Citation Impact
Citing Papers
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy
2022 StandoutNobel
Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION study
2009
Re-establishing immunological self-tolerance in autoimmune disease
2012 StandoutNobel
Design of effective immunotherapy for human autoimmunity
2005 Nature
Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia
2013 Standout
Targeting Interleukin-6 Signaling in Clinic
2019
Interleukin 6: from bench to bedside
2006
Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards
2016 Standout
New therapies for treatment of rheumatoid arthritis
2007
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
2012 StandoutNature
Interpreting lipid levels in the context of high-grade inflammatory states with a focus on rheumatoid arthritis: a challenge to conventional cardiovascular risk actions
2009
Rheumatoid arthritis
2016 Standout
Targeted Disruption of Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts
1997 Standout
Anti-TNF therapy: Where have we got to in 2005?
2005
Blockade of the interleukin‐21/interleukin‐21 receptor pathway ameliorates disease in animal models of rheumatoid arthritis
2007
Interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose homeostasis
2006
Thymus, innate immunity and autoimmune arthritis: Interplay of gene and environment
2011 StandoutNobel
Synthetic Molecular Motors and Mechanical Machines
2006 Standout
Delivery of nanomedicines to extracellular and intracellular compartments of a solid tumor
2011
Juvenile idiopathic arthritis
2007 Standout
Physiology and immunology of the cholinergic antiinflammatory pathway
2007 Standout
IL‐6: Regulator of Treg/Th17 balance
2010 Standout
Interleukin‐6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses
2008
Highly selective deuteration of pharmaceutically relevant nitrogen-containing heterocycles: a flow chemistry approach
2010
MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes
1998 Standout
The Pathogenesis of Rheumatoid Arthritis
2011 Standout
The IL-6/sIL-6R complex as a novel target for therapeutic approaches
2007
Osteoarthritis
2015 Standout
ESDN, a Novel Neuropilin-like Membrane Protein Cloned from Vascular Cells with the Longest Secretory Signal Sequence among Eukaryotes, Is Up-regulated after Vascular Injury
2001 StandoutNobel
Type 2 diabetes as an inflammatory disease
2011 Standout
Developmental regulation of the growth plate
2003 StandoutNature
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation
1999 Standout
Adipokines in inflammation and metabolic disease
2011 Standout
Identification of Putative Target Genes of the Transcription Factor RUNX2
2013 StandoutNobel
Interleukin-17 and Type 17 Helper T Cells
2009 Standout
Graves' Ophthalmopathy
2010 Standout
Beneficial health effects of exercise – the role of IL-6 as a myokine
2007
The discoidin domain family revisited: New members from prokaryotes and a homology‐based fold prediction
1998
Ankylosing spondylitis
2007 Standout
The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation
2002 Standout
Evidence that cytokines play a role in rheumatoid arthritis
2008
Foxp3: a genetic foundation for regulatory T cell differentiation and function
2020 StandoutNobel
Interleukin-6: discovery of a pleiotropic cytokine.
