Standout Papers
Citation Impact
Citing Papers
Activation of the p62‐Keap1‐NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
2015 Standout
Increased Prevalence of Sleep-Disordered Breathing in Adults
2013 Standout
Oxidative Stress
2017 Standout
Hypoxia-regulated mechanisms in the pathogenesis of obesity and non-alcoholic fatty liver disease
2016
Pharmacologic Targeting of Hypoxia-Inducible Factors
2019 StandoutNobel
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
2019 StandoutNobel
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
2011 StandoutNobel
Regulation of hypoxia‐inducible factor‐α isoforms and redox state by carotid body neural activity in rats
2014 StandoutNobel
HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine
2015 StandoutNobel
Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease
2015
Myeloid Deletion of Nuclear Factor Erythroid 2−Related Factor 2 Increases Atherosclerosis and Liver Injury
2012
An Acquired and Endogenous Glycocalyx Forms a Bidirectional “Don’t Eat” and “Don’t Eat Me” Barrier to Phagocytosis
2020 StandoutNobel
Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature
2015
Polymorphism of Nrf2, an Antioxidative Gene, is Associated with Blood Pressure and Cardiovascular Mortality in Hemodialysis Patients
2014
Validation of the multiple sensor mechanism of the Keap1-Nrf2 system
2012
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
Cellular senescence in aging and age-related disease: from mechanisms to therapy
2015 Standout
Macrophages in the Pathogenesis of Atherosclerosis
2011 Standout
Toward clinical application of the Keap1–Nrf2 pathway
2013
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy
2021 Standout
Redox regulation of antioxidants, autophagy, and the response to stress: Implications for electrophile therapeutics
2014
The Science of Stroke: Mechanisms in Search of Treatments
2010 Standout
Endothelial Dysfunction in Obesity
2017
Genomic and epigenomic regulation of adipose tissue inflammation in obesity
2013
Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis (cyanoenone), a highly potent Nrf2 activator with a reversible covalent mode of action
2015
Macrophages in atherosclerosis: a dynamic balance
2013 Standout
Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases
2013
Obstructive sleep apnea and hypertrophic cardiomyopathy: A common and potential harmful combination
2012
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Redox status in mammalian cells and stem cells during culture in vitro: Critical roles of Nrf2 and cystine transporter activity in the maintenance of redox balance
2014
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association
2021 Standout
Neutrophil extracellular traps in immunity and disease
2017 Standout
Phenotypic modulation of macrophages in response to plaque lipids
2011
Role of obstructive sleep apnea in cardiovascular disease
2011
The absence of macrophage Nrf2 promotes early atherogenesis
2013
Effects of Prolonged Exposure to Hypobaric Hypoxia on Oxidative Stress, Inflammation and Gluco-Insular Regulation: The Not-So-Sweet Price for Good Regulation
2014
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
2010 Standout
Sleep-Disordered Breathing, Hypoxia, and Risk of Mild Cognitive Impairment and Dementia in Older Women
2011
The Metabolic Phenotype in Obesity: Fat Mass, Body Fat Distribution, and Adipose Tissue Function
2017 Standout
Sudden cardiac death and obesity
2014
Insight from Animal Models into the Cognitive Consequences of Adult Sleep-Disordered Breathing
2009
Obstructive Sleep Apnea is Associated with Increased Chemoreflex Sensitivity in Patients with Metabolic Syndrome
2012
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
2022 Standout
HIF-1α Activation by Intermittent Hypoxia Requires NADPH Oxidase Stimulation by Xanthine Oxidase
2015 StandoutNobel
Obstructive Sleep Apnea–Hypopnea and Incident Stroke
2010 Standout
Correction of Anemia with Epoetin Alfa in Chronic Kidney Disease
2006 Standout
Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases
2019 Standout
NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production?
2010 Standout
Obstructive Sleep Apnea and Hypoxemia Are Associated with Advanced Liver Histology in Pediatric Nonalcoholic Fatty Liver Disease
2013
Nrf2 is essential for cholesterol crystal‐induced inflammasome activation and exacerbation of atherosclerosis
2011
Impact of epoetin alfa on clinical end points in patients with chronic renal failure: A meta-analysis
2004
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
The rise of antioxidant signaling—The evolution and hormetic actions of Nrf2
2010
Cellular senescence: from physiology to pathology
2014 Standout
Nrf2 activation improves experimental rheumatoid arthritis
2023 StandoutNobel
Lipid Oxidation and Peroxidation in CNS Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities
2009
Deficiency of Nrf2 Accelerates the Effector Phase of Arthritis and Aggravates Joint Disease
2011
Pattern-Specific Sustained Activation of Tyrosine Hydroxylase by Intermittent Hypoxia: Role of Reactive Oxygen Species-Dependent Downregulation of Protein Phosphatase 2A and Upregulation of Protein Kinases
2009
AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease
2023 Standout
Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis
2014
HIF Prolyl 4-Hydroxylase-2 Inhibition Improves Glucose and Lipid Metabolism and Protects Against Obesity and Metabolic Dysfunction
2014
Role of Nrf2 in Oxidative Stress and Toxicity
2013 Standout
Nrf2and Cardiovascular Defense
2013
2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation
2014 Standout
Activation of Nrf2 in Endothelial Cells Protects Arteries From Exhibiting a Proinflammatory State
2009
Nuclear factor E2-related factor 2 deficiency impairs atherosclerotic lesion development but promotes features of plaque instