Standout Papers

Triggering and modulation of apoptosis by oxidative stress 2000 2026 2008 2017 1.1k
  1. Triggering and modulation of apoptosis by oxidative stress (2000)
    Joya Chandra, Afshin Samali et al. Free Radical Biology and Medicine

Citation Impact

Citing Papers

miR-15 and miR-16 induce apoptosis by targeting BCL2
2005 Standout
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Resistance to BRAF Inhibition in BRAF-Mutant Colon Cancer Can Be Overcome with PI3K Inhibition or Demethylating Agents
2012
Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators
2006 Standout
Cell Death Mechanisms and Their Implications in Toxicology
2010
Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
2009 StandoutNature
Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases
2005 Standout
Regulation of cell death: the calcium–apoptosis link
2003 Standout
Identification and Characterization of a New Mammalian Glutaredoxin (Thioltransferase), Grx2
2001
Mitofusin 2 tethers endoplasmic reticulum to mitochondria
2008 StandoutNature
Exercise-Induced Oxidative Stress: Cellular Mechanisms and Impact on Muscle Force Production
2008 Standout
Phospholipid scramblase: An update
2010
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Corpse clearance defines the meaning of cell death
2000 Nature
TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity
2007 StandoutNobel
A receptor for phosphatidylserine-specific clearance of apoptotic cells
2000 Nature
beta2-glycoprotein-I (apolipoprotein H) and beta2-glycoprotein-I-phospholipid complex harbor a recognition site for the endocytic receptor megalin.
1998
The metabolic syndrome
2010 Standout
Bax and Bak Promote Apoptosis by Modulating Endoplasmic Reticular and Mitochondrial Ca2+ Stores
2002
Bcl-2 and calcium: controversy beneath the surface
2004
Thiol-based mechanisms of the thioredoxin and glutaredoxin systems: implications for diseases in the cardiovascular system
2006
β-Cell CaVchannel regulation in physiology and pathophysiology
2004
Cell Death
2004 Standout
NF-κB activation by reactive oxygen species: Fifteen years later
2006
Bcl-2 proteins and calcium signaling: complexity beneath the surface
2016
Calcium and mitochondria in the regulation of cell death
2015
Mitochondria: In Sickness and in Health
2012 Standout
Coupling endoplasmic reticulum stress to the cell death program
2004
The metabolic syndrome
2005 Standout
Review: Nuclear Events in Apoptosis
2000
Apop-1, a Novel Protein Inducing Cyclophilin D-dependent but Bax/Bak-related Channel-independent Apoptosis
2006 StandoutNobel
Phagocytosis of apoptotic cells and the resolution of inflammation
2003
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Free Fatty Acid-induced β-Cell Defects Are Dependent on Uncoupling Protein 2 Expression
2004
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
Pharmaceutical and medicinal significance of sulfur (SVI)-Containing motifs for drug discovery: A critical review
2018 Standout
Mild thermotolerance induced at 40°C increases antioxidants and protects HeLa cells against mitochondrial apoptosis induced by hydrogen peroxide: Role of p53
2009
Oxidative lipidomics of apoptosis: redox catalytic interactions of cytochrome c with cardiolipin and phosphatidylserine
2004
Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis
2010 StandoutNature
Antisense glutaminase inhibition decreases glutathione antioxidant capacity and increases apoptosis in Ehrlich ascitic tumour cells
2004
PGC-1α regulates the mitochondrial antioxidant defense system in vascular endothelial cells
2005
Function of reactive oxygen species during animal development: Passive or active?
2008
Regulation of apoptosis by endoplasmic reticulum pathways
2003
Identification of the haemoglobin scavenger receptor
2001 StandoutNature
Activation of apoptosis signalling pathways by reactive oxygen species
2016 Standout
Origin and physiological roles of inflammation
2008 StandoutNature
Mild thermotolerance induced at 40 °C protects HeLa cells against activation of death receptor-mediated apoptosis by hydrogen peroxide
2010
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
A blast from the past: clearance of apoptotic cells regulates immune responses
2002
Mitochondria
2003
The Pathophysiology and Treatment of Sepsis
2003 Standout
Redox regulation in the lens
2003
The role of phosphatidylserine in recognition of apoptotic cells by phagocytes
1998
Elevated copper and oxidative stress in cancer cells as a target for cancer treatment
2008
The proteasome: a suitable antineoplastic target
2004
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species
2005
Protective effect of 5-hydroxymethylfurfural derived from processed Fructus Corni on human hepatocyte LO2 injured by hydrogen peroxide and its mechanism
2010
Oxidized phospholipids as modulators of inflammation in atherosclerosis
2003
Inflammation, Atherosclerosis, and Coronary Artery Disease
2005 Standout
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Mitochondrial VDAC1: Function in Cell Life and Death and a Target for Cancer Therapy
2012
Overview of cell death signaling pathways
2005
Recognizing death: the phagocytosis of apoptotic cells
1998
APOPTOSIS IN SYSTEMIC LUPUS ERYTHEMATOSUS
2000
Engulfment of apoptotic cells: signals for a good meal
2007
Yeast and mammalian autophagosomes exhibit distinct phosphatidylinositol 3-phosphate asymmetries
2014 StandoutNobel
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
2009 StandoutNature
Clearance of Apoptotic Cells
2004
Inhibition of the Bcr-Abl tyrosine kinase as a therapeutic strategy for CML
2002
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Histone Deacetylase Inhibitors as Anticancer Drugs
2017
The Pathophysiology of Mitochondrial Cell Death
2004 StandoutScience
The Role of Voltage-Gated Calcium Channels in Pancreatic β-Cell Physiology and Pathophysiology
2006
The CD8+ Dendritic Cell Subset Selectively Endocytoses Dying Cells in Culture and In Vivo
2002 StandoutNobel
Expression of Apoptosis-Regulating Proteins in Chronic Lymphocytic Leukemia: Correlations With In Vitro and In Vivo Chemoresponses
1998
AN APPETITE FOR APOPTOTIC CELLS? CONTROVERSIES AND CHALLENGES
2000
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
2006 StandoutNature
Elimination of Hepatic Metastases of Colon Cancer Cells via p53-Independent Cross-Talk between Irinotecan and Apo2 Ligand/TRAIL
2004
Uncoupling Protein 2 Knockout Mice Have Enhanced Insulin Secretory Capacity After a High-Fat Diet
2002
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Nanoparticles in Photodynamic Therapy
2015 Standout
Bcl-2-mediated alterations in endoplasmic reticulum Ca 2+ analyzed with an improved genetically encoded fluorescent sensor
2004 StandoutNobel
Deregulation of the ubiquitin system and p53 proteolysis modify the apoptotic response in B-CLL lymphocytes
2000 StandoutNobel
Thiol redox control via thioredoxin and glutaredoxin systems
2005
Inositol hexakisphosphate suppresses excitatory neurotransmission via synaptotagmin-1 C2B domain in the hippocampal neuron
2012 StandoutNobel
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Mitochondrial Dysfunction and Type 2 Diabetes
2005 StandoutScience
Cancer Genome Landscapes
2013 StandoutScience
Thiol redox control via thioredoxin and glutaredoxin systems
2005
Mechanisms of bacterial lipopolysaccharide-induced endothelial apoptosis
2003
Decoding the Patterns of Self and Nonself by the Innate Immune System
2002 StandoutScience
Glucocorticoid-Induced Plasma Membrane Depolarization during Thymocyte Apoptosis: Association with Cell Shrinkage and Degradation of the Na+/K+-Adenosine Triphosphatase
2001
Bioorthogonal Labeling of Human Prostate Cancer Tissue Slice Cultures for Glycoproteomics
2017 StandoutNobel
Photo-induced treatment of breast epithelial cancer cells using nanostructured titanium dioxide solution
2010
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Multiple Myeloma
2011 Standout
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Deregulation of the ubiquitin system and p53 proteolysis modify the apoptotic response in B-CLL lymphocytes
2000 StandoutNobel
Cellular Stress Responses: Cell Survival and Cell Death
2010
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry
2020 StandoutNobel
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Phosphatidylserine (PS) induces PS receptor–mediated macropinocytosis and promotes clearance of apoptotic cells
2001
The Interplay between the Glucocorticoid Receptor and Nuclear Factor-κB or Activator Protein-1: Molecular Mechanisms for Gene Repression
2003
BAX and BAK Regulation of Endoplasmic Reticulum Ca 2+ : A Control Point for Apoptosis
2003 Science
Hydroxymethylfurfural, A Versatile Platform Chemical Made from Renewable Resources
2013 Standout
Aminophospholipid Asymmetry: A Matter of Life and Death
2003

