Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
Insights into Translational Termination from the Structure of RF2 Bound to the Ribosome
2008 StandoutScienceNobel
Structural analysis of intrinsically disordered proteins by small-angle X-ray scattering
2011
Stereochemistry of Glutamate Receptor Agonist Efficacy: Engineering a Dual-Specificity AMPA/Kainate Receptor
2004
(S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic Acid, a Potent and Selective Agonist at the GluR5 Subtype of Ionotropic Glutamate Receptors. Synthesis, Modeling, and Molecular Pharmacology
2003
Subtype selective kainic acid receptor agonists: Discovery and approaches to rational design
2008
Subtype selectivity and flexibility of ionotropic glutamate receptors upon antagonist ligand binding
2006
Kainate receptors: Pharmacology, function and therapeutic potential
2008
Divergent Pharmacological Activity of Novel Marine-Derived Excitatory Amino Acids on Glutamate Receptors
2005
3-Substituted phenylalanines as selective AMPA- and kainate receptor ligands
2009
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Block of Kainate Receptor Desensitization Uncovers a Key Trafficking Checkpoint
2006
Concanavalin‐A reports agonist‐induced conformational changes in the intact GluR6 kainate receptor
2006
Engineering a high-affinity allosteric binding site for divalent cations in kainate receptors
2008
Energetics of glutamate receptor ligand binding domain dimer assembly are modulated by allosteric ions
2009
Molecular Basis of Kainate Receptor Modulation by Sodium
2008
Crystal Structures of the Kainate Receptor GluR5 Ligand Binding Core Dimer with Novel GluR5-Selective Antagonists
2006
Novel Analogs and Stereoisomers of the Marine Toxin Neodysiherbaine with Specificity for Kainate Receptors
2007
The Structural Basis for mRNA Recognition and Cleavage by the Ribosome-Dependent Endonuclease RelE
2009 StandoutNobel
Structural mechanism of glutamate receptor activation and desensitization
2014 Nature
Synthesis and Pharmacology of Willardiine Derivatives Acting as Antagonists of Kainate Receptors
2005
Mutations to the Kainate Receptor Subunit GluR6 Binding Pocket That Selectively Affect Domoate Binding
2008
Selective agonist binding of (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) and 2S-(2α,3β,4β)-2-carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid (kainate) receptors: a molecular modeling study
2003
Glutamate receptor ion channels
2005 Standout
Rescue of abnormal phenotypes in δ2 glutamate receptor‐deficient mice by the extracellular N‐terminal and intracellular C‐terminal domains of the δ2 glutamate receptor
2009
Glutamate Receptor Ion Channels: Structure, Regulation, and Function
2010 Standout
Single-Molecule Discrimination of Discrete Perisynaptic and Distributed Sites of Actin Filament Assembly within Dendritic Spines
2010 StandoutNobel
Glutamate receptors at atomic resolution
2006 Nature
Minimal Sulfated Carbohydrates for Recognition by L-selectin and the MECA-79 Antibody
2000 StandoutNobel
Conformational Changes in the Ligand-binding Domain of a Functional Ionotropic Glutamate Receptor
2005
Solution X-ray Scattering Evidence for Agonist- and Antagonist-induced Modulation of Cleft Closure in a Glutamate Receptor Ligand-binding Domain
2005
Structural aspects of AMPA receptor activation, desensitization and deactivation
2007
3-Hydroxypyridazine 1-oxides as carboxylate bioisosteres: A new series of subtype-selective AMPA receptor agonists
2006
Time‐dependent insulin oligomer reaction pathway prior to fibril formation: Cooling and seeding
2009 StandoutNobel
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Protein design with fragment databases
2011
Interactions of the Release Factor RF1 with the Ribosome as Revealed by Cryo-EM
2006 StandoutNobel
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
Dissecting polysialic acid and NCAM functions in brain development
2007
Regulation of AMPA Receptor Gating by Ligand Binding Core Dimers
2004
Structural Basis for the Substrate Specificity of Tobacco Etch Virus Protease
2002
AMPA Receptor Trafficking at Excitatory Synapses
2003
Characterization of a Soluble Ligand Binding Domain of the NMDA Receptor Regulatory Subunit NR3A
2006
Structural aspects of translation termination on the ribosome
2011
Tweaking Agonist Efficacy at N-Methyl-d-aspartate Receptors by Site-Directed Mutagenesis
2005
Atomistic mechanism for the activation and desensitization of an AMPA-subtype glutamate receptor
2011
Pharmacological characterization of (4R)-alkyl glutamate analogues at the ionotropic glutamate receptors — Focus on subtypes iGlu5–7
