Citation Impact
Citing Papers
Chapter 8. Tissue acidosis in nociception and pain
1996
Crystal structure of a replication fork single-stranded DNA binding protein (T4 gp32) complexed to DNA
1995 StandoutNatureNobel
U1-snRNP-A protein selects a ten nucleotide consensus sequence from a degenerate RNA pool presented in various structural contexts
1991
RNA binding specificity of aDrosophilasnRNP protein that shares sequence homology with mammalian U1-A and U2-B’ proteins
1992
A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein
1989
Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly
2001 Nature
MicroRNAs
2004 Standout
Snurportin1, an m3G-cap-specific nuclear import receptor with a novel domain structure
1998
Nuclear export of proteins and RNAs
1997
TAP, the Human Homolog of Mex67p, Mediates CTE-Dependent RNA Export from the Nucleus
1998
Concerted activities of the RNA recognition and the glycine‐rich C‐terminal domains of nucleolin are required for efficient complex formation with pre‐ribosomal RNA
1992
Identification of a signal for rapid export of proteins from the nucleus
1995 StandoutNobel
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Nuclear RNA export
1998 StandoutNobel
Translocation of a specific premessenger ribonucleoprotein particle through the nuclear pore studied with electron microscope tomography
1992
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
The structure of ribosomal protein S5 reveals sites of interaction with 16S rRNA
1992 StandoutNatureNobel
Nuclear transport of influenza virus ribonucleoproteins: The viral matrix protein (M1) promotes export and inhibits import
1991
Nuclear Export Pathways of tRNA and 40 S Ribosomes Include both Common and Specific Intermediates
1995
The Cold Shock Domain Protein LIN-28 Controls Developmental Timing in C. elegans and Is Regulated by the lin-4 RNA
1997 StandoutNobel
RNA and DNA binding zinc fingers in Xenopus TFIIIA
1992
A Distinct Nuclear Import Pathway Used by Ribosomal Proteins
1997 StandoutNobel
A weak interaction between the U2A′ protein and U2 snRNA helps to stabilize their complex with the U2B” protein
1991
The Balbiani ring particle: a model for the assembly and export of RNPs from the nucleus?
1993
A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for the catalytic activation of the spliceosome
1992
RNA Export
1995
The two steps of nuclear import, targeting to the nuclear envelope and translocation through the nuclear pore, require different cytosolic factors
1992 StandoutNobel
Interaction of RNA Hairpins with the Human U1A N-Terminal RNA Binding Domain
1994
Nuclear import-export: In search of signals and mechanisms
1991
Antisense probes containing 2-aminoadenosine allow efficient depletion of U5 snRNP from HeLa splicing extracts
1991
Quality control of mRNA 3′-end processing is linked to the nuclear exosome
2001 StandoutNatureNobel
Dbp5p/Rat8p is a yeast nuclear pore-associated DEAD-box protein essential for RNA export
1998
The U1 snRNP protein U1C recognizes the 5′ splice site in the absence of base pairing
2002 StandoutNatureNobel
Proton, carbon-13, and nitrogen-15 NMR assignments and global folding pattern of the RNA-binding domain of the human hnRNP C proteins
1992
Staufen protein associates with the 3′UTR of bicoid mRNA to form particles that move in a microtubule-dependent manner
1994 StandoutNobel
Transcription units as RNA processing units
1997
Viral and cellular mRNA capping: Past and prospects
2000
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
1993 StandoutNobel
Pathways for the nuclear transport of proteins and RNAs
1991
Crystal Structures of Two Sm Protein Complexes and Their Implications for the Assembly of the Spliceosomal snRNPs
1999
A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain
2011 StandoutNatureNobel
Biochemical Mechanisms of Constitutive and Regulated Pre-mRNA Splicing
1991
A Biochemical Function for the Sm Complex
2001 StandoutNobel
HIV-1 Genome Nuclear Import Is Mediated by a Central DNA Flap
2000 StandoutNobel
Antisense probing of the human U4U6 snRNP with biotinylated 2′-OMe RNA oligonucleotides
1989
The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathway
1997
Identification of a nuclear export receptor for tRNA
1998
Genetic evidence for base pairing between U2 and U6 snRNA in mammalian mRNA splicing
1991 Nature
Crystal structure at 1.92 Å resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin
1994 Nature
CRM1 Is an Export Receptor for Leucine-Rich Nuclear Export Signals
1997 Standout
The simian retrovirus-1 constitutive transport element, unlike the HIV-1 RRE, uses factors required for cellular mRNA export
1997
Nucleotide sequence and analysis of the centromeric region of yeast chromosome IX
1995
Cytosolic proteins that specifically bind nuclear location signals are receptors for nuclear import
1991
SR proteins can compensate for the loss of U1 snRNP functions in vitro.