Works of Joya Chandra being referenced

Synergistic Activity of the Src Family Kinase Inhibitor Dasatinib and Oxaliplatin in Colon Carcinoma Cells Is Mediated by Oxidative Stress
2009
Bax-mediated Ca2+ Mobilization Promotes Cytochrome c Release during Apoptosis
2002
Triggering and modulation of apoptosis by oxidative stress
2000 Standout
Potentiation of reactive oxygen species is a marker for synergistic cytotoxicity of MS-275 and 5-azacytidine in leukemic cells
2007
Effect of novel N-aryl sulfonamide substituted 3-morpholino arecoline derivatives as muscarinic receptor 1 agonists in Alzheimer’s dementia models
2008
Therapeutic Strategies to Enhance the Anticancer Efficacy of Histone Deacetylase Inhibitors
2011
Biological Reactive Intermediates and Mechanisms of Cell Death
2001
Immune Clearance of Phosphatidylserine-expressing Cells by Phagocytes
1997
Cloning and Expression of a Novel Human Glutaredoxin (Grx2) with Mitochondrial and Nuclear Isoforms
2001
Phosphatidylserine Exposure during Apoptosis Is a Cell-Type-Specific Event and Does Not Correlate with Plasma Membrane Phospholipid Scramblase Expression
1999
Apoptosis and the response to anticancer therapy
2001
Role of apoptosis in pancreatic beta-cell death in diabetes.
2001
Effects of the Bcr/abl kinase inhibitors STI571 and adaphostin (NSC 680410) on chronic myelogenous leukemia cells in vitro
2002
Involvement of reactive oxygen species in adaphostin-induced cytotoxicity in human leukemia cells
2003
Apoptosis sensitivity in chronic lymphocytic leukemia is determined by endogenous endonuclease content and relative expression of BCL-2 and BAX
1996
Resistance of leukemic cells to 2-chlorodeoxyadenosine is due to a lack of calcium-dependent cytochrome c release
2002
Effects of serum from patients with type 1 diabetes on primary cerebellar granule cells.
2001
Proteasome Inhibitors Induce Apoptosis in Glucocorticoid-Resistant Chronic Lymphocytic Leukemic Lymphocytes
1998
Protease Activation Is Required for Glucocorticoid-Induced Apoptosis in Chronic Lymphocytic Leukemic Lymphocytes
1997
A Role for Oxidative Stress in Apoptosis: Oxidation and Externalization of Phosphatidylserine Is Required for Macrophage Clearance of Cells Undergoing Fas-Mediated Apoptosis
2002
Rankless by CCL
2026