Citation Impact
Citing Papers
Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
CTLA-4 Control over Foxp3 + Regulatory T Cell Function
2008 StandoutScienceNobel
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
2015 StandoutNobel
Dietary antigens limit mucosal immunity by inducing regulatory T cells in the small intestine
2016 Science
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
Eos Mediates Foxp3-Dependent Gene Silencing in CD4 + Regulatory T Cells
2009 Science
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Genomic definition of multiple ex vivo regulatory T cell subphenotypes
2010
Control of Foxp3 stability through modulation of TET activity
2016
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
The AKT–mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells
2008
Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function
2024
Plasticity of Human Regulatory T Cells in Healthy Subjects and Patients with Type 1 Diabetes
2011
TCR Repertoire and Foxp3 Expression Define Functionally Distinct Subsets of CD4+ Regulatory T Cells
2009
Nonfunctional Regulatory T Cells and Defective Control of Th2 Cytokine Production in Natural Scurfy Mutant Mice
2009
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Transcriptional and epigenetic basis of Treg cell development and function: its genetic anomalies or variations in autoimmune diseases
2020 StandoutNobel
Re-establishing immunological self-tolerance in autoimmune disease
2012 StandoutNobel
Transcription factor Foxp3 and its protein partners form a complex regulatory network
2012
FOXP3 Promoter Demethylation Reveals the Committed Treg Population in Humans
2008
Tregopathies: Monogenic diseases resulting in regulatory T-cell deficiency
2018
Ischemia and reperfusion—from mechanism to translation
2011 Standout
Tbet-positive regulatory T cells accumulate in oropharyngeal cancers with ongoing tumor-specific type 1 T cell responses
2019
Two modes of immune suppression by Foxp3+ regulatory T cells under inflammatory or non-inflammatory conditions
2011 StandoutNobel
Foxp3 Transcription-Factor-Dependent and -Independent Regulation of the Regulatory T Cell Transcriptional Signature
2007
Genetic polymorphism in FOXP3 gene: imbalance in regulatory T-cell role and development of human diseases
2013
Loss of Epigenetic Modification Driven by the Foxp3 Transcription Factor Leads to Regulatory T Cell Insufficiency
2012
Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation
2007
Regulatory T cells exert checks and balances on self tolerance and autoimmunity
2009 StandoutNobel
Regulatory T cell plasticity: beyond the controversies
2011
Treg and CTLA-4: Two intertwining pathways to immune tolerance
2013
Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo
2009
Function of a Foxp3 cis -Element in Protecting Regulatory T Cell Identity
2014
Retinoic Acid Enhances Foxp3 Induction Indirectly by Relieving Inhibition from CD4+CD44hi Cells
2008
The development and function of regulatory T cells
2009
A Requisite Role for Induced Regulatory T Cells in Tolerance Based on Expanding Antigen Receptor Diversity
2011
Inflammation-induced repression of chromatin bound by the transcription factor Foxp3 in regulatory T cells
2014
Treg Cells, Life History, and Diversity
2012
Continuous requirement for the TCR in regulatory T cell function
2014
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Regulatory T Cells in Allergy and Asthma
2017
Development of Foxp3+ Regulatory T Cells Is Driven by the c-Rel Enhanceosome
2009
Linked T Cell Receptor and Cytokine Signaling Govern the Development of the Regulatory T Cell Repertoire
2008
Novel Foxo1-dependent transcriptional programs control Treg cell function
2012 Nature
DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3+ conventional T cells
2007
Phenotypical and functional specialization of FOXP3+ regulatory T cells
2011
Plasticity of CD4+ FoxP3+ T cells
2009
Regulatory T Cells: History and Perspective
2011 StandoutNobel
T-bet+ Treg Cells Undergo Abortive Th1 Cell Differentiation due to Impaired Expression of IL-12 Receptor β2
2012
Systems biology of innate immunity
2008
Self-antigen-Driven Activation Induces Instability of Regulatory T Cells during an Inflammatory Autoimmune Response
2013
Regulatory T cells in autoimmune disease
2018
Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells
2011
Induced Regulatory T Cells: Their Development, Stability, and Applications
2016
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
2010 Nature
The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
2009
FOXP3 and scurfy: how it all began
2014 StandoutNobel
Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor
2009 StandoutNobel
The regulation of immune tolerance by FOXP3
2017
Decrease of Foxp3+ Treg Cell Number and Acquisition of Effector Cell Phenotype during Lethal Infection
2009
Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces
2008
Regulatory T cells: stability revisited
2011
The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells
2011
A Genome-wide CRISPR Screen Reveals a Role for the Non-canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function
2020
The Chromatin-Modifying Enzyme Ezh2 Is Critical for the Maintenance of Regulatory T Cell Identity after Activation
2015
PD-1 marks dysfunctional regulatory T cells in malignant gliomas
2016
T Cell Receptor Stimulation-Induced Epigenetic Changes and Foxp3 Expression Are Independent and Complementary Events Required for Treg Cell Development
2012 StandoutNobel
Regulatory T cells: how do they suppress immune responses?
