Standout Papers
Citation Impact
Citing Papers
Loss of conformational entropy in protein folding calculated using realistic ensembles and its implications for NMR-based calculations
2014 StandoutNobel
Structure of a Synaptic γδ Resolvase Tetramer Covalently Linked to Two Cleaved DNAs
2005 StandoutScienceNobel
Origins of Specificity in Protein-DNA Recognition
2010
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
De novo design of self-assembling helical protein filaments
2018 StandoutScienceNobel
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides
2007
The Structural Basis for mRNA Recognition and Cleavage by the Ribosome-Dependent Endonuclease RelE
2009 StandoutNobel
The role of dynamic conformational ensembles in biomolecular recognition
2009 Standout
Chiral Silver Phosphate Catalyzed Transformation of ortho‐Alkynylaryl Ketones into 1H‐Isochromene Derivatives through an Intramolecular‐Cyclization/Enantioselective‐Reduction Sequence
2013
Restricted and Regulated Overexpression Reveals Calcineurin as a Key Component in the Transition from Short-Term to Long-Term Memory
1998 StandoutNobel
Crystal structure of the site-specific recombinase γδ resolvase complexed with a 34 by cleavage site
1995 StandoutNobel
Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2
1996 StandoutNatureNobel
The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
2011 Standout
Dearomatization Strategies in the Synthesis of Complex Natural Products
2011
Biosynthesis of polyketide synthase extender units
2008
The ubiquitin-proteasome proteolytic pathway
1994 StandoutNobel
Wnt Signaling and an APC-Related Gene Specify Endoderm in Early C. elegans Embryos
1997 StandoutNobel
Catalytic Asymmetric Conjugate Addition/Oxidative Dearomatization Towards Multifunctional Spirocyclic Compounds
2011 StandoutNobel
Why are ?natively unfolded? proteins unstructured under physiologic conditions?
2000 Standout
Prediction of disordered regions in proteins from position specific score matrices
2003
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
2002 StandoutNature
Molecular Insights into the Biosynthesis of Guadinomine: A Type III Secretion System Inhibitor
2012 StandoutNobel
Rationalization of the effects of mutations on peptide andprotein aggregation rates
2003 Nature
MEX-3 Is a KH Domain Protein That Regulates Blastomere Identity in Early C. elegans Embryos
1996 StandoutNobel
Amyloid fibrillogenesis: themes and variations
2000
NMR studies in aqueous solution fail to identify significant conformational differences between the monomeric forms of two Alzheimer peptides with widely different plaque‐competence, Aβ(1–40)ox and Aβ(1–42)ox
2001 StandoutNobel
Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm
1999 Standout
DNA-induced increase in the .alpha.-helical content of C/EBP and GCN4
1991
Crystal structure of the Hhal DNA methyltransferase complexed with S-adenosyl-l-methionine
1993 StandoutNobel
Protein folding and misfolding
2003 StandoutNature
Prediction of “Aggregation-prone” and “Aggregation-susceptible” Regions in Proteins Associated with Neurodegenerative Diseases
2005
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Peptide‐Based Inhibitors of Amyloid Assembly
2006
Temperature dependence of intramolecular dynamics of the basic leucine zipper of GCN4: implications for the entropy of association with DNA
1999
Prediction and Functional Analysis of Native Disorder in Proteins from the Three Kingdoms of Life
2004 Standout
Solution Structure of the Core NFATC1/DNA Complex
1998
Catalytic Asymmetric Dearomatization Reactions
2012
A structural taxonomy of DNA-binding domains
1991 Nature
Protein structure prediction and analysis using the Robetta server
2004 StandoutNobel
Crystal structure of archaeal toxin-antitoxin RelE–RelB complex with implications for toxin activity and antitoxin effects
2005
High-resolution structure of an archaeal zinc ribbon defines a general architectural motif in eukaryotic RNA polymerases
1998
Alzheimer’s amyloid fibrils: structure and assembly
2000
cAMP-Dependent Regulation of Gene Transcription by cAMP Response Element-Binding Protein and cAMP Response Element Modulator
1995
Complilation and characteristics of dedicated transcription factors in Saccharomyces cerevisiae
1995
The pie-1 and mex-1 genes and maternal control of blastomere identity in early C. elegans embryos
1992 StandoutNobel
A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II
1994 StandoutNobel
CREB1 Encodes a Nuclear Activator, a Repressor, and a Cytoplasmic Modulator that Form a Regulatory Unit Critical for Long-Term Facilitation
1998 StandoutNobel
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
Costabilization of Peptide and RNA Structure in an HIV Rev Peptide-RRE Complex
1994
Metal-catalysed approaches to amide bond formation
2011 Standout
Computational design of ligand-binding proteins with high affinity and selectivity
2013 StandoutNatureNobel
skn-1, a maternally expressed gene required to specify the fate of ventral blastomeres in the early C. elegans embryo
1992
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
Transcriptional regulation by CREB and its relatives
1993
The maternal gene skn-1 encodes a protein that is distributed unequally in early C. elegans embryos
1993 StandoutNobel
Catalytic Asymmetric Dearomatizing Redox Cross Coupling of Ketones with Aryl Hydrazines Giving 1,4-Diketones
2015 StandoutNobel
Coupling of Local Folding to Site-Specific Binding of Proteins to DNA
1994 Science
Reversible Photocontrol of DNA Binding by a Designed GCN4-bZIP Protein
2006
Ultrafast Hydration Dynamics in Melittin Folding and Aggregation: Helix Formation and Tetramer Self-Assembly
2005
Stabilization of Coiled-Coil Peptide Domains by Introduction of Trifluoroleucine
2001
MULTIPROTEIN-DNA COMPLEXES IN TRANSCRIPTIONAL REGULATION
1999
Molecular basis for amyloid fibril formation and stability
2005
Ultrafast solvation dynamics at binding and active sites of photolyases
2010 StandoutNobel
Life with 6000 Genes
1996 StandoutScience
Structural and functional analysis of the NF-kappa B p65 C terminus. An acidic and modular transactivation domain with the potential to adopt an alpha-helical conformation.
