Citation Impact
Citing Papers
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
2020 StandoutScience
Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy participants
2021 Standout
Single particle electron cryo-microscopy of a mammalian ion channel
2014 StandoutNobel
The mechanism of sodium and substrate release from the binding pocket of vSGLT
2010 Nature
Investigation of Mendelian forms of obesity holds out the prospect of personalized medicine
2010
An artificial molecular pump
2015 StandoutNobel
The Two Na+ Sites in the Human Serotonin Transporter Play Distinct Roles in the Ion Coupling and Electrogenicity of Transport
2013
Clinical practice guidelines for the perioperative nutritional, metabolic, and nonsurgical support of the bariatric surgery patient—2013 update: Cosponsored by american association of clinical endocrinologists, The obesity society, and american society for metabolic & bariatric surgery*
2013 Standout
REVIEW ON CPP: Measuring reward with the conditioned place preference (CPP) paradigm: update of the last decade
2007 Standout
Molecular Dynamics Simulation for All
2018 Standout
Simple screening method for improving membrane protein thermostability
2011
mTOR at the nexus of nutrition, growth, ageing and disease
2020 Standout
Mutational Mapping and Modeling of the Binding Site for (S)-Citalopram in the Human Serotonin Transporter
2009
The Mechanistic Basis for Noncompetitive Ibogaine Inhibition of Serotonin and Dopamine Transporters
2012
mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient
2017
Parkinson's disease
2015 Standout
Understanding the pathophysiology of depression: From monoamines to the neurogenesis hypothesis model - are we there yet?
2017
X-ray structures and mechanism of the human serotonin transporter
2016 Nature
Synthesis of 3,7‐Disubstituted Imipramines by Palladium‐Catalysed Amination/Cyclisation and Evaluation of Their Inhibition of Monoamine Transporters
2011
Structures of membrane proteins
2010 StandoutNobel
Diverse Engineered Heme Proteins Enable Stereodivergent Cyclopropanation of Unactivated Alkenes
2018 StandoutNobel
X-ray structure of dopamine transporter elucidates antidepressant mechanism
2013 Nature
Small molecule drug screening in Drosophila identifies the 5HT2A receptor as a feeding modulation target
2013 Standout
The Significance of Chirality in Drug Design and Development
2011
Unlocking the molecular secrets of sodium-coupled transporters
2009 Nature
Indoles as therapeutics of interest in medicinal chemistry: Bird's eye view
2017 Standout
The Mechanism of a Neurotransmitter:Sodium Symporter—Inward Release of Na+ and Substrate Is Triggered by Substrate in a Second Binding Site
2008
Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila
2008
Human Disease Models in Drosophila melanogaster and the Role of the Fly in Therapeutic Drug Discovery
2011
Place Conditioning and Locomotor Effects of N-Substituted, 4′,4′′-Difluorobenztropine Analogs in Rats
2005
Chemical constituents of Panax ginseng and Panax notoginseng explain why they differ in therapeutic efficacy
2020 Standout
Ginsenoside Rg1 protects against ischemic/reperfusion-induced neuronal injury through miR-144/Nrf2/ARE pathway
2018
A review of new developments in the Friedel–Crafts alkylation – From green chemistry to asymmetric catalysis
2010 Standout
Neuroprotective effect of ginsenoside Rg1 prevents cognitive impairment induced by isoflurane anesthesia in aged rats via antioxidant, anti-inflammatory and anti-apoptotic effects mediated by the PI3K/AKT/GSK-3β pathway
2016
Therapeutic Potential of Ginsenosides as an Adjuvant Treatment for Diabetes
2018
A Membrane Burial Potential with H-Bonds and Applications to Curved Membranes and Fast Simulations
2018 StandoutNobel
Iron Catalysis in Organic Synthesis
