Citation Impact
Citing Papers
Visualizing enveloping layer glycans during zebrafish early embryogenesis
2010 StandoutNobel
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
Design and Synthesis of Highly Reactive Dienophiles for the Tetrazine– trans- Cyclooctene Ligation
2011
Copper-free click chemistry in living animals
2010 StandoutNobel
Efficient production of [ n ]rotaxanes by using template-directed clipping reactions
2007 StandoutNobel
Chemical strategies for tagging and imaging the proteome
2011
Azide: A Unique Dipole for Metal‐Free Bioorthogonal Ligations
2010
Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging
2008
Bioorthogonal chemistry: recent progress and future directions
2010
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Donor–Acceptor Oligorotaxanes Made to Order
2011 StandoutNobel
Imaging beyond the proteome
2012 StandoutNobel
Fast, Cell‐Compatible Click Chemistry with Copper‐Chelating Azides for Biomolecular Labeling
2012
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Genetically Encoded Copper‐Free Click Chemistry
2011
One pot ‘click’ reactions: tandem enantioselective biocatalytic epoxide ring opening and [3+2] azide alkyne cycloaddition
2010 StandoutNobel
Reliable and Efficient Procedures for the Conjugation of Biomolecules through Huisgen Azide–Alkyne Cycloadditions
2011
Synthetic Approaches to a Molecular Borromean Link: Two‐Ring Threading with Polypyridine Templates
2003
Donor–Acceptor Ring‐in‐Ring Complexes
2011 StandoutNobel
Crosslinking Studies of Protein-Protein Interactions in Nonribosomal Peptide Biosynthesis
2009 StandoutNobel
Selective Fluorescence Labeling of Lipids in Living Cells
2009
Cyclooctyne-based reagents for uncatalyzed click chemistry: A computational survey
2009
Nitrones as dipoles for rapid strain-promoted 1,3-dipolar cycloadditions with cyclooctynes
2009
Membrane labeling and immobilization viacopper-free click chemistry
2011
Activity based subcellular resolution imaging of lipases
2011
Visualizing specific protein glycoforms by transmembrane fluorescence resonance energy transfer
2012
Dynamic covalent templated-synthesis of [c2]daisy chains
2012 StandoutNobel
Template synthesis of molecular knots
2012
Topologically Chiral Covalent Assemblies of Molecular Knots with Linear, Branched, and Cyclic Architectures
2004
Directed self-assembly of a ring-in-ring complex
2010 StandoutNobel
Bioorthogonal chemistry: strategies and recent developments
2013
Fast and Sensitive Pretargeted Labeling of Cancer Cells through a Tetrazine/ trans ‐Cyclooctene Cycloaddition
2009
Azobenzene Photoswitches for Staudinger–Bertozzi Ligation
2013 StandoutNobel
Lithium‐Templated Synthesis of a Donor–Acceptor Pseudorotaxane and Catenane
2004
Synthesis of a metal-free coordinating ring via formation of a cleavable [2]catenane
2013 StandoutNobel
Genetic Encoding of a Bicyclo[6.1.0]nonyne‐Charged Amino Acid Enables Fast Cellular Protein Imaging by Metal‐Free Ligation
2012
New Molecular Topologies by Fourfold Metathesis Reactions within a Hydrogen‐Bonded Calix[4]arene Dimer
2003
Surface Functionalization by Strain‐Promoted Alkyne–Azide Click Reactions
2011
Increasing the Efficacy of Bioorthogonal Click Reactions for Bioconjugation: A Comparative Study
2011
Imaging the Glycome in Living Systems
2012
Bioorthogonal labelling of biomolecules: new functional handles and ligation methods
2013
Triply interlocked covalent organic cages
2010
Click Chemistry beyond Metal‐Catalyzed Cycloaddition
2009