1994
The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleus
1997
Nopp 140 shuttles on tracks between nucleolus and cytoplasm
1992 StandoutNobel
The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex
1995 StandoutNobel
Defective Urinary Concentrating Ability Due to a Complete Deficiency of Aquaporin-1
2001 StandoutNobel
Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins
1995 StandoutNobel
Crystal structure of the RNA-binding domain of the U1 small nuclear ribonucleoprotein A
1990 Nature
U5 snRNA interacts with exon sequences at 5′ and 3′ splice sites
1992
Switching and Signaling at the Telomere
2001 StandoutNobel
Alteration of the RNA polymerase specificity of U3 snRNA genes during evolution and in vitro
1991
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Major determinants of the specificity of interaction between small nuclear ribonucleoproteins U1A and U2B" and their cognate RNAs
1990 Nature
Acid-sensing ion channels: advances, questions and therapeutic opportunities
2006
Cross-Intron Bridging Interactions in the Yeast Commitment Complex Are Conserved in Mammals
1997 StandoutNobel
Targeted snRNP depletion reveals an additional role for mammalian U1 snRNP in spliceosome assembly
1990
Identification and characterization of a yeast homolog of U1 snRNP-specific protein C
1997 StandoutNobel
Structure of the nuclear transport complex karyopherin-β2–Ran˙GppNHp
1999 StandoutNatureNobel
A cap-binding protein complex mediating U snRNA export
1995 Nature
Human U2 snRNA can function in pre-mRNA splicing in yeast
1990 Nature
MicroRNA maturation: stepwise processing and subcellular localization
2002 Standout
A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo
1989 StandoutNobel
The human U1 snRNP-Specific U1A protein inhibits polyadenylation of its own pre-mRNA
1993
Crystal structure of a hepatitis delta virus ribozyme
1998 StandoutNatureNobel
A nuclear cap binding protein complex involved in pre-mRNA splicing
1994
Nup145p is required for nuclear export of mRNA and binds homopolymeric RNA in vitro via a novel conserved motif
1994
RNA recognition: towards identifying determinants of specificity
1991
Nuclear Import and Export of Viruses and Virus Genomes
1998
The HIV-1 Rev Activation Domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs
1995
Nuclear export of proteins: The role of nuclear retention
1993
A Transient, Neuron-Wide Form of CREB-Mediated Long-Term Facilitation Can Be Stabilized at Specific Synapses by Local Protein Synthesis
1999 StandoutNobel
Requirement of Human Renal Water Channel Aquaporin-2 for Vasopressin-dependent Concentration of Urine
1994 Science
Heat-stable inhibitors of cAMP-dependent protein kinase carry a nuclear export signal.
1994 StandoutNobel
Role of the Nuclear Transport Factor p10 in Nuclear Import
1996 StandoutScienceNobel
TheRb97Dgene encodes a potential RNA-binding protein required for spermatogenesis inDrosophila
1993
NUCLEOCYTOPLASMIC TRANSPORT: The Soluble Phase
1998
Structure and Function of the Nuclear Pore Complex
1992
Nucleocytoplasmic transport of macromolecules
1997
Kap104p: A Karyopherin Involved in the Nuclear Transport of Messenger RNA Binding Proteins
1996 StandoutScienceNobel
Direct, sequence-specific binding of the human U1-70K ribonucleoprotein antigen protein to loop I of U1 small nuclear RNA.
1989
The Xenopus laevis poly(A) binding protein is composed of multiple functionally independent RNA binding domains.
1990
G-strings at chromosome ends
1988 StandoutNatureNobel
Mutations in aquaporin-1 in Phenotypically Normal Humans Without Functional CHIP Water Channels
1994 StandoutScienceNobel
Identification of molecular contacts between the U1 A small nuclear ribonucleoprotein and U1 RNA.
1991
A nuclear cap-binding complex binds Balbiani ring pre-mRNA cotranscriptionally and accompanies the ribonucleoprotein particle during nuclear export.
1996
Mature mRNA 3′ end formation stimulates RNA export from the nucleus.
1991
Identification of Prp40, a Novel Essential Yeast Splicing Factor Associated with the U1 Small Nuclear Ribonucleoprotein Particle
1996
Conserved amino acid residues within and outside of the N-terminal ribonucleoprotein motif of U1A small nuclear ribonucleoprotein involved in U1 RNA binding
1991
The snRNP core assembly pathway: identification of stable core protein heteromeric complexes and an snRNP subcore particle in vitro.
