Citation Impact
Citing Papers
In Melanoma, RAS Mutations Are Accompanied by Switching Signaling from BRAF to CRAF and Disrupted Cyclic AMP Signaling
2006
Differential Enhancement of Breast Cancer Cell Motility and Metastasis by Helical and Kinase Domain Mutations of Class IA Phosphoinositide 3-Kinase
2009
The Structure of a Human p110α/p85α Complex Elucidates the Effects of Oncogenic PI3Kα Mutations
2007 Science
Elevated CRAF as a Potential Mechanism of Acquired Resistance to BRAF Inhibition in Melanoma
2008
Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents
2012
Atorvastatin and fluvastatin are associated with dose‐dependent reductions in cirrhosis and hepatocellular carcinoma, among patients with hepatitis C virus: Results from ERCHIVES
2016
Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities
2022 Standout
Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF
2010
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
PIK3CA Mutations and Copy Number Gains in Human Lung Cancers
2008
The Regulation of Class IA PI 3-Kinases by Inter-Subunit Interactions
2010
Trametinib (GSK1120212) in the treatment of melanoma
2013
Differential expression of perforin in muscle-infiltrating T cells in polymyositis and dermatomyositis.
1996
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
1995 StandoutNobel
Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
2014 Standout
Body Fatness and Cancer — Viewpoint of the IARC Working Group
2016 Standout
Hepatocellular carcinoma
2018 Standout
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Guilty as charged
2004
Sam68 Allows Selective Targeting of Human Cancer Stem Cells
2017
Excess body weight and the risk of primary liver cancer: An updated meta-analysis of prospective studies
2012
Lung Cancer
2008 Standout
Liver Stiffness Is Associated With Risk of Decompensation, Liver Cancer, and Death in Patients With Chronic Liver Diseases: A Systematic Review and Meta-analysis
2013
Hallmarks of aging: An expanding universe
2023 Standout
Risk Assessment of Hepatitis B Virus–Related Hepatocellular Carcinoma Development Using Liver Stiffness Measurement (FibroScan) σ
2010
WNT Signaling in Cardiac and Vascular Disease
2017
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
2010 StandoutNature
Evidence-Based Diagnosis, Staging, and Treatment of Patients With Hepatocellular Carcinoma
2016
Oncogenic PI3K and its role in cancer
2005
Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF
2004 Standout
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
2015 Standout
Targeting phosphoinositide 3-kinase—Moving towards therapy
2007
Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity
2015 Standout
Colorectal cancer
2019 Standout
Comparative 13-year meta-analysis of the sensitivity and positive predictive value of ultrasound, CT, and MRI for detecting hepatocellular carcinoma
2015
Epidemiology and natural history of HCV infection
2013
Wnt signaling pathway in aging-related tissue fibrosis and therapies
2020
Long-term Therapeutic Outcomes of Radiofrequency Ablation for Subcapsular versus Nonsubcapsular Hepatocellular Carcinoma: A Propensity Score Matched Study
2016
Non-alcoholic fatty liver disease
2021 Standout
TSC2 regulates VEGF through mTOR-dependent and -independent pathways
2003 StandoutNobel
Are Patients with Child’s A Cirrhosis and Hepatocellular Carcinoma Appropriate Candidates for Liver Transplantation?
2011
Nonalcoholic Fatty Liver Disease and Hepatocellular Carcinoma: A Weighty Connection
2010
Inhibition of β-Catenin Signaling in the Skin Rescues Cutaneous Adipogenesis in Systemic Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Trial of C-82
2017
Structure of the Novel C-terminal Domain of Vacuolar Protein Sorting 30/Autophagy-related Protein 6 and Its Specific Role in Autophagy
2012 StandoutNobel
Hemodynamic Shear Stress and Its Role in Atherosclerosis
1999 Standout
Expression of mRNA for cyclooxygenase‐1 and cyclooxygenase‐2 in human tissues
1993
Punica granatum (pomegranate) and its potential for prevention and treatment of inflammation and cancer
2006 Standout
Prediction of posthepatectomy liver failure based on liver stiffness measurement in patients with hepatocellular carcinoma
2015
The emerging mechanisms of isoform-specific PI3K signalling
2010
Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
2008 Standout
Assessment of portal hypertension by transient elastography in patients with compensated cirrhosis and potentially resectable liver tumors
2011
Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)
1996 Standout
TGFβ in Cancer
2008 Standout
Atherosclerosis — An Inflammatory Disease
1999 Standout
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
1995 StandoutNobel
Wild-Type and Mutant B-RAF Activate C-RAF through Distinct Mechanisms Involving Heterodimerization
2005
Mammalian COP9 signalosome
2009
Surveillance Imaging and Alpha Fetoprotein for Early Detection of Hepatocellular Carcinoma in Patients With Cirrhosis: A Meta-analysis
2018
Prognostic Value of Controlled Attenuation Parameter by Transient Elastography
2017
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
AKT/PKB Signaling: Navigating the Network
2017 Standout
Inhibition of Mutated, Activated BRAF in Metastatic Melanoma
2010 Standout
PPM1A Functions as a Smad Phosphatase to Terminate TGFβ Signaling
2006
Stress-activated Protein Kinases (JNK and p38/HOG) Are Essential for Vascular Endothelial Growth Factor mRNA Stability
2000
The PI3K Pathway in Human Disease
2017 Standout
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
FGF Signaling and the Anterior Neural Induction in Xenopus