Strain‐Promoted Copper‐Free “Click” Chemistry for 18F Radiolabeling of Bombesin
2011 StandoutNobel
Fast copper-free click DNA ligation by the ring-strain promoted alkyne-azide cycloaddition reaction
2011
Readily Accessible Bicyclononynes for Bioorthogonal Labeling and Three‐Dimensional Imaging of Living Cells
2010
Active‐Metal Template Synthesis of a Molecular Trefoil Knot
2011
Multi-molecule reaction of serum albumin can occur through thiol-yne coupling
2011
Strategies and Tactics for the Metal‐Directed Synthesis of Rotaxanes, Knots, Catenanes, and Higher Order Links
2011
Bioorthogonal Turn‐On Probes for Imaging Small Molecules inside Living Cells
2010
Clickable fluorophores for biological labeling—with or without copper
2009
Covalent Chemistry and Conformational Dynamics of Topologically Chiral Amide‐Based Molecular Knots
2003
Dual Labeling of Biomolecules by Using Click Chemistry: A Sequential Approach
2008
Chemoselective Ligation and Modification Strategies for Peptides and Proteins
2008
Template‐Directed Syntheses of Rigid Oligorotaxanes under Thermodynamic Control
2010 StandoutNobel
A BODIPY‐Cyclooctyne for Protein Imaging in Live Cells
2011
Glycan‐Specific Metabolic Oligosaccharide Engineering of C7‐Substituted Sialic Acids
2012
Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free (3+2) cycloaddition
2009
Chemical Approaches To Perturb, Profile, and Perceive Glycans
2009 StandoutNobel
The use of click chemistry in the emerging field of catalomics
2010
Knotaxanes—Rotaxanes with Knots as Stoppers
2003
Synthesis of a D3-symmetric “trefoil” knotted cyclophane
2011
Cu-free click cycloaddition reactions in chemical biology
2010 StandoutNobel
The Emergence of Thiol–Ene Coupling as a Click Process for Materials and Bioorganic Chemistry
2008
Imaging the Sialome during Zebrafish Development with Copper‐Free Click Chemistry
2012 StandoutNobel
Thiacycloalkynes for Copper‐Free Click Chemistry
2012 StandoutNobel
Development and evaluation of new cyclooctynes for cell surface glycan imaging in cancer cells
2011
A synthetic molecular pentafoil knot
2011
Live‐Cell Imaging of Cellular Proteins by a Strain‐Promoted Azide–Alkyne Cycloaddition
2010 StandoutNobel
Knotting and Threading of Molecules: Chemistry and Chirality of Molecular Knots and Their Assemblies
2005
Bringing chemistry to life
2011 StandoutNobel
Three‐Component Entanglements Consisting of Three Crescent‐Shaped Bidentate Ligands Coordinated to an Octahedral Metal Centre
2007
Reactivity of Biarylazacyclooctynones in Copper-Free Click Chemistry
2012 StandoutNobel
A Molecular Solomon Link
2006
Chemical probing of glycans in cells and organisms
2012
A Genetically Encoded Norbornene Amino Acid for the Mild and Selective Modification of Proteins in a Copper‐Free Click Reaction
2012
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
Stereoselective Synthesis of a Topologically Chiral Molecule: The Trefoil Knot
2004 StandoutNobel
Residual Topological Isomerism of Intertwined Molecules
2004
Fast Alkene Functionalization In Vivo by Photoclick Chemistry: HOMO Lifting of Nitrile Imine Dipoles
2009
Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity
2008
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Chemical Topology: Complex Molecular Knots, Links, and Entanglements
2011 StandoutNobel
Catenation through a Combination of Radical Templation and Ring-Closing Metathesis
2015 StandoutNobel
A New Doubly Interlocked [2]Catenane
2008