2009
Cancer-associated 2-oxoglutarate analogues modify histone methylation by inhibiting histone lysine demethylases
2018
Immunoglobulin superfamily cell adhesion molecules: zippers and signals
2007
Structural Features of the Glutamate Binding Site in Recombinant NR1/NR2A N-Methyl-D-aspartate Receptors Determined by Site-Directed Mutagenesis and Molecular Modeling
2005
Biological Activity and Biotechnological Aspects of Peptide Nucleic Acid
2006
A Model for How Ribosomal Release Factors Induce Peptidyl-tRNA Cleavage in Termination of Protein Synthesis
2007
Molecular mechanism of ligand recognition by NR3 subtype glutamate receptors
2008
What recent ribosome structures have revealed about the mechanism of translation
2009 StandoutNatureNobel
T-cell immunity of SARS-CoV: Implications for vaccine development against MERS-CoV
2016
Adhesion molecule signalling: not always a sticky business
2011
Iterative In Situ Click Chemistry Creates Antibody‐like Protein‐Capture Agents
2009 StandoutNobel
The Geometry of the Ribosomal Polypeptide Exit Tunnel
2006 StandoutNobel
Conformational restriction blocks glutamate receptor desensitization
2006
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Structure of the mammalian ribosomal pre-termination complex associated with eRF1•eRF3•GDPNP
2013 StandoutNobel
Release Factors 2 from Escherichia coli and Thermus thermophilus: structural, spectroscopic and microcalorimetric studies
2007
Competitive AMPA receptor antagonists
2006
A Broad-Spectrum Inhibitor of CRISPR-Cas9
2017 StandoutNobel
New developments in theATSASprogram package for small-angle scattering data analysis
2012 Standout
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
2020 Standout
From natural to designer self-assembling biopolymers, the structural characterisation of fibrous proteins & peptides using fibre diffraction
2010
Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors
2005
Molecular Basis for Bacterial Class I Release Factor Methylation by PrmC
2005
Morphological Characterization of Molecular Complexes Present in the Synaptic Cleft
2005
The termination of translation
2008 StandoutNobel
A Domain Linking the AMPA Receptor Agonist Binding Site to the Ion Pore Controls Gating and CauseslurcherProperties when Mutated
2007
RF3 Induces Ribosomal Conformational Changes Responsible for Dissociation of Class I Release Factors
2007 StandoutNobel
Role of the Ion Channel Extracellular Collar in AMPA Receptor Gating
2017
Structural biology of NCAM homophilic binding and activation of FGFR
2005
Dynamics of the base of ribosomal A-site finger revealed by molecular dynamics simulations and Cryo-EM
2009 StandoutNobel
Inflammatory caspases are innate immune receptors for intracellular LPS
2014 StandoutNature
Structure and Dynamics of AMPA Receptor GluA2 in Resting, Pre-Open, and Desensitized States
2014
Control of NMDA Receptor Function by the NR2 Subunit Amino-Terminal Domain
2009
The Free Energy Landscapes Governing Conformational Changes in a Glutamate Receptor Ligand-Binding Domain
2007
Structural and Single-Channel Results Indicate That the Rates of Ligand Binding Domain Closing and Opening Directly Impact AMPA Receptor Gating
2008
The Extracellular Architecture of Adherens Junctions Revealed by Crystal Structures of Type I Cadherins
2011 StandoutNobel
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
Kainate receptors
2006
Zinc inhibition of rat NR1/NR2AN‐methyl‐d ‐aspartate receptors
2007
Characterisation of UBP296: a novel, potent and selective kainate receptor antagonist
2004
Molecular Dynamics Simulations of the Ligand-binding Domain of an N-Methyl-d-aspartate Receptor
2006
Structural basis for partial agonist action at ionotropic glutamate receptors
2003
Impedance sensing of allergen–antibody interaction on glassy carbon electrode modified by gold electrodeposition
2006
Exploring the repeat protein universe through computational protein design
2015 StandoutNatureNobel
Controlling protein assembly on inorganic crystals through designed protein interfaces
2019 StandoutNatureNobel
Glutamate Receptor Gating
2004
The Relationship between Agonist Potency and AMPA Receptor Kinetics
2006
Two Distinct Components of Release Factor Function Uncovered by Nucleophile Partitioning Analysis
2007
LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength
2016 StandoutNobel
Distinct Structural Pathways Coordinate the Activation of AMPA Receptor-Auxiliary Subunit Complexes
2016
Amyloid fibrils
2008
