Citation Impact

Citing Papers

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
Modulation of immune cell reactivity with cis -binding Siglec agonists
2021 StandoutNobel
A small-molecule switch for Golgi sulfotransferases
2004 StandoutNobel
Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions
2011 StandoutNobel
Protein dynamics and distance determination by NOE measurements
1988
Automation of measurements and data evaluation in biomolecular NMR screening
2001
Fragment-based lead discovery
2004
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Crystal structure of plastocyanin from a green alga, Enteromorpha prolifera
1990
Determination of a high-quality nuclear magnetic resonance solution structure of the bovine pancreatic trypsin inhibitor and comparison with three crystal structures
1992 StandoutNobel
Modular click chemistry libraries for functional screens using a diazotizing reagent
2019 StandoutNatureNobel
NMR-based screening technologies
2003
Pharmacological inhibitors of MAPK pathways
2002
High-throughput crystallography for lead discovery in drug design
2002
The consequences of translational and rotational entropy lost by small molecules on binding to proteins
2002
A two‐dimensional 1H NMR study on Megasphaera elsdenii flavodoxin in the reduced state
1990
A rapamycin-selective 25-kDa immunophilin
1992
NMR Spectroscopy Techniques for Screening and Identifying Ligand Binding to Protein Receptors
2003
Dynamics of the Dihydrofolate Reductase-Folate Complex: Catalytic Sites and Regions Known To Undergo Conformational Change Exhibit Diverse Dynamical Features
1995
Tor, a Phosphatidylinositol Kinase Homologue, Controls Autophagy in Yeast
1998 StandoutNobel
Clicking class B GPCR ligands
2011
Protein structure determination in solution by two-dimensional and three-dimensional nuclear magnetic resonance spectroscopy
1990
Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy
1991 StandoutNatureNobel
Fragment-based lead discovery: a chemical update
2006
Relationship between nuclear magnetic resonance chemical shift and protein secondary structure
1991 Standout
The NMR solution conformation of unligated human cyclophilin A 1 1Edited by P. E. Wright
1997 StandoutNobel
Antagonists of protein–protein interactions
2000
Small-molecule inhibitors of protein–protein interactions: progressing towards the dream
2004 Standout
Copper Protein Structures
1991
Recent Developments in Fragment-Based Drug Discovery
2008
Transforming fragments into candidates: small becomes big in medicinal chemistry
2009
Strategies for Targeting Protein–Protein Interactions With Synthetic Agents
2005
Calcium oscillations increase the efficiency and specificity of gene expression
1998 StandoutNature
Features and development of Coot
2010 Standout
Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation
1992 StandoutNature
Inositol trisphosphate and calcium signalling
1993 StandoutNature
Discovery of novel inhibitors of the ZipA/FtsZ complex by NMR fragment screening coupled with structure-based design
2006
Cyclosporin A—cyclophilin complex formation A model based on X‐ray and NMR data
1992 StandoutNobel
Identification of compounds with binding affinity to proteins via magnetization transfer from bulk water*
2000
Recent advances in magic angle spinning solid state NMR of membrane proteins
2014
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
1991 Standout
A mammalian protein targeted by G1-arresting rapamycin–receptor complex
1994 StandoutNature
Determination of the NMR solution structure of the cyclophilin A-cyclosporin A complex
1994
Fragment-based lead discovery: leads by design
2005
A decade of fragment-based drug design: strategic advances and lessons learned
2007
Structure at 2.8 Å resolution of cytochrome c oxidase from Paracoccus denitrificans
1995 StandoutNatureNobel
Nmr in drug discovery
2002 StandoutNobel
Polarization transfer by cross-correlated relaxation in solution NMR with very large molecules
1999 StandoutNobel
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Transverse relaxation-optimized NMR spectroscopy with the outer membrane protein OmpX in dihexanoyl phosphatidylcholine micelles
2001 StandoutNobel
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
2018 StandoutNobel
TROSY-type Triple-Resonance Experiments for Sequential NMR Assignments of Large Proteins
1999 StandoutNobel
Structuring of metal–organic frameworks at the mesoscopic/macroscopic scale
2014 StandoutNobel
Molecular Recognition of Protein−Ligand Complexes:  Applications to Drug Design
1997 Standout
Siglec receptors impact mammalian lifespan by modulating oxidative stress
2015
Dynamical Contributions to Enzyme Catalysis:  Critical Tests of A Popular Hypothesis
2006 StandoutNobel
Comparison of the NMR solution structure and the x-ray crystal structure of rat metallothionein-2.
1992 StandoutNobel
Three-Dimensional Structure of an Angiotensin II-Fab Complex at 3 Å: Hormone Recognition by an Anti-Idiotypic Antibody
1992 Science
Conditional Glycosylation in Eukaryotic Cells Using a Biocompatible Chemical Inducer of Dimerization
2008 StandoutNobel
NMR relaxation and protein mobility
1993
TROSY in triple-resonance experiments: New perspectives for sequential NMR assignment of large proteins
1998 StandoutNobel
Integrating Fragment Assembly and Biophysical Methods in the Chemical Advancement of Small-Molecule Antagonists of IL-2:  An Approach for Inhibiting Protein−Protein Interactions
2004
Protein‐Templated Fragment Ligations—From Molecular Recognition to Drug Discovery
2017
Structure-based conformational preferences of amino acids
1999 StandoutNobel
Transverse Relaxation-Optimized Spectroscopy (TROSY) for NMR Studies of Aromatic Spin Systems in 13C-Labeled Proteins
1998 StandoutNobel
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
Generation of Candidate Ligands for Nicotinic Acetylcholine Receptors via in situ Click Chemistry with a Soluble Acetylcholine Binding Protein Template
2012 StandoutNobel
Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast
1991 StandoutScience
Identification and Functional Characterization of a Novel Acetylcholine-Binding Protein from the Marine Annelid Capitella teleta
2010
Solution NMR Techniques for Large Molecular and Supramolecular Structures
2002 StandoutNobel
Bipartite Ca 2+ -Binding Motif in C 2 Domains of Synaptotagmin and Protein Kinase C
1996 StandoutScienceNobel
The NMR–Rosetta capsid model of M13 bacteriophage reveals a quadrupled hydrophobic packing epitope
2015 StandoutNobel
Isotope labeling in solution protein assignment and structural analysis
1994
One-Dimensional Relaxation- and Diffusion-Edited NMR Methods for Screening Compounds That Bind to Macromolecules
1997
Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases
2002 StandoutScience
Fabrication of Oriented Silver-Functionalized RPM3 Films for the Selective Detection of Olefins
2013
Cancer Genome Landscapes
2013 StandoutScience
Signal sequence region of mitochondrial precursor proteins binds to mitochondrial import receptor.
1993 StandoutNobel
Charged surface residues of FKBP12 participate in formation of the FKBP12-FK506-calcineurin complex.
1992
Crystal structure of recombinant human T-cell cyclophilin A at 2.5 A resolution.
1991
Peptidyl‐Prolyl cis/trans Isomerases and Their Effectors
1994
Structure-Based Design of Novel, Urea-Containing FKBP12 Inhibitors
1996
Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples
2012 StandoutNobel
PRIM: Proximity imaging of green fluorescent protein-tagged polypeptides
1998 StandoutNobel
Charting biologically relevant chemical space: A structural classification of natural products (SCONP)
2005
Controlling Signal Transduction with Synthetic Ligands
1993 Science
Conformation of FK506 in X-ray structures of its complexes with human recombinant FKBP12 mutants
1995
Heterocyclic Nanographenes and Other Polycyclic Heteroaromatic Compounds: Synthetic Routes, Properties, and Applications
2016 Standout
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
Second-Site NMR Screening with a Spin-Labeled First Ligand
2000
Two Identical Noninteracting Sites in an Ion Channel Revealed by Proton Transfer
1994 StandoutScienceNobel
Receptor-Induced Conformation Change of the Immunosuppressant Cyclosporin A
1991 StandoutScienceNobel
Generation of Anti-trypanosomal Agents through Concise Synthesis and Structural Diversification of Sesquiterpene Analogues
2011 StandoutNobel