Genetic Encoding of Bicyclononynes and trans-Cyclooctenes for Site-Specific Protein Labeling in Vitro and in Live Mammalian Cells via Rapid Fluorogenic Diels–Alder Reactions
2012
A Hydrophilic Azacyclooctyne for Cu-Free Click Chemistry
2008 StandoutNobel
The Thread & Cut Method: Syntheses of Molecular Knot Precursors
2008
Spontaneous Knotting—From Oligoamide Threads to Trefoil Knots
2006
Polar Dibenzocyclooctynes for Selective Labeling of Extracellular Glycoconjugates of Living Cells
2012
Copper-Free “Click” Modification of DNA via Nitrile Oxide−Norbornene 1,3-Dipolar Cycloaddition
2009
Surpassing the Use of Copper in the Click Functionalization of Polymeric Nanostructures: A Strain-Promoted Approach
2009
Labeling Live Cells by Copper-Catalyzed Alkyne−Azide Click Chemistry
2010
Self-Assembly of a Metallomacrocycle Templated by Iron(II)
2010
Selektive Fluoreszenzmarkierung von Lipiden in lebenden Zellen
2009
From Mechanism to Mouse: A Tale of Two Bioorthogonal Reactions
2011 StandoutNobel
Zuverlässige und effiziente Konjugation von Biomolekülen über Huisgen‐Azid‐Alkin‐Cycloadditionen
2011
Bioorthogonal Chemistry: Applications in Activity-Based Protein Profiling
2011
Cellular Incorporation of Unnatural Amino Acids and Bioorthogonal Labeling of Proteins
2014
Pentameric Circular Iron(II) Double Helicates and a Molecular Pentafoil Knot
2012
Bioconjugation with Strained Alkenes and Alkynes
2011
Programmed assembly of 3-dimensional microtissues with defined cellular connectivity
2009 StandoutNobel
The atom, the molecule, and the covalent organic framework
2017 StandoutScienceNobel
Dynamic metabolic labeling of DNA in vivo with arabinosyl nucleosides
2011
Transition States of Strain-Promoted Metal-Free Click Chemistry: 1,3-Dipolar Cycloadditions of Phenyl Azide and Cyclooctynes
2008
Selective Labeling of Living Cells by a Photo-Triggered Click Reaction
2009
Click Chemistry and Bioorthogonal Reactions: Unprecedented Selectivity in the Labeling of Biological Molecules
2009
Developments in the Field of Bioorthogonal Bond Forming Reactions—Past and Present Trends
2014
Fluorophore Targeting to Cellular Proteins via Enzyme-Mediated Azide Ligation and Strain-Promoted Cycloaddition
2012 StandoutNobel
Difluorobenzocyclooctyne: Synthesis, Reactivity, and Stabilization by β-Cyclodextrin
2010 StandoutNobel
High‐Density DNA Functionalization by a Combination of Cu‐Catalyzed and Cu‐Free Click Chemistry
2010
The development of anticancer ruthenium(ii ) complexes: from single molecule compounds to nanomaterials
2017 Standout
Introducing Bioorthogonal Functionalities into Proteins in Living Cells
2011
Bioorthogonal Labeling of 5-Hydroxymethylcytosine in Genomic DNA and Diazirine-Based DNA Photo-Cross-Linking Probes
2011
Ravels: knot-free but not free. Novel entanglements of graphs in 3-space
2008
Imaging bacterial peptidoglycan with near-infrared fluorogenic azide probes
2014 StandoutNobel
Non-Nucleoside Building Blocks for Copper-Assisted and Copper-Free Click Chemistry for the Efficient Synthesis of RNA Conjugates
2010
Visualization of Protein‐Specific Glycosylation inside Living Cells
2016
Enzymatic construction of highly strained carbocycles
2018 StandoutScienceNobel
A Pictet-Spengler ligation for protein chemical modification
2012 StandoutNobel
A Ring-in-Ring Complex We thank Dr. Peter T. Glink, Dr. M. Jane Strouse, and Dr. Ping Yang for useful discussions and both the National Science Foundation and the Petroleum Research Fund, administered by the American Chemical Society, for generous financial support.
