Standout Papers
Citation Impact
Citing Papers
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
2012 StandoutScience
De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination
2003 StandoutNobel
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
RepeatModeler2 for automated genomic discovery of transposable element families
2020 Standout
Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program
2007 StandoutNobel
Evolution of new nonantibody proteins via iterative somatic hypermutation
2004 StandoutNobel
Characterization of a canine homolog of hepatitis C virus
2011 StandoutNobel
Caenorhabditis elegans ADAR editing and the ERI-6/7/MOV10 RNAi pathway silence endogenous viral elements and LTR retrotransposons
2020 StandoutNobel
HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype
2007 StandoutNobel
Viral protein U counteracts a human host cell restriction that inhibits HIV-1 particle production
2003
A macaque model of HIV-1 infection
2009
The IFITM Proteins Inhibit HIV-1 Infection
2010
Human Immunodeficiency Virus, Restriction Factors, and Interferon
2009
Identification of interferon-stimulated genes that attenuate Ebola virus infection
2020 StandoutNobel
Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts
2003 Nature
Intracellular interactions between APOBEC3G, RNA, and HIV-1 Gag: APOBEC3G multimerization is dependent on its association with RNA
2009
The RNA editing enzyme APOBEC1 induces somatic mutations and a compatible mutational signature is present in esophageal adenocarcinomas
2014
Genome-scale DNA methylation maps of pluripotent and differentiated cells
2008 StandoutNature
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
2016 StandoutNature
Immunity through DNA deamination
2003
Demethylation of 3-Methylthymine in DNA by Bacterial and Human DNA Dioxygenases
2004 StandoutNobel
X4 and R5 HIV-1 Have Distinct Post-entry Requirements for Uracil DNA Glycosylase during Infection of Primary Cells
2010 StandoutNobel
APOBEC3G DNA deaminase acts processively 3′ → 5′ on single-stranded DNA
2006
Intrinsic Cellular Defenses against Human Immunodeficiency Viruses
2012
Primary T-lymphocytes rescue the replication of HIV-1 DIS RNA mutants in part by facilitating reverse transcription
2008
The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA
2003 Nature
The cytoplasmic body component TRIM5α restricts HIV-1 infection in Old World monkeys
2004 StandoutNature
The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay
2003
Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu
2008 StandoutNature
APOBEC‐mediated interference with hepadnavirus production†
2005
RNA Editing Enzyme APOBEC1 and Some of Its Homologs Can Act as DNA Mutators
2002
Microbicides and other topical agents in the prevention of HIV and sexually transmitted infections
2007
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
Diverse functions for DNA and RNA editing in the immune system
2010
Retrovirus Restriction Factors
2004
Type I Interferons in Host Defense
2006
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
2007 StandoutNobel
HIV-1-Associated Uracil DNA Glycosylase Activity Controls dUTP Misincorporation in Viral DNA and Is Essential to the HIV-1 Life Cycle
2005
Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes
2017
Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G
2008 Nature
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business
2003
Human Retroviral Host Restriction Factors APOBEC3G and APOBEC3F Localize to mRNA Processing Bodies
2006
TRIM5 Suppresses Cross-Species Transmission of a Primate Immunodeficiency Virus and Selects for Emergence of Resistant Variants in the New Species
2010
Extensive mutagenesis experiments corroborate a structural model for the DNA deaminase domain of APOBEC3G
2007
Evolution of the AID/APOBEC Family of Polynucleotide (Deoxy)cytidine Deaminases
2004
Crystal Structure of the APOBEC3G Catalytic Domain Reveals Potential Oligomerization Interfaces
2010