Works of Jonathan M. Moore being referenced

Crystal Structure of the Ectodomain Complex of the CGRP Receptor, a Class-B GPCR, Reveals the Site of Drug Antagonism
2010
Applications of SHAPES Screening in Drug Discovery
2002
Solution structure of FK506 bound to FKBP‐12
1992
Leveraging structural approaches: applications of NMR-based screening and X-ray crystallography for inhibitor design
2003
Solution Structure of FK506 Bound to the R42K, H87V Double Mutant of FKBP-12
1994
Dynamic NMR studies of ligand‐receptor interactions: Design and analysis of a rapidly exchanging complex of FKBP‐12/FK506 with a 24 kDa calcineurin fragment
1996
15N NMR Relaxation Studies of the FK506 Binding Protein: Dynamic Effects of Ligand Binding and Implications for Calcineurin Recognition
1994
NMR techniques for characterization of ligand binding: Utility for lead generation and optimization in drug discovery
1999
Proton NMR studies of plastocyanin from Scenedesmus obliquus: complete sequence-specific assignment, secondary structure analysis, and global fold
1988
NMR screening in drug discovery
1999
Nitrogen-15 NMR relaxation studies of the FK506 binding protein: Backbone dynamics of the uncomplexed receptor
1993
The SHAPES strategy: an NMR-based approach for lead generation in drug discovery
1999
Solution structure of the major binding protein for the immunosuppressant FK506
1991 Nature
Nuclear Magnetic Resonance-Based Approaches for Lead Generation in Drug Discovery
2002
Combinatorial triple-selective labeling as a tool to assist membrane protein backbone resonance assignment
2012
High-resolution solution structure of reduced French bean plastocyanin and comparison with the crystal structure of poplar plastocyanin
1991
Highly responsive fluorescent sensing of explosives taggant with an organic nanofibril film
2008
Three-Dimensional Solution Structure of Plastocyanin from the Green Alga Scenedesmus obliquus
1988 Science
Theory and Applications of NMR-Based Screening in Pharmaceutical Research
2004
Dynamics of a receptor-bound ligand by heteronuclear NMR: FK506 bound to FKBP-12
1993
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2026