Citation Impact
Citing Papers
Effective treatment of severe COVID-19 patients with tocilizumab
2020 Standout
Spontaneous Large-Scale Lymphoid Neogenesis and Balanced Autoimmunity versus Tolerance in the Stomach of H+/K+-ATPase-Reactive TCR Transgenic Mouse
2006 StandoutNobel
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Differential expression of chemokine receptors on peripheral blood B cells from patients with rheumatoid arthritis and systemic lupus erythematosus
2005
IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial
2008
Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION study
2009
The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis
2010 Standout
New insights into T cell biology and T cell‐directed therapy for autoimmunity, inflammation, and immunosuppression
2010
Activation-Induced Cytidine Deaminase Deficiency Causes Organ-Specific Autoimmune Disease
2008
Macrophages and their products in rheumatoid arthritis
2007
Current evidence for the management of rheumatoid arthritis with biological disease-modifying antirheumatic drugs: a systematic literature review informing the EULAR recommendations for the management of RA
2010
Targeting Interleukin-6 Signaling in Clinic
2019
Continued inhibition of structural damage over 2 years in patients with rheumatoid arthritis treated with rituximab in combination with methotrexate
2010
The B-Cell System in Inflammatory Bowel Disease
2006
Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies
2009
Sjögren's syndrome
2005 Standout
New therapies for treatment of rheumatoid arthritis
2007
Interpreting lipid levels in the context of high-grade inflammatory states with a focus on rheumatoid arthritis: a challenge to conventional cardiovascular risk actions
2009
Rheumatoid arthritis
2016 Standout
Targeted Disruption of Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts
1997 Standout
Role of Transforming Growth Factor β in Human Disease
2000 Standout
Associations of CTX-II with biochemical markers of bone turnover raise questions on its tissue origin: data from CHECK, a cohort study of early osteoarthritis
2012
Rheumatoid fibroblast‐like synoviocytes overexpress the chemokine stromal cell–derived factor 1 (CXCL12), which supports distinct patterns and rates of CD4+ and CD8+ T cell migration within synovial tissue
2003
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Expression of indian hedgehog, bone morphogenetic protein 6 and gli during skeletal morphogenesis1This work was presented in part at the 43rd Annual Meeting of the Orthopaedic Research Society, San Francisco, CA, February 1997.1
1997
Chemokines and their receptors in rheumatoid arthritis: Future targets?
2005
Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial
2013
Dorsoventral Patterning in Xenopus: Inhibition of Ventral Signals by Direct Binding of Chordin to BMP-4
1996 Standout
Patterns of FGF-23, DMP1, and MEPE expression in patients with chronic kidney disease
2009
Estrogen receptor α is a major mediator of 17β-estradiol’s atheroprotective effects on lesion size in Apoe–/– mice
2001 StandoutNobel
Expression of the B Cell‐Attracting Chemokine CXCL13 in the Target Organ and Autoantibody Production in Ectopic Lymphoid Tissue in the Chronic Inflammatory Disease Sjögren's Syndrome
2002
MEPE expression in osteocytes during orthodontic tooth movement
2007
Lymphangiogenesis: Molecular Mechanisms and Future Promise
2010 Standout
Cbfa1, a Candidate Gene for Cleidocranial Dysplasia Syndrome, Is Essential for Osteoblast Differentiation and Bone Development
1997 Standout
Colony-stimulating factors in inflammation and autoimmunity
2008
MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes
1998 Standout
Interleukin‐6 receptor inhibition with tocilizumab reduces disease activity in rheumatoid arthritis with inadequate response to disease‐modifying antirheumatic drugs: The tocilizumab in combination with traditional disease‐modifying antirheumatic drug therapy study
2008
The biology of VEGF and its receptors
2003 Standout
Mutations Involving the Transcription Factor CBFA1 Cause Cleidocranial Dysplasia
1997 Standout
The Pathogenesis of Rheumatoid Arthritis
2011 Standout
Osteoarthritis
2015 Standout
How antirheumatic drugs protect joints from damage in rheumatoid arthritis