Positioning of APOBEC3G/F Mutational Hotspots in the Human Immunodeficiency Virus Genome Favors Reduced Recognition by CD8+ T Cells
2014
DNA Deamination in Immunity: AID in the Context of Its APOBEC Relatives
2007
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx
2011 Nature
Interferon‐inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replication†
2006
Complementary function of the two catalytic domains of APOBEC3G
2005
DNA deamination in immunity
2005
Perturbation of the P-Body Component Mov10 Inhibits HIV-1 Infectivity
2010
Novel aspects of macromolecular repair and relationship to human disease
2004
Classification and characterization of human endogenous retroviruses; mosaic forms are common
2016
Mechanisms regulating imprinted genes in clusters
2007
Natural controlled HIV infection: Preserved HIV-specific immunity despite undetectable replication competent virus
2005
SIVagm genetic and biological features associated with replication
2003
Intrinsic immunity: a front-line defense against viral attack
2004
APOBEC3G Inhibits DNA Strand Transfer during HIV-1 Reverse Transcription
2007
APOBEC deaminases-mutases with defensive roles for immunity
2009
APOBEC3 inhibits mouse mammary tumour virus replication in vivo
2007 Nature
Structure, interaction and real‐time monitoring of the enzymatic reaction of wild‐type APOBEC3G
2009
DNA Editing by APOBECs: A Genomic Preserver and Transformer
2015
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
Uracil in DNA – occurrence, consequences and repair
2002
MX2 is an interferon-induced inhibitor of HIV-1 infection
2013 StandoutNatureNobel
Canine Hepacivirus NS3 Serine Protease Can Cleave the Human Adaptor Proteins MAVS and TRIF
2012
Crystal structure of Staphylococcus aureus tRNA adenosine deaminase TadA in complex with RNA
2006
Distinct Patterns of Cytokine Regulation of APOBEC3G Expression and Activity in Primary Lymphocytes, Macrophages, and Dendritic Cells
2006
DNA Methylation and Its Basic Function
2012 Standout
The AID/APOBEC family of nucleic acid mutators
2008
Virion-associated Uracil DNA Glycosylase-2 and Apurinic/Apyrimidinic Endonuclease Are Involved in the Degradation of APOBEC3G-edited Nascent HIV-1 DNA
2007
RNA-Dependent Oligomerization of APOBEC3G Is Required for Restriction of HIV-1
2009
Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome
2004
Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection
2013 Nature
Retroviral restriction by APOBEC proteins
2004
The interaction of HIV with dendritic cells: outcomes and pathways
2007 StandoutNobel
Requirement of Non-canonical Activity of Uracil DNA Glycosylase for Class Switch Recombination
2006 StandoutNobel
Moloney Leukemia Virus 10 (MOV10) Protein Inhibits Retrovirus Replication
2010
Inhibition of HIV-1 Particle Assembly by 2′,3′-Cyclic-Nucleotide 3′-Phosphodiesterase
2012 StandoutNobel
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
APOBEC3 Proteins Inhibit Human LINE-1 Retrotransposition
2006
Hepatitis B virus DNA is subject to extensive editing by the human deaminase APOBEC3C
2007
DNA Deamination Mediates Innate Immunity to Retroviral Infection
2003
Species-Specific Exclusion of APOBEC3G from HIV-1 Virions by Vif
2003
Antiviral Function of APOBEC3G Can Be Dissociated from Cytidine Deaminase Activity
2005
Mutator effects and mutation signatures of editing deaminases produced in bacteria and yeast
2011
The Dark Side of Activation-Induced Cytidine Deaminase: Relationship with Leukemia and Beyond
2006
BST-2/tetherin: Structural biology, viral antagonism, and immunobiology of a potent host antiviral factor
2012
IFITM Proteins Restrict Viral Membrane Hemifusion
2013
Cytidine Deamination of Retroviral DNA by Diverse APOBEC Proteins
2004
HIV-1 Vif Blocks the Antiviral Activity of APOBEC3G by Impairing Both Its Translation and Intracellular Stability
2003
Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS
2005 StandoutNobel
APOBEC-mediated viral restriction: not simply editing?
