Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Cell Type–Specific, Topoisomerase II–Dependent Inhibition of Hypoxia-Inducible Factor-1α Protein Accumulation by NSC 644221
2007
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
Jun activation domain binding protein 1 expression is associated with low p27(Kip1)levels in node-negative breast cancer.
2003
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Prognostic significance of Hypoxia-Inducible Factor 1 alpha(HIF-1alpha) expression in serous ovarian cancer: an immunohistochemical study
2008
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
2019 StandoutNobel
Repression of hypoxia-inducible factor α signaling by Set7-mediated methylation
2015
Mitochondrial reactive oxygen species regulate hypoxic signaling
2009
Sirtuins as regulators of metabolism and healthspan
2012 Standout
HIF prolyl and asparaginyl hydroxylases in the biological response to intracellular O2 levels
2003 StandoutNobel
Nuclear translocation of hypoxia-inducible factors (HIFs): Involvement of the classical importin α/β pathway
2007
Hallmarks of Cancer: The Next Generation
2011 Standout
Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
2024 StandoutNobel
Hypoxia-inducible factor-1α expression in the gastric carcinogenesis sequence and its prognostic role in gastric and gastro-oesophageal adenocarcinomas
2006
PRDX2 and PRDX4 are negative regulators of hypoxia-inducible factors under conditions of prolonged hypoxia
2016 StandoutNobel
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
A Novel Superoxide-producing NAD(P)H Oxidase in Kidney
2001
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
2010 Standout
Redox regulation of the hypoxia-inducible factor
2006
HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression
2011
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
HIF‐1α and HIF‐2α have divergent roles in colon cancer
2008
Regulation and Destabilization of HIF-1α by ARD1-Mediated Acetylation
2002
An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia
2009
Effect of p47phoxgene deletion on ROS production and oxygen sensing in mouse carotid body chemoreceptor cells
2005
Controlling metabolism and cell death: At the heart of mitochondrial calcium signalling
2009
Oxyl radicals, redox-sensitive signalling cascades and antioxidants
2007 Standout
HIF1α Protein Stability Is Increased by Acetylation at Lysine 709
2012
The contribution of VHL substrate binding and HIF1-α to the phenotype of VHL loss in renal cell carcinoma
2002
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
Targeting hypoxia cell signaling for cancer therapy
2007
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
2012 StandoutNatureNobel
Cancer-associated 2-oxoglutarate analogues modify histone methylation by inhibiting histone lysine demethylases
2018
Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer
2007
Sirtuins, Aging, and Metabolism
2011
Inhibition of SIRT1 Impairs the Accumulation and Transcriptional Activity of HIF-1α Protein under Hypoxic Conditions
2012
HIF-1, O2, and the 3 PHDs
2001 StandoutNobel
Inhibition of endogenous HIF inactivation induces angiogenesis in ischaemic skeletal muscles of mice
2004
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Age-dependent Defect in Vascular Endothelial Growth Factor Expression Is Associated with Reduced Hypoxia-inducible Factor 1 Activity
2000 StandoutNobel
SIRT2 regulates tumour hypoxia response by promoting HIF-1α hydroxylation
2014
Monoclonal Antibody-Based Screening Assay for Factor Inhibiting Hypoxia-Inducible Factor Inhibitors
2008
Distinct aerobic and hypoxic mechanisms of HIF-α regulation by CSN5
2004
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
The good, the bad and the ugly in oxygen-sensing: ROS, cytochromes and prolyl-hydroxylases
2006
The Role of Hypoxia in Development of the Mammalian Embryo
2009
Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors
2004
Oxide Semiconductor Thin‐Film Transistors: A Review of Recent Advances
2012 Standout
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
Heart mitochondria: gates of life and death
2007
The Acetylase/Deacetylase Couple CREB-binding Protein/Sirtuin 1 Controls Hypoxia-inducible Factor 2 Signaling
2012
Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family
2002 StandoutNobel
Fine Tuning Our Cellular Factories: Sirtuins in Mitochondrial Biology
2011
SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization
2011
Macrophage Migration Inhibitory Factor Activates Hypoxia-Inducible Factor in a p53-Dependent Manner
2008 StandoutNobel
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells
2007 StandoutNobel
Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism☆
2009
Role of apoptosis in cardiovascular disease
2009
Chromatin as an oxygen sensor and active player in the hypoxia response
2011
Gene expression and hypoxia in breast cancer
2011
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Perspectives on Oxygen Sensing
1999 StandoutNobel
Role of Prolyl Hydroxylation in Oncogenically Stabilized Hypoxia-inducible Factor-1α
2002
The function of hypoxia‐inducible factor 1 (HIF‐1) is impaired in senescent mice
1999
Piezo2 senses airway stretch and mediates lung inflation-induced apnoea
2016 StandoutNatureNobel
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