2008
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
ABA-triblock copolymers from biodegradable polyester A-blocks and hydrophilic poly(ethylene oxide) B-blocks as a candidate for in situ forming hydrogel delivery systems for proteins
2002
Lymphoid organ development: from ontogeny to neogenesis
2006
Graves' Ophthalmopathy
2010 Standout
Biomaterial developments for bone tissue engineering
2000 Standout
Crohn's disease
2016 Standout
Toward a molecular understanding of skeletal development
1995
Expression of mRNA of murine bone-related proteins in ectopic bone induced by murine bone morphogenetic protein-4
1994
Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis
2006
Hypoxia and TGF-β Drive Breast Cancer Bone Metastases through Parallel Signaling Pathways in Tumor Cells and the Bone Microenvironment
2009
Combination of Bone Marrow and TGF-β1 Augment the Healing of Critical-Sized bone Defects
1998
IL‐1, IL‐18, and IL‐33 families of cytokines
2008
Identification of osteocyte‐selective proteins
2010
Updated consensus statement on biological agents for the treatment of rheumatic diseases, 2010
2011 Standout
Bone Morphogenetic Proteins: From Basic Studies to Clinical Approaches
1998
Enhanced Activation of Memory, but Not Naïve, B Cells in Chronic Hepatitis C Virus-Infected Patients with Cryoglobulinemia and Advanced Liver Fibrosis
2013 StandoutNobel
Origin and physiological roles of inflammation
2008 StandoutNature
Mechanisms of fatty acid-induced inhibition of glucose uptake.
1994 Standout
Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells
2009 StandoutNature
Lymphoid neogenesis in chronic inflammatory diseases
2006
IgG4-related disease
2014 Standout
Immunological functions of leptin and adiponectin
2012
What We Talk About When We Talk About Fat
2014 Standout
Buried alive: How osteoblasts become osteocytes
2005
On the mechanisms of biocompatibility
2008 Standout
The AMBITION trial: tocilizumab monotherapy for rheumatoid arthritis
2010
Extracellular Matrix-Associated Bone Morphogenetic Proteins Are Essential for Differentiation of Murine Osteoblastic Cellsin Vitro1
1999
Mast cells in the pathogenesis of rheumatic diseases and as potential targets for anti‐rheumatic therapy
2007
Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial
2008
Exploring the full spectrum of macrophage activation
2008 Standout
Macrophysiologic Roles of a Delivery System for Vulnerary Factors Needed for Bone Regeneration
1997
Healing Bone Using Recombinant Human Bone Morphogenetic Protein 2 and Copolymer
1998
Bifidobacteria can protect from enteropathogenic infection through production of acetate
2011 StandoutNature
The efficacy and safety of reinstitution of tocilizumab in patients with relapsed active rheumatoid arthritis after long-term withdrawal of tocilizumab
2011
The Many Roles of Chemokines and Chemokine Receptors in Inflammation
2006 Standout
Fibroblast-Like Synoviocytes of Mesenchymal Origin Express Functional B Cell-Activating Factor of the TNF Family in Response to Proinflammatory Cytokines
2005
Use of monoclonal antibody to detect bone morphogenetic protein-4 (BMP-4)
1995
AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements
2007 StandoutNobel
Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4
2010
Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover
2002
Adipokines in Arthritis: New Kids on the Block
2009
Phosphorylated Proteins and Control over Apatite Nucleation, Crystal Growth, and Inhibition
2008
Polymeric Systems for Controlled Drug Release
1999 Standout
Cellular Interactions in Lymph Node Development
2005
Sustained release emphasizing recombinant human bone morphogenetic protein-2
1998
PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice
2011 StandoutNobel
Plasma chemokine levels correlate with the outcome of antiviral therapy in patients with hepatitis C
2005 StandoutNobel
Hydrogels for Tissue Engineering
2001 Standout
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Synthesis, Characterization, and Hydrolytic Degradation of PLA/PEO/PLA Triblock Copolymers with Short Poly(l -lactic acid) Chains
1996
Description of the Efficacy and Safety of Three New Biologics in the Treatment of Rheumatoid Arthritis
2010