1996
The association of the U1-specific 70K and C proteins with U1 snRNPs is mediated in part by common U snRNP proteins.
1994
Diversity in the signals required for nuclear accumulation of U snRNPs and variety in the pathways of nuclear transport.
1991
A conserved double-stranded RNA-binding domain.
1992
In vivo analysis of the stability and transport of nuclear poly(A)+ RNA.
1994
Regulation of mRNA export in response to stress in Saccharomyces cerevisiae.
1996
Inhibition of mRNA export in vertebrate cells by nuclear export signal conjugates
1997
The Vertebrate GLFG Nucleoporin, Nup98, Is an Essential Component of Multiple RNA Export Pathways
1997
Export of mRNA from microinjected nuclei of Xenopus laevis oocytes.
1992
RAN/TC4 mutants identify a common requirement for snRNP and protein import into the nucleus.
1996
A nuclear cap-binding complex facilitates association of U1 snRNP with the cap-proximal 5' splice site.
1996
Inhibition of nuclear protein import by nonhydrolyzable analogues of GTP and identification of the small GTPase Ran/TC4 as an essential transport factor [published erratum appears in J Cell Biol 1994 Jan;124(1-2):217]
1993
Functional Characterization of Nuclear Localization Signals in Yeast Sm Proteins
2000
Helix-turn-helix, zinc-finger, and leucine-zipper motifs for eukaryotic transcriptional regulatory proteins
1989
Isolation and characterization of Saccharomyces cerevisiae mRNA transport-defective (mtr) mutants [published erratum appears in J Cell Biol 1994 Sep;126(6):1627]
1994
An enhancer screen identifies a gene that encodes the yeast U1 snRNP A protein: implications for snRNP protein function in pre-mRNA splicing.
1993 StandoutNobel
RNA-binding domain of the A protein component of the U1 small nuclear ribonucleoprotein analyzed by NMR spectroscopy is structurally similar to ribosomal proteins.
1991
Efficient association of U2 snRNPs with pre-mRNA requires an essential U2 RNA structural element.
1991
The hnRNP C proteins contain a nuclear retention sequence that can override nuclear export signals.
1996
Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm
1992 Nature
Multicolor and Electron Microscopic Imaging of Connexin Trafficking
2002 StandoutScienceNobel
Ribonucleoprotein particles in cellular processes.
1988
Quantitative determination that one of two potential RNA-binding domains of the A protein component of the U1 small nuclear ribonucleoprotein complex binds with high affinity to stem-loop II of U1 RNA.
1990
Identification and Characterization of a Yeast Gene Encoding the U2 Small Nuclear Ribonucleoprotein Particle B″ Protein
1996 StandoutNobel
An RBD that does not bind RNA: NMR secondary structure determination and biochemical properties of the C-terminal RNA binding domain from the human U1A protein
1995
Microinjected U snRNAs are imported to oocyte nuclei via the nuclear pore complex by three distinguishable targeting pathways.
1992
Nuclear export of different classes of RNA is mediated by specific factors
1994
A cap binding protein that may mediate nuclear export of RNA polymerase II-transcribed RNAs.
1992
An analysis of vertebrate mRNA sequences: intimations of translational control.
1991 Standout
U1 Small Nuclear Ribonucleoprotein Particle-Protein Interactions are Revealed in Saccharomyces cerevisiae by In Vivo Competition Assays
1993 StandoutNobel
Structure of spliceosomal snRNPs and their role in pre-mRNA splicing
1990
A yeast protein that bidirectionally affects nucleocytoplasmic transport
1995
The low abundance of U7 snRNA is partly determined by its Sm binding site.
1993
Universally conserved and yeast-specific U1 snRNA sequences are important but not essential for U1 snRNP function.
1990 StandoutNobel
The GTP-binding protein Ran/TC4 is required for protein import into the nucleus
1993 StandoutNatureNobel
U2 snRNA sequences that bind U2-specific proteins are dispensable for the function of U2 snRNP in splicing.
1989
Transport Between the Cell Nucleus and the Cytoplasm
1999 Standout
A conditional yeast mutant deficient in mRNA transport from nucleus to cytoplasm.
1992
Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.
1996
In vitro reconstitution of functional yeast U2 snRNPs.
1989
TAPping into mRNA Export
2001 StandoutScienceNobel
Structurally Related but Functionally Distinct Yeast Sm D Core Small Nuclear Ribonucleoprotein Particle Proteins
1995
RNA TRANSPORT
1997
Mammalian pre-mRNA branch site selection by U2 snRNP involves base pairing.
