Citation Impact
Citing Papers
Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program
2007 StandoutNobel
A hexahistidine-Zn 2+ -dye label reveals STIM1 surface exposure
2007 StandoutNobel
MicroRNA-155 is induced during the macrophage inflammatory response
2007 StandoutNobel
Plasmacytoid Dendritic Cell Dynamics and Alpha Interferon Production during Simian Immunodeficiency Virus Infection with a Nonpathogenic Outcome
2008 StandoutNobel
Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients
2007 StandoutNobel
Bacterial CpG-DNA activates dendritic cellsin vivo: T helper cell-independent cytotoxic T cell responses to soluble proteins
2000
The MyD88-Dependent, but Not the MyD88-Independent, Pathway of TLR4 Signaling Is Important in Clearing Nontypeable Haemophilus influenzae from the Mouse Lung
2005 StandoutNobel
IRF-7 is the master regulator of type-I interferon-dependent immune responses
2005 StandoutNature
Ischemia and reperfusion—from mechanism to translation
2011 Standout
Innate immune sensing and its roots: the story of endotoxin
2003 StandoutNobel
A Systematic Review of the Effect of Rotavirus Vaccination on Diarrhea Outcomes Among Children Younger Than 5 Years
2016
Infectious Diseases Society of America/American Thoracic Society Consensus Guidelines on the Management of Community-Acquired Pneumonia in Adults
2007 Standout
Human Enteric Defensins
1996
mRNA Is an Endogenous Ligand for Toll-like Receptor 3
2004 StandoutNobel
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Immunotherapeutic uses of CpG oligodeoxynucleotides
2004
Global, regional, and national causes of under-5 mortality in 2000–15: an updated systematic analysis with implications for the Sustainable Development Goals
2016 Standout
A robust cell culture system supporting the complete life cycle of hepatitis B virus
2017 StandoutNobel
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
Interleukin-12 and the regulation of innate resistance and adaptive immunity
2003 Standout
TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity
2007 StandoutNobel
Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines
2023 StandoutNobel
Nonsevere Community-Acquired Pneumonia
2001
Synthesis of 2-alkoxy-8-hydroxyadenylpeptides: Towards synthetic epitope-based vaccines
2006
Toll-like receptor control of the adaptive immune responses
2004 Standout
Regulation of the T cell response
2006
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
T regulatory cells and the control of allergic disease
2006
Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma
2005
Molecular mechanisms of autoimmunity triggered by microbial infection.
2005
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
2007 StandoutNature
Antiinfective Applications of Toll-like Receptor 9 Agonists
2007
Peptides conjugated to gold nanoparticles induce macrophage activation
2008
Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909
2005
The immunobiology of the TLR9 subfamily
2004
Mechanisms of allergen-specific immunotherapy
2011
Vaccine Adjuvants: Putting Innate Immunity to Work
2010
Skeletal infections: microbial pathogenesis, immunity and clinical management
2022 Standout
Development of TLR9 agonists for cancer therapy
2007
Efficacy and tolerability of once-daily oral telithromycin compared with clarithromycin for the treatment of community-acquired pneumonia in adults
2004
Efficacy of an Adjuvanted Herpes Zoster Subunit Vaccine in Older Adults
2015 Standout
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
CpG-DNA aided cross-presentation of soluble antigens by dendritic cells
2002
Therapeutic implications of the TLR and VDR partnership
2007
The development of allergic inflammation
2008 StandoutNature
Clinical and bacteriological efficacy and safety of 5 and 7 day regimens of telithromycin once daily compared with a 10 day regimen of clarithromycin twice daily in patients with mild to moderate community-acquired pneumonia
2004
Interactions between bacterial CpG-DNA and TLR9 bridge innate and adaptive immunity
2002
Type I interferon is required to mount an adaptive response to immunostimulatory DNA
2001
Antitumor applications of stimulating toll-like receptor 9 with CpG oligodeoxynucleotides
2004
Genetic adjuvants for DNA vaccines
2001
Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists
2007
Community-acquired pneumonia: impact of immune status.