2009 StandoutNobel
High prevalence of Streptococcus pyogenes Cas9-reactive T cells within the adult human population
2018
Prevention of Allograft Rejection by Use of Regulatory T Cells With an MHC-Specific Chimeric Antigen Receptor
2016
Proteomic Analyses of Human Regulatory T Cells Reveal Adaptations in Signaling Pathways that Protect Cellular Identity
2018
Regulatory T cells in cancer immunotherapy
2016 StandoutNobel
Regulatory T Cells: Molecular and Cellular Basis for Immunoregulation
2017
Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment
2016 StandoutNobel
Lineage-specific DNA methylation in T cells correlates with histone methylation and enhancer activity
2009
Next-generation insights into regulatory T cells: expression profiling and FoxP3 occupancy in Human
2011
Global Mapping of H3K4me3 and H3K27me3 Reveals Specificity and Plasticity in Lineage Fate Determination of Differentiating CD4+ T Cells
2009
Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells
2017
Past, Present, and Future of Regulatory T Cell Therapy in Transplantation and Autoimmunity
2019
Control of the Inheritance of Regulatory T Cell Identity by a cis Element in the Foxp3 Locus
2014
Induction of T cell anergy: integration of environmental cues and infectious tolerance
2010
Transcription factor Foxp1 regulates Foxp3 chromatin binding and coordinates regulatory T cell function
2019
Distinct Foxp3 enhancer elements coordinate development, maintenance, and function of regulatory T cells
2021 StandoutNobel
Th17 and Regulatory T Cells in Mediating and Restraining Inflammation
2010
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses
2009 Nature
The plasticity and stability of regulatory T cells
2013 StandoutNobel
Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions
2009
Peripherally Induced Tregs – Role in Immune Homeostasis and Autoimmunity
2013
Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
2024 StandoutNobel
Runx-CBFβ complexes control expression of the transcription factor Foxp3 in regulatory T cells
2009
Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells
2012
Stability of Regulatory T-cell Lineage
2011
Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues
2017
Regulatory T cells – a brief history and perspective
2007 StandoutNobel
Regulatory T Cell-Specific Epigenomic Region Variants Are a Key Determinant of Susceptibility to Common Autoimmune Diseases
2020 StandoutNobel
A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells
2012
Regulatory T cells in allergic diseases
2016
Development and Maintenance of Regulatory T cells
2013 StandoutNobel
Inflammation-Driven Reprogramming of CD4+Foxp3+ Regulatory T Cells into Pathogenic Th1/Th17 T Effectors Is Abrogated by mTOR Inhibition in vivo
2012
CD45RA Distinguishes CD4+CD25+CD127−/low TSDR Demethylated Regulatory T Cell Subpopulations With Differential Stability and Susceptibility to Tacrolimus-Mediated Inhibition of Suppression
2016
Nuclear Factor-κB Modulates Regulatory T Cell Development by Directly Regulating Expression of Foxp3 Transcription Factor
2009
Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer
2019 StandoutNobel
The Role of Retinoic Acid in Tolerance and Immunity
2011
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Regulatory T Cells: Mechanisms of Differentiation and Function
2007 Standout
Genetic and epigenetic basis of Treg cell development and function: from a FoxP3‐centered view to an epigenome‐defined view of natural Treg cells
2014 StandoutNobel
CD147 (Basigin/Emmprin) identifies FoxP3+CD45RO+CTLA4+-activated human regulatory T cells
2011
Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3 high regulatory T cells in humans
2015 StandoutNobel
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Regulatory T Cells and Human Disease
2020 StandoutNobel
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
Heterogeneity of natural Foxp3 + T cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity
2009
c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells
2009
