Citation Impact
Citing Papers
Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes
2003 StandoutScience
Missense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancer
2002
Clonal Integration of a Polyomavirus in Human Merkel Cell Carcinoma
2008 StandoutScience
Loss of ATM accelerates pancreatic cancer formation and epithelial–mesenchymal transition
2015
An Integrated Approach for Analysis of the DNA Damage Response in Mammalian Cells
2015 StandoutNobel
The DNA-damage response in human biology and disease
2009 StandoutNature
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
2006 StandoutNature
Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress
2010 StandoutNobel
Selective inhibition of the DNA-dependent protein kinase (DNA-PK) by the radiosensitizing agent caffeine
2004
Radiation-induced Assembly of Rad51 and Rad52 Recombination Complex Requires ATM and c-Abl
1999 Nobel
Cell-cycle checkpoints and cancer
2004 StandoutNature
mTOR Interacts with Raptor to Form a Nutrient-Sensitive Complex that Signals to the Cell Growth Machinery
2002 Standout
The DNA Damage Response Kinases DNA-dependent Protein Kinase (DNA-PK) and Ataxia Telangiectasia Mutated (ATM) Are Stimulated by Bulky Adduct-containing DNA
2011 StandoutNobel
Proliferation and hypoxia in human squamous cell carcinoma of the cervix: First report of combined immunohistochemical assays
1997
Electron microscopy and 3D reconstructions reveal that human ATM kinase uses an arm-like domain to clamp around double-stranded DNA
2003
Cell Cycle-Dependent Expression of Phosphorylated Histone H2AX: Reduced Expression in Unirradiated but not X-Irradiated G1-Phase Cells
2003
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
2005 StandoutNature
Genetic instabilities in human cancers
1998 StandoutNature
ATM: from gene to function
1998
TOR, a Central Controller of Cell Growth
2000 Standout
ATM and related protein kinases: safeguarding genome integrity
2003 Standout
Breast and Ovarian Cancer
2003
Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy
2005 StandoutNature
Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress
2000
Gene-expression profiling reveals distinct expression patterns for Classic versus Variant Merkel cell phenotypes and new classifier genes to distinguish Merkel cell from small-cell lung carcinoma
2004
Cancer Risk and the ATM Gene: a Continuing Debate
2000
ATM associates with and phosphorylates p53: mapping the region of interaction
1998
Angiogenesis in cancer and other diseases
2000 StandoutNature
Differentiation state of skin fibroblast cultures versus risk of subcutaneous fibrosis after radiotherapy
1998
Molecular markers predicting radiotherapy response: Report and recommendations from an International Atomic Energy Agency technical meeting
2005
A DNA damage checkpoint response in telomere-initiated senescence
2003 StandoutNature
Immunogenicity of induced pluripotent stem cells
2011 StandoutNature
Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology
2006 Standout
Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm
2000 StandoutNobel
The Inherited Basis of Human Radiosensitivity
2001
UV-induced Ataxia-telangiectasia-mutated and Rad3-related (ATR) Activation Requires Replication Stress
2004
ATM, ATR and DNA-PK: initiators of the cellular genotoxic stress responses
2003
Hypoxia Inhibits G1/S Transition through Regulation of p27 Expression
2001 StandoutNobel
Abnormal regulation of DDB2 gene expression in xeroderma pigmentosum group E strains
2001
ATM: Genome stability, neuronal development, and cancer cross paths
2001
Hypothesis: Ataxia‐telangiectasia: Is ATM a sensor of oxidative damage and stress?
1997
Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation
2004
Chk2 Oligomerization Studied by Phosphopeptide Ligation
2008 StandoutNobel
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
EMT: 2016
2016 Standout
Nuclear Retention of ATM at Sites of DNA Double Strand Breaks
2001
Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM
2016
Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Defined in Vitro System
2014 StandoutNobel
Cdc7-Dbf4 and the Human S Checkpoint Response to UVC
2007 StandoutNobel
Activation and regulation of ATM kinase activity in response to DNA double-strand breaks
2007
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
Can risk of radiotherapy-induced normal tissue complications be predicted from genetic profiles?
2005
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
2003 StandoutNature
Involvement of novel autophosphorylation sites in ATM activation
2006
Substrate Specificities and Identification of Putative Substrates of ATM Kinase Family Members
1999
Mechanisms of switching on p53: a role for covalent modification?
