Citation Impact
Citing Papers
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro
2003 StandoutNobel
Systematic Genetic Analysis with Ordered Arrays of Yeast Deletion Mutants
2001 StandoutScience
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
MSH2–MSH6 stimulates DNA polymerase η, suggesting a role for A:T mutations in antibody genes
2005
Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130
2002 StandoutNobel
Human Mismatch Repair
2005 StandoutNobel
The Full-length Saccharomyces cerevisiae Sgs1 Protein Is a Vigorous DNA Helicase That Preferentially Unwinds Holliday Junctions
2010
Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
2000 StandoutNature
Mapping the DNA Topoisomerase III Binding Domain of the Sgs1 DNA Helicase
2001
RECQ1 Helicase Interacts with Human Mismatch Repair Factors That Regulate Genetic Recombination*[boxs]
2005
The Spring α-Helix Coordinates Multiple Modes of HCV (Hepatitis C Virus) NS3 Helicase Action
2016 StandoutNobel
The DNA-damage response in human biology and disease
2009 StandoutNature
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
2005 StandoutNature
The Bloom's Syndrome Gene Product Interacts with Topoisomerase III
2000
MicroRNAs
2004 Standout
RecQ helicases: multifunctional genome caretakers
2009
Rmi1 stimulates decatenation of double Holliday junctions during dissolution by Sgs1–Top3
2010
The β Sliding Clamp Binds to Multiple Sites within MutL and MutS
2006 StandoutNobel
Cellular roles of DNA topoisomerases: a molecular perspective
2002 Standout
Crystal structure of parallel quadruplexes from human telomeric DNA
2002 StandoutNature
Cell-cycle checkpoints and cancer
2004 StandoutNature
Defending genome integrity during DNA replication: a proposed role for RecQ family helicases
1999
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
Biochemical Characterization of the DNA Helicase Activity of the Escherichia coli RecQ Helicase
2001
Interleukin-11 Signals through the Formation of a Hexameric Receptor Complex
2000
The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases
2001
Interaction of human DNA topoisomerase I with G-quartet structures
2000
The Processing of Holliday Junctions by BLM and WRN Helicases Is Regulated by p53
2002
Human RECQ5β, a protein with DNA helicase and strand‐annealing activities in a single polypeptide
2004
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
2005 StandoutNature
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
2005 StandoutNature
DNA repair pathways as targets for cancer therapy
2008
The Bloom's Syndrome Protein (BLM) Interacts with MLH1 but Is Not Required for DNA Mismatch Repair
2001
The Exonucleolytic and Endonucleolytic Cleavage Activities of Human Exonuclease 1 Are Stimulated by an Interaction with the Carboxyl-terminal Region of the Werner Syndrome Protein
2003
Cloning and expression of an alternatively spliced mRNA encoding a soluble form of the human interleukin‐6 signal transducer gp1301
1997
TRF2 recruits the Werner syndrome (WRN) exonuclease for processing of telomeric DNA
2004
Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1
2001
Chromosomal stability and the DNA double-stranded break connection
2001
Homologous recombinational repair of DNA ensures mammalian chromosome stability
2001
Functional Interaction of p53 and BLM DNA Helicase in Apoptosis
2001
Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom’s syndrome gene
1998
Holliday junction resolution in human cells: two junction endonucleases with distinct substrate specificities
2002
Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS
2000 StandoutNature
The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding
2002
The Involvement of DNA-Damage and -Repair Defects in Neurological Dysfunction
2008
Potential Role for the BLM Helicase in Recombinational Repair via a Conserved Interaction with RAD51
2001
BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination
2003
RecQ helicases and topoisomerases: components of a conserved complex for the regulation of genetic recombination
2001
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
2002 StandoutNature
