Standout Papers
Citation Impact
Citing Papers
Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains
2006
Lipid Rafts As a Membrane-Organizing Principle
2009 StandoutScience
Sterol structure determines the separation of phases and the curvature of the liquid-ordered phase in model membranes
2005
The identification and characterization of two phosphatidylinositol-4,5-bisphosphate 4-phosphatases
2005
Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons
2020 StandoutNobel
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
2012 StandoutScience
The HIV lipidome: A raft with an unusual composition
2006
Cargo sorting into multivesicular bodies in vitro
2009 StandoutNobel
Identification of nucleotide patterns enriched in secreted RNAs as putative cis-acting elements targeting them to exosome nano-vesicles
2011
Syndecan–syntenin–ALIX regulates the biogenesis of exosomes
2012
Exosomes and other extracellular vesicles in host–pathogen interactions
2014
Hijacking Multivesicular Bodies Enables Long-Term and Exosome-Mediated Long-Distance Action of Anthrax Toxin
2013
A GTPase-activating protein controls Rab5 function in endocytic trafficking
2005
IFITM3 Inhibits Influenza A Virus Infection by Preventing Cytosolic Entry
2011
Exosome lipidomics unravels lipid sorting at the level of multivesicular bodies
2006
Rab11 Promotes Docking and Fusion of Multivesicular Bodies in a Calcium‐Dependent Manner
2004
Autophagosomes form at ER–mitochondria contact sites
2013 StandoutNature
Extracellular vesicles round off communication in the nervous system
2016
Mesenchymal stem cell: An efficient mass producer of exosomes for drug delivery
2012
The Crystal Structure of the PX Domain from p40phox Bound to Phosphatidylinositol 3-Phosphate
2001
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Cellular lipidomics
2005
Exosomes: immune properties and potential clinical implementations
2010
Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu
2008 StandoutNature
Exosomes: A Common Pathway for a Specialized Function
2006
EGF stimulates annexin 1‐dependent inward vesiculation in a multivesicular endosome subpopulation
2005
RILP interacts with VPS22 and VPS36 of ESCRT-II and regulates their membrane recruitment
2006
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
ALIX and the multivesicular endosome: ALIX in Wonderland
2013
Multivesicular bodies: co-ordinated progression to maturity
2008
The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer
2018
Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy
2012
Separation and Characterization of Late Endosomal Membrane Domains
2002
Diacylglycerol kinase α regulates the formation and polarisation of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes
2011
Exosomes in the Diseased Brain: First Insights from In vivo Studies
2017
Noninvasive In Vivo Monitoring of Extracellular Vesicles
2013
Different Microtubule Motors Move Early and Late Endocytic Compartments
2008
p40 : The last NADPH oxidase subunit
2005
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
Oligodendrocytes secrete exosomes containing major myelin and stress‐protective proteins: Trophic support for axons?
2007
Exosomes: proteomic insights and diagnostic potential
2009
Piezo proteins are pore-forming subunits of mechanically activated channels
2012 StandoutNatureNobel
Retrovirus-like Gag Protein Arc1 Binds RNA and Traffics across Synaptic Boutons
2018
Intra-endosomal membrane traffic
2006
Cellular cholesterol trafficking and compartmentalization
2008
Nef Neutralizes the Ability of Exosomes from CD4+ T Cells to Act as Decoys during HIV-1 Infection
2014
Membrane scission by the ESCRT-III complex
2009 Nature
Mechanism of Evenness Interrupted (Evi)-Exosome Release at Synaptic Boutons
2012
Exosomes as new diagnostic tools in CNS diseases
2015
Biogenesis and secretion of exosomes
2014
Packaging of prions into exosomes is associated with a novel pathway of PrP processing
2007
p40 Down-regulates NADPH Oxidase Activity through Interactions with Its SH3 Domain
1997
A Protein's Final ESCRT
2004
Trans-Synaptic Transmission of Vesicular Wnt Signals through Evi/Wntless
2009
Membrane vesicles as conveyors of immune responses
2009 Standout
Syntenin-ALIX exosome biogenesis and budding into multivesicular bodies are controlled by ARF6 and PLD2
