Citation Impact
Citing Papers
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
2003
Genetic Dissection of the Amyloid Precursor Protein in Developmental Function and Amyloid Pathogenesis
2010 StandoutNobel
Alzheimer's disease: synapses gone cold
2011
Intraneuronal Aβ-Amyloid Precedes Development of Amyloid Plaques in Down Syndrome
2001
Oligomerization of Alzheimer's β-Amyloid within Processes and Synapses of Cultured Neurons and Brain
2004
Understanding Synapses: Past, Present, and Future
2008 StandoutNobel
Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer's disease
2010
The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Aβ protofibril formation
2001
Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window
2009
Presenilins are essential for regulating neurotransmitter release
2009 StandoutNatureNobel
Mechanisms and Functional Implications of Adult Neurogenesis
2008 Standout
Proteolytic Processing of Amyloid-β Precursor Protein by Secretases Does Not Require Cell Surface Transport
2004 StandoutNobel
APOE genotype-specific differences in the innate immune response
2007
Intraneuronal amyloid β and reduced brain volume in a novel APP T714I mouse model for Alzheimer's disease
2006
The microbiota in adaptive immune homeostasis and disease
2016 StandoutNature
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Oxidative Damage Is the Earliest Event in Alzheimer Disease
2001 Standout
Extracellular phosphorylation of the amyloid β‐peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease
2011
Cellular Membrane Composition Defines Aβ-Lipid Interactions
2001
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide
2007 Standout
Uncoupled Packaging of Amyloid Precursor Protein and Presenilin 1 into Coat Protein Complex II Vesicles
2004 StandoutNobel
Age‐related changes of intracellular Aβ in cynomolgus monkey brains
2005
Intracellular A-Beta Amyloid, A Sign for Worse Things to Come?
2002
Axon degeneration mechanisms: commonality amid diversity
2005
BACE1 inhibition more effectively suppresses initiation than progression of β-amyloid pathology
2018
Classification and basic pathology of Alzheimer disease
2009
Intraneuronal Aβ accumulation precedes plaque formation in β-amyloid precursor protein and presenilin-1 double-transgenic mice
2001
Aβ localization in abnormal endosomes: association with earliest Aβ elevations in AD and Down syndrome
2004
Autoimmune T cell responses in the central nervous system
2009
Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease
2008
Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides1Published on the World Wide Web on 17 August 1999.1
1999
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
2002 StandoutNature
Intraneuronal Aβ accumulation and origin of plaques in Alzheimer's disease
2005
Positive Association of the Cathepsin D Ala224Val Gene Polymorphism With the Risk of Alzheimer's Disease
2015
Altered Metabolism of the Amyloid β Precursor Protein Is Associated with Mitochondrial Dysfunction in Down's Syndrome
2002
A Dynamic Relationship between Intracellular and Extracellular Pools of Aβ
2006
Uptake and pathogenic effects of amyloid beta peptide 1–42 are enhanced by integrin antagonists and blocked by NMDA receptor antagonists
2002
Presenilin-1 Regulates Intracellular Trafficking and Cell Surface Delivery of β-Amyloid Precursor Protein
2003
Technicolour transgenics: imaging tools for functional genomics in the mouse
2003
Structural and functional features of central nervous system lymphatic vessels
2015 StandoutNature
Alzheimer's disease-like neuropathology of gene-targeted APP-SLxPS1mut mice expressing the amyloid precursor protein at endogenous levels
2005
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Cumulative Effects Associated With Recurrent Concussion in Collegiate Football Players
2003
Post-translational Processing of β-Secretase (β-Amyloid-converting Enzyme) and Its Ectodomain Shedding
2001
A myocardial lineage derives from Tbx18 epicardial cells
2008 StandoutNature
p25/Cyclin-Dependent Kinase 5 Induces Production and Intraneuronal Accumulation of Amyloid βIn Vivo
2006
Amyloid Pathology and Protein Kinase C (PKC): Possible Therapeutics Effects of PKC Activators
2005
Altered mitogen-activated protein kinase signaling, tau hyperphosphorylation and mild spatial learning dysfunction in transgenic rats expressing the β-amyloid peptide intracellularly in hippocampal and cortical neurons
2004
Autophagy in the Pathogenesis of Disease
2008 Standout
Drainage of Cells and Soluble Antigen from the CNS to Regional Lymph Nodes
2013
Intraneuronal amyloid β42 enhanced by heating but counteracted by formic acid
2006
Protein aggregation diseases: pathogenicity and therapeutic perspectives
2010
Rethinking schizophrenia
2010 StandoutNature
Subcellular Topography of Neuronal Aβ Peptide in APPxPS1 Transgenic Mice
2004
The use of formic acid to embellish amyloid plaque detection in Alzheimer's disease tissues misguides key observations
2003
Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles
2003 Standout
Endocytosis Is Required for Synaptic Activity-Dependent Release of Amyloid-β In Vivo
2008
Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation
2006 Standout
Mild Traumatic Brain Injury in U.S. Soldiers Returning from Iraq
2008 Standout
APP Processing and Synaptic Function
2003
Evidence that neurones accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer's disease
2001
Alzheimer's Disease
2010 Standout
Phenotype associated with APP duplication in five families
2006
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Intracellular Aβ and cognitive deficits precede β-amyloid deposition in transgenic arcAβ mice
2006
The Amyloid State of Proteins in Human Diseases
2012 Standout
Furin initiates gelsolin familial amyloidosis in the Golgi through a defect in Ca2+ stabilization
2001
Deep tissue two-photon microscopy
2005 Standout
Localization of presenilin–nicastrin complexes and γ‐secretase activity to the trans‐Golgi network
2003
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Genetics of Alzheimer’s Disease
2014
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
The anatomical and cellular basis of immune surveillance in the central nervous system
2012
Consistent immunohistochemical detection of intracellular β-amyloid42 in pyramidal neurons of Alzheimer's disease entorhinal cortex
2002
Intracellular accumulation of β-amyloid1–42 in neurons is facilitated by the α7 nicotinic acetylcholine receptor in Alzheimer’s disease
2002
Sorting through the Cell Biology of Alzheimer's Disease: Intracellular Pathways to Pathogenesis
2006
Massive CA1/2 Neuronal Loss with Intraneuronal and N-Terminal Truncated Aβ42 Accumulation in a Novel Alzheimer Transgenic Model
2004
β-Amyloid Accumulation Impairs Multivesicular Body Sorting by Inhibiting the Ubiquitin-Proteasome System
2006
Fibroblasts from FAD-linked presenilin 1 mutations display a normal unfolded protein response but overproduce Aβ42 in response to tunicamycin
2004
Intracellular amyloid-β in Alzheimer's disease
2007 Standout
Apolipoprotein E and Low Density Lipoprotein Receptor-related Protein Facilitate Intraneuronal Aβ42 Accumulation in Amyloid Model Mice
2006
Alzheimer's disease-associated amyloid beta interacts with the human serine protease HtrA2/Omi
2004
A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
2017 Standout
LRP in Amyloid‐β Production and Metabolism
2006
Intraneuronal β-Amyloid Expression Downregulates the Akt Survival Pathway and Blunts the Stress Response
2005
Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
2015 Standout
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Intraneuronal Alzheimer Aβ42 Accumulates in Multivesicular Bodies and Is Associated with Synaptic Pathology
2002
Induction of Tau Pathology by Intracerebral Infusion of Amyloid-β-Containing Brain Extract and by Amyloid-β Deposition in APP × Tau Transgenic Mice
2007
Opposing Synaptic Regulation of Amyloid-β Metabolism by NMDA ReceptorsIn Vivo
2011
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
AMPAR Removal Underlies Aβ-Induced Synaptic Depression and Dendritic Spine Loss
2006
Homocysteic acid induces intraneuronal accumulation of neurotoxic Aβ42: Implications for the pathogenesis of Alzheimer's disease
2005
The Arctic Alzheimer mutation facilitates early intraneuronal Aβ aggregation and senile plaque formation in transgenic mice
2005
Oxidative Stress, Accumulation of Biological 'Garbage', and Aging
2006
Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as in Vivo Two-Photon Oxygen Sensors
2015 StandoutNobel
Stimulation of β-Amyloid Precursor Protein Trafficking by Insulin Reduces Intraneuronal β-Amyloid and Requires Mitogen-Activated Protein Kinase Signaling
2001
Intraneuronal Aβ42 accumulation in Down syndrome brain
2002
Inclusion body myositis-like phenotype induced by transgenic overexpression of βAPP in skeletal muscle
2002
Lecanemab in Early Alzheimer’s Disease
2022 Standout
Place cell firing correlates with memory deficits and amyloid plaque burden in Tg2576 Alzheimer mouse model
2008 StandoutNobel
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells
2012
Intraneuronal abeta-amyloid precedes development of amyloid plaques in Down syndrome.
2001
Inclusion-body myositis
2006
Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice
2007
Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells
2003
Use-Dependent Effects of Amyloidogenic Fragments of β-Amyloid Precursor Protein on Synaptic Plasticity in Rat HippocampusIn Vivo
2001
Early intraneuronal Aβ deposition in the hippocampus of APP transgenic mice
2003
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Structure-Based Design of Functional Amyloid Materials
2014 StandoutNobel
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
Axonopathy and Transport Deficits Early in the Pathogenesis of Alzheimer's Disease
2005 Science
Alzheimer's Disease: Genes, Proteins, and Therapy
2001 Standout
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Characterization and adaptive optical correction of aberrations during in vivo imaging in the mouse cortex
2011 StandoutNobel
Intraneuronal amyloid‐β1‐42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death
2004
Alzheimer's Disease Is a Synaptic Failure
2002 StandoutScience
Intraneuronal Aβ Causes the Onset of Early Alzheimer’s Disease-Related Cognitive Deficits in Transgenic Mice
2005
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Designed amyloid fibers as materials for selective carbon dioxide capture
2013 StandoutNobel
Induced CD4+Foxp3+Regulatory T Cells in Immune Tolerance
2012
Two-Photon Absorbing Nanocrystal Sensors for Ratiometric Detection of Oxygen
2009 StandoutNobel
Presenilin 1 Controls γ-Secretase Processing of Amyloid Precursor Protein in Pre-Golgi Compartments of Hippocampal Neurons
1999
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Neuroscience: Breaking Down Scientific Barriers to the Study of Brain and Mind
2000 StandoutScienceNobel
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response
2009 StandoutNobel
The Fluorescent Toolbox for Assessing Protein Location and Function
2006 StandoutScienceNobel
The Evolution of Aβ Peptide Burden in the APP23 Transgenic Mice: Implications for Aβ Deposition in Alzheimer Disease
2001
Selective cytotoxicity of intracellular amyloid β peptide1–42 through p53 and Bax in cultured primary human neurons
2002
The Development of Amyloid β Protein Deposits in the Aged Brain
2006
Mitochondrial Aβ: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease
2005
Cleavage of Amyloid-β Precursor Protein and Amyloid-β Precursor-like Protein by BACE 1
2004 StandoutNobel
The Oligomerization of Amyloid β-Protein Begins Intracellularly in Cells Derived from Human Brain
2000
Works of Julia Tsai being referenced
Fibrillar amyloid deposition leads to local synaptic abnormalities and breakage of neuronal branches
2004
Various Dendritic Abnormalities Are Associated with Fibrillar Amyloid Deposits in Alzheimer's Disease
2007
Rapid labeling of neuronal populations by ballistic delivery of fluorescent dyes
2003
Intraneuronal Aβ42 Accumulation in Human Brain
2000
Lower Cognitive Performance of Older Football Players Possessing Apolipoprotein E ε4
2000
Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer β-amyloid peptides
1999
Swift Entry of Myelin-Specific T Lymphocytes into the Central Nervous System in Spontaneous Autoimmune Encephalomyelitis
2008
Lower Cognitive Performance of Older Football Players Possessing Apolipoprotein E ε4
2000