2002 StandoutNobel
Rapid Cu-Free Click Chemistry with Readily Synthesized Biarylazacyclooctynones
2010 StandoutNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Readily Accessible Bicyclononynes for Bioorthogonal Labeling and Three‐Dimensional Imaging of Living Cells
2010
The magic effect of endocyclic but non-sterically hindering biisoquinoline chelates: From fast-moving molecular shuttles to [3]rotaxanes
2009 StandoutNobel
Reactivity and Regioselectivity in 1,3-Dipolar Cycloadditions of Azides to Strained Alkynes and Alkenes: A Computational Study
2009
A [2]Catenane Constructed around a Ru(Diimine)32+ Complex Used as a Template
2003 StandoutNobel
A Bioorthogonal Quadricyclane Ligation
2011 StandoutNobel
Chemically tunable mucin chimeras assembled on living cells
2015 StandoutNobel
Molecular Borromean Rings
2004 StandoutScienceNobel
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Open Problems in Chemical Topology
2008
Chemoselektive Ligations‐ und Modifikationsstrategien für Peptide und Proteine
2008
Imaging the glycome
2008 StandoutNobel
Mechanical Bonds and Topological Effects in Radical Dimer Stabilization
2014 StandoutNobel
Biomedical Applications of Tetrazine Cycloadditions
2011
A Fluorogenic Probe for the Catalyst-Free Detection of Azide-Tagged Molecules
2012
Bioorthogonal Turn‐On Probes for Imaging Small Molecules inside Living Cells
2010
Functionalized Cyclopropenes As Bioorthogonal Chemical Reporters
2012
Discovery of an Organic Trefoil Knot
2012 Science
Topologically complex molecules obtained by transition metal templation: it is the presentation that determines the synthesis strategy
2012 StandoutNobel
Orthogonal bioorthogonal chemistries
2015
Synthesis of a Fluorogenic Cyclooctyne Activated by Cu-Free Click Chemistry
2011 StandoutNobel
Surface Functionalization Using Catalyst-Free Azide−Alkyne Cycloaddition
2010
Second-Generation Difluorinated Cyclooctynes for Copper-Free Click Chemistry
2008 StandoutNobel
Die Entwicklung der Thiol‐En‐Kupplung als Klick‐Prozess für die Materialwissenschaften und die bioorganische Chemie
2008
Mass Spectrometric Analysis of the Cell Surface N-Glycoproteome by Combining Metabolic Labeling and Click Chemistry
2014
Strain-Promoted “Click” Chemistry for Terminal Labeling of DNA
2011
Glycan Imaging in Intact Rat Hearts and Glycoproteomic Analysis Reveal the Upregulation of Sialylation during Cardiac Hypertrophy
2014
Real-Time Bioluminescence Imaging of Glycans on Live Cells
2010 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
Self-Assembly of a [2]Pseudorota[3]catenane in Water
2012 StandoutNobel
Application of copper(I)-catalysed azide/alkyne cycloaddition (CuAAC) ‘click chemistry’ in carbohydrate drug and neoglycopolymer synthesis
2010
Bioorthogonale Chemie – oder: in einem Meer aus Funktionalität nach Selektivität fischen
2009 StandoutNobel
Works of Jun Guo being referenced
Visualizing Metabolically Labeled Glycoconjugates of Living Cells by Copper‐Free and Fast Huisgen Cycloadditions
2008
Strain‐Promoted Alkyne–Azide Cycloadditions (SPAAC) Reveal New Features of Glycoconjugate Biosynthesis
2011
Protein Modification by Strain‐Promoted Alkyne–Nitrone Cycloaddition
2010
Knot tied around an octahedral metal centre
2001 Nature
Convergent Assembly and Surface Modification of Multifunctional Dendrimers by Three Consecutive Click Reactions
2010
Two-step bioorthogonal activity-based proteasome profiling using copper-free click reagents: A comparative study
2011
Surface Modification of Polymeric Micelles by Strain‐Promoted Alkyne–Azide Cycloadditions
2010
Synthesis of a molecular trefoil knot by folding and closing on an octahedral coordination template
2010
Multifunctional Surface Modification of Gold-Stabilized Nanoparticles by Bioorthogonal Reactions
2011
Metal-Free Sequential [3 + 2]-Dipolar Cycloadditions using Cyclooctynes and 1,3-Dipoles of Different Reactivity
2010
Protein Modification by Strain‐Promoted Alkyne–Nitrone Cycloaddition
2010
Visualizing Metabolically Labeled Glycoconjugates of Living Cells by Copper‐Free and Fast Huisgen Cycloadditions
2008