Multiple Functions of Jab1 Are Required for Early Embryonic Development and Growth Potential in Mice
2004 StandoutNobel
The asparaginyl hydroxylase factor-inhibiting HIF is essential for tumor growth through suppression of the p53–p21 axis
2011
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
Evaluation of HIF-1 inhibitors as anticancer agents
2007 StandoutNobel
Oxygen homeostasis
2009 StandoutNobel
Effects of hypoxia and HIFs on cancer metabolism
2012
Models for oxygen sensing in yeast: implications for oxygen-regulated gene expression in higher eucaryotes
1999
The Role of Endogenous NADPH Oxidases in Airway and Pulmonary Vascular Smooth Muscle Function
2003
High-performance all-solid-state batteries enabled by salt bonding to perovskite in poly(ethylene oxide)
2019 StandoutNobel
Clues from cell metabolism
2010 StandoutNatureNobel
Review paper: Transparent amorphous oxide semiconductor thin film transistor
2011
A 3D Nanostructured Hydrogel‐Framework‐Derived High‐Performance Composite Polymer Lithium‐Ion Electrolyte
2018 StandoutNobel
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Oxygen sensing in yeast: Evidence for the involvement of the respiratory chain in regulating the transcription of a subset of hypoxic genes
1999
A Nontranscriptional Role for HIF-1α as a Direct Inhibitor of DNA Replication
2013 StandoutNobel
Highly Transparent and Conductive Al-Doped ZnO/Ag/Al-Doped ZnO Multilayer Source/Drain Electrodes for Transparent Oxide Thin Film Transistors
2011
Control of inositol 1,4,5-trisphosphate-induced Ca2+ release by cytosolic Ca2+
1995 Standout
Defective carotid body function and impaired ventilatory responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1α
2002 StandoutNobel
Role of components of the phagocytic NADPH oxidase in oxygen sensing
2002
Ionic Conductivity Enhancement of Polymer Electrolytes with Ceramic Nanowire Fillers
2015
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
2011 StandoutNobel
Oxygen Sensing and the Transcriptional Regulation of Oxygen-Responsive Genes in Yeast
1998
Hypoxia-Inducible Factor-1 Is Central to Cardioprotection
2008
Hypoxia-induced methylation of a pontin chromatin remodeling factor
2011
C5L2, a Nonsignaling C5A Binding Protein
2003
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
2006 StandoutNobel
Enhancing ionic conductivity in composite polymer electrolytes with well-aligned ceramic nanowires
2017
Effect of desferrioxamine and metals on the hydroxylases in the oxygen sensing pathway
2005
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
β-arrestin- but not G protein-mediated signaling by the “decoy” receptor CXCR7
2009 StandoutNobel
Cellular adaptation to hypoxia: O 2 ‐sensing protein hydroxylases, hypoxia‐inducible transcription factors, and O 2 ‐regulated gene expression
2002
Localization effect of a current-path in amorphous In–Ga–Zn–O thin film transistors with a highly doped buried-layer
2011
Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively
2018 StandoutNobel
PAS Domains: Internal Sensors of Oxygen, Redox Potential, and Light
1999
Kinase requirements in human cells: III. Altered kinase requirements inVHL−/− cancer cells detected in a pilot synthetic lethal screen
2008 StandoutNobel
Recent advances and contraversies on the role of pulmonary neuroepithelial bodies as airway sensors
2012
Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases
2014 Standout
Induction of tumor arrest and differentiation with prolonged survival by intermittent hypoxia in a mouse model of acute myeloid leukemia
2005
Inorganic and organic hybrid solid electrolytes for lithium-ion batteries
2016
Zinc concentration dependence study of solution processed amorphous indium gallium zinc oxide thin film transistors using high-k dielectric
2010
New composite polymer electrolyte comprising mesoporous lithium aluminate nanosheets and PEO/LiClO4
2007
SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production
2013
Angiogenesis Is Induced in a Rabbit Model of Hindlimb Ischemia by Naked DNA Encoding an HIF-1α/VP16 Hybrid Transcription Factor
2000
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Broad Oxygen Tolerance in the Nematode Caenorhabditis Elegans
2000
Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
2018 StandoutNobel
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia
2012
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
The COP9 Signalosome
2003
Subgap states, doping and defect formation energies in amorphous oxide semiconductor a‐InGaZnO4 studied by density functional theory
2010
Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1
2007 StandoutNobel
Flexible, Scalable, and Highly Conductive Garnet‐Polymer Solid Electrolyte Templated by Bacterial Cellulose
2018
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
Composite Polymer Electrolytes with Li7La3Zr2O12 Garnet-Type Nanowires as Ceramic Fillers: Mechanism of Conductivity Enhancement and Role of Doping and Morphology
2017
Mechanism of hypoxia-inducible factor 1α-mediated Mcl1 regulation in Helicobacter pylori-infected human gastric epithelium
2010
Two Transactivation Domains of Hypoxia-inducible Factor-1α Regulated by the MEK-1/p42/p44 MAPK Pathway
2002
Jun activation domain-binding protein 1 expression in breast cancer inversely correlates with the cell cycle inhibitor p27(Kip1).