1999
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
2005 StandoutNature
Utilization of Oriented Peptide Libraries to Identify Substrate Motifs Selected by ATM
2000
Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers
2009 Standout
ATM-dependent phosphorylation of nibrin in response to radiation exposure
2000
Quantitative angiogenesis assays: Progress and problems
1997
Does variability in normal tissue reactions after radiotherapy have a genetic basis – where and how to look for it?
2002
The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator
2012 StandoutNobel
hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase
2001 Standout
HRad17 Colocalizes with NHP2L1 in the Nucleolus and Redistributes after UV Irradiation
1999
Cancer Risk in ATM Heterozygotes: A Model of Phenotypic and Mechanistic Differences between Missense and Truncating Mutations
1999
Interaction between ATM protein and c-Abl in response to DNA damage
1997 Nature
DNA Repair Synthesis and Ligation Affect the Processing of Excised Oligonucleotides Generated by Human Nucleotide Excision Repair
2014 StandoutNobel
Atm knock-in mice harboring an in-frame deletion corresponding to the human ATM 7636del9 common mutation exhibit a variant phenotype.
2001
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Direct Activation of the ATM Protein Kinase by the Mre11/Rad50/Nbs1 Complex
2004 Science
Purification and characterization of human DNA damage checkpoint Rad complexes
2001 StandoutNobel
Determination of Substrate Motifs for Human Chk1 and hCds1/Chk2 by the Oriented Peptide Library Approach
2002
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA
2007 StandoutNobel
Interaction of RAFT1 with Gephyrin Required for Rapamycin-Sensitive Signaling
1999 Science
CHK1 and CHK2 are differentially involved in mismatch repair–mediated 6-thioguanine-induced cell cycle checkpoint responses
2004
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres
2006 StandoutNobel
Spectrum of ATM gene mutations in a hospital-based series of unselected breast cancer patients.
2001
Asymmetric Catalysis by Architectural and Functional Molecular Engineering: Practical Chemo- and Stereoselective Hydrogenation of Ketones
2001 StandoutNobel
Hypoxia Links ATR and p53 through Replication Arrest
2002
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Phosphorylation of Serine 18 Regulates Distinct p53 Functions in Mice
2004
Autophosphorylation at serine 1981 stabilizes ATM at DNA damage sites
2009
Biological Action of Leptin as an Angiogenic Factor
1998 StandoutScience
Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53
1998 StandoutScience
In Vitro Analysis of the Role of Replication Protein A (RPA) and RPA Phosphorylation in ATR-mediated Checkpoint Signaling
2012 StandoutNobel
Association between Polymorphisms in the DNA Repair Genes, XRCC1, APE1, and XPD and Acute Side Effects of Radiotherapy in Breast Cancer Patients
2005
ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage
2007 StandoutScience
Surfing the p53 network
2000 StandoutNature
Structure, Recognition, and Processing of Cisplatin−DNA Adducts
1999 Standout
Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM
1999
Simultaneous precise editing of multiple genes in human cells
2019 StandoutNobel
DNA Double-Strand Breaks
2002 StandoutNobel
Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage
1998 StandoutScience
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
Posttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5
2006 StandoutNobel
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
ATAXIA-TELANGIECTASIA AND THE NIJMEGEN BREAKAGE SYNDROME: Related Disorders But Genes Apart
1997
Works of Jonathan Ramsay being referenced
Normal tissue radiosensitivity in breast cancer patients
1995
Intrinsic radiation sensitivity may not be the major determinant of the poor clinical outcome of glioblastoma multiforme
1993
Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms
1997
Mice heterozygous for mutation in Atm, the gene involved in ataxia-telangiectasia, have heightened susceptibility to cancer
2002
Radiation sensitivity of merkel cell carcinoma cell lines
1995
Radiosensitive melanoma cell line with mutation of the gene for ataxia telangiectasia
1998
Testing for mutations of the ataxia telangiectasia gene in radiosensitive breast cancer patients
1998
Mutation analysis of BRCA1 and BRCA2 cancer predisposition genes in radiation hypersensitive cancer patients
2000
ATP Activates Ataxia-Telangiectasia Mutated (ATM) in Vitro
2003
Quantitative studies on the transplantability of murine and human tumors into the brain and subcutaneous tissues of NCr/Sed nude mice.
1988