1999
Polymyositis and dermatomyositis
2003 Standout
Surveillance for hepatocellular carcinoma
2016
Elucidation of a Universal Size-Control Mechanism in Drosophila and Mammals
2007 Standout
Tumor Necrosis Factor Inhibits Spread of Hepatitis C Virus Among Liver Cells, Independent From Interferons
2017 StandoutNobel
Hepatocellular carcinoma
2022 Standout
Oncogenic PI3K deregulates transcription and translation
2005
Gatekeeper Mutations Mediate Resistance to BRAF-Targeted Therapies
2010
Hepatocellular Carcinoma
2019 Standout
PIK3CA Gene Mutations in Pediatric and Adult Glioblastoma Multiforme
2006
Inflammatory Muscle Diseases
2015 Standout
Increased Uncoupling Protein-2 Levels in β-cells Are Associated With Impaired Glucose-Stimulated Insulin Secretion
2001
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Functional Nanomaterials for Phototherapies of Cancer
2014 Standout
Uses for JNK: the Many and Varied Substrates of the c-Jun N-Terminal Kinases
2006
Liver stiffness measurement as an alternative to fibrotic stage in risk assessment of hepatocellular carcinoma incidence for chronic hepatitis C patients
2013
eFGF and its mode of action in the community effect during Xenopus myogenesis
2001 StandoutNobel
Cancer-specific mutations in PIK3CA are oncogenic in vivo
2006
NaN, a novel voltage-gated Na channel, is expressed preferentially in peripheral sensory neurons and down-regulated after axotomy
1998
Mitochondrial Dysfunction and Type 2 Diabetes
2005 StandoutScience
Liver Fibrosis: Mechanistic Concepts and Therapeutic Perspectives
2020
Cancer Genome Landscapes
2013 StandoutScience
Transforming properties of YAP , a candidate oncogene on the chromosome 11q22 amplicon
2006
Human Fatty Liver Disease: Old Questions and New Insights
2011 StandoutScience
Cancer-derived mutations in the regulatory subunit p85α of phosphoinositide 3-kinase function through the catalytic subunit p110α
2010
Long-term survival following a single treatment of kidney tumors with multiwalled carbon nanotubes and near-infrared radiation
2009
EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma
2018 Standout
Fluid Shear Stress Increases the Production of Granulocyte-Macrophage Colony-Stimulating Factor by Endothelial Cells via mRNA Stabilization
1998
Effect of Probucol Treatment on Gene Expression of VCAM-1, MCP-1, and M-CSF in the Aortic Wall of LDL Receptor–Deficient Rabbits During Early Atherogenesis
1997
Predicting Liver-Related Events Using Transient Elastography in Chronic Hepatitis C Patients with Sustained Virological Response
2015
Mechanism of Two Classes of Cancer Mutations in the Phosphoinositide 3-Kinase Catalytic Subunit
2007 Science
Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3)
2011 StandoutNobel
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Prognostic Role of KRAS and BRAF in Stage II and III Resected Colon Cancer: Results of the Translational Study on the PETACC-3, EORTC 40993, SAKK 60-00 Trial
2009
Alterations in components of the TGF-β superfamily signaling pathways in human cancer
2005
Fast detection of liver fibrosis with collagen-binding single-nanometer iron oxide nanoparticles via T 1 -weighted MRI
2023 StandoutNobel
Imaging Techniques for the Diagnosis of Hepatocellular Carcinoma
2015
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
EGF receptor gene mutations are common in lung cancers from “never smokers” and are associated with sensitivity of tumors to gefitinib and erlotinib
2004 Standout
Works of Jun Imamura being referenced
Ultrasound surveillance for early detection of hepatocellular carcinoma among patients with chronic hepatitis C
2009
Inhibition of Cyclic Adenosine Monophosphate (cAMP)-response Element-binding Protein (CREB)-binding Protein (CBP)/β-Catenin Reduces Liver Fibrosis in Mice
2015
Neoplastic Seeding After Radiofrequency Ablation for Hepatocellular Carcinoma
2008
Prospective risk assessment for hepatocellular carcinoma development in patients with chronic hepatitis C by transient elastography†
2009
Dietary effect of pomegranate seed oil on immune function and lipid metabolism in mice
2005
Safety, Tolerability, and Preliminary Efficacy of the Anti-Fibrotic Small Molecule PRI-724, a CBP/β-Catenin Inhibitor, in Patients with Hepatitis C Virus-related Cirrhosis: A Single-Center, Open-Label, Dose Escalation Phase 1 Trial
2017
Smad4 silencing in pancreatic cancer cell lines using stable RNA interference and gene expression profiles induced by transforming growth factor-β
2004
The hepatitis B virus X protein enhances AP-1 activation through interaction with Jab1
2005
Quantification of gene expression over a wide range by the polymerase chain reaction
1992
Treatment strategy for hepatocellular carcinoma: expanding the indications for radiofrequency ablation
2009
Obesity Is an Independent Risk Factor for Hepatocellular Carcinoma Development in Chronic Hepatitis C Patients
2008
Characterization of adenosine‐uridine‐rich RNA binding factors
1995
Value of post-vascular phase (Kupffer imaging) by contrast-enhanced ultrasonography using Sonazoid in the detection of hepatocellular carcinoma
2011
Functional analysis of mutations within the kinase activation segment of B-Raf in human colorectal tumors.
2003
Functional Analysis of PIK3CA Gene Mutations in Human Colorectal Cancer
2005
Different Effects of Point Mutations within the B-Raf Glycine-Rich Loop in Colorectal Tumors on Mitogen-Activated Protein/Extracellular Signal-Regulated Kinase Kinase/Extracellular Signal-Regulated Kinase and Nuclear Factor κB Pathway and Cellular Transformation
2004