Citation Impact
Citing Papers
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
2009 StandoutScience
microRNA-1246 Is an Exosomal Biomarker for Aggressive Prostate Cancer
2018
The Tpl2 Mutation Sluggish Impairs Type I IFN Production and Increases Susceptibility to Group B Streptococcal Disease
2009 StandoutNobel
Siglecs: A journey through the evolution of sialic acid-binding immunoglobulin-type lectins
2018
Siglec-mediated regulation of immune cell function in disease
2014
Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy
2019
Rab GTPases, intracellular traffic and disease
2002
RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction
2011 StandoutNobel
A cell that dies during wild-type C. elegans development can function as a neuron in a ced-3 mutant
1987 StandoutNobel
RAS oncogenes: the first 30 years
2003
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Presynaptic Neurexin-3 Alternative Splicing trans-Synaptically Controls Postsynaptic AMPA Receptor Trafficking
2013 StandoutNobel
MEKKs, GCKs, MLKs, PAKs, TAKs, and Tpls: upstream regulators of the c-Jun amino-terminal kinases?
1997
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
Disruption of the Mouse Rce1 Gene Results in Defective Ras Processing and Mislocalization of Ras within Cells
1999
Plant and Animal Pathogen Recognition Receptors Signal through Non-RD Kinases
2006
Doc2 Supports Spontaneous Synaptic Transmission by a Ca2+-Independent Mechanism
2011
ELKS2α/CAST Deletion Selectively Increases Neurotransmitter Release at Inhibitory Synapses
2009 StandoutNobel
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
1994 StandoutScienceNobel
Innate immune recognition of, and regulation by, DNA
2006
NF-κB1/p105 Regulates Lipopolysaccharide-Stimulated MAP Kinase Signaling by Governing the Stability and Function of the Tpl2 Kinase
2003
Synaptic Cell Adhesion
2012
Identification of Putative Target Genes of the Transcription Factor RUNX2
2013 StandoutNobel
Secondary Structure of Vertebrate Telomerase RNA
2000 StandoutNobel
MAP3K-related kinase involved in NF-KB induction by TNF, CD95 and IL-1
1997 Nature
The Control of Vascular Integrity by Endothelial Cell Junctions: Molecular Basis and Pathological Implications
2009
The MicroRNA miR-1 Regulates a MEF-2-Dependent Retrograde Signal at Neuromuscular Junctions
2008 StandoutNobel
Rab3A negatively regulates activity‐dependent modulation of exocytosis in bovine adrenal chromaffin cells
2003
Therapeutic Targeting of Siglecs using Antibody- and Glycan-Based Approaches
2015
Differential Regulation of Synaptic Vesicle Tethering and Docking by UNC-18 and TOM-1
2010
A Complete Genetic Analysis of Neuronal Rab3 Function
2004 StandoutNobel
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Sialic Acid Mimetics to Target the Sialic Acid–Siglec Axis
2016
The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells
2003 StandoutNobel
The plant immune system
2006 StandoutNature
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
A Complexin/Synaptotagmin 1 Switch Controls Fast Synaptic Vesicle Exocytosis
2006 StandoutNobel
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
MDGAs interact selectively with neuroligin-2 but not other neuroligins to regulate inhibitory synapse development
2012 StandoutNobel
Cell Biology of the Glomerular Podocyte
2003 Standout
A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα
2010 StandoutNobel
Small GTP-Binding Proteins
2001 Standout
Tumor progression locus 2 (Tpl-2) encodes a protein kinase involved in the progression of rodent T-cell lymphomas and in T-cell activation.
1993
Secondary structure of the Tetrahymena ribosomal RNA intervening sequence: structural homology with fungal mitochondrial intervening sequences.
1983 StandoutNobel
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells
2006
PROCESSED PSEUDOGENES: CHARACTERISTICS AND EVOLUTION
1985
Programmed assembly of 3-dimensional microtissues with defined cellular connectivity
2009 StandoutNobel
The human cot proto-oncogene encodes two protein serine/threonine kinases with different transforming activities by alternative initiation of translation.
1993
RIM-Binding Protein, a Central Part of the Active Zone, Is Essential for Neurotransmitter Release
2011 StandoutScienceNobel
Transduction of a cellular oncogene: the genesis of Rous sarcoma virus.
1983 StandoutNobel
Mechanism of activation of an N-ras gene in the human fibrosarcoma cell line HT1080.
1984
An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins
1987 StandoutNatureNobel
Death Receptors: Signaling and Modulation
1998 StandoutScience
Nucleotide sequence of cloned unintegrated avian sarcoma virus DNA: viral DNA contains direct and inverted repeats similar to those in transposable elements.
