Citation Impact
Citing Papers
Multiplex Genome Engineering Using CRISPR/Cas Systems
2013 StandoutScience
Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro
2006 StandoutNobel
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
Neutralizing antibody response during acute and chronic hepatitis C virus infection
2004 StandoutNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Mouse ribonuclease III. cDNA structure, expression analysis, and chromosomal location
2002
A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer
2014
Directed evolution improves the catalytic efficiency of TEV protease
2019
SEC14L2 enables pan-genotype HCV replication in cell culture
2015 StandoutNatureNobel
Atomic model of the type III secretion system needle
2012 StandoutNatureNobel
A scoutRNA Is Required for Some Type V CRISPR-Cas Systems
2020 StandoutNobel
Crystal structure of human DGCR8 core
2007
Modular and tunable biological feedback control using a de novo protein switch
2019 StandoutNatureNobel
Regulation of microRNA biogenesis
2014 Standout
Identification of endoribonuclease specific cleavage positions reveals novel targets of RNase III inStreptococcus pyogenes
2017 StandoutNobel
Making and Breaking Nucleic Acids: Two-Mg2+-Ion Catalysis and Substrate Specificity
2006
A combined approach to improving large-scale production of tobacco etch virus protease
2007
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
RNAi: an ever-growing puzzle
2003
Structure of the Human Dicer-TRBP Complex by Electron Microscopy
2009
MicroRNAs: small RNAs with a big role in gene regulation
2004 Standout
Characterization of RNA sequence determinants and antideterminants of processing reactivity for a minimal substrate of Escherichia coli ribonuclease III
2006
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
2011 StandoutNatureNobel
Protein refolding is required for assembly of the type three secretion needle
2010
MicroRNA biogenesis: coordinated cropping and dicing
2005 Standout
The Human DiGeorge Syndrome Critical Region Gene 8 and Its D. melanogaster Homolog Are Required for miRNA Biogenesis
2004
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
RNase III enzymes and the initiation of gene silencing
2004
Expanded Utility of the Native Chemical Ligation Reaction
2004
Mapping of internal monophosphate 5′ ends ofBacillus subtilismessenger RNAs and ribosomal RNAs in wild-type and ribonuclease-mutant strains
2016
Analysis of the C. elegans Argonaute Family Reveals that Distinct Argonautes Act Sequentially during RNAi
2006 StandoutNobel
Structural determinants of RNA recognition and cleavage by Dicer
2007 StandoutNobel
Distinct Roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA Silencing Pathways
2004
Thirty-Three Years Later, a Glimpse at the Ribonuclease III Active Site
2001
The karyogamy gene KAR2 and novel proteins are required for ER-membrane fusion
1994 StandoutNobel
Can Morphing Methods Predict Intermediate Structures?
2008 StandoutNobel
The Structure of Human Argonaute-2 in Complex with miR-20a
2012
Structure of the nuclease domain of ribonuclease III from M. tuberculosis at 2.1 Å
2005
The Acidic Transcription Activator Gcn4 Binds the Mediator Subunit Gal11/Med15 Using a Simple Protein Interface Forming a Fuzzy Complex
2011 StandoutNobel
The type III secretion injectisome
2006
The Continuing Story of Endoribonuclease III
2004
Optimized Torsion-Angle Normal Modes Reproduce Conformational Changes More Accurately Than Cartesian Modes
2011 StandoutNobel
RNA structure-dependent uncoupling of substrate recognition and cleavage by Escherichia coli ribonuclease III
2003
Catalytic mechanism of Escherichia coli ribonuclease III: kinetic and inhibitor evidence for the involvement of two magnesium ions in RNA phosphodiester hydrolysis
2005
Mini‐III, an unusual member of the RNase III family of enzymes, catalyses 23S ribosomal RNA maturation in B. subtilis
2008
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
RNA sequencing uncovers antisense RNAs and novel small RNAs inStreptococcus pyogenes
2015 StandoutNobel
RNA interference
2002 StandoutNature
The bacterial injection kit: Type III secretion systems
2005
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets
2014 Standout
Design of fast proteolysis-based signaling and logic circuits in mammalian cells
2018
Dicer is essential for mouse development
2003 Standout
Molecular Basis for the Recognition of Primary microRNAs by the Drosha-DGCR8 Complex
2006
Protein delivery into eukaryotic cells by type III secretion machines
2006 Nature
Global Regulatory Functions of the Staphylococcus aureus Endoribonuclease III in Gene Expression
2012
Regulation of Escherichia coli RNase III activity
2015
Nucleases: diversity of structure, function and mechanism
2010
A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans
2004 StandoutNatureNobel
miRNAs on the move: miRNA biogenesis and the RNAi machinery
2004
The Drosha-DGCR8 complex in primary microRNA processing