2006
Animal models of arthritis caused by systemic alteration of the immune system
2005 StandoutNobel
Stereochemical relays: communication via conformation
2006
Advanced glycation end products induce the expression of interleukin-6 and interleukin-8 by receptor for advanced glycation end product-mediated activation of mitogen-activated protein kinases and nuclear factor- B in human osteoarthritis chondrocytes
2010
Rheumatic diseases: the effects of inflammation on bone
2005
Physiological roles of muscle-derived interleukin-6 in response to exercise
2007
Tocilizumab, a humanized anti-interleukin-6 receptor antibody, improved anemia in monkey arthritis by suppressing IL-6-induced hepcidin production
2009
Tocilizumab for the Treatment of Steroid Refractory Graft-versus-Host Disease
2011
The Proportion of Regulatory T Cells in Patients with Rheumatoid Arthritis: A Meta-Analysis
2016 StandoutNobel
Mechanisms of Bone Metastasis
2004 Standout
How cells read TGF-β signals
2000 Standout
Synovial mast cells: role in acute and chronic arthritis
2007
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
2014 Standout
TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders
2000 Standout
Integrative biomarker analyses indicate etiological variations in hepatocellular carcinoma
2016
Cancer-related inflammation
2008 StandoutNature
Insulin resistance in patients with rheumatoid arthritis: effect of anti‐TNFα therapy
2007
Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial
2008
Arthritis and pneumonitis produced by the same T cell clones from mice with spontaneous autoimmune arthritis
2008 StandoutNobel
Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6
2008 Standout
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
Treg cell-based therapies: challenges and perspectives
2019
Anemia of Chronic Disease
2005 Standout
Hepatocellular carcinoma
2022 Standout
Interleukin-6 Signaling in Liver-Parenchymal Cells Suppresses Hepatic Inflammation and Improves Systemic Insulin Action
2010
Role of cytokines in rheumatoid arthritis: an education in pathophysiology and therapeutics
2008
Anti‐IL ‐6 receptor mA b eliminates myeloid‐derived suppressor cells and inhibits tumor growth by enhancing T ‐cell responses
2012
Current concepts in the diagnosis and management of cytokine release syndrome
2014 Standout
Targeting the interleukin‐6 receptor: A new treatment for systemic juvenile idiopathic arthritis?
2005
Comprehensive Evaluation of Different T-Helper Cell Subsets Differentiation and Function in Rheumatoid Arthritis
2012
Myocardial Fatty Acid Metabolism in Health and Disease
2010 Standout
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
The biological roles of exercise-induced cytokines: IL-6, IL-8, and IL-15
2007
IL-17 and Th17 Cells
2009 Standout
Toward simpler and faster genome-wide mutagenesis in mice
2007 StandoutNobel
INTERLEUKIN-6: From Basic Science to Medicine—40 Years in Immunology
2004
Cytokine Storm
2020 Standout
Mechanisms and pathologic significances in increase in serum interleukin-6 (IL-6) and soluble IL-6 receptor after administration of an anti–IL-6 receptor antibody, tocilizumab, in patients with rheumatoid arthritis and Castleman disease
2008
Artificial Molecular Machines
2015 Standout
Influence of .BETA.-Adrenoceptor Blockade on the Myocardial Accumulation of Fatty Acid Tracer and Its Intracellular Metabolism in the Heart After Ischemia-Reperfusion Injury
2006
Graded Attenuation of TCR Signaling Elicits Distinct Autoimmune Diseases by Altering Thymic T Cell Selection and Regulatory T Cell Function
2010 StandoutNobel
Satellite Cells and the Muscle Stem Cell Niche
2013 Standout
Role of myokines in exercise and metabolism
2007
gp130 at the nexus of inflammation, autoimmunity, and cancer
2010
The anti-inflammatory effect of exercise
2005 Standout
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Works of Jun Hashimoto being referenced
Clinical impact of c-Met expression and its gene amplification in hepatocellular carcinoma
2012
Biodistribution of immunoliposome labeled with Tc-99m in tumor xenografted mice
2009
Scintigraphic evaluation of myocardial ischaemia using a new fatty acid analogue: iodine-123-labelled 15-( p -iodophenyl)-9-( R , S )-methylpentadecanoic acid (9MPA)
1999
Expression of mRNA of murine bone-related proteins in ectopic bone induced by murine bone morphogenetic protein-4
1994
A cDNA Cloning of Human AEBP1 from Primary Cultured Osteoblasts and Its Expression in a Differentiating Osteoblastic Cell Line
1996
Treatment of rheumatoid arthritis with humanized anti–interleukin‐6 receptor antibody: A multicenter, double‐blind, placebo‐controlled trial
2004
Stereoselective synthesis of (2S,3S,4R,5S)-proline-3,4,5-d3
1997