2007
Structural Model for Deoxycytidine Deamination Mechanisms of the HIV-1 Inactivation Enzyme APOBEC3G
2010
The ssDNA Mutator APOBEC3A Is Regulated by Cooperative Dimerization
2015
Intestinal macrophages and response to microbial encroachment
2010
Species-Specific Activity of SIV Nef and HIV-1 Vpu in Overcoming Restriction by Tetherin/BST2
2009
Intrinsic antiviral immunity
2012
APOBEC4, a New Member of the AID/APOBEC Family of Polynucleotide (Deoxy)Cytidine Deaminases Predicted by Computational Analysis
2005
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Carboxy-terminal domain of AID required for its mRNA complex formation in vivo
2009 StandoutNobel
Exosomes Packaging APOBEC3G Confer Human Immunodeficiency Virus Resistance to Recipient Cells
2008
APOBEC2 Is a Monomer in Solution: Implications for APOBEC3G Models
2012 StandoutNobel
Mice Deficient in APOBEC2 and APOBEC3
2005
Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells
2003
APOBEC3G/3F mediates intrinsic resistance of monocyte-derived dendritic cells to HIV-1 infection
2006 StandoutNobel
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
2015 StandoutNobel
Characterization of nonprimate hepacivirus and construction of a functional molecular clone
2015 StandoutNobel
Model Structure of Human APOBEC3G
2007
Identification of APOBEC3DE as Another Antiretroviral Factor from the Human APOBEC Family
2006
Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems
2016 StandoutScience
The paradox of Simian immunodeficiency virus infection in Sooty Mangabeys: active viral replication without disease progression
2004
Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response
2012 StandoutNobel
Biochemical Activities of Highly Purified, Catalytically Active Human APOBEC3G: Correlation with Antiviral Effect
2006
The multifaceted roles of RNA binding in APOBEC cytidine deaminase functions
2014
Antiviral Potency of APOBEC Proteins Does Not Correlate with Cytidine Deamination
2006
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Inhibition of Alpharetrovirus Replication by a Range of Human APOBEC3 Proteins
2007
Maintenance of viral suppression in HIV-1–infected HLA-B*57+ elite suppressors despite CTL escape mutations
2006
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Deaminase-independent inhibition of HIV-1 reverse transcription by APOBEC3G
2007
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
Constitutive Expression of AID Leads to Tumorigenesis
2003 StandoutNobel
Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS
2005 StandoutNobel
RNA editing of hepatitis B virus transcripts by activation-induced cytidine deaminase
2013 StandoutNobel
Dissociation of in vitro DNA deamination activity and physiological functions of AID mutants
2008 StandoutNobel
Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases in vitro and in vivo
2005
Human APOBEC3F Is Another Host Factor That Blocks Human Immunodeficiency Virus Type 1 Replication
2004
Myeloid differentiation and susceptibility to HIV-1 are linked to APOBEC3 expression
2007
Induction of Antiviral Cytidine Deaminases Does Not Explain the Inhibition of Hepatitis B Virus Replication by Interferons
2007
Reverse Transcriptase- and RNA Packaging Signal-Dependent Incorporation of APOBEC3G into Hepatitis B Virus Nucleocapsids
2008
Hypermutation of HIV-1 DNA in the Absence of the Vif Protein
2003 Science
Advantages and Disadvantages of Cytidine Deamination
2004
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Activation-induced cytidine deaminase shuttles between nucleus and cytoplasm like apolipoprotein B mRNA editing catalytic polypeptide 1
2004 StandoutNobel
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
2016 StandoutNobel
Antiviral Protein APOBEC3G Localizes to Ribonucleoprotein Complexes Found in P Bodies and Stress Granules
2006
Genetic Dissection of the Host Tropism of Human-Tropic Pathogens
2015
Human Immunodeficiency Virus Type 1 Vpr Induces the Degradation of the UNG and SMUG Uracil-DNA Glycosylases
2005
The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1
2004
De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination
2004 StandoutNobel
RNA-editing cytidine deaminase Apobec-1 is unable to induce somatic hypermutation in mammalian cells
2003 StandoutNobel
Works of Jonathan Choi being referenced
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
2002 StandoutNature
A Novel Variant of Inpp5f Is Imprinted in Brain, and Its Expression Is Correlated with Differential Methylation of an Internal CpG Island
2005