2004 Standout
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Biogenesis of small RNAs in animals
2009 Standout
Single Processing Center Models for Human Dicer and Bacterial RNase III
2004
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
2013 StandoutNobel
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles
2003 StandoutNobel
Sequencing of metals in multivariate metal-organic frameworks
2020 StandoutScienceNobel
A Cas9–guide RNA complex preorganized for target DNA recognition
2015 StandoutScienceNobel
Improving Protein Expression, Stability, and Function with ProteinMPNN
2024 StandoutNobel
Role of MicroRNAs in Plant and Animal Development
2003 StandoutScienceNobel
Mechanism of Mediator Recruitment by Tandem Gcn4 Activation Domains and Three Gal11 Activator-Binding Domains
2010
Seven Post-synthetic Covalent Reactions in Tandem Leading to Enzyme-like Complexity within Metal–Organic Framework Crystals
2016 StandoutNobel
Chemical Glycobiology
2001 StandoutScienceNobel
Ribonuclease III mechanisms of double‐stranded RNA cleavage
2013
Fucosylation and protein glycosylation create functional receptors for cholera toxin
2015
Pneumococcal Neuraminidase Substrates Identified through Comparative Proteomics Enabled by Chemoselective Labeling
2016
Update 1 of: Proteases Universally Recognize Beta Strands In Their Active Sites
2010
In vitro reconstitution of the human RISC-loading complex
2008 StandoutNobel
Engineering Translational Activators with CRISPR-Cas System
2015
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
Structural and Biochemical Studies of a Fluoroacetyl-CoA-Specific Thioesterase Reveal a Molecular Basis for Fluorine Selectivity
2010 StandoutNobel
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
Programmable protein circuits in living cells
2018 Science
What's the point of the type III secretion system needle?
2008
Differential inhibition of multiple vesicular transport steps between the endoplasmic reticulum and trans Golgi network.
1993
Structural Basis for Double-Stranded RNA Processing by Dicer
2006 StandoutScienceNobel
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Decoding complex order in reticular frameworks
2023 StandoutScienceNobel
De novo design of protein logic gates
2020 StandoutScienceNobel
Chemical Glycoproteomics
2016 StandoutNobel
Synthesis and Biological Activity of Natural Aminocyclopentitol Glycosidase Inhibitors: Mannostatins, Trehazolin, Allosamidins, and Their Analogues
1999
Protein N-Glycosylation: Molecular Genetics and Functional Significance
1998
Works of Joseph E. Tropea being referenced
Structure of theYersinia pestistype III secretion chaperone SycH in complex with a stable fragment of YscM2
2004
Differential temperature dependence of tobacco etch virus and rhinovirus 3C proteases
2013
Structural Insight into the Mechanism of Double-Stranded RNA Processing by Ribonuclease III
2006
Structural Basis for the Substrate Specificity of Tobacco Etch Virus Protease
2002
Crystal structure of the Yersinia pestis GTPase activator YopE
2002
Three-dimensional structure of the type III secretion chaperone SycE fromYersinia pestis
2002
Structural Characterization of the Yersinia pestis Type III Secretion System Needle Protein YscF in Complex with Its Heterodimeric Chaperone YscE/YscG
2008
Three-dimensional Structure of a Macromolecular Assembly that Regulates Type III Secretion in Yersinia pestis
2004
Novel Protein-Protein Interactions of the Yersinia pestis Type III Secretion System Elucidated with a Matrix Analysis by Surface Plasmon Resonance and Mass Spectrometry
2004
Noncatalytic Assembly of Ribonuclease III with Double-Stranded RNA
2004
Similar modes of polypeptide recognition by export chaperones in flagellar biosynthesis and type III secretion
2003
Structural Basis for p300 Taz2-p53 TAD1 Binding and Modulation by Phosphorylation
2009
Crystallographic and Modeling Studies of RNase III Suggest a Mechanism for Double-Stranded RNA Cleavage
2001
Expression and Purification of Soluble His6-Tagged TEV Protease
2008
Efficient site-specific processing of fusion proteins by tobacco vein mottling virus protease in vivo and in vitro
2004
The Catalytic Domain of Escherichia coli Lon Protease Has a Unique Fold and a Ser-Lys Dyad in the Active Site
2004
Intermediate States of Ribonuclease III in Complex with Double-Stranded RNA
2005
Mannostatin A, a new glycoprotein-processing inhibitor
1990
Comparison of the substrate specificity of two potyvirus proteases
2004
A stepwise model for double‐stranded RNA processing by ribonuclease III
2007
Kifunensine, a potent inhibitor of the glycoprotein processing mannosidase I.
1990
Two Distinct Motifs within the p53 Transactivation Domain Bind to the Taz2 Domain of p300 and Are Differentially Affected by Phosphorylation
2009
Tobacco Etch Virus Protease: Crystal Structure of the Active Enzyme and Its Inactive Mutant
2003
RNase III: Genetics and Function; Structure and Mechanism
2013