Citation Impact
Citing Papers
Systemic 4-1BB activation induces a novel T cell phenotype driven by high expression of Eomesodermin
2013 StandoutNobel
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
Synaptic Pruning by Microglia Is Necessary for Normal Brain Development
2011 StandoutScience
IL-27 Blocks RORc Expression to Inhibit Lineage Commitment of Th17 Cells
2009
Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease
2006
Temporal gene profiling of the 5XFAD transgenic mouse model highlights the importance of microglial activation in Alzheimer’s disease
2014
Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation
2019 StandoutNobel
Mechanisms and Functional Implications of Adult Neurogenesis
2008 Standout
IL‐23 leads to diabetes induction after subdiabetogenic treatment with multiple low doses of streptozotocin
2005
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
2006 Standout
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Control of microglial neurotoxicity by the fractalkine receptor
2006
Tumor Necrosis Factor Receptor 1 Is a Negative Regulator of Progenitor Proliferation in Adult Hippocampal Neurogenesis
2006
Neurotransmitter, peptide and cytokine processes in relation to depressive disorder: Comorbidity between depression and neurodegenerative disorders
2008
Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4
2017 StandoutNobel
Microglia and neuroprotection: From in vitro studies to therapeutic applications
2010
Characteristics and roles of the volume-sensitive outwardly rectifying (VSOR) anion channel in the central nervous system
2014
Rett Syndrome Microglia Damage Dendrites and Synapses by the Elevated Release of Glutamate
2010
Neuronal Chemokines: Versatile Messengers In Central Nervous System Cell Interaction
2007
Microglia Activated with the Toll-Like Receptor 9 Ligand CpG Attenuate Oligomeric Amyloid β Neurotoxicity in in Vitro and in Vivo Models of Alzheimer’s Disease
2009
Mechanisms of Microglia-Mediated Neurotoxicity in a New Model of the Stroke Penumbra
2008
IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells
2007 StandoutNature
Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model
2007 Standout
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer’s Disease Model
2015 Standout
Decoding ALS: from genes to mechanism
2016 StandoutNature
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Neuroinflammation: Implications for the Pathogenesis and Molecular Diagnosis of Alzheimer's Disease
2007
Activation of microglial N‐methyl‐D‐aspartate receptors triggers inflammation and neuronal cell death in the developing and mature brain
2012
Interleukin-17 and Type 17 Helper T Cells
2009 Standout
HIV-infection of the central nervous system: the tightrope walk of innate immunity
2004
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds
1993 StandoutNature
Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease
2008
Connexin 43 is an emerging therapeutic target in ischemia/reperfusion injury, cardioprotection and neuroprotection
2015
Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
2010 StandoutNature
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
Interleukin 27 negatively regulates the development of interleukin 17–producing T helper cells during chronic inflammation of the central nervous system
2006
Astrocytes conspire with neurons during progression of neurological disease
2012
Regulation of Tau Pathology by the Microglial Fractalkine Receptor
2010
Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System
2008
Glutamate release from activated microglia requires the oxidative burst and lipid peroxidation
2007
Janus faces of microglia in multiple sclerosis
2007
Neuronal ‘On’ and ‘Off’ signals control microglia
2007
Characterization of the dipeptide repeat protein in the molecular pathogenesis of c9FTD/ALS
2014
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
2007 StandoutNatureNobel
A role for tumor necrosis factor-α in ischemia and ischemic preconditioning
2011
Connexin channel permeability to cytoplasmic molecules
2007
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
CX3CL1/fractalkine regulates branching and migration of monocyte-derived cells in the mouse olfactory epithelium
2008
Connexins, pannexins, innexins: novel roles of “hemi-channels”
2008
Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
2013 Standout
Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases
2004
Cross-talk between calcium and cAMP-dependent intracellular signaling pathways. Implications for synergistic secretion in T84 colonic epithelial cells and rat pancreatic acinar cells.
1995 StandoutNobel
Th9 cells promote antitumor immune responses in vivo
2012
Toll‐like receptor 4 contributes to poor outcome after intracerebral hemorrhage
2011 StandoutNobel
Glial dysfunction in the pathogenesis of α-synucleinopathies: emerging concepts
2011
Myeloid cells — targets of medication in multiple sclerosis
2016
Glia and alpha-synuclein in neurodegeneration: A complex interaction
2015
Excitatory Amino Acids as a Final Common Pathway for Neurologic Disorders
1994 Standout
The P2X7Receptor Drives Microglial Activation and Proliferation: A Trophic Role for P2X7R Pore
2009
Macrophage-induced neurotoxicity is mediated by glutamate and attenuated by glutaminase inhibitors and gap junction inhibitors
2008
Chapter 5 Emergence of the Th17 Pathway and Its Role in Host Defense
2008
Microglia: biology and pathology
2009
The molecular neurobiology of depression
2008 StandoutNature
Peroxynitrite: biochemistry, pathophysiology and development of therapeutics
2007 Standout
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength
2016 StandoutNobel
Neuron-microglia signaling: Chemokines as versatile messengers
2008
Differentiation and Immune Regulation of IL-9−Producing CD4 + T Cells in Malignant Pleural Effusion
2012
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
IFN-γ Limits Th9-Mediated Autoimmune Inflammation through Dendritic Cell Modulation of IL-27
2012
Regulation of Dynamic Behavior of Retinal Microglia by CX3CR1 Signaling
2009
Spinal cord oligodendrocyte‐derived alarmin IL‐33 mediates neuropathic pain
2015
Pain regulation by non-neuronal cells and inflammation
2016 StandoutScience
Multiple Sclerosis
2018 Standout
Fast structural responses of gap junction membrane domains to AB5 toxins
2013 StandoutNobel
Spatial distribution of calcium channels and cytosolic calcium transients in growth cones and cell bodies of sympathetic neurons.