2003
Works of Jong‐Wan Park being referenced
FIH Is an Oxygen Sensor in Ovarian Cancer for G9a/GLP-Driven Epigenetic Regulation of Metastasis-Related Genes
2017
A novel mode of action of YC-1 in HIF inhibition: stimulation of FIH-dependent p300 dissociation from HIF-1α
2008
Hypoxia-Inducible Factor-1α Obstructs a Wnt Signaling Pathway by Inhibiting the hARD1-Mediated Activation of β-Catenin
2008
Hypoxia-inducible Factor α Subunit Stabilization by NEDD8 Conjugation Is Reactive Oxygen Species-dependent
2010
HIF-2α Enhances β-Catenin/TCF-Driven Transcription by Interacting with β-Catenin
2010
Jab1 Interacts Directly with HIF-1α and Regulates Its Stability
2002
NOX4 as an oxygen sensor to regulate TASK-1 activity
2005
A dominant-negative isoform lacking exons 11 and 12 of the human hypoxia-inducible factor-1α gene
2002
Role of apoptosis-inducing factor in myocardial cell death by ischemia–reperfusion
2003
Jumonji histone demethylases as emerging therapeutic targets
2016
Versatile pharmacological actions of YC-1: anti-platelet to anticancer
2004
Inhibitory effect of YC-1 on the hypoxic induction of erythropoietin and vascular endothelial growth factor in Hep3B cells11Abbreviations: EPO, erythropoietin; VEGF, vascular endothelial growth factor; HIF, hypoxia-inducible factor; NO, nitric oxide; NOS, nitric oxide synthase; CO, carbon monoxide; sGC, soluble guanylate cyclase; cGMP, cyclic GMP; YC-1, 3-(5′-hydroxymethyl-2′-furyl)-1-benzylindazole; SNP, sodium nitroprusside; ODQ, 1H-(1,2,4)oxadiazole (4,3a)quinoxatin-1-one; MB, methylene blue; NAME, N(G)-nitro-L-arginine methyl ester; RT-PCR, reverse transcription polymerase chain reaction; and EMSA, electrophoretic mobility gel shift.
2001
Reactive oxygen species‐mediated cyclin D1 degradation mediates tumor growth retardation in hypoxia, independently of p21cip1 and hypoxia‐inducible factor
2008
HIF-1α controls keratinocyte proliferation by up-regulating p21(WAF1/Cip1)
2007
ATP6V0C Competes with Von Hippel-Lindau Protein in Hypoxia-Inducible Factor 1α (HIF-1α) Binding and Mediates HIF-1α Expression by Bafilomycin A1
2006
Curcumin Inhibits Hypoxia-Inducible Factor-1 by Degrading Aryl Hydrocarbon Receptor Nuclear Translocator: A Mechanism of Tumor Growth Inhibition
2006
Preclinical evaluation of YC-1, a HIF inhibitor, for the prevention of tumor spreading
2007
Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α
2010
Oxidative Dimerization of PHD2 is Responsible for its Inactivation and Contributes to Metabolic Reprogramming via HIF-1α Activation
2016
Amorphous Indium Gallium Zinc Oxide Semiconductor Thin Film Transistors Using O2 Plasma Treatment on the SiNx Gate Insulator
2010
Electrochemical characteristics of two types of PEO-based composite electrolyte with functional SiO2
2003
Gastric epithelial reactive oxygen species prevent normoxic degradation of hypoxia-inducible factor-1alpha in gastric cancer cells.
2003
A new HIF-1 alpha variant induced by zinc ion suppresses HIF-1-mediated hypoxic responses
2001
Copper source/drain electrode contact resistance effects in amorphous indium–gallium–zinc‐oxide thin film transistors
2009
Effects of Oxygen Partial Pressure on the Electrical Characteristics of InGaZnO Thin Film Transistors
2009
Erythropoietin: a Model System for Studying Oxygen-Dependent Gene Regulation
1998
Bortezomib inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated repression of hypoxia-inducible factor-1
2008
Amphotericin B blunts erythropoietin response to hypoxia by reinforcing FIH-mediated repression of HIF-1
2005
Early Expression of Myocardial HIF-1α in Response to Mechanical Stresses
2002
Hypoxia-Inducible Factor 1-Related Diseases and Prospective Therapeutic Tools
2004
Role of functional nano-sized inorganic fillers in poly(ethylene) oxide-based polymer electrolytes
2003
Hypoxic activation of the atrial natriuretic peptide gene promoter through direct and indirect actions of hypoxia-inducible factor-1
2003
Improvement in the bias stability of amorphous indium gallium zinc oxide thin-film transistors using an O2 plasma-treated insulator
2009
A domain responsible for HIF-1α degradation by YC-1, a novel anticancer agent
2006
An investigation of contact resistance between metal electrodes and amorphous gallium–indium–zinc oxide (a-GIZO) thin-film transistors
2010
STAT3 inhibits the degradation of HIF-1α by pVHL-mediated ubiquitination
2008