1981 StandoutNobel
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
X-ray crystal structures of transforming p21 ras mutants suggest a transition-state stabilization mechanism for GTP hydrolysis.
1992
Lipopolysaccharide Activation of the TPL-2/MEK/Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase Cascade Is Regulated by IκB Kinase-Induced Proteolysis of NF-κB1 p105
2004
Tpl-2 is an oncogenic kinase that is activated by carboxy-terminal truncation.
1997
Increased Incidence of Squamous Cell Carcinomas in Mastomys natalensis Papillomavirus E6 Transgenic Mice during Two-Stage Skin Carcinogenesis
2004 StandoutNobel
In vitro splicing of the ribosomal RNA precursor of tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequence
1981 StandoutNobel
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases
2002 StandoutScience
RIM genes differentially contribute to organizing presynaptic release sites
2012 StandoutNobel
LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23).
2002
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
TPL-2 negatively regulates interferon-β production in macrophages and myeloid dendritic cells
2009
Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning
2011 StandoutNobel
Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human
1999 Standout
Fission yeast orb 6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycle
1998 StandoutNobel
Coordinating TLR‐activated signaling pathways in cells of the immune system
2007
Nucleotide sequence of a ribosomal RNA gene intron from slime mold Physarum polycephalum.
1981
Multiple Mitogen-Activated Protein Kinase Signaling Pathways Connect the Cot Oncoprotein to the c-junPromoter and to Cellular Transformation
2000
Nucleotide sequence to the v-myc oncogene of avian retrovirus MC29.
1983 StandoutNobel
Transposable elements
1980
Regulation of Synaptic Transmission by RAB-3 and RAB-27 inCaenorhabditis elegans
2006
Tpl2 kinase regulates T cell interferon-γ production and host resistance to Toxoplasma gondii
2008
Role of conserved sequence elements 9L and 2 in self-splicing of the Tetrahymena ribosomal RNA precursor
1986 StandoutNobel
Plant and Animal Sensors of Conserved Microbial Signatures
2010 StandoutScienceNobel
A Rous sarcoma virus provirus is flanked by short direct repeats of a cellular DNA sequence present in only one copy prior to integration.
1981 StandoutNobel
Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase.
1996
Unique insertion site of Tn7 in the E. coli chromosome
1982 StandoutNatureNobel
Molecular cloning and characterization of a conserved nuclear serine(threonine) protein kinase.
1995
Works of Jun Miyoshi being referenced
Interneurite affinity is regulated by heterophilic nectin interactions in concert with the cadherin machinery
2006
Siglec-15 Protein Regulates Formation of Functional Osteoclasts in Concert with DNAX-activating Protein of 12 kDa (DAP12)
2012
Nectins and nectin-like molecules: roles in contact inhibition of cell movement and proliferation
2008
Progressive impairment of kidneys and reproductive organs in mice lacking Rho GDIα
1999
Systems Analysis of ATF3 in Stress Response and Cancer Reveals Opposing Effects on Pro-Apoptotic Genes in p53 Pathway
2011
K-Ras is essential for the development of the mouse embryo
1997
Targeted deletion of the H-ras gene decreases tumor formation in mouse skin carcinogenesis
2000
The Murine cot Proto‐oncogene: Genome Structure and Tissue‐specific Expression
1993
A serine/threonine kinase, Cot/Tpl2, modulates bacterial DNA–induced IL-12 production and Th cell differentiation
2004
Involvement of a Small GTP-binding Protein (G Protein) Regulator, Small G Protein GDP Dissociation Stimulator, in Antiapoptotic Cell Survival Signaling
2000
Doc2α and Munc13-4 Regulate Ca2+-Dependent Secretory Lysosome Exocytosis in Mast Cells
2008
DNA sequences of the integration sites and “inverted repeated structure of transposon Tn3
1979
Hamster cell line suitable for transfection assay of transforming genes.
1990
Structure and Transforming Potential of the Human cot Oncogene Encoding a Putative Protein Kinase
1991
Role of Rab GDP dissociation inhibitor α in regulating plasticity of hippocampal neurotransmission
2000
Structure and transforming potential of the human cot oncogene encoding a putative protein kinase.
1991
Dual inhibition of SNARE complex formation by tomosyn ensures controlled neurotransmitter release
2008
Afadin
1999
Identification and characterization of protein products of the cot oncogene with serine kinase activity.
1991
A GDP/GTP exchange protein for the Rab3 small G protein family up-regulates a postdocking step of synaptic exocytosis in central synapses
2002
The human c-Ha-ras2 is a processed pseudogene inactivated by numerous base substitutions
1984
Role of Rab3 GDP/GTP Exchange Protein in Synaptic Vesicle Trafficking at the Mouse Neuromuscular Junction
2001