1994
Asymmetric Syntheses of (−)-Mitorubrin and Related Azaphilone Natural Products
2006
Synthesis of the Azaphilones (+)-Sclerotiorin and (+)-8-O-Methylsclerotiorinamine Utilizing (+)-Sparteine Surrogates in Copper-Mediated Oxidative Dearomatization
2011
Highly conserved residues in the bZIP domain of yeast GCN4 are not essential for DNA binding.
1991
Unfolded proteins, compact states and molten globules
1992
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Purification and characterization of the carboxyl-terminal transactivation domain of Vmw65 from herpes simplex virus type 1.
1992
Aerobic Copper-Catalyzed Organic Reactions
2013 Standout
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Designed amyloid fibers as materials for selective carbon dioxide capture
2013 StandoutNobel
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Catalytic Asymmetric Epoxidation of α-Branched Enals
2010 StandoutNobel
Targeted Degradation of c-Fos, But Not v-Fos, by a Phosphorylation-Dependent Signal on c-Jun
1992 Science
Architecture of RNA Polymerase II and Implications for the Transcription Mechanism
2000 StandoutScienceNobel
Asymmetric Catalysis via Cyclic, Aliphatic Oxocarbenium Ions
2017 StandoutNobel
Enantioselective Synthesis of Bicyclo[2.2.2]octenones Using a Copper-Mediated Oxidative Dearomatization/[4 + 2] Dimerization Cascade
2008
The 3D profile method for identifying fibril-forming segments of proteins
2006 StandoutNobel
Implications of structures of synaptic tetramers of γδ resolvase for the mechanism of recombination
2006 StandoutNobel
4,4′-Dianilino-1,1′-binaphthyl-5,5′-disulfonate: report on non-β-sheet conformers of Alzheimer's peptide β(1–40)
2002
A structural census of the current population of protein sequences
1997 StandoutNobel
Nucleophilic Carbene and HOAt Relay Catalysis in an Amide Bond Coupling: An Orthogonal Peptide Bond Forming Reaction
2007
Common Structure of Soluble Amyloid Oligomers Implies Common Mechanism of Pathogenesis
2003 StandoutScience
Iron-Catalyzed Dioxygen-Driven C–C Bond Formation: Oxidative Dearomatization of 2-Naphthols with Construction of a Chiral Quaternary Stereocenter
2012
Ribosomal Synthesis of Unnatural Peptides
2005 StandoutNobel
Preferential binding of ATR protein to UV-damaged DNA
2002 StandoutNobel
Formation of a Monomeric DNA Binding Domain by Skn-1 bZIP and Homeodomain Elements
1994 Science
Chiral Anion Phase-Transfer Catalysis Applied to the Direct Enantioselective Fluorinative Dearomatization of Phenols
2013
Clustering of low-energy conformations near the native structures of small proteins
1998 StandoutNobel
The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted α Helices: Crystal structure of the protein-DNA complex
1992
Works of Jonathan P. Lee being referenced
Aromatic-aromatic interactions in the zinc finger motif
1992
Residual structure in the Alzheimer's disease peptide: probing the origin of a central hydrophobic cluster
1998
Simulation Study of the Structure and Dynamics of the Alzheimer’s Amyloid Peptide Congener in Solution
2001
Folding transition in the DMA-binding domain of GCN4 on specific binding to DNA
1990 Nature
Catalytic Ester−Amide Exchange Using Group (IV) Metal Alkoxide−Activator Complexes
2005
Synthesis of the Azaphilones Using Copper-Mediated Enantioselective Oxidative Dearomatization
2005
Further studies on the biosynthesis of chlorothricin.
1986
Alzheimer's Disease Amyloid Propagation by a Template-Dependent Dock-Lock Mechanism
2000
Long Time Dynamic Simulations: Exploring the Folding Pathways of an Alzheimer's Amyloid Aβ-Peptide
2002
Point Substitution in the Central Hydrophobic Cluster of a Human β-Amyloid Congener Disrupts Peptide Folding and Abolishes Plaque Competence
1996
Deposition of Monomeric, Not Oligomeric, Aβ Mediates Growth of Alzheimer's Disease Amyloid Plaques in Human Brain Preparations
1999