Structural basis for translation termination on the 70S ribosome
2008 Nature
A Peptoid “Antibody Surrogate” That Antagonizes VEGF Receptor 2 Activity
2008
Chemo-Enzymatic Synthesis of a Series of 2,4-Syn-Functionalized (S)-Glutamate Analogues: New Insight into the Structure−Activity Relation of Ionotropic Glutamate Receptor Subtypes 5, 6, and 7
2008
Ligand-Gated Ion Channels: New Insights into Neurological Disorders and Ligand Recognition
2012
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Improving Protein Expression, Stability, and Function with ProteinMPNN
2024 StandoutNobel
Structural Insight into Nascent Polypeptide Chain–Mediated Translational Stalling
2009 StandoutScienceNobel
Coupling of Prolyl Peptide Bond Isomerization and Ca2+Binding in a C-type Mannose-Binding Protein
1998
The multifaceted subunit interfaces of ionotropic glutamate receptors
2014
Synthesis and Pharmacological Characterization of N3-Substituted Willardiine Derivatives: Role of the Substituent at the 5-Position of the Uracil Ring in the Development of Highly Potent and Selective GLUK5 Kainate Receptor Antagonists
2007
Unconventional Mechanisms of Protein Transport to the Cell Surface of Eukaryotic Cells
2008
Engineered Biosynthesis of β‐Alkyl Tryptophan Analogues
2018 StandoutNobel
Seven Post-synthetic Covalent Reactions in Tandem Leading to Enzyme-like Complexity within Metal–Organic Framework Crystals
2016 StandoutNobel
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
Ca2+-Dependent Structural Changes in C-type Mannose-Binding Proteins,
1998
Molecular basis for insulin fibril assembly
2009
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Peptide Release on the Ribosome: Mechanism and Implications for Translational Control
2008
Architecture of fully occupied GluA2 AMPA receptor–TARP complex elucidated by cryo-EM
2016 Nature
Crystal structure of soluble MD-1 and its interaction with lipid IVa
2010
The N-Terminal Domain of GluD2 (GluRδ2) Recruits Presynaptic Terminals and Regulates Synaptogenesis in the CerebellumIn Vivo
2009
The mammalian central nervous synaptic cleft contains a high density of periodically organized complexes
2005 StandoutNobel
Gold Nanoparticles in Chemical and Biological Sensing
2012 Standout
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
Probing the Function, Conformational Plasticity, and Dimer−Dimer Contacts of the GluR2 Ligand-Binding Core: Studies of 5-Substituted Willardiines and GluR2 S1S2 in the Crystal,
2003
Functional Characterization of Tet-AMPA [Tetrazolyl-2-amino-3-(3-hydroxy-5-methyl- 4-isoxazolyl)propionic Acid] Analogues at Ionotropic Glutamate Receptors GluR1−GluR4. The Molecular Basis for the Functional Selectivity Profile of 2-Bn-Tet-AMPA
2007
Functional Insights from Glutamate Receptor Ion Channel Structures
2012
X-ray structures of AMPA receptor–cone snail toxin complexes illuminate activation mechanism
2014 Science
Enzymatic synthesis of DNA on glycerol nucleic acid templates without stable duplex formation between product and template
2007 StandoutNobel
Enzymatic asymmetric synthesis of chiral amino acids
2018
Emerging structural explanations of ionotropic glutamate receptor function
2004
Cryo-EM structure of the mammalian eukaryotic release factor eRF1–eRF3-associated termination complex
2012 StandoutNobel
Correlating AMPA Receptor Activation and Cleft Closure across Subunits: Crystal Structures of the GluR4 Ligand-Binding Domain in Complex with Full and Partial Agonists
2008
The ribosome and the mechanism of protein synthesis
2006 StandoutNobel
N-Hydroxypyrazolyl Glycine Derivatives as SelectiveN-Methyl-d -aspartic Acid Receptor Ligands
2008
Emerging Targets in Photopharmacology
2016 StandoutNobel
The process of mRNA–tRNA translocation
2007 StandoutNobel
Postsynaptic glutamate receptor δ family contributes to presynaptic terminal differentiation and establishment of synaptic transmission
2009
Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes
2003
Unconventional Secretion, Unconventional Solutions
2013 StandoutScienceNobel
Microsecond-to-Millisecond Conformational Dynamics Demarcate the GluR2 Glutamate Receptor Bound to Agonists Glutamate, Quisqualate, and AMPA
2005
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Self-catalyzed growth of S layers via an amorphous-to-crystalline transition limited by folding kinetics
2010 StandoutNobel
Design, Synthesis, and Pharmacology of a Highly Subtype-Selective GluR1/2 Agonist, (RS)-2-Amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic Acid (Cl-HIBO)
2003
Structure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acid
