Citation Impact
Citing Papers
Circadian oscillation of nucleotide excision repair in mammalian brain
2009 StandoutNobel
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
The DNA-damage response in human biology and disease
2009 StandoutNature
Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse
1994 StandoutNobel
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
1991 Standout
The Influence of Chromosomal Location on the Expression of Two Transgenes in Mice
1999 StandoutNobel
Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase
2005 StandoutNature
Targeted Disruption of the β2 Adrenergic Receptor Gene
1999 StandoutNobel
The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases
1993 StandoutNature
Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
1993 Standout
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
1992 Standout
Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor gene in mice
1995 StandoutNatureNobel
Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks
2009 StandoutNobel
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
2005 StandoutNature
MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes
1998 Standout
The Breast Cancer Susceptibility Gene BRCA1 Is Required for Subnuclear Assembly of Rad51 and Survival following Treatment with the DNA Cross-linking Agent Cisplatin
2000
Production of a severe cystic fibrosis mutation in mice by gene targeting
1993 StandoutNobel
Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein
1997 StandoutNature
Disruption of the cystic fibrosis transmembrane conductance regulator gene in embryonic stem cells by gene targeting
1992 StandoutNobel
Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm
2000 StandoutNobel
Comprehensive computational design of mCreI homing endonuclease cleavage specificity for genome engineering
2011 StandoutNobel
Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
1993 Standout
Successful targeting of the mouse cystic fibrosis transmembrane conductance regulator gene in embryonal stem cells
1992
Modifying the mammalian genome by gene targeting
1991
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
1999 StandoutNature
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
1995 Standout
DNA double-strand breaks associated with replication forks are predominantly repaired by homologous recombination involving an exchange mechanism in mammalian cells11Edited by J. Karn
2001
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
1992 StandoutNature
Mesodermally expressed Drosophila microRNA-1 is regulated by Twist and is required in muscles during larval growth
2005 StandoutNobel
Choose your target
2000 StandoutNobel
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer
2012 Standout
Targeted homologous recombination in mammalian cells
1992
Repair of DNA interstrand cross-links
2001
Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers
2009 Standout
Disruption of c-mos causes parthenogenetic development of unfertilized mouse eggs
1994 StandoutNatureNobel
Essential functions of synapsins I and II in synaptic vesicle regulation
1995 StandoutNatureNobel
The role of Rab3A in neurotransmitter release
1994 StandoutNatureNobel
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
An Animal Model for Cystic Fibrosis Made by Gene Targeting
1992 StandoutScienceNobel
Deficiency of human BRCA2 leads to impaired homologous recombination but maintains normal nonhomologous end joining
2001
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Cotransformation and Gene Targeting in Mouse Embryonic Stem Cells
1991 StandoutNobel
Consecutive inactivation of both alleles of the pim-1 proto-oncogene by homologous recombination in embryonic stem cells
1990 Nature
Bone Resorption by Osteoclasts
2000 StandoutScience
Proliferation of multipotent hematopoietic cells controlled by a truncated erythropoietin receptor transgene.
1996 StandoutNobel
Identification of Genes Involved in Repair of DNA Double-Strand Breaks in Mammalian Cells
1998
Impaired Long-Term Potentiation, Spatial Learning, and Hippocampal Development in fyn Mutant Mice
1992 StandoutScienceNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Rescuing impairment of long-term potentiation in fyn-deficient mice by introducing Fyn transgene
1997 StandoutNobel
Reprogramming homing endonuclease specificity through computational design and directed evolution
2013 StandoutNobel
XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
1999
Rabphilin Knock-Out Mice Reveal That Rabphilin Is Not Required for Rab3 Function in Regulating Neurotransmitter Release
1999 StandoutNobel
Targeted disruption of the mouse beta1-adrenergic receptor gene: developmental and cardiovascular effects.
1996 StandoutNobel
Gene correction in hematopoietic progenitor cells by homologous recombination
2000 StandoutNobel
Host Cell DNA Repair Pathways in Adeno-Associated Viral Genome Processing
2006
Fabry Disease, an Under-Recognized Multisystemic Disorder: Expert Recommendations for Diagnosis, Management, and Enzyme Replacement Therapy
2003
Correction of a human beta S-globin gene by gene targeting.
1991 StandoutNobel
Cotransformation and gene targeting in mouse embryonic stem cells.
1991 StandoutNobel
Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs.
1992
The Molecular Biology of Memory Storage: A Dialogue Between Genes and Synapses
2001 StandoutScienceNobel
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
Brca1 Controls Homology-Directed DNA Repair
1999
Gene Targeting by Homologous Recombination in Drosophila
2000 Science
Altering mice by homologous recombination using embryonic stem cells.
1994 StandoutNobel
Works of Julia B. Scheerer being referenced
Targeted gene replacement at the endogenousAPRT locus in CHO cells
1990
Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene.
1995
Homology dependence of targeted recombination at the Chinese hamster APRT locus.
1994
Targeted homologous recombination at the endogenous adenine phosphoribosyltransferase locus in Chinese hamster cells.
1989
Differential assay for lysosomal alpha-galactosidases in human tissues and its application to Fabry's disease
1981