2014
Role of Exosomes/Microvesicles in the Nervous System and Use in Emerging Therapies
2012
Late Endosomal Cholesterol Accumulation Leads to Impaired Intra-Endosomal Trafficking
2007
Shedding light on the cell biology of extracellular vesicles
2018 Standout
ESCRT & Co
2010
Plasma Membrane Is the Site of Productive HIV-1 Particle Assembly
2006
Endocytosis of HIV-1 activates plasmacytoid dendritic cells via Toll-like receptor- viral RNA interactions
2005
Signaling from endosomes: Location makes a difference
2008
Exosomes go with the Wnt
2012
Evidence for secretion of Cu,Zn superoxide dismutase via exosomes from a cell model of amyotrophic lateral sclerosis
2007
Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson’s disease and dementia with Lewy bodies
2015
The ESCRT complexes
2010
MX2 is an interferon-induced inhibitor of HIV-1 infection
2013 StandoutNatureNobel
Multivesicular Endosome Biogenesis in the Absence of ESCRTs
2009
Acid sphingomyelinase activity triggers microparticle release from glial cells
2009
Structure of the mechanically activated ion channel Piezo1
2017 StandoutNatureNobel
New Insights into the Mechanisms of Macroautophagy in Mammalian Cells
2008
Release of exosomes from differentiated neurons and its regulation by synaptic glutamatergic activity
2010
The Role of LIP5 and CHMP5 in Multivesicular Body Formation and HIV-1 Budding in Mammalian Cells
2005
Exosomes – vesicular carriers for intercellular communication
2009 Standout
Virus Entry: Open Sesame
2006
Dynein is required for receptor sorting and the morphogenesis of early endosomes
2006
T Cell Receptor-Proximal Signals Are Sustained in Peripheral Microclusters and Terminated in the Central Supramolecular Activation Cluster
2006
Regulation of the V-ATPase along the Endocytic Pathway Occurs through Reversible Subunit Association and Membrane Localization
2008
Genetic, Biochemical, and Clinical Features of Chronic Granulomatous Disease
2000
Lysobisphosphatidic Acid Controls Endosomal Cholesterol Levels
2008
Exosomes as new vesicular lipid transporters involved in cell–cell communication and various pathophysiologies
2013
Multivesicular bodies in neurons: Distribution, protein content, and trafficking functions
2011
Amyloid precursor protein products concentrate in a subset of exosomes specifically endocytosed by neurons
2017
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
2016 StandoutNature
Membrane lipids: where they are and how they behave
2008 Standout
Extracellular vesicles – Their role in the packaging and spread of misfolded proteins associated with neurodegenerative diseases
2015
The 40‐kDa Component of the Phagocyte NADPH Oxidase (p40phox) is Phosphorylated during Activation in Differentiated HL60 Cells
1997
Membrane curvature and mechanisms of dynamic cell membrane remodelling
2005 StandoutNature
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
A Lumenal Domain-Dependent Pathway for Sorting to Intralumenal Vesicles of Multivesicular Endosomes Involved in Organelle Morphogenesis
2006
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
Endosome maturation
2011 Standout
Annexin A2-Dependent Polymerization of Actin Mediates Endosome Biogenesis
2009
Roles of Endogenously Synthesized Sterols in the Endocytic Pathway
2006
The cAMP Signaling Pathway has Opposing Effects on Rac and Rho in B16F10 Cells: Implications for Dendrite Formation in Melanocytic Cells
2003
Points of control in inflammation
2002 StandoutNature
Exosome Secretion: Molecular Mechanisms and Roles in Immune Responses
2011
Lysosomal degradation of membrane lipids
2009
Exosomes: Vehicles for the Transfer of Toxic Proteins Associated with Neurodegenerative Diseases?
2012
Powering membrane traffic in endocytosis and recycling
2006
Structural Basis for Endosomal Targeting by the Bro1 Domain
2005
Exosomes: Therapy delivery tools and biomarkers of diseases
2017
Ongoing activation of sphingosine 1-phosphate receptors mediates maturation of exosomal multivesicular endosomes
2013
The ESCRT Pathway
2011
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
Termination of autophagy and reformation of lysosomes regulated by mTOR
2010 StandoutNature
Are synucleinopathies prion-like disorders?
