Citation Impact
Citing Papers
Tumor Vaccines Expressing Flt3 Ligand Synergize with CTLA-4 Blockade to Reject Preimplanted Tumors
2009 StandoutNobel
PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors
2003 StandoutScience
Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences
2014
Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet
2009 Standout
Cip/Kip cyclin-dependent kinase inhibitors: brakes of the cell cycle engine during development
1999
A Senescence-Like Cell-Cycle Arrest Occurs During Megakaryocytic Maturation: Implications for Physiological and Pathological Megakaryocytic Proliferation
2010
Southwestern Internal Medicine Conference: Clinical Use of Hematopoietic Growth Factors
1993
CDK inhibitors: positive and negative regulators of G1-phase progression
1999 Standout
DIFFERENTIAL microRNA EXPRESSION IN CHILDHOOD B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA
2009
Flt3 Signaling-Dependent Dendritic Cells Protect against Atherosclerosis
2011 StandoutNobel
Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth
1995
Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu
2008 StandoutNature
Role of PPARγ in Regulating a Cascade Expression of Cyclin-dependent Kinase Inhibitors, p18(INK4c) and p21(Waf1/Cip1), during Adipogenesis
1999
Oncogenic kinase signalling
2001 StandoutNature
Efficacy of Gefitinib, an Inhibitor of the Epidermal Growth Factor Receptor Tyrosine Kinase, in Symptomatic Patients With Non–Small Cell Lung Cancer
2003 Standout
Dissemination and growth of cancer cells in metastatic sites
2002 Standout
Flt3 in Regulation of Type I Interferon‐Producing Cell and Dendritic Cell Development
2007
The IL-7 Receptor Controls the Accessibility of the TCRγ Locus by Stat5 and Histone Acetylation
2001 StandoutNobel
Stat3 as an Oncogene
1999 Standout
Adult Cardiac Stem Cells Are Multipotent and Support Myocardial Regeneration
2003 Standout
Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product.
1993
Stimulation of 3T3-L1 Adipogenesis by Signal Transducer and Activator of Transcription 5
2002
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
2011 StandoutNatureNobel
Targeting Stat3 blocks both HIF-1 and VEGF expression induced by multiple oncogenic growth signaling pathways
2005 StandoutNobel
The human papillomavirus E7 oncoprotein can uncouple cellular differentiation and proliferation in human keratinocytes by abrogating p21Cip1-mediated inhibition of cdk2
1997
The biology of VEGF and its receptors
2003 Standout
Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein
1993 Standout
FLT3: Receptor and Ligand. Biology and Potential Clinical Application
1998
Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma
2001
Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF
2004 Standout
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Interleukin 6 and its Receptor: Ten Years Later
1998
The hepatocyte growth factor/Met pathway controls proliferation and apoptosis in multiple myeloma
2003
c‐kit proto‐oncogene exon 8 in‐frame deletion plus insertion mutations in acute myeloid leukaemia
1999
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
VEGF receptor signalling ? in control of vascular function
2006 Standout
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
2006 StandoutNature
Papillomaviruses and cancer: from basic studies to clinical application
2002 StandoutNobel
Functional Interaction of STAT3 Transcription Factor with the Cell Cycle Inhibitor p21
2000
Endothelial receptor tyrosine kinases activate the STAT signaling pathway: mutant Tie-2 causing venous malformations signals a distinct STAT activation response
1999
p21 in cancer: intricate networks and multiple activities
2009 Standout
Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
2005 Standout
Chlovalicin, a New Cytocidal Antibiotic Produced by Sporothrix sp. FO-4649. I Taxonomy, Fermentation, Isolation and Biological Activities.
1996 StandoutNobel
Classes of c-KIT activating mutations: proposed mechanisms of action and implications for disease classification and therapy
2001
STAT5 as a molecular regulator of proliferation, differentiation and apoptosis in hematopoietic cells
1999
Dexamethasone Induces Apoptosis in Proliferative Chondrocytes through Activation of Caspases and Suppression of the Akt-Phosphatidylinositol 3′-Kinase Signaling Pathway
2004
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
2013 Standout
Rheumatoid arthritis
2010 Standout
Met, metastasis, motility and more
2003 Standout
Transcriptional Regulation of the p21(WAF1/CIP1)Gene
1999
Stat5 Is Essential for the Myelo- and Lymphoproliferative Disease Induced by TEL/JAK2
2000
Mr Outside and Mr Inside: classic and alternative views on the pathogenesis of rheumatoid arthritis
2010
Paraffin section detection of the c-kit gene product (CD 117) in human tissues: Value in the diagnosis of mast cell disorders
1998
Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells
1999
Adipocyte differentiation from the inside out
2006 Standout
Receptor tyrosine kinases in normal and malignant haematopoiesis
2003
Cytokine Signaling in 2002
2002 Standout
A Gain-of-Function Mutation of JAK2 in Myeloproliferative Disorders
2005 Standout
Inhibition of Papillomavirus Protein Function in Cervical Cancer Cells by Intrabody Targeting
2005 StandoutNobel
Cellular senescence: from physiology to pathology
2014 Standout
STATs: transcriptional control and biological impact
2002 Standout
I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development