1989
YEAST GENETICS TO DISSECT THE NUCLEAR PORE COMPLEX AND NUCLEOCYTOPLASMIC TRAFFICKING
1997
The yeast branchpoint sequence is not required for the formation of a stable U1 snRNA-pre-mRNA complex and is recognized in the absence of U2 snRNA.
1991 StandoutNobel
The RNA Component of Human Telomerase
1995 StandoutScienceNobel
Arginine methylation facilitates the nuclear export of hnRNP proteins
1998
A Role for the M9 Transport Signal of hnRNP A1 in mRNA Nuclear Export
1997
Transport of macromolecules between the nucleus and the cytoplasm.
1998
Interactions of Small Nuclear RNA's with Precursor Messenger RNA During in Vitro Splicing
1992 Science
Multiple pathways in nuclear transport: the import of U2 snRNP occurs by a novel kinetic pathway.
1991
Direct interaction of the U1 snRNP-A protein with the upstream efficiency element of the SV40 late polyadenylation signal.
1994
The multiple RNA-binding domains of the mRNA poly(A)-binding protein have different RNA-binding activities.
1991
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Interaction of the RNA-binding domain of the hnRNP C proteins with RNA.
1992
The nematode spliced leader RNA participates in trans-splicing as an Sm snRNP.
1990
The human homologue of Saccharomyces cerevisiae Gle1p is required for poly(A) + RNA export
1998
Isolation and characterization of RAT1: an essential gene of Saccharomyces cerevisiae required for the efficient nucleocytoplasmic trafficking of mRNA.
1992
Intracellular distribution of the U1A protein depends on active transport and nuclear binding to U1 snRNA.
1992
Nucleo-cytoplasmic transport of U snRNPs: definition of a nuclear location signal in the Sm core domain that binds a transport receptor independently of the m3G cap.
1993
Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box.
1992
Conserved Structures and Diversity of Functions of RNA-Binding Proteins
1994 StandoutScience
Role of Polyadenylation in Nucleocytoplasmic Transport of mRNA
1996
Evidence that HIV-1 Rev directly promotes the nuclear export of unspliced RNA.
1994
Functional analysis of pre-mRNA splicing factor SF2/ASF structural domains.
1993
tRNA-like structures tag the 3' ends of genomic RNA molecules for replication: implications for the origin of protein synthesis.
1987
An Essential Signaling Role for the m 3 G Cap in the Transport of U1 snRNP to the Nucleus
1990 Science
mRNA nuclear export
1994 StandoutNobel
Recognition of U1 and U2 small nuclear RNAs can be altered by a 5-amino-acid segment in the U2 small nuclear ribonucleoprotein particle (snRNP) B" protein and through interactions with U2 snRNP-A' protein.
1991
Structural Insights into Group II Intron Catalysis and Branch-Site Selection
2002 StandoutScienceNobel
Messenger RNA Splicing in Yeast: Clues to Why the Spliceosome Is a Ribonucleoprotein
1991 Science
The mouse histone H2a gene contains a small element that facilitates cytoplasmic accumulation of intronless gene transcripts and of unspliced HIV-1-related mRNAs
1997
Works of Jörg Hamm being referenced
The trimethylguanosine cap structure of U1 snRNA is a component of a bipartite nuclear targeting signal
1990
Probing the structure and function of U2 snRNP with antisense oligonucleotides made of 2′-OMe RNA
1989
Monomethylated cap structures facilitate RNA export from the nucleus
1990
In vitro assembly of U1 snRNPs.
1987
An abundant U6 snRNP found in germ cells and embryos of Xenopus laevis.
1989
Loop I of U1 small nuclear RNA is the only essential RNA sequence for binding of specific U1 small nuclear ribonucleoprotein particle proteins.
1988
Regulated splicing in early development and stage-specific U snRNPs
1989
Functional analysis of mutant Xenopus U2 snRNAs
1989
Intracellular pH in human skeletal muscle by 1H NMR.
1988
The 5S gene internal control region is composed of three distinct sequence elements, organized as two functional domains with variable spacing
1987
Functional domains of the Xenopus laevis 5S gene promoter.
1985
Identification of the RNA binding segment of human U1 A protein and definition of its binding site on U1 snRNA.
1989
Loop I of U1 Small Nuclear RNA Is The Only Essential RNA Sequence for Binding of Specific U1 Small Nuclear Ribonucleoprotein Particle Proteins
1988
Transport of RNA between the nucleus and the cytoplasm
1990
Multiple domains of U1 snRNA, including U1 specific protein binding sites, are required for splicing.
1990