Citation Impact
Citing Papers
Positional Information and Pattern Formation
2016
Notch signalling controls pancreatic cell differentiation
1999 StandoutNatureNobel
Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo
1996
Conversion of Xenopus Ectoderm into Neurons by NeuroD, a Basic Helix-Loop-Helix Protein
1995 Science
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel
Mesodermal patterning by an inducer gradient depends on secondary cell–cell communication
1994
A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos
1992 Nature
A Robust and Highly Efficient Immune Cell Reprogramming System
2009
A community effect in animal development
1988 StandoutNatureNobel
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
2004 StandoutNature
Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing center
1991
Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo
1999
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
1997 StandoutNatureNobel
Gradual Refinement of Activin-Induced Thresholds Requires Protein Synthesis
2000
A maternal mRNA localized to the vegetal hemisphere in xenopus eggs codes for a growth factor related to TGF-β
1987
Extreme Makeover: Converting One Cell into Another
2008
Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo
1994
Expression of a xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction
1991
Eomesodermin, a Key Early Gene in Xenopus Mesoderm Differentiation
1996 StandoutNobel
The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo
1989 StandoutNatureNobel
Dorsoventral Patterning in Xenopus: Inhibition of Ventral Signals by Direct Binding of Chordin to BMP-4
1996 Standout
Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures
1990
Activin has direct long-range signalling activity and can form a concentration gradient by diffusion
1997 StandoutNobel
A Xenopus mRNA related to Drosophila twist is expressed in response to induction in the mesoderm and the neural crest
1989 StandoutNobel
Self-Renewal, Multipotency, and the Existence of Two Cell Populations within an Epithelial Stem Cell Niche
2004 Standout
Neural and developmental actions of lithium: A unifying hypothesis
1989 Standout
Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells
2001
The Interpretation of Position in a Morphogen Gradient as Revealed by Occupancy of Activin Receptors
1998 StandoutNobel
Forcing cells to change lineages
2009 Nature
Direct and Long-Range Action of a Wingless Morphogen Gradient
1996
Mix.1, a homeobox mRNA inducible by mesoderm inducers, is expressed mostly in the presumptive endodermal cells of Xenopus embryos
1989
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
1993 StandoutNobel
Protein kinase C mediates neural induction in Xenopus laevis
1988 Nature
Telomerase modulates Wnt signalling by association with target gene chromatin
2009 Nature
In vivo reprogramming of adult pancreatic exocrine cells to β-cells
2008 StandoutNature
Activin signalling and response to a morphogen gradient
1994 StandoutNatureNobel
Dorsalization of mesoderm induction by lithium
1989
Pattern specification in imaginal discs ofDrosophila melanogaster
1979
Gene expression in the embryonic Xenopus liver
2001
Synergistic induction of mesoderm by FGF and TGF-β and the identification of an mRNA coding for FGF in the early xenopus embryo
1987
FGF-2: Apical Ectodermal Ridge Growth Signal for Chick Limb Development
1994 Science
Organogenesis in C. elegans: Positioning of neurons and muscles in the egg-laying system
1990 StandoutNobel
Morphogen gradients
2000
Xsox17α and -β Mediate Endoderm Formation in Xenopus
1997
Lithium-induced teratogenesis in frog embryos prevented by a polyphosphoinositide cycle intermediate or a diacylglycerol analog
1989
Identification of a potent Xenopus mesoderm-inducing factor as a homologue of activin A
1990 Nature
The molecular genetics of embryonic pattern formation in Drosophila
1988 StandoutNature
Growth factors as morphogens: do gradients and thresholds establish body plan?
