Citation Impact
Citing Papers
Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling
2009 StandoutScience
Combined Inhibition of Both p110α and p110β Isoforms of Phosphatidylinositol 3-Kinase Is Required for Sustained Therapeutic Effect in PTEN-Deficient, ER+ Breast Cancer
2016
Alpelisib for PIK3CA -Mutated, Hormone Receptor–Positive Advanced Breast Cancer
2019 Standout
2014
β-Arrestin-mediated Signaling Regulates Protein Synthesis
2008 StandoutNobel
Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma
2015
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
TRB3 Inhibits the Transcriptional Activation of Stress-regulated Genes by a Negative Feedback on the ATF4 Pathway
2007
2016
C/EBP Homology Protein (CHOP) Interacts with Activating Transcription Factor 4 (ATF4) and Negatively Regulates the Stress-dependent Induction of the Asparagine Synthetase Gene
2008
The GCN2‐ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation
2010
mTOR Signaling in Growth Control and Disease
2012 Standout
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Inflammatory links between obesity and metabolic disease
2011 Standout
Transcriptional Repression of ATF4 Gene by CCAAT/Enhancer-binding Protein β (C/EBPβ) Differentially Regulates Integrated Stress Response
2012
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
2007 Standout
Engineering receptors in the secretory pathway for orthogonal signalling control
2022
An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1
2009 Standout
The eIF2α kinases: their structures and functions
2013
Small-Molecule Inhibition of the Interaction between the Translation Initiation Factors eIF4E and eIF4G
2007
New Modes of Translational Control in Development, Behavior, and Disease
2007
Cancer Cell Metabolism: Warburg and Beyond
2008 Standout
Hallmarks of aging: An expanding universe
2023 Standout
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
2012 Standout
Origins and Mechanisms of miRNAs and siRNAs
2009 Standout
The Transcription Factor Network Associated With the Amino Acid Response in Mammalian Cells
2012
Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets
2009 Standout
Translational Control of Long-Lasting Synaptic Plasticity and Memory
2009
Integrating single-cell transcriptomic data across different conditions, technologies, and species
2018 Standout
Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2
2009
FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
2011 Standout
TRB3, a novel ER stress‐inducible gene, is induced via ATF4–CHOP pathway and is involved in cell death
2005
Network organization of the human autophagy system
2010 StandoutNature
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Antiviral effect of the mammalian translation initiation factor 2α kinase GCN2 against RNA viruses
2006
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
Nutrient control of hunger by extrinsic gastrointestinal neurons
2013
Regulation of cancer cell metabolism
2011 Standout
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
mTOR: from growth signal integration to cancer, diabetes and ageing
2010 Standout
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
2009 StandoutNature
Cysteine Depletion, a Key Action to Challenge Cancer Cells to Ferroptotic Cell Death
2020
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
From endoplasmic-reticulum stress to the inflammatory response
2008 StandoutNature
Dephosphorylation of Translation Initiation Factor 2α Enhances Glucose Tolerance and Attenuates Hepatosteatosis in Mice
2008
Connecting the mechanisms of T‐cell regulation: dendritic cells as the missing link
2010
Methods in Mammalian Autophagy Research
2010 Standout
MicroRNA-10a Binds the 5′UTR of Ribosomal Protein mRNAs and Enhances Their Translation
2008
Amino Acid Deprivation Induces the Transcription Rate of the Human Asparagine Synthetase Gene through a Timed Program of Expression and Promoter Binding of Nutrient-responsive Basic Region/Leucine Zipper Transcription Factors as Well as Localized Histone Acetylation
2004
Role of Glutamine Depletion in Directing Tissue-specific Nutrient Stress Responses to L-Asparaginase
2006
Regulation of autophagy by ATF4 in response to severe hypoxia
2010
CDK 4/6 Inhibitors Sensitize PIK3CA Mutant Breast Cancer to PI3K Inhibitors
2014
Modulation of intracellular ROS levels by TIGAR controls autophagy
2009
Neuronal Apoptosis Induced by Endoplasmic Reticulum Stress Is Regulated by ATF4–CHOP-Mediated Induction of the Bcl-2 Homology 3-Only Member PUMA
2010
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
The Inflammasomes
2010 Standout
What We Talk About When We Talk About Fat
2014 Standout
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
2019 StandoutNature
Keeping the eIF2 alpha kinase Gcn2 in check
2014
The PI3K Pathway in Human Disease
2017 Standout
p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling
2008
ATF4-dependent transcription mediates signaling of amino acid limitation
2009
Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP
2010 Standout
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits
2014 Standout
Salermide up‐regulates death receptor 5 expression through the ATF4‐ATF3‐CHOP axis and leads to apoptosis in human cancer cells
2011
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
2012 StandoutNobel
The integrated stress response
2016 Standout
Translational Control and the Unfolded Protein Response
2007
Clues from cell metabolism
2010 StandoutNatureNobel
NAT1/DAP5/p97 and Atypical Translational Control in the Drosophila Circadian Oscillator
2012 StandoutNobel
Role of Glutamine Depletion in Directing Tissue-specific Nutrient Stress Responses to L-Asparaginase
2006
ATF4 is an oxidative stress–inducible, prodeath transcription factor in neurons in vitro and in vivo
2008
Correlative imaging of ionic transport and electronic structure in nano Li0.5FePO4 electrodes
2019 StandoutNobel
CHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis
2013
mTOR and HIF-1α-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome
2009
The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression
2013
Human Fatty Liver Disease: Old Questions and New Insights
2011 StandoutScience
Rapamycin, proliferation and geroconversion to senescence
2018
Increased Susceptibility to DNA Virus Infection in Mice with a GCN2 Mutation
2011 StandoutNobel
Fine‐tuning PERK signaling for neuroprotection
2017
mTOR: a pharmacologic target for autophagy regulation
2015 Standout
Activating Transcription Factor 3 Is Integral to the Eukaryotic Initiation Factor 2 Kinase Stress Response
2004
Signalling to translation: how signal transduction pathways control the protein synthetic machinery
2007
Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor–, granulocyte-macrophage colony-stimulating factor–, and interleukin-3–expressing NOD-SCID IL2Rγnull humanized mice
2011 StandoutNobel
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation
2014 StandoutNobel
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
Coping with stress: eIF2 kinases and translational control
2006
Works of Julien Avérous being referenced
Amino Acid Availability Controls TRB3 Transcription in Liver through the GCN2/eIF2α/ATF4 Pathway
2010
Identification of GCN2 as new redox regulator for oxidative stress prevention in vivo
2011
Molecular mechanisms involved in the adaptation to amino acid limitation in mammals
2010
Regulation of cyclin D1 expression by mTORC1 signaling requires eukaryotic initiation factor 4E-binding protein 1
2007
Induction of CHOP Expression by Amino Acid Limitation Requires Both ATF4 Expression and ATF2 Phosphorylation
2004
When translation meets transformation: the mTOR story
2006
Amino acids as regulators of gene expression: molecular mechanisms
2003
Differences in the Molecular Mechanisms Involved in the Transcriptional Activation of the CHOP and Asparagine Synthetase Genes in Response to Amino Acid Deprivation or Activation of the Unfolded Protein Response
2002
Induction of IGFBP‐1 expression by amino acid deprivation of HepG2 human hepatoma cells involves both a transcriptional activation and an mRNA stabilization due to its 3′UTR
2005
Amino acid deprivation regulates the stress-inducible gene p8 via the GCN2/ATF4 pathway
2011
The GCN2 kinase biases feeding behavior to maintain amino acid homeostasis in omnivores
2005
The amino acid sensor GCN2 biases macronutrient selection during aging
2011