
Analysis of substrate specificity of human DHHC protein acyltransferases using a yeast expression system
2012
Targeting protein palmitoylation: selective inhibitors and implications in disease
2014
Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: Implications for 22q11 deletion syndrome
2006
Trk Receptors: Roles in Neuronal Signal Transduction
2003 Standout
Cyclic AMP-dependent protein kinase I: Cyclic nucleotide binding, structural changes, and release of the catalytic subunits
1981 StandoutNobel
AnFgf8mouse mutant phenocopies human 22q11 deletion syndrome
2002 StandoutNobel
ProTox-II: a webserver for the prediction of toxicity of chemicals
2018 Standout
Three phases of DiGeorge/22q11 deletion syndrome pathogenesis during brain development: Patterning, proliferation, and mitochondrial functions of 22q11 genes
2010
Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery
2013
Click-Chemistry Based High Throughput Screening Platform for Modulators of Ras Palmitoylation
2017 StandoutNobel
Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family.
1992 StandoutNobel
Fluorescent Sensors for Measuring Metal Ions in Living Systems
2014 Standout
Co-Induction of p75NTRand p75NTR-Associated Death Executor in Neurons After Zinc Exposure in Cortical Culture or Transient Ischemia in the Rat
2000
Role of Leucine-Rich Repeat Proteins in the Development and Function of Neural Circuits
2011
Conditional Deletion of Focal Adhesion Kinase Leads to Defects in Ventricular Septation and Outflow Tract Alignment
2007 StandoutNobel
Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies
2018
(p)ppGpp: Still Magical?
2008
Diminished dosage of 22q11 genes disrupts neurogenesis and cortical development in a mouse model of 22q11 deletion/DiGeorge syndrome
2009
Heterologous enzyme function in Escherichia coli and the selection of genes encoding the catalytic RNA subunit of RNase P.
1987 StandoutNobel
The enzymatic preparation of [α-32P]nucleoside triphosphates, cyclic [32P]AMP, and cyclic [32P]GMP
1979
Deficits in microRNA-mediated Cxcr4/Cxcl12 signaling in neurodevelopmental deficits in a 22q11 deletion syndrome mouse model
2013
Depletion of intracellular potassium arrests coated pit formation and receptor-mediated endocytosis in fibroblasts
1983 StandoutNobel
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
The Genetic Architecture of Schizophrenia: New Mutations and Emerging Paradigms
2011
Whole-Genome Sequencing and Integrative Genomic Analysis Approach on Two 22q11.2 Deletion Syndrome Family Trios for Genotype to Phenotype Correlations
2015
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
Neurodevelopmental Outcomes in Children With Congenital Heart Disease: Evaluation and Management
2012 Standout
Genetic evidence that brain-derived neurotrophic factor mediates competitive interactions between individual cortical neurons
2012
Works of Jun Mukai being referenced
14-3-3 Is Involved in p75 Neurotrophin Receptor-mediated Signal Transduction
2001
Nogo Receptor 1 (RTN4R) as a Candidate Gene for Schizophrenia: Analysis Using Human and Mouse Genetic Approaches
2007
Molecular Substrates of Altered Axonal Growth and Brain Connectivity in a Mouse Model of Schizophrenia
2015
Nerve Growth Factor-Dependent Regulation of NADE-Induced Apoptosis
2003
S-Nitrosylation and S-Palmitoylation Reciprocally Regulate Synaptic Targeting of PSD-95
2011
Structure-Function Analysis of NADE
2002
Palmitoylation-dependent neurodevelopmental deficits in a mouse model of 22q11 microdeletion
2008
Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia
2004
Negative regulation of Fas-mediated apoptosis by FAP-1 in human cancer cells
2000
Genetic Modulation of BDNF Signaling Affects the Outcome of Axonal Competition In Vivo
2007
Functional interaction of Fas‐associated phosphatase‐1 (FAP‐1) with p75NTR and their effect on NF‐κB activation
1999
Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice
2005
NADE, a p75NTR-associated Cell Death Executor, Is Involved in Signal Transduction Mediated by the Common Neurotrophin Receptor p75NTR
2000
The Pattern of Cortical Dysfunction in a Mouse Model of a Schizophrenia-Related Microdeletion
2013
Recapitulation and Reversal of Schizophrenia-Related Phenotypes in Setd1a-Deficient Mice
2019
Acceptor Specificity of ATP: Nucleoside-5′-Phosphate Pyrophosphotransferase from Streptomyces adephospholyticus
1978
The 22q11.2 microdeletion: Fifteen years of insights into the genetic and neural complexity of psychiatric disorders
2010
Enzymatic synthesis of [α32P]ATP of high specific activity
1976
Deficiency of Dgcr8 , a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex
2011
Nucleotide 2',3'-cyclic monophosphokinase from actinomycetes.
1990