1991
Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox geneHox-#150;1.6
1992 StandoutNatureNobel
Effect of partial pancreatectomy on diabetic status in BALB/c mice
1999
The murine and Drosophila homeobox gene complexes have common features of organization and expression
1989
A common plan for dorsoventral patterning in Bilateria
1996 Nature
Multiple intercellular signalling systems control the development of the Caenorhabditis elegans vulva
1991 StandoutNatureNobel
Wingless Repression of Drosophila frizzled 2 Expression Shapes the Wingless Morphogen Gradient in the Wing
1998
Processed Vg1 protein is an axial mesoderm inducer in xenopus
1993
Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid
1991
An antisense mRNA directs the covalent modification of the transcript encoding fibroblast growth factor in Xenopus oocytes
1989
Retinoic acid causes an anteroposterior transformation in the developing central nervous system
1989 Nature
The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner
1988 StandoutNobel
The entire mesodermal mantle behaves as Spemann's organizer in dorsoanterior enhanced Xenopus laevis embryos
1988
Problems and paradigms: Morphogens and pattern formation
1997
Activin receptor mRNA is expressed early in Xenopus embryogenesis and the level of the expression affects the body axis formation
1991
Dynamic control of positional information in the early Drosophila embryo
2004 Nature
The Spemann Organizer Signal noggin Binds and Inactivates Bone Morphogenetic Protein 4
1996
Absence of radius and ulna in mice lacking hoxa-11 andhoxd-11
1995 StandoutNatureNobel
Determination of spatial domains of zygotic gene expression in the Drosophila embryo by the affinity of binding sites for the bicoid morphogen
1989 StandoutNatureNobel
Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes
1988 StandoutNatureNobel
T-box genes: what they do and how they do it
1999
Mouse gastrulation: the formation of a mammalian body plan
1997
Injected Wnt RNA induces a complete body axis in Xenopus embryos
1991
A synthetic multicellular system for programmed pattern formation
2005 StandoutNatureNobel
A gradient of bicoid protein in Drosophila embryos
1988 StandoutNobel
The dorsal protein is distributed in a gradient in early drosophila embryos
1988
Eomesodermin is required for mouse trophoblast development and mesoderm formation
2000 StandoutNatureNobel
Responses of embryonic xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm
1992
Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm
1993 Nature
A community effect in muscle development
1993 StandoutNobel
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
A conserved retinoic acid response element required for early expression of the homeobox gene Hoxb-1
1994 StandoutNatureNobel
Bone morphogenetic protein-4 (BMP-4) acts during gastrula stages to cause ventralization of Xenopus embryos
1996
Regulation of the fibroblast growth factor receptor in early Xenopus embryos.
1990
Muscle gene activation in Xenopus requires intercellular communication during gastrula as well as blastula stages
1992 StandoutNobel
Retinoic acid perturbs the expression of Xhox.lab genes and alters mesodermal determination in Xenopus laevis.
1991
DVR-4 (Bone Morphogenetic Protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction
1992
Slow emergence of a multithreshold response to activin requires cell-contact-dependent sharpening but not prepattern
1994
Fates and states of determination of single vegetal pole blastomeres of X. laevis
1984
Homeo Boxes in the Study of Development
1987 Science
Single-cell transplantation determines the time when Xenopus muscle precursor cells acquire a capacity for autonomous differentiation.
1993 StandoutNobel
A mesoderm-inducing factor is produced by aXenopuscell line
1987
Cell type-specific activation of actin genes in the early amphibian embryo
1984 StandoutNatureNobel
Crystal Structure of a Group I Ribozyme Domain: Principles of RNA Packing
1996 StandoutScienceNobel
Altering the Genome by Homologous Recombination
1989 StandoutScienceNobel
Mesoderm Induction in Amphibians: the Role of TGF-β2-Like Factors
1988 Science
Slow emergence of a multithreshold response to activin requires cell-contact-dependent sharpening but not prepattern
1994
Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-II
1990 StandoutNatureNobel
The restrictive effect of early exposure to lithium upon body pattern in Xenopus development, studied by quantitative anatomy and immunofluorescence
1988
Fate map for the 32-cell stage ofXenopus laevis
1987
Bix1, a direct target of Xenopus T-box genes, causes formation of ventral mesoderm and endoderm
1998
Positional information revisited
1989
Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouse.
1988
A homeobox-containing marker of posterior neural differentiation shows the importance of predetermination in neural induction
1987 StandoutNobel
Molecular mechanisms of Spemann's organizer formation: conserved growth factor synergy between Xenopus and mouse.
1995
Requirement of FGF-4 for Postimplantation Mouse Development
1995 Science
The transforming growth factor beta family and induction of the vertebrate mesoderm: bone morphogenetic proteins are ventral inducers.
1994
Identification of a retinoic acid-sensitive period during primary axis formation in Xenopus laevis.
1990
Diversity of expression of non-muscle actin in amphibia
1981
Nuclear reprogramming and stem cell creation
2003 StandoutNobel
Bimodal and graded expression of theXenopushomeobox geneXhox3during embryonic development
1989
Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects.