The Bloom's Syndrome Helicase Interacts Directly with the Human DNA Mismatch Repair Protein hMSH6
2003
Mechanism of homologous recombination: mediators and helicases take on regulatory functions
2006
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Human Bloom Protein Stimulates Flap Endonuclease 1 Activity by Resolving DNA Secondary Structure
2004
Complementary Roles for Exonuclease 1 and Flap Endonuclease 1 in Maintenance of Triplet Repeats
2010
RecQ helicase, in concert with RecA and SSB proteins, initiates and disrupts DNA recombination
1998
Checkpoints: It takes more than time to heal some wounds
2000
The Fanconi Anemia/BRCA pathway: new faces in the crowd
2005
RecQ Helicase and Topoisomerase III Comprise a Novel DNA Strand Passage Function
1999
The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase
2004 StandoutNobel
Analysis of helicase activity and substrate specificity of Drosophila RECQ5
2003
Binding specificity determines polarity of DNA unwinding by the Sgs1 protein of S. cerevisiae
1999
Human Claspin Is a Ring-shaped DNA-binding Protein with High Affinity to Branched DNA Structures
2004 StandoutNobel
Requirement of Non-canonical Activity of Uracil DNA Glycosylase for Class Switch Recombination
2006 StandoutNobel
The Bloom syndrome helicase BLM interacts with TRF2 in ALT cells and promotes telomeric DNA synthesis
2002
DNA double-strand breaks: signaling, repair and the cancer connection
2001 Standout
G4 DNA unwinding by BLM and Sgs1p: substrate specificity and substrate-specific inhibition
2002
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Distinct Activities of Exonuclease 1 and Flap Endonuclease 1 at Telomeric G4 DNA
2010
Checking on the fork: the DNA-replication stress-response pathway
2002
Identification and Characterization of Human MUS81-MMS4 Structure-specific Endonuclease
2003 StandoutNobel
DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells11Edited by J. Karn
2001
Mechanism of Stimulation of Human DNA Ligase I by the Rad9-Rad1-Hus1 Checkpoint Complex
2006 StandoutNobel
Partial suppression of the fission yeast rqh1- phenotype by expression of a bacterial Holliday junction resolvase
2000
BLM–DNA2–RPA–MRN and EXO1–BLM–RPA–MRN constitute two DNA end resection machineries for human DNA break repair
2011 StandoutNobel
Conserved helicase domain of human RecQ4 is required for strand annealing-independent DNA unwinding
2010
Mus81-Eme1 Are Essential Components of a Holliday Junction Resolvase
2001
Processing of G4 DNA by Dna2 Helicase/Nuclease and Replication Protein A (RPA) Provides Insights into the Mechanism of Dna2/RPA Substrate Recognition
2008
Functional overlap between Sgs1–Top3 and the Mms4–Mus81 endonuclease
2001
Human Mus81-Associated Endonuclease Cleaves Holliday Junctions In Vitro
2001
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
Siglec-9, a Novel Sialic Acid Binding Member of the Immunoglobulin Superfamily Expressed Broadly on Human Blood Leukocytes
2000
A phylogenomic study of DNA repair genes, proteins, and processes
1999
Identification of Three Distinct Receptor Binding Sites of Murine Interleukin-11
1999
Phosphorylation of H2AX at Short Telomeres in T Cells and Fibroblasts
2004 StandoutNobel
The NS5A Protein of Hepatitis C Virus Is a Zinc Metalloprotein
2004 StandoutNobel
Branch Migration and Holliday Junction Resolution Catalyzed by Activities from Mammalian Cells
2001
Shelterin: the protein complex that shapes and safeguards human telomeres
2005 Standout
Telomere-binding Protein TRF2 Binds to and Stimulates the Werner and Bloom Syndrome Helicases
2002
Novel pro- and anti-recombination activities of the Bloom’s syndrome helicase
2007
The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase
2001
9 Quelling in Neurospora crassa
2002
An Alternative Form of Replication Protein A Expressed in Normal Human Tissues Supports DNA Repair
2009 StandoutNobel
The Bloom's syndrome helicase suppresses crossing over during homologous recombination
2003 Nature
Telomere instability in a human tumor cell line expressing a dominant-negative WRN protein
2003
The Werner syndrome gene: the molecular basis of RecQ helicase-deficiency diseases
2000
A localized nucleolar DNA damage response facilitates recruitment of the homology-directed repair machinery independent of cell cycle stage
2015
Purification and Characterization of the Sgs1 DNA Helicase Activity of Saccharomyces cerevisiae
1998
The Werner Syndrome Helicase and Exonuclease Cooperate to Resolve Telomeric D Loops in a Manner Regulated by TRF1 and TRF2
2004
RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes
2001 Nature
Cleavage of Model Replication Forks by Fission Yeast Mus81-Eme1 and Budding Yeast Mus81-Mms4
2003
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
DNA Repair Synthesis and Ligation Affect the Processing of Excised Oligonucleotides Generated by Human Nucleotide Excision Repair
2014 StandoutNobel
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
2010 StandoutNobel
Chemical Topology: Complex Molecular Knots, Links, and Entanglements
2011 StandoutNobel
Nuclear structure in normal and Bloom syndrome cells
2000
Telomerase core components protect Candida telomeres from aberrant overhang accumulation
2007 StandoutNobel
Srs2 and Sgs1 DNA Helicases Associate with Mre11 in Different Subcomplexes following Checkpoint Activation and CDK1-Mediated Srs2 Phosphorylation
2005
Telomere length is paternally inherited and is associated with parental lifespan
2007 StandoutNobel
The puzzle of PCNA's many partners
2000
Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors
2001
Inhibition of the Bloom's and Werner's Syndrome Helicases by G-Quadruplex Interacting Ligands
2001
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
2002 StandoutNobel
G-Quadruplex DNA Structures Variations on a Theme
2001
Activation of the signal transducer gp130 by interleukin-11 and interleukin-6 is mediated by similar molecular interactions
1998
The human Bloom syndrome gene suppresses the DNA replication and repair defects of yeastdna2mutants
2003
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination
2009 StandoutNobel
DNA Helicases, Genomic Instability, and Human Genetic Disease
2000
Requirement for Three Novel Protein Complexes in the Absence of the Sgs1 DNA Helicase in Saccharomyces cerevisiae
2001
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
1998 Standout
WRN Helicase and FEN-1 Form a Complex upon Replication Arrest and Together Process Branchmigrating DNA Structures Associated with the Replication Fork
2003
DNA Repair in Drosophila
2000
In Vitro Analysis of the Role of Replication Protein A (RPA) and RPA Phosphorylation in ATR-mediated Checkpoint Signaling
2012 StandoutNobel
Replication protein A: directing traffic at the intersection of replication and repair
2010
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
A human nuclease specific for G4 DNA
2001
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
2008 StandoutNobel
Regulation and Localization of the Bloom Syndrome Protein in Response to DNA Damage
2001
Human DNA Repair Genes
2001 StandoutScienceNobel
The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1
2004 StandoutNobel
Structural Basis of Type II Topoisomerase Inhibition by the Anticancer Drug Etoposide
2011 StandoutScience
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Recombination-mediated lengthening of terminal telomeric repeats requires the Sgs1 DNA helicase
2001
Reconstitution of Human DNA Polymerase δ Using Recombinant Baculoviruses
2002
Works of Julia Karow being referenced
Replication Protein A Physically Interacts with the Bloom's Syndrome Protein and Stimulates Its Helicase Activity
2000
RecQ family helicases: roles in cancer and aging
2000
The Bloom's Syndrome Gene Product Is a 3′-5′ DNA Helicase
1997
Genetic recombination: Helicases and topoisomerases link up
1999
The Bloom's Syndrome Helicase Unwinds G4 DNA
1998
Oligomeric ring structure of the Bloom's syndrome helicase
1999
Werner's syndrome protein (WRN) migrates Holliday junctions and co‐localizes with RPA upon replication arrest
2000
The Bloom's syndrome gene product promotes branch migration of Holliday junctions
2000
Mediation of interleukin-11-dependent biological responses by a soluble form of the interleukin-11 receptor
1996