1995
Therapeutics targeting the innate immune system
2004
Mechanisms of allergen-specific immunotherapy
2007
Multiple Sclerosis
2000 Standout
CpG oligonucleotides induce strong humoral but only weak CD4+ T cell responses to protein antigens in rhesus macaques in vivo
2005 StandoutNobel
Targeting Immunosupportive Cancer Therapies: Accentuate the Positive, Eliminate the Negative
2007 StandoutNobel
The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells
2008 StandoutNobel
Community-acquired pneumonia
1998
Immunological mechanisms of allergen-specific immunotherapy
2006
Gold nanoparticles in biomedical applications: recent advances and perspectives
2011 Standout
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Pathogen Recognition and Innate Immunity
2006 Standout
Induction of Systemic TH1-Like Innate Immunity in Normal Volunteers Following Subcutaneous but Not Intravenous Administration of CPG 7909, a Synthetic B-Class CpG Oligodeoxynucleotide TLR9 Agonist
2004
Multiple sclerosis
2002 Standout
Human Peripheral Blood Cells Differentially Recognize and Respond to Two Distinct CpG Motifs
2001
Induction of Broad CD4+and CD8+T-Cell Responses and Cross- Neutralizing Antibodies against Hepatitis C Virus by Vaccination with Th1-Adjuvanted Polypeptides Followed by Defective Alphaviral Particles Expressing Envelope Glycoproteins gpE1 and gpE2 and Nonstructural Proteins 3, 4, and 5
2008 StandoutNobel
Targeted Protein Functionalization Using His-Tags
2004
Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses
2009 Standout
Tissue-Specific Inducible Expression of Antimicrobial Peptide Genes in Drosophila Surface Epithelia
2000 StandoutNobel
Adjuvants and autoimmunity
2009
Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing
2009 StandoutNobel
Campylobacter Enteritis
1981
Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators
2016
Integrated NY-ESO-1 antibody and CD8+T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab
2011 StandoutNobel
Roles of Interleukin-12 and Gamma Interferon in MurineChlamydia pneumoniaeInfection
2000
Dendritic Cells Induce Peripheral T Cell Unresponsiveness under Steady State Conditions in Vivo
2001 StandoutNobel
Present and future therapies of hepatitis B: From discovery to cure
2015
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
2011 StandoutNobel
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans
2011 StandoutNobel
The Linkage of Innate to Adaptive Immunity via Maturing Dendritic Cells In Vivo Requires CD40 Ligation in Addition to Antigen Presentation and CD80/86 Costimulation
2004 StandoutNobel
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Chlamydia pneumoniae infection of the central nervous system in multiple sclerosis
1999
Immunization with HIV-1 Gag Protein Conjugated to a TLR7/8 Agonist Results in the Generation of HIV-1 Gag-Specific Th1 and CD8+ T Cell Responses
2005
Efficient Targeting of Protein Antigen to the Dendritic Cell Receptor DEC-205 in the Steady State Leads to Antigen Presentation on Major Histocompatibility Complex Class I Products and Peripheral CD8+ T Cell Tolerance
2002 StandoutNobel
Plasmacytoid Dendritic Cells Control TLR7 Sensitivity of Naive B Cells via Type I IFN
2005
A New RNA-Based Adjuvant Enhances Virus-Specific Vaccine Responses by Locally Triggering TLR- and RLH-Dependent Effects
2017
Immunostimulatory RNA oligonucleotides trigger an antigen-specific cytotoxic T-cell and IgG2a response
2006
Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8 + T cells
2010 StandoutNobel
Tolerogenic Dendritic Cells
2003 StandoutNobel
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
UNIDENTIFIED CURVED BACILLI IN THE STOMACH OF PATIENTS WITH GASTRITIS AND PEPTIC ULCERATION
1984 Standout
From Allergen Genes to Allergy Vaccines
2010
Local Delivery of CpG Oligodeoxynucleotides Induces Rapid Changes in the Genital Mucosa and Inhibits Replication, but Not Entry, of Herpes Simplex Virus Type 2
2003
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
Antimicrobial Resistance in ESKAPE Pathogens
2020 Standout
Deoxycytidyl-Deoxyguanosine Oligonucleotide Classes A, B, and C Induce Distinct Cytokine Gene Expression Patterns in Rhesus Monkey Peripheral Blood Mononuclear Cells and Distinct Alpha Interferon Responses in TLR9-Expressing Rhesus Monkey Plasmacytoid Dendritic Cells
2005
Works of Joseph Eiden being referenced
Comparison of the safety and immunogenicity of hepatitis B virus surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide and a licensed hepatitis B vaccine in healthy young adults
2005
Safety, tolerability, and immunogenicity of a single dose 4-antigen or 3-antigen Staphylococcus aureus vaccine in healthy older adults: Results of a randomised trial
2016
Amb a 1–immunostimulatory oligodeoxynucleotide conjugate immunotherapy decreases the nasal inflammatory response
2004
Diagnosis of Chlamydia pneumoniae Infection in Patients with Community-Acquired Pneumonia by Polymerase Chain Reaction Enzyme Immunoassay
1994
Immunotherapy with a Ragweed–Toll-Like Receptor 9 Agonist Vaccine for Allergic Rhinitis
2006
Selective immune redirection in humans with ragweed allergy by injecting Amb a 1 linked to immunostimulatory DNA
2004
A phase I study of the safety and immunogenicity of recombinant hepatitis B surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide adjuvant
2003
Safety, efficacy, and immunogenicity of a live, quadrivalent human-bovine reassortant rotavirus vaccine in healthy infants
2004
Use of Immunostimulatory Sequence-Containing Oligonucleotides as Topical Therapy for Genital Herpes Simplex Virus Type 2 Infection
2002
Enteric Infectious Disease in Neonates
1994
Conjugation of protein to immunostimulatory DNA results in a rapid, long‐lasting and potent induction of cell‐mediated and humoral immunity
2000
Persistence of Immune Responses Through 36 Months in Healthy Adults After Vaccination With a Novel Staphylococcus aureus 4-Antigen Vaccine (SA4Ag)
2019
Campylobacter fetus subspecies jejuni Bacteremia
1980