1995
Multipotential Nestin-Positive Stem Cells Isolated From Adult Pancreatic Islets Differentiate Ex Vivo Into Pancreatic Endocrine, Exocrine, and Hepatic Phenotypes
2001
Vegetal pole cells and commitment to form endoderm in Xenopus laevis
1987
Biochemical specificity of Xenopus notochord
1985
Inductive effects of fibroblast growth factor and lithium ion on Xenopus blastula ectoderm
1988
The localization of an inductive response
1989 StandoutNobel
Demonstration of Two Different Processes of β-Cell Regeneration in a New Diabetic Mouse Model Induced by Selective Perfusion of Alloxan
1997
Functional gap junctions are not required for muscle gene activation by induction in Xenopus embryos.
1987 StandoutNobel
The origin of the mesoderm in an anuran, Xenopus laevis, and a urodele, Ambystoma mexicanum
1983
Loss of competence in amphibian induction can take place in single nondividing cells.
1989 StandoutNobel
Endogenous patterns of TGFβ superfamily signaling during early Xenopus development
2000
An indelible lineage marker for Xenopus using a mutated green fluorescent protein
1996 StandoutNobel
Potentiation by the lithium ion of morphogenetic responses to a Xenopus inducing factor
1989
Mesodermal Patterning by a Gradient of the Vertebrate Homeobox Gene goosecoid
1994 Science
Secretion and mesoderm-inducing activity of the TGF-beta-related domain of Xenopus Vg1.
1993
On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo.
1994
The ALK-2 and ALK-4 activin receptors transduce distinct mesoderm-inducing signals during early Xenopus development but do not co-operate to establish thresholds
1997
Drosophila short gastrulation induces an ectopic axis in Xenopus: evidence for conserved mechanisms of dorsal-ventral patterning
1995
Intercellular signaling and gene regulation during early embryogenesis of Xenopus laevis.
1994
Mesoderm induction and mesoderm-inducing factors in early amphibian development
1989
Single cells can sense their position in a morphogen gradient
1999 StandoutNobel
The appearance and distribution of intermediate filament proteins during differentiation of the central nervous system, skin and notochord of Xenopus laevis
1986
A genetic pathway for the specification of the vulval cell lineages of Caenorhabditis elegans
1987 StandoutNatureNobel
Bix4is activated directly by VegT and mediates endoderm formation inXenopusdevelopment
1999
Chimeric analysis of fibroblast growth factor receptor-1 (Fgfr1) function: a role for FGFR1 in morphogenetic movement through the primitive streak
1997
A role for cytoplasmic determinants in mesoderm patterning: cell-autonomous activation of the goosecoid and Xwnt-8 genes along the dorsoventral axis of early Xenopus embryos
1994 StandoutNobel
Presence of activin (erythroid differentiation factor) in unfertilized eggs and blastulae of Xenopus laevis.
1991
Retinoic acid modifies mesodermal patterning in early Xenopus embryos.
1991
Embryonic induction - molecular prospects
1987 StandoutNobel
Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development
1998
Competition between noggin and bone morphogenetic protein 4 activities may regulate dorsalization during Xenopus development.
1995
Development of the ectoderm in Xenopus: Tissue specification and the role of cell association and division
1986
Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern
1995
Pattern formation during vulval development in C. elegans
1986 StandoutNobel
Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development
1992
The Xenopus MyoD gene: an unlocalised maternal mRNA predates lineage- restricted expression in the early embryo
1990
Activin-mediated mesoderm induction requires FGF
1994
The role of fibroblast growth factor in early Xenopus development
1989
Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion
2000 StandoutScienceNobel
Promotion of Trophoblast Stem Cell Proliferation by FGF4
1998 Science
The development of animal cap cells in Xenopus: a measure of the start of animal cap competence to form mesoderm
1987
A quantitative analysis of the effect of all-trans-retinoic acid on the pattern of chick wing development
1985
Expression ofXenopusN-CAM RNA in ectoderm is an early response to neural induction
1987
Diversity and Pattern in the Developing Spinal Cord
1996 Science
Xenopus endo B is a keratin preferentially expressed in the embryonic notochord.
1988
RNA structure
1977
The Presence of Fibroblast Growth Factor in the Frog Egg: Its Role as a Natural Mesoderm Inducer
1988 Science
Mesoderm-inducing factors in early vertebrate development.
1993
From intestine to muscle: Nuclear reprogramming through defective cloned embryos
2002 StandoutNobel
Morphogen gradient interpretation
2001 StandoutNatureNobel
A type 1 serine/threonine kinase receptor that can dorsalize mesoderm in Xenopus.
1995 StandoutNobel
Mutations affecting segment number and polarity in Drosophila
1980 StandoutNatureNobel
Works of Jonathan Slack being referenced
eFGF is expressed in the dorsal midline of Xenopus laevis
1995
Development of the gut inXenopus laevis
1998
Molecular and Cellular Basis of Regeneration and Tissue Repair
2007
Metaplasia and transdifferentiation: from pure biology to the clinic
2007
Embryonic induction
1993
Inducing factors in Xenopus early embryos
1994
Regional gene expression in the epithelia of the Xenopus tadpole gut
2000
Molecular basis of transdifferentiation of pancreas to liver
2000
Experimental Conversion of Liver to Pancreas
2003
Two phases of Hox gene regulation during early Xenopus development
1998
The Einsteck-Method: Position and Structure of Projections Formed by Implants of a Ventral Character
1994
Transdifferentiation of pancreas to liver
2002
The zootype and the phylotypic stage
1993 Nature
Analysis of embryonic induction by using cell lineage markers
1984
Dorsalization and neural induction: properties of the organizer in Xenopus laevis.
1983
eFGF, Xcad3 and Hox genes form a molecular pathway that establishes the anteroposterior axis in Xenopus
1996
In vitro development of isolated ectoderm from axolotl gastrulae
1984
Determination and cellular commitment in the embryonic amphibian mesoderm
1980 Nature
Normal fates and states of specification of different regions in the axolotl gastrula
1985
Developmental biology of the pancreas
1995
Properties of the dorsalizing signal in gastrulae of Xenopus laevis
1993
Homoeotic transformations in man: Implications for the mechanism of embryonic development and for the organization of epithelia
1985
Mesoderm induction in early Xenopus embryos by heparin-binding growth factors
1987 Nature
Single cell analysis of mesoderm formation in the Xenopus embryo
1991
Presence of basic fibroblast growth factor in the early Xenopus embryo
1989
Analysis of competence: receptors for fibroblast growth factor in early Xenopus embryos
1989
Expression of a novel FGF in theXenopusembryo. A new candidate inducing factor for mesoderm formation and anteroposterior specification
1992
A mesoderm-inducing factor produced by WEHI-3 murine myelomonocytic leukemia cells is activin A
1990
The nature of the mesoderm-inducing signal in Xenopus: a transfilter induction study
1991
Thresholds in development
1977
Morphogenetic gradients — past and present
1987
Cell commitment and gene expression in the axolotl embryo
1980
eFGF regulates Xbra expression during Xenopus gastrulation.
1994
The role of fibroblast growth factors in early Xenopus development.
1996
Regional biosynthetic markers in the early amphibian embryo
1984
Developmental biology: A Rosetta stone for pattern formation in animals?
1984 Nature
Cell lineage labels and region-specific markers in the analysis of inductive interactions
1985
Structural-proliferative units and organ growth: effects of insulin-like growth factor 2 on the growth of colon and skin
2003
An interaction between dorsal and ventral regions of the marginal zone in early amphibian embryos
1980
Mesoderm induction in Xenopus laevis: a quantitative study using a cell lineage label and tissue-specific antibodies
1985
Mesoderm-inducing factors: a small class of molecules
1988
Mesoderm-inducing properties of INT-2 and kFGF: two oncogene-encoded growth factors related to FGF
1989
Cell lineage labels in the early amphibian embryo
1984
Multiple conformations of ribosomal precursor RNA
1975 Nature
Molecule of the moment
1991 Nature
Peanut lectin receptors in the early amphibian embryo: Regional markers for the study of embryonic induction
1985
Developmental biology
1987
Control of anteroposterior pattern in the axolotl forelimb by a smoothly graded signal
1977
Stem Cells in Epithelial Tissues
2000 Science
Mechanism of anteroposterior axis specification in vertebrates Lessons from the amphibians
1992
Regional specification within the mesoderm of early embryos ofXenopus laevis
1987
Developmental expression of the Xenopus int-2 (FGF-3) gene: activation by mesodermal and neural induction
1992
Spatial response to fibroblast growth factor signalling inXenopusembryos
1999