2010
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
The Complex Ultrastructure of the Endolysosomal System
2014
The biogenesis of multivesicular endosomes
2004
The emerging shape of the ESCRT machinery
2007
Extracellular vesicles: biology and emerging therapeutic opportunities
2013 Standout
Subcellular targeting strategies for drug design and delivery
2009
Cell-Produced α-Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival
2010
Autophagy in immunity and inflammation
2011 StandoutNature
Proteolipidic Composition of Exosomes Changes during Reticulocyte Maturation
2011
Emerging Role of Neuronal Exosomes in the Central Nervous System
2012
Extracellular Vesicles: How Drug and Pathology Interfere With Their Biogenesis and Function
2018
Neuron to glia signaling triggers myelin membrane exocytosis from endosomal storage sites
2006
A family of distal arthrogryposis type 5 due to a novel PIEZO2 mutation
2015
Extracellular vesicles: Exosomes, microvesicles, and friends
2013 Standout
Virus Entry by Endocytosis
2010
Rab7: roles in membrane trafficking and disease
2009
Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway
2004
The Late Endosome is Essential for mTORC1 Signaling
2010
Mesenchymal Stem Cell Exosome: a Novel Stem Cell-Based Therapy for Cardiovascular Disease
2011
NADPH Oxidase: An Update
1999 Standout
New Generation Adsorbents for Water Treatment
2012 Standout
Role for Rab7 in maturation of late autophagic vacuoles
2004
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes
2008 StandoutScience
Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro
2012 StandoutNobel
CD8+ Dendritic Cells Use LFA-1 to Capture MHC-Peptide Complexes from Exosomes In Vivo
2007
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor
2012 StandoutNobel
The ESCRT-III Subunit hVps24 Is Required for Degradation but Not Silencing of the Epidermal Growth Factor Receptor
2006
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Biogenesis and Function of Multivesicular Bodies
2007
Focus on Extracellular Vesicles: Introducing the Next Small Big Thing
2016
Microtubule-Dependent Movement of Late Endocytic Vesicles In Vitro: Requirements for Dynein and Kinesin
2004
Exosomes secreted by cortical neurons upon glutamatergic synapse activation specifically interact with neurons
2014
Extracellular vesicles including exosomes are mediators of signal transduction: Are they protective or pathogenic?
2014
Down-regulation of epidermal growth factor receptor signalling within multivesicular bodies
2009
Multivesicular Body Morphogenesis
2011
Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis
2013 StandoutNobel
The early endosome: a busy sorting station for proteins at the crossroads.
2010
Depletion of TSG101 forms a mammalian `Class E' compartment: a multicisternal early endosome with multiple sorting defects
2005
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Plasma membrane deformation by circular arrays of ESCRT-III protein filaments
2008
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
The role of calcium and other ions in sorting and delivery in the late endocytic pathway
2007
THE ESCRT COMPLEXES: Structure and Mechanism of a Membrane-Trafficking Network
2006
The Distribution and Function of Phosphatidylserine in Cellular Membranes
2010
The role of extracellular vesicles in neurodegenerative diseases
2016
Identification and characterization of the nano‐sized vesicles released by muscle cells
2013
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
2008 Standout
Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7–RILP–p150Glued and late endosome positioning
2009
Ca2+Sensitivity of Smooth Muscle and Nonmuscle Myosin II: Modulated by G Proteins, Kinases, and Myosin Phosphatase
2003 Standout
Human tumor nanoparticles induce apoptosis of pancreatic cancer cells
2008
Regulation of Adaptive Immunity by the Innate Immune System
2010 StandoutScience
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Imaging and imagination: understanding the endo-lysosomal system
2008
Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles
2014 Standout
A Localized Wnt Signal Orients Asymmetric Stem Cell Division in Vitro
2013 StandoutScienceNobel
In Vitro Budding of Intralumenal Vesicles into Late Endosomes Is Regulated by Alix and Tsg101
2008
Annexin A8 Regulates Late Endosome Organization and Function
2008
Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes
2008
Disturbed Cholesterol Traffic but Normal Proteolytic Function in LAMP-1/LAMP-2 Double-deficient Fibroblasts
2004
The position of lysosomes within the cell determines their luminal pH
2016
Distinct lipid compositions of two types of human prostasomes
2013
Organizing Polarized Delivery of Exosomes at Synapses
2015
Autophagy in Health and Disease: A Double-Edged Sword
2004 StandoutScience
Works of Julien Fauré being referenced
Role of LBPA and Alix in Multivesicular Liposome Formation and Endosome Organization
2004 StandoutScienceNobel
Exosomes are released by cultured cortical neurones
2006
Topological organization of the cytosolic activating complex of the superoxide-generating NADPH-oxidase. Pinpointing the sites of interaction between p47phox, p67phox and p40phox using the two-hybrid system
1996
Phosphoinositide‐dependent activation of Rho A involves partial opening of the RhoA/Rho‐GDI complex
1999
Interactions between Rho GTPases and Rho GDP dissociation inhibitor (Rho-GDI)
2001
Endosome-to-cytosol transport of viral nucleocapsids
2005
The neuronal endopeptidase ECEL1 is associated with a distinct form of recessive distal arthrogryposis
2012
Late endosome motility depends on lipids via the small GTPase Rab7
2002
Small Angle Neutron Scattering and Gel Filtration Analyses of Neutrophil NADPH Oxidase Cytosolic Factors Highlight the Role of the C-Terminal End of p47phox in the Association with p40phox
2001
PI3P signaling regulates receptor sorting but not transport in the endosomal pathway
2003