1988 StandoutNobel
Inflammation as a central mechanism in Alzheimer's disease
2018 Standout
A Family of AMPA-Selective Glutamate Receptors
1990 StandoutScienceNobel
Th9 cells: differentiation and disease
2013
Activation of a potassium current by rapid photochemically generated step increases of intracellular calcium in rat sympathetic neurons.
1987 StandoutNobel
Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors.
1992 StandoutNobel
Modulation of three key innate immune pathways for the most common retinal degenerative diseases
2018
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
The 5HT2 receptor defines a family of structurally distinct but functionally conserved serotonin receptors.
1990 StandoutNobel
Fractalkine in the nervous system: neuroprotective or neurotoxic molecule?
2015
Rat brain serotonin receptors in Xenopus oocytes are coupled by intracellular calcium to endogenous channels.
1987 StandoutNobel
Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.
1990 Standout
Oxidative Stress, Glutamate, and Neurodegenerative Disorders
1993 StandoutScience
Crosslinkage of B lymphocyte surface immunoglobulin by anti-Ig or antigen induces prolonged oscillation of intracellular ionized calcium.
1987 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Tissue-specific expression of B7x protects from CD4 T cell–mediated autoimmunity
2011 StandoutNobel
Central Role for MyD88 in the Responses of Microglia to Pathogen-Associated Molecular Patterns
2006
The Cytolytic P 2Z Receptor for Extracellular ATP Identified as a P 2X Receptor (P2X 7 )
1996 StandoutScience
Expression of GM-CSF in T Cells Is Increased in Multiple Sclerosis and Suppressed by IFN-β Therapy
2015
EAT-4, a Homolog of a Mammalian Sodium-Dependent Inorganic Phosphate Cotransporter, Is Necessary for Glutamatergic Neurotransmission inCaenorhabditis elegans
1999 StandoutNobel
Physiology of Microglia
2011 Standout
Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes
1992 StandoutScienceNobel
Works of Jun Kawanokuchi being referenced
Fractalkine Attenuates Excito-neurotoxicity via Microglial Clearance of Damaged Neurons and Antioxidant Enzyme Heme Oxygenase-1 Expression
2010
The radical scavenger edaravone prevents oxidative neurotoxicity induced by peroxynitrite and activated microglia
2004
Glutamate induces neurotrophic factor production from microglia via protein kinase C pathway
2010
Production and functions of IL-33 in the central nervous system
2011
Production of IL-27 and other IL-12 family cytokines by microglia and their subpopulations
2005
Blockade of Gap Junction Hemichannel Suppresses Disease Progression in Mouse Models of Amyotrophic Lateral Sclerosis and Alzheimer's Disease
2011
Interferon-γ induces microglial-activation-induced cell death: A hypothetical mechanism of relapse and remission in multiple sclerosis
2005
Interferon-β is neuroprotective against the toxicity induced by activated microglia
2007
GM-CSF increases LPS-induced production of proinflammatory mediators via upregulation of TLR4 and CD14 in murine microglia
2012
Tumor Necrosis Factor-α Induces Neurotoxicity via Glutamate Release from Hemichannels of Activated Microglia in an Autocrine Manner
2006
Protective effects of nicergoline against neuronal cell death induced by activated microglia and astrocytes
2005
Autocrine activation of microglia by tumor necrosis factor-α
2005
Effects of interferon-β on microglial functions as inflammatory and antigen presenting cells in the central nervous system
2004
Production and neuroprotective functions of fractalkine in the central nervous system
2003
Production and functions of IL-17 in microglia
2008
Neuroprotective role of phosphodiesterase inhibitor ibudilast on neuronal cell death induced by activated microglia
2003
Neuritic Beading Induced by Activated Microglia Is an Early Feature of Neuronal Dysfunction Toward Neuronal Death by Inhibition of Mitochondrial Respiration and Axonal Transport
2005
IL-9 Promotes Th17 Cell Migration into the Central Nervous System via CC Chemokine Ligand-20 Produced by Astrocytes
2011
Production of interferon-γ by microglia
2006