2005
Quaternary structures of tumor suppressor p53 and a specific p53–DNA complex
2007
Mechanisms of Antagonism of the GluR2 AMPA Receptor: Structure and Dynamics of the Complex of Two Willardiine Antagonists with the Glutamate Binding Domain
2009
Stop Codon Recognition by Release Factors Induces Structural Rearrangement of the Ribosomal Decoding Center that Is Productive for Peptide Release
2007
Works of J.S. Kastrup being referenced
Lessons from crystal structures of kainate receptors
2016
Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate
2011
Full Domain Closure of the Ligand-binding Core of the Ionotropic Glutamate Receptor iGluR5 Induced by the High Affinity Agonist Dysiherbaine and the Functional Antagonist 8,9-Dideoxyneodysiherbaine
2009
Crystal structure of the kainate receptor GluR5 ligand‐binding core in complex with (S)‐glutamate
2005
Structure and Interactions of NCAM Ig1-2-3 Suggest a Novel Zipper Mechanism for Homophilic Adhesion
2003
Distinct Structural Features of Cyclothiazide Are Responsible for Effects on Peak Current Amplitude and Desensitization Kinetics at iGluR2
2009
Lessons from more than 80 structures of the GluA2 ligand-binding domain in complex with agonists, antagonists and allosteric modulators
2010
Modulation of the Dimer Interface at Ionotropic Glutamate-Like Receptor δ2 by d-Serine and Extracellular Calcium
2009
Structural Proof of a Dimeric Positive Modulator Bridging Two Identical AMPA Receptor-Binding Sites
2007
Structural Basis for AMPA Receptor Activation and Ligand Selectivity: Crystal Structures of Five Agonist Complexes with the GluR2 Ligand-binding Core
2002
Structure of a SARS coronavirus-derived peptide bound to the human major histocompatibility complex class I molecule HLA-B*1501
2008
Structural basis of cell-cell adhesion by NCAM.
2000
GluR2 ligand‐binding core complexes: importance of the isoxazolol moiety and 5‐substituent for the binding mode of AMPA‐type agonists
2002
A Helical Structural Nucleus Is the Primary Elongating Unit of Insulin Amyloid Fibrils
2007
The SAXS Solution Structure of RF1 Differs from Its Crystal Structure and Is Similar to Its Ribosome Bound Cryo-EM Structure
2005
Structure of the first PDZ domain of human PSD-93
2009
Molecular mechanism of agonist recognition by the ligand‐binding core of the ionotropic glutamate receptor 4
2008
Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2
2005
Atomic Resolution Structure of Human HBP/CAP37/Azurocidin
1998
High-resolution structure of HLA-A*1101 in complex with SARS nucleocapsid peptide
2005
X-ray Structure of the 154-Amino-Acid Form of Recombinant Human Basic Fibroblast Growth Factor. Comparison with the Truncated 146-Amino-Acid Form
1997
Crystal structure of tetranectin, a trimeric plasminogen‐binding protein with an α‐helical coiled coil
1997
Partial Agonism and Antagonism of the Ionotropic Glutamate Receptor iGLuR5
2007
Structure of the house dust mite allergen Der f 2: Implications for function and molecular basis of IgE cross‐reactivity
2005
Exploring the GluR2 ligand‐binding core in complex with the bicyclical AMPA analogue (S)‐4‐AHCP
2005
A Binding Site Tyrosine Shapes Desensitization Kinetics and Agonist Potency at GluR2
2005
The Structure of a Mixed GluR2 Ligand-binding Core Dimer in Complex with (S)-Glutamate and the Antagonist (S)-NS1209
2006
Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4‐pyridine‐dicarboxylic acid as an in vitro and in cell inhibitor
2012
Structural determinants of agonist-specific kinetics at the ionotropic glutamate receptor 2
2005
Ionotropic glutamate-like receptor δ2 binds d -serine and glycine
2007
Three-Dimensional Structure of the Ligand-Binding Core of GluR2 in Complex with the Agonist (S)-ATPA: Implications for Receptor Subunit Selectivity
2003
Crystal Structure of a Partly Self-Complementary Peptide Nucleic Acid (PNA) Oligomer Showing a Duplex−Triplex Network
2005
Competitive Antagonism of AMPA Receptors by Ligands of Different Classes: Crystal Structure of ATPO Bound to the GluR2 Ligand-Binding Core, in Comparison with DNQX
2002
Thermodynamics and structural analysis of positive allosteric modulation of the ionotropic glutamate receptor GluA2
2011
Chemoenzymatic Synthesis of New 2,4-syn-Functionalized (S)-Glutamate Analogues and Structure–Activity Relationship Studies at Ionotropic Glutamate Receptors and Excitatory Amino Acid Transporters
2013
A Tetrazolyl-Substituted Subtype-Selective AMPA Receptor Agonist
2007
Neuroplastin‐55 binds to and signals through the fibroblast growth factor receptor
2009