2015 Standout
Design and Synthesis of Nonequilibrium Systems
2015 StandoutNobel
Contribution of Organofluorine Compounds to Pharmaceuticals
2020 Standout
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Inhibition of TNF-α–mediated NF-κB Activation by Ginsenoside Rg1 Contributes the Attenuation of Cardiac Hypertrophy Induced by Abdominal Aorta Coarctation
2016
Visualizing Functional Motions of Membrane Transporters with Molecular Dynamics Simulations
2013
Catalytic Asymmetric Hydroalkoxylation of C–C Multiple Bonds
2021 StandoutNobel
The Concise Guide to PHARMACOLOGY 2013/14: G Protein‐Coupled Receptors
2013
Common Folds and Transport Mechanisms of Secondary Active Transporters
2013
Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation
2009
Superbase-Catalyzed anti-Markovnikov Alcohol Addition Reactions to Aryl Alkenes
2018
Synthesis and Biological Evaluation of Bupropion Analogues as Potential Pharmacotherapies for Smoking Cessation
2010
Assessing Atropisomer Axial Chirality in Drug Discovery and Development
2011 Standout
Highly efficient synthesis of functionalized dihydronaphthalenes, tetrahydronaphthalenes, and tetrahydroisoquinolines by iron-catalyzed intramolecular Friedel–Crafts reaction of aryl-containing propargylic alcohols
2009
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Microglial M1/M2 polarization and metabolic states
2015 Standout
Visible‐Light Photocatalysis: Does It Make a Difference in Organic Synthesis?
2018 Standout
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Structure−Activity Relationships for a Novel Series of Citalopram (1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile) Analogues at Monoamine Transporters
2010
The Sac1 Domain of SYNJ 1 Identified Mutated in a Family with Early‐Onset Progressive P arkinsonism with Generalized Seizures
2013
Age-Related Reduction of Recovery Sleep and Arousal Threshold inDrosophila
2016 StandoutNobel
Synthesis and Biological Evaluation of Bupropion Analogues as Potential Pharmacotherapies for Cocaine Addiction
2009
Works of Juan Zhen being referenced
LeuT-Desipramine Structure Reveals How Antidepressants Block Neurotransmitter Reuptake
2007 Science
Concentration of receptor and ligand revisited in a modified receptor binding protocol for high-affinity radioligands: [3H]Spiperone binding to D2 and D3 dopamine receptors
2010
Substrate and drug binding sites in LeuT
2010
Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine
2004
Homozygous loss-of-function mutations in the gene encoding the dopamine transporter are associated with infantile parkinsonism-dystonia
2009
Antidepressant specificity of serotonin transporter suggested by three LeuT–SSRI structures
2009
Ginsenoside Rg1 ameliorates oxidative stress and myocardial apoptosis in streptozotocin-induced diabetic rats
2015
Further structural optimization of cis-(6-benzhydryl-piperidin-3-yl)-benzylamine and 1,4-diazabicyclo[3.3.1]nonane derivatives by introducing an exocyclic hydroxyl group: Interaction with dopamine, serotonin, and norepinephrine transporters
2008
Synthesis and Biological Characterization of (3R,4R)‐4‐(2‐(Benzhydryloxy)ethyl)‐1‐((R)‐2‐hydroxy‐2‐phenylethyl)‐piperidin‐3‐ol and Its Stereoisomers for Activity toward Monoamine Transporters
2009
The Importance of Company: Na+ and Cl− Influence Substrate Interaction with SLC6 Transporters and Other Proteins
2006
Further Structure–Activity Relationships Study of Hybrid 7-{[2-(4-Phenylpiperazin-1-yl)ethyl]propylamino}-5,6,7,8-tetrahydronaphthalen-2-ol Analogues: Identification of a High-Affinity D3-Preferring Agonist with Potent in Vivo Activity with Long Duration of Action
2007
Ginsenoside Rg1 ameliorates diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress‐induced apoptosis in a streptozotocin‐induced diabetes rat model
2016