2010 StandoutNobel
The biology of signal transduction inhibition: Basic science to novel therapies
2001
Development of Monocytes, Macrophages, and Dendritic Cells
2010 StandoutScience
Mosaic Prophages with Horizontally Acquired Genes Account for the Emergence and Diversification of the Globally Disseminated M1T1 Clone of Streptococcus pyogenes
2005
Binding of Ovarian Cancer Antigen CA125/MUC16 to Mesothelin Mediates Cell Adhesion
2004 Standout
HOW CELLS RESPOND TO INTERFERONS
1998 Standout
Transcriptional regulation of adipogenesis
2000 Standout
Apoptosis in the Pathogenesis and Treatment of Disease
1995 StandoutScience
Ligand-independent activation of c-kit receptor tyrosine kinase in a murine mastocytoma cell line P-815 generated by a point mutation
1994
Reduced expression of vascular cell adhesion molecule-1 on bone marrow stromal cells isolated from marrow transplant recipients correlates with a reduced capacity to support human B lymphopoiesis in vitro
1995
Rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences using Gubbins
2014 Standout
After chronic myelogenous leukemia: tyrosine kinase inhibitors in other hematologic malignancies
2004
Gain-of-Function Mutations of c- kit in Human Gastrointestinal Stromal Tumors
1998 StandoutScience
The role of microRNA genes in papillary thyroid carcinoma
2005 Standout
Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
2002 Standout
Normal and Oncogenic Forms of the Receptor Tyrosine Kinase Kit
2005
Stem Cell Factor and Hematopoiesis
1997
Constitutive activation of c-kit in FMA3 murine mastocytoma cells caused by deletion of seven amino acids at the juxtamembrane domain
1996
MD-2, a Molecule that Confers Lipopolysaccharide Responsiveness on Toll-like Receptor 4
1999 Standout
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Ineffective erythropoiesis in Stat5a−/−5b−/− mice due to decreased survival of early erythroblasts
2001
Constitutively activating mutations of c-kit receptor tyrosine kinase confer factor-independent growth and tumorigenicity of factor-dependent hematopoietic cell lines
1995
A phase 1 study of SU11248 in the treatment of patients with refractory or resistant acute myeloid leukemia (AML) or not amenable to conventional therapy for the disease
2005
BST-1, a surface molecule of bone marrow stromal cell lines that facilitates pre-B-cell growth.
1994
Immunobiology of Dendritic Cells
2000 Standout
Low c-kit expression of cultured mast cells of mi/mi genotype may be involved in their defective responses to fibroblasts that express the ligand for c-kit
1992
c-kit Ligand and Flt3 Ligand: Stem/Progenitor Cell Factors With Overlapping Yet Distinct Activities
1998
Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor–, granulocyte-macrophage colony-stimulating factor–, and interleukin-3–expressing NOD-SCID IL2Rγnull humanized mice
2011 StandoutNobel
A New IFN-Like Cytokine, Limitin Modulates the Immune Response Without Influencing Thymocyte Development
2001
Antiapoptotic activity ofStat5required during terminal stages of myeloid differentiation
2000
Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications
2002 Standout
Activation of the Flt3 signal transduction cascade rescues and enhances type I interferon–producing and dendritic cell development
2006
The antiangiogenic protein kinase inhibitors SU5416 and SU6668 inhibit the SCF receptor (c-kit) in a human myeloid leukemia cell line and in acute myeloid leukemia blasts
2001
Inhibition of KIT Tyrosine Kinase Activity: A Novel Molecular Approach to the Treatment of KIT-Positive Malignancies
2002
Increased invasiveness ofMUCI1 cDNA-transfected human gastric cancer MKN74 cells
1998
SHP-1 Binds and Negatively Modulates the c-Kit Receptor by Interaction with Tyrosine 569 in the c-Kit Juxtamembrane Domain
1998
Markedly Reduced Expression of Platelet c-mpl Receptor in Essential Thrombocythemia
1997
Mutation of the gastric hydrogen-potassium ATPase alpha subunit causes iron-deficiency anemia in mice
2011 StandoutNobel
Works of Jun Ishikawa being referenced
Changing prevalent T serotypes and emm genotypes of Streptococcus pyogenes isolates from streptococcal toxic shock-like syndrome (TSLS) patients in Japan
2003
GATA Transcription Factors Inhibit Cytokine-dependent Growth and Survival of a Hematopoietic Cell Line through the Inhibition of STAT3 Activity
2005
Insulin-like Growth Factor-I Augments Erythropoietin-induced Proliferation through Enhanced Tyrosine Phosphorylation of STAT5
1998
Thrombopoietin-Induced Differentiation of a Human Megakaryoblastic Leukemia Cell Line, CMK, Involves Transcriptional Activation of p21WAF1/Cip1 by STAT5
1997
The biologic properties of recombinant human thrombopoietin in the proliferation and megakaryocytic differentiation of acute myeloblastic leukemia cells
1996
Cytokines prevent dexamethasone-induced apoptosis via the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways in a new multiple myeloma cell line.
2000
Growth response of acute myeloblastic leukemia cells to recombinant human thrombopoietin
1995
Expression and functional role of the proto-oncogene c-kit in acute myeloblastic leukemia cells
1991
Human bone marrow stromal cell lines from myeloma and rheumatoid arthritis that can support murine pre-B cell growth.
1992
Expression and functional role of the proto-oncogene c-kit in acute myeloblastic leukemia cells
1991
Clinical Effect of Granulocyte Colony-stimulating Factor on Neutrophils and Leukemic Cells in Myelogenous Leukemia: Analysis
1991