Citation Impact
Citing Papers
The Human Tim/Tipin Complex Coordinates an Intra-S Checkpoint Response to UV That Slows Replication Fork Displacement
2007 StandoutNobel
C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion
2014 StandoutNobel
Long Patch Base Excision Repair Proceeds via Coordinated Stimulation of the Multienzyme DNA Repair Complex
2009 StandoutNobel
Saccharomyces cerevisiae MutLα Is a Mismatch Repair Endonuclease
2007 StandoutNobel
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
CRISPR-Cpf1 mediates efficient homology-directed repair and temperature-controlled genome editing
2017 StandoutNobel
Chromatin Reader Brd4 Functions in Ig Class Switching as a Repair Complex Adaptor of Nonhomologous End-Joining
2014 StandoutNobel
The Concept of Synthetic Lethality in the Context of Anticancer Therapy
2005 StandoutNobel
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
2012 StandoutNature
APE1/Ref-1Role in Redox Signaling: Translational Applications of Targeting the Redox Function of the DNA Repair/Redox Protein APE1/Ref-1
2011
Chromatin dynamics and the preservation of genetic information
2007 Nature
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Chromatin Modifications and Their Function
2007 Standout
Classification and evolution of type II CRISPR-Cas systems
2014 StandoutNobel
Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks
2003 Standout
Tying up loose ends: nonhomologous end-joining in Saccharomyces cerevisiae
2000
A Quantitative Systems Approach Reveals Dynamic Control of tRNA Modifications during Cellular Stress
2010
Telomere Dysfunction Increases Mutation Rate and Genomic Instability
2001 StandoutNobel
Ubiquitin Ligase Activity of TFIIH and the Transcriptional Response to DNA Damage
2005 StandoutNobel
Cas9-assisted recombineering in C. elegans : genome editing using in vivo assembly of linear DNAs
2016
Dynamic RNA Modifications in Gene Expression Regulation
2017 Standout
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology
2010
Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork
2005
Human Bloom Protein Stimulates Flap Endonuclease 1 Activity by Resolving DNA Secondary Structure
2004
5 DNA Breakage and Repair
1998
Search-and-replace genome editing without double-strand breaks or donor DNA
2019 StandoutNature
Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α)
2011 StandoutNobel
Genome engineering using the CRISPR-Cas9 system
2013 Standout
Mechanism of Stimulation of Human DNA Ligase I by the Rad9-Rad1-Hus1 Checkpoint Complex
2006 StandoutNobel
Autophagy and Aging
2011 Standout
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
BLM–DNA2–RPA–MRN and EXO1–BLM–RPA–MRN constitute two DNA end resection machineries for human DNA break repair
2011 StandoutNobel
Disruption of the Saccharomyces cerevisiae cell-wall pathway gene SLG1 causes hypersensitivity to the antitumor drug bleomycin
2003
Mechanisms of precise genome editing using oligonucleotide donors
2017
Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA
2016
5-Fluorouracil: mechanisms of action and clinical strategies
2003 Standout
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
Inhibition of Flap Endonuclease 1 by Flap Secondary Structure and Relevance to Repeat Sequence Expansion
2000
Ionizing radiation: how fungi cope, adapt, and exploit with the help of melanin
2008
Balancing instability: dual roles for telomerase and telomere dysfunction in tumorigenesis
2002 StandoutNobel
The role of the ubiquitin/proteasome system in cellular responses to radiation
2003
Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins
2012
Noncanonical DNA Motifs as Transactivation Targets by Wild Type and Mutant p53
2008
Repair of and checkpoint response to topoisomerase I-mediated DNA damage
2003
The Delitto Perfetto Approach to In Vivo Site‐Directed Mutagenesis and Chromosome Rearrangements with Synthetic Oligonucleotides in Yeast
2006
High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
2013 StandoutNobel
Repair of Topoisomerase I‐Mediated DNA Damage
2006
γH2AX and its role in DNA double-strand break repairThis paper is one of a selection of papers published in this Special Issue, entitled 27th International West Coast Chromatin and Chromosome Conference, and has undergone the Journal's usual peer review process.
2006
Human AlkB Homolog ABH8 Is a tRNA Methyltransferase Required for Wobble Uridine Modification and DNA Damage Survival
2010
Antitumor Antibiotics: Bleomycin, Enediynes, and Mitomycin
2005 Standout
Multiple Endonucleases Function to Repair Covalent Topoisomerase I Complexes in Saccharomyces cerevisiae
2005
DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition
2009 Standout
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
The Mre11 Nuclease Is Not Required for 5′ to 3′ Resection at Multiple HO-Induced Double-Strand Breaks
2004
Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems
2013 Standout
Genome-Wide Identification of Genes Conferring Resistance to the Anticancer Agents Cisplatin, Oxaliplatin, and Mitomycin C
2004
Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
2016 StandoutScience
DNA helicase gene interaction network defined using synthetic lethality analyzed by microarray
2003
CRISPR-CasΦ from huge phages is a hypercompact genome editor
2020 StandoutScienceNobel
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Mammalian Sirtuins: Biological Insights and Disease Relevance
2010 Standout
Damage recovery pathways in Saccharomyces cerevisiae revealed by genomic phenotyping and interactome mapping.
2002
Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer
2003 Standout
WRN Helicase and FEN-1 Form a Complex upon Replication Arrest and Together Process Branchmigrating DNA Structures Associated with the Replication Fork
2003
Role of p53 in the Regulation of the Inflammatory Tumor Microenvironment and Tumor Suppression
2018
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Conversion of Topoisomerase I Cleavage Complexes on the Leading Strand of Ribosomal DNA into 5′-Phosphorylated DNA Double-Strand Breaks by Replication Runoff
2000
Simultaneous precise editing of multiple genes in human cells
2019 StandoutNobel
Engineering of temperature- and light-switchable Cas9 variants
2013 StandoutNobel
Flap Endonuclease 1: A Central Component of DNA Metabolism
2004
A yeast‐based complementation assay elucidates the functional impact of 200 missense variants in human PSAT1
2020
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repair
2008 StandoutNobel
Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems
2013 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses.
2001
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
The human Rad9–Rad1–Hus1 checkpoint complex stimulates flap endonuclease 1
2004 StandoutNobel
Yeast Rtt109 Promotes Genome Stability by Acetylating Histone H3 on Lysine 56
2007 Science
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Works of Joyce Snipe being referenced
Genes required for ionizing radiation resistance in yeast
2001
Functional Analysis of Human FEN1 in Saccharomyces Cerevisiae and Its Role in Genome Stability
1999
Conservative Repair of a Chromosomal Double-Strand Break by Single-Strand DNA through Two Steps of Annealing
2006
SIR Functions Are Required for the Toleration of an Unrepaired Double-Strand Break in a Dispensable Yeast Chromosome
2001
Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells
2016
A persistent double-strand break destabilizes human DNA in yeast and can lead to G2 arrest and lethality.
1997
A Single-Nucleotide Polymorphism in a Half-Binding Site Creates p53 and Estrogen Receptor Control of Vascular Endothelial Growth Factor Receptor 1
2007
A Double-Strand Break within a Yeast Artificial Chromosome (YAC) Containing Human DNA Can Result in YAC Loss, Deletion, or Cell Lethality
1996