Using histone deacetylase inhibitors to enhance Foxp3+ regulatory T‐cell function and induce allograft tolerance
2009
From IPEX syndrome to FOXP3 mutation: a lesson on immune dysregulation
2016
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells
2012
The Percentage of FoxP3+Helios+ Treg Cells Correlates Positively With Disease Activity in Systemic Lupus Erythematosus
2013
SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-γ and IL-17A production
2011
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
The enhancer and promoter landscape of human regulatory and conventional T-cell subpopulations
2014
Lineage stability and phenotypic plasticity of Foxp3+ regulatory T cells
2014
Treg functional stability and its responsiveness to the microenvironment
2014
Single-Cell Analysis of the Human T Regulatory Population Uncovers Functional Heterogeneity and Instability within FOXP3+ Cells
2011
CD161 defines the subset of FoxP3+ T cells capable of producing proinflammatory cytokines
2013
New Insights into the Molecular Basis of T Cell Anergy: Anergy Factors, Avoidance Sensors, and Epigenetic Imprinting
2009
Molecular control of regulatory T cell development and function
2017 StandoutNobel
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Massive ex Vivo Expansion of Human Natural Regulatory T Cells (T regs ) with Minimal Loss of in Vivo Functional Activity
2011
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
Helios+ and Helios− Cells Coexist within the Natural FOXP3+ T Regulatory Cell Subset in Humans
2013
Emerging Challenges in Regulatory T Cell Function and Biology
2007 StandoutScienceNobel
T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR
2008
Prevention of type 1 diabetes in mice by tolerogenic vaccination with a strong agonist insulin mimetope
2011
The Ets-1 transcription factor controls the development and function of natural regulatory T cells
2010
Conditional stability of T cells
2010 StandoutNatureNobel
Functionally distinct subsets of human FOXP3+ Treg cells that phenotypically mirror effector Th cells
2012
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Neuropilin-1 distinguishes natural and inducible regulatory T cells among regulatory T cell subsets in vivo
2012
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Induced CD4+Foxp3+Regulatory T Cells in Immune Tolerance
2012
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
Regulatory and T Effector Cells Have Overlapping Low to High Ranges in TCR Affinities for Self during Demyelinating Disease
2015
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
Single dose of anti–CTLA-4 enhances CD8 + T-cell memory formation, function, and maintenance
2010 StandoutNobel
CD4+FOXP3+ T Regulatory Cells in Human Autoimmunity: More Than a Numbers Game
2011
Helper T‐cell identity and evolution of differential transcriptomes and epigenomes
2013
Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice
2011 StandoutNobel
Enhancement of antigen-specific Treg vaccination in vivo
2010
Regulatory T Cell Development
2020
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
Differentiation of Effector CD4 T Cell Populations
2010 Standout
Histone Deacetylases 6 and 9 and Sirtuin-1 Control Foxp3 + Regulatory T Cell Function Through Shared and Isoform-Specific Mechanisms
2012
tTregs, pTregs, and iTregs: similarities and differences
2014
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody
2018 StandoutNobel
Coexpression of TIGIT and FCRL3 Identifies Helios+ Human Memory Regulatory T Cells
2015
Works of Julia K. Polansky being referenced
Peripherally Induced Treg: Mode, Stability, and Role in Specific Tolerance
2008
Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage?
2008
Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells
2010
Foxp3 occupancy and regulation of key target genes during T-cell stimulation
2007 Nature
DNA methylation controls Foxp3 gene expression
2008
Epigenetic Control of the foxp3 Locus in Regulatory T Cells
2007
Active Demethylation of the Foxp3 Locus Leads to the Generation of Stable Regulatory T Cells within the Thymus
2013