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Calcifying Subpopulation of Bovine Aortic Smooth Muscle Cells Is Responsive to 17β-Estradiol
1997
Cytokine Storm
2020 Standout
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
CSF-1–Dependent Red Pulp Macrophages Regulate CD4 T Cell Responses
2011 StandoutNobel
Polydopamine and Its Derivative Materials: Synthesis and Promising Applications in Energy, Environmental, and Biomedical Fields
2014 Standout
Efficacy of tocilizumab and evaluation of clinical remission as determined by CDAI and MMP-3 level
2009
Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy
2009
T Follicular Helper (TFH) Cells in Normal and Dysregulated Immune Responses
2008
Interaction between Synovial Inflammatory Tissue and Bone Marrow in Rheumatoid Arthritis
2005
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
The amazing osteocyte
2010 Standout
NF-κB-Inducing Kinase Regulates Selected Gene Expression in the Nod2 Signaling Pathway
2006
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Immediate reduction of white blood cell count after tocilizumab administration was observed in some cases
2009
Extracellular Matrix-Associated Bone Morphogenetic Proteins Are Essential for Differentiation of Murine Osteoblastic Cells in Vitro
1999
Hypoxia‐inducible factor regulates osteoclast‐mediated bone resorption: role of angiopoietin‐like 4
2010
Osteoarthritis: an update with relevance for clinical practice
2011 Standout
Mice lacking tartrate-resistant acid phosphatase (Acp 5) have disrupted endochondral ossification and mild osteopetrosis
1996 StandoutNobel
Regulation of Rate of Cartilage Differentiation by Indian Hedgehog and PTH-Related Protein
1996 StandoutScience
Chemokines in Innate and Adaptive Host Defense : Basic Chemokinese Grammar for Immune Cells
2004
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Works of Jun Hashimoto being referenced
Laboratory and febrile features after joint surgery in patients with rheumatoid arthritis treated with tocilizumab
2008
Nurse‐like cells from patients with rheumatoid arthritis support the survival of osteoclast precursors via macrophage colony‐stimulating factor production
2005
Preservation of ectopically induced bone in the mouse by estradiol
1991
Cartilage repair using an in vitro generated scaffold-free tissue-engineered construct derived from porcine synovial mesenchymal stem cells
2007
Adiponectin increases bone mass by suppressing osteoclast and activating osteoblast
2005
Imatinib mesylate inhibits osteoclastogenesis and joint destruction in rats with collagen-induced arthritis (CIA)
2006
Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab
2007
Oxygen tension is an important mediator of the transformation of osteoblasts to osteocytes
2007
Serum adiponectin concentrations correlate with severity of rheumatoid arthritis evaluated by extent of joint destruction
2008
Antiangiogenic Agent (TNP-470) Inhibition of Ectopic Bone Formation Induced by Bone Morphogenetic Protein-2
1998
Matrix extracellular phosphoglycoprotein (MEPE) is highly expressed in osteocytes in human bone
2004
Adenovirus-mediated gene transfer of adiponectin reduces the severity of collagen-induced arthritis in mice
2008
A combination of biochemical markers of cartilage and bone turnover, radiographic damage and body mass index to predict the progression of joint destruction in patients with rheumatoid arthritis treated with disease-modifying anti-rheumatic drugs
2009
Lymphoid Chemokine B Cell-Attracting Chemokine-1 (CXCL13) Is Expressed in Germinal Center of Ectopic Lymphoid Follicles Within the Synovium of Chronic Arthritis Patients
2001
Polylactic Acid-Polyethylene Glycol Block Copolymer
1993
Transient and localized expression of bone morphogenetic protein 4 messenger RNA during fracture healing
1994
A combination of biochemical markers of cartilage and bone turnover, radiographic damage and body mass index to predict the progression of joint destruction in patients with rheumatoid arthritis treated with disease-modifying anti-rheumatic drugs
2009
Evaluation of Polylactic Acid Homopolymers as Carriers for Bone Morphogenetic Protein
1992
Purification and Characterization of a Bone-Inducing Protein From a Murine Osteosarcoma (Dunn Type)
1993