Citation Impact
Citing Papers
CTLA-4 blockade increases IFNγ-producing CD4 + ICOS hi cells to shift the ratio of effector to regulatory T cells in cancer patients
2008
Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation
2006
A Tlr7 translocation accelerates systemic autoimmunity in murine lupus
2006
Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10–producing suppressive CD4+ T cells
2012
Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus
2009 StandoutNobel
The ICOS/ICOSL Pathway Is Required for Optimal Antitumor Responses Mediated by Anti–CTLA-4 Therapy
2011
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis
2010 Standout
TLR7-dependent and FcγR-independent production of type I interferon in experimental mouse lupus
2008
Neutrophil extracellular traps license macrophages for cytokine production in atherosclerosis
2015 Science
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Neutrophil extracellular traps mediate transfer of cytoplasmic neutrophil antigens to myeloid dendritic cells toward ANCA induction and associated autoimmunity
2012
Recognition of Borrelia burgdorferi , the Lyme Disease Spirochete, by TLR7 and TLR9 Induces a Type I IFN Response by Human Immune Cells
2009
Hallmarks of Cancer: The Next Generation
2011 Standout
Cationic Host Defence Peptides: Potential as Antiviral Therapeutics
2013
The regulation of IL-10 production by immune cells
2010 Standout
A Myeloperoxidase-Containing Complex Regulates Neutrophil Elastase Release and Actin Dynamics during NETosis
2014
Plasmacytoid dendritic cells: key players in the initiation and regulation of immune responses
2010
Netting neutrophils in autoimmune small-vessel vasculitis
2009 Standout
A Critical Reappraisal of Neutrophil Extracellular Traps and NETosis Mimics Based on Differential Requirements for Protein Citrullination
2016
The sweetness of the DNA backbone drives Toll-like receptor 9
2008
Efficient T Cell Activation via a Toll-Interleukin 1 Receptor-Independent Pathway
2006 StandoutNobel
Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes
2012
Control of Toll-like Receptor 7 Expression Is Essential to Restrict Autoimmunity and Dendritic Cell Proliferation
2007
Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity
2008
Psoriasis
2009 Standout
Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease
2016
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
2010 Standout
Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I
2008
Innate Immunity Gone Awry: Linking Microbial Infections to Chronic Inflammation and Cancer
2006
Development of TLR inhibitors for the treatment of autoimmune diseases
2008
TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity
2007 StandoutNobel
The Human Cathelicidin LL-37 Has Antiviral Activity against Respiratory Syncytial Virus
2013 StandoutNobel
The Human Cathelicidin LL-37 Preferentially Promotes Apoptosis of Infected Airway Epithelium
2010
Neutrophil clearance: when the party is over, clean-up begins
2011
Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice
2014
Dendritic Cells
2010
Unraveling the functions of plasmacytoid dendritic cells during viral infections, autoimmunity, and tolerance
2010
LL37 and Cationic Peptides Enhance TLR3 Signaling by Viral Double-stranded RNAs
2011
AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense
2009
Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling
2010 Nature
Ligation of Signal Inhibitory Receptor on Leukocytes-1 Suppresses the Release of Neutrophil Extracellular Traps in Systemic Lupus Erythematosus
2013
Pattern Recognition Receptors and Inflammation
2010 Standout
The roles of TLRs, RLRs and NLRs in pathogen recognition
2009
Cancer immunotherapy via dendritic cells
2012 Standout
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy
2007
Antigen-Presentation Properties of Plasmacytoid Dendritic Cells
2008
Trial watch
2013
STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
2014 Standout
Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909
2005
Toll-like receptors in systemic autoimmune disease
2006
The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells
2008
Two Functional Subsets of FOXP3+ Regulatory T Cells in Human Thymus and Periphery
2008
Intracellular Toll-like Receptors
2010 StandoutNobel
Harnessing human dendritic cell subsets for medicine
2010
Neutrophil extracellular trap formation is increased in psoriasis and induces human β-defensin-2 production in epidermal keratinocytes
2016
Neutrophils in the activation and regulation of innate and adaptive immunity
2011 Standout
DNA released from dying host cells mediates aluminum adjuvant activity
2011
Interleukin-10 production by effector T cells: Th1 cells show self control
2007
Psoriasis pathogenesis and the development of novel targeted immune therapies
2017
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Choreographing Immunity in the Skin Epithelial Barrier
