Citation Impact
Citing Papers
Antibiotics induce redox-related physiological alterations as part of their lethality
2014
Rhizobium induces DNA damage in Caenorhabditis elegans intestinal cells
2019 StandoutNobel
Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica
2008 StandoutScience
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Role of the CXCR4/SDF-1 chemokine axis in circulating neutrophil homeostasis
2004
TOR Signaling in Growth and Metabolism
2006 Standout
Hypoxia-inducible factor-1α contributes to the profibrotic action of angiotensin II in renal medullary interstitial cells
2010
Effects of sirolimus on plasma lipids, lipoprotein levels, and fatty acid metabolism in renal transplant patients
2002
β-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation
2009 StandoutNobel
A role for CD95 ligand in preventing graft rejection
1995 StandoutNature
Th2 cells and GATA-3 in asthma: new insights into the regulation of airway inflammation
1999
Rac1 Activity Is Required for the Activation of Hypoxia-inducible Factor 1
2001 StandoutNobel
mTOR Signaling in Growth Control and Disease
2012 Standout
Arrestin Regulates MAPK Activation and Prevents NADPH Oxidase-dependent Death of Cells Expressing CXCR2
2004
Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death
1996 Standout
The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity
2000
Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion
2005 Standout
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
2002 StandoutNature
Apoptosis by Death Factor
1997 Standout
Rapamycin, an mTOR inhibitor, disrupts triglyceride metabolism in guinea pigs
2006
Development of Lupus-like Autoimmune Diseases by Disruption of the PD-1 Gene Encoding an ITIM Motif-Carrying Immunoreceptor
1999 StandoutNobel
Development of Novel Fluorescence Probes That Can Reliably Detect Reactive Oxygen Species and Distinguish Specific Species
2003
Multiple roles of oxidants in the pathogenesis of asbestos-induced diseases
2003
Nonresolving Inflammation
2010 Standout
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis
2001
FasGene Mutations in the Canale–Smith Syndrome, an Inherited Lymphoproliferative Disorder Associated with Autoimmunity
1996
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function
2006 StandoutNature
Involvement of MACH, a Novel MORT1/FADD-Interacting Protease, in Fas/APO-1- and TNF Receptor–Induced Cell Death
1996 Standout
The development of allergic inflammation
2008 StandoutNature
Apoptosis
2002 Standout
Fluorescent Probes for Hydrogen Peroxide Based on a Non‐Oxidative Mechanism
2004
Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus
1998
The molecular basis for apoptotic defects in patients with CD95 (Fas/Apo-1) mutations
1999
Induction of interleukin-8 preserves the angiogenic response in HIF-1α–deficient colon cancer cells
2005
Rac1 Regulates Stress-induced, Redox-dependent Heat Shock Factor Activation
2000
Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis
2004 Standout
Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret
1994 StandoutNature
Understanding cellular networks to improve hematopoietic stem cell expansion cultures
2006
FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex
1996 Standout
Human Mast Cell Transcriptome Project
2001
The Fas Death Factor
1995 StandoutScience
Origin and physiological roles of inflammation
2008 StandoutNature
A Stable Nonfluorescent Derivative of Resorufin for the Fluorometric Determination of Trace Hydrogen Peroxide: Applications in Detecting the Activity of Phagocyte NADPH Oxidase and Other Oxidases
1997
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
1998 StandoutNature
AKT/PKB Signaling: Navigating the Network
2017 Standout
The Primary Immunodeficiencies
1995
Points of control in inflammation
2002 StandoutNature
Phosphorylation of H2AX at Short Telomeres in T Cells and Fibroblasts
2004 StandoutNobel
The TNF and TNF Receptor Superfamilies
2001 Standout
Dominant interfering fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome
1995
Cancer-related inflammation
2008 StandoutNature
Inhibition of death receptor signals by cellular FLIP
1997 StandoutNature
Autoimmune Lymphoproliferative Syndrome with Defective Fas: Genotype Influences Penetrance
1999
A Common Mechanism of Cellular Death Induced by Bactericidal Antibiotics
2007 Standout
Antibacterial drug discovery in the resistance era
2016 StandoutNature
β-Arrestin-2 regulates the development of allergic asthma
2003 StandoutNobel
Optical probes for detection and quantification of neutrophils’ oxidative burst. A review
2009
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice
2002 StandoutNobel
Oxidative Stress Enzymes Are Required for DAF-16-Mediated Immunity Due to Generation of Reactive Oxygen Species byCaenorhabditis elegans
2007
CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells.
1996 StandoutNobel
Proteasome regulation of activation-induced T cell death
1997 StandoutNobel
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
Familial Nature of Congenital Absence and Severe Dysgenesis of Both Kidneys
1984
Ce-Duox1/BLI-3 Generates Reactive Oxygen Species as a Protective Innate Immune Mechanism in Caenorhabditis elegans
2009
The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types
2002 StandoutNobel
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations
2000 StandoutScienceNobel
Regulation of Peroxisome Proliferator–Activated Receptor-γ Activity by Mammalian Target of Rapamycin and Amino Acids in Adipogenesis
2004
The Yin and Yang of T Cell Costimulation
1995 StandoutScienceNobel
The Duration of Nuclear Residence of NFAT Determines the Pattern of Cytokine Expression in Human SCID T Cells
2000
Renal agenesis in British Columbia
1985
β-Arrestin-2 regulates the development of allergic asthma
2003 StandoutNobel
MATURE T LYMPHOCYTE APOPTOSIS—Immune Regulation in a Dynamic and Unpredictable Antigenic Environment
1999
Systemic autoimmune disease as a consequence of defective lymphocyte death
1997
The Receptor for the Cytotoxic Ligand TRAIL
1997 StandoutScience
Defective CD95/APO-1/Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type Ia
1999
Inhibition of the Rac1 GTPase protects against nonlethal ischemia/reperfusion‐induced necrosis and apoptosis in vivo
2000
Growth Factors, Matrices, and Forces Combine and Control Stem Cells
2009 StandoutScience
Generation and Detection of Reactive Oxygen Species in Photocatalysis
2017 Standout
Immunological Memory and Protective Immunity: Understanding Their Relation
1996 StandoutScience
An Inherited Disorder of Lymphocyte Apoptosis: The Autoimmune Lymphoproliferative Syndrome
1999
Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site
2023 StandoutNobel
Mechanisms and Genes of Cellular Suicide
1995 StandoutScience
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
Works of Jonathan S. Jaffe being referenced
CYTOKINE mRNA EXPRESSION IN HUMAN PLATELETS AND A MEGAKARYOCYTIC CELL LINE AND CYTOKINE MODULATION OF PLATELET FUNCTION
1997
Reduced interleukin-2 (IL-2) production in common variable immunodeficiency is due to a primary abnormality of CD4+ T cell differentiation
1993
Hydrogen peroxide release from human eosinophils on fibronectin: scopoletin enhances eosinophil activation
2000
Human lung mast cell IL-5 gene and protein expression: temporal analysis of upregulation following IgE-mediated activation.
1995
A highly sensitive fluorescent micro-assay of H2O2 release from activated human leukocytes using a dihydroxyphenoxazine derivative
1997
EFFECT OF SIROLIMUS ON THE METABOLISM OF ApoB100- CONTAINING LIPOPROTEINS IN RENAL TRANSPLANT PATIENTS1
2001
A novel lymphoproliferative/autoimmune syndrome resembling murine lpr/gld disease.
1992
FamiliaI aggregation in bilateral renal agenesis
1974
Abnormal cytokine expression in Sézary and adult T-cell leukemia cells correlates with the functional diversity between these T-cell malignancies.
1994