2019
Neutrophil extracellular traps in immunity and disease
2017 Standout
How dying cells alert the immune system to danger
2008
Nucleic acid agonists for Toll‐like receptor 7 are defined by the presence of uridine ribonucleotides
2006
The DNA Sugar Backbone 2′ Deoxyribose Determines Toll-like Receptor 9 Activation
2008
The Human Antimicrobial Peptide LL-37, but Not the Mouse Ortholog, mCRAMP, Can Stimulate Signaling by Poly(I:C) through a FPRL1-dependent Pathway
2013
Type I Interferon in Systemic Lupus Erythematosus and Other Autoimmune Diseases
2006
Ligand-induced conformational changes allosterically activate Toll-like receptor 9
2007
Spontaneous Formation of Nucleic Acid-based Nanoparticles Is Responsible for High Interferon-α Induction by CpG-A in Plasmacytoid Dendritic Cells
2005
A cell biological view of Toll-like receptor function: regulation through compartmentalization
2009
Dendritic cell subsets in health and disease
2007
How to improve the immunogenicity of chemotherapy and radiotherapy
2011
Antiviral Activity and Increased Host Defense against Influenza Infection Elicited by the Human Cathelicidin LL-37
2011
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Antitumor applications of stimulating toll-like receptor 9 with CpG oligodeoxynucleotides
2004
A calculated response: control of inflammation by the innate immune system
2008
Autoimmunity Initiates in Nonhematopoietic Cells and Progresses via Lymphocytes in an Interferon-Dependent Autoimmune Disease
2012
Dendritic Cells In Vivo: A Key Target for a New Vaccine Science
2008 StandoutNobel
Origin and physiological roles of inflammation
2008 StandoutNature
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
The origins and functions of dendritic cells and macrophages in the skin
2014
Innate immune recognition of nucleic acids: Beyond toll-like receptors
2005
Toll-like Receptor 7 and TLR9 Dictate Autoantibody Specificity and Have Opposing Inflammatory and Regulatory Roles in a Murine Model of Lupus
2006
Critical Role for Asparagine Endopeptidase in Endocytic Toll-like Receptor Signaling in Dendritic Cells
2009
Dendritic cells – why can they help and hurt us
2009
Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation
2017
Oxidative Damage of DNA Confers Resistance to Cytosolic Nuclease TREX1 Degradation and Potentiates STING-Dependent Immune Sensing
2013
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
Immunity to fungal infections
2011 Standout
Diversity in the contribution of interleukin‐10 to T‐cell‐mediated immune regulation
2008
Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus
2013
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Toll-like receptor 9-independent aggravation of glomerulonephritis in a novel model of SLE
2006
TH1 cells control themselves by producing interleukin-10
2007
Inducible costimulator (ICOS) is a marker for highly suppressive antigen-specific T cells sharing features of TH17/TH1 and regulatory T cells
2010
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Interleukin-10 Production by Th1 Cells Requires Interleukin-12-Induced STAT4 Transcription Factor and ERK MAP Kinase Activation by High Antigen Dose
2009
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Neutrophil Extracellular Traps Directly Induce Epithelial and Endothelial Cell Death: A Predominant Role of Histones
2012
Plasmacytoid dendritic cells have a cytokine-producing capacity to enhance ICOS ligand-mediated IL-10 production during T-cell priming
2012
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
2010 StandoutNobel
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
Signal Inhibitory Receptor on Leukocytes-1 Limits the Formation of Neutrophil Extracellular Traps, but Preserves Intracellular Bacterial Killing
2016
IgA Enhances NETosis and Release of Neutrophil Extracellular Traps by Polymorphonuclear Cells via Fcα Receptor I
2014
Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3 high regulatory T cells in humans
2015 StandoutNobel
Autoantibodies make a U-turn
2005
Neutrophil Proteases Promote Experimental Abdominal Aortic Aneurysm via Extracellular Trap Release and Plasmacytoid Dendritic Cell Activation
2016
The inhibitory effect of secretory leukocyte protease inhibitor (SLPI) on formation of neutrophil extracellular traps
2015
Netting Neutrophils Are Major Inducers of Type I IFN Production in Pediatric Systemic Lupus Erythematosus
2011
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing
2009 StandoutNobel
A Genomic Approach to Human Autoimmune Diseases
2010
Protein–DNA Complex Is the Exclusive Malaria Parasite Component That Activates Dendritic Cells and Triggers Innate Immune Responses
2010
Immunologically Active Autoantigens: The Role of Toll-Like Receptors in the Development of Chronic Inflammatory Disease
2007
Integrated NY-ESO-1 antibody and CD8+T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab
2011 StandoutNobel
Contrasting roles for all-trans retinoic acid in TGF-β–mediated induction of Foxp3 and Il10 genes in developing regulatory T cells
2009
U1 small nuclear ribonucleoprotein immune complexes induce type I interferon in plasmacytoid dendritic cells through TLR7
2005
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
2011 StandoutNobel
Peptidylarginine Deiminase Inhibition Reduces Vascular Damage and Modulates Innate Immune Responses in Murine Models of Atherosclerosis
2014
Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease
2014
Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9
2010
ICOS+Foxp3+TILs in gastric cancer are prognostic markers and effector regulatory T cells associated withHelicobacter pylori
2016 StandoutNobel
NET formation can occur independently of RIPK3 and MLKL signaling
2015
TLR accessory molecules
2008
Macrophage Clearance of Neutrophil Extracellular Traps Is a Silent Process
2013
Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus
2011
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
Cathepsins are required for Toll-like receptor 9 responses
2008
TLR9 traffics through the Golgi complex to localize to endolysosomes and respond to CpG DNA
2008
Flavivirus Activation of Plasmacytoid Dendritic Cells Delineates Key Elements of TLR7 Signaling beyond Endosomal Recognition
2006
NADPH Oxidase Inhibits the Pathogenesis of Systemic Lupus Erythematosus
2012
Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophages
2009
Neutrophil extracellular traps exacerbate Th1‐mediated autoimmune responses in rheumatoid arthritis by promoting DC maturation
2016
Unique potential of 4-1BB agonist antibody to promote durable regression of HPV + tumors when combined with an E6/E7 peptide vaccine
2015 StandoutNobel
The future of immune checkpoint therapy
2015 StandoutScienceNobel
Wound Healing: A Cellular Perspective
2018 Standout
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Increased Neutrophil Elastase and Proteinase 3 and Augmented NETosis Are Closely Associated With β-Cell Autoimmunity in Patients With Type 1 Diabetes
2014
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Clonal expansion of CD8 T cells in the systemic circulation precedes development of ipilimumab-induced toxicities
2016 StandoutNobel
Immobilized Immune Complexes Induce Neutrophil Extracellular Trap Release by Human Neutrophil Granulocytes via FcγRIIIB and Mac-1
2014
CTLA-4 blockade enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma patients with clinical benefit
2008 StandoutNobel
Role of plasmacytoid dendritic cells and inducible costimulator‐positive regulatory T cells in the immunosuppression microenvironment of gastric cancer
2013
NETosis: how vital is it?
2013
Adjuvant-Enhanced Antibody Responses in the Absence of Toll-Like Receptor Signaling
2006 StandoutScienceNobel
Neutrophil extracellular trap formation is associated with autophagy-related signalling in ANCA-associated vasculitis
2015
Antibody to Langerin/CD207 localizes large numbers of CD8α + dendritic cells to the marginal zone of mouse spleen
2009 StandoutNobel
Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction
2009
NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis
2013
Deoxycytidyl-Deoxyguanosine Oligonucleotide Classes A, B, and C Induce Distinct Cytokine Gene Expression Patterns in Rhesus Monkey Peripheral Blood Mononuclear Cells and Distinct Alpha Interferon Responses in TLR9-Expressing Rhesus Monkey Plasmacytoid Dendritic Cells
2005
IL-2 therapy promotes suppressive ICOS+ Treg expansion in melanoma patients
2013
Works of Josh Gregorio being referenced
Plasmacytoid Dendritic Cells Promote Immunosuppression in Ovarian Cancer via ICOS Costimulation of Foxp3+ T-Regulatory Cells
2012
Self-RNA–antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8
2009
Plasmacytoid dendritic cells prime IL-10–producing T regulatory cells by inducible costimulator ligand
2007
Generation of IL-23 Producing Dendritic Cells (DCs) by Airborne Fungi Regulates Fungal Pathogenicity via the Induction of TH-17 Responses
2010
Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide
2007 Nature
A minimal human immunostimulatory CpG motif that potently induces IFN‐γ and IFN‐α production
2003
Identification of a novel CpG DNA class and motif that optimally stimulate B cell and plasmacytoid dendritic cell functions
2003
Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons
2010
Cytosolic sensing of extracellular self-DNA transported into monocytes by the antimicrobial peptide LL37
2012
Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA–Peptide Complexes in Systemic Lupus Erythematosus
2011
Inhibitors of TLR-9 Act on Multiple Cell Subsets in Mouse and Man In Vitro and Prevent Death In Vivo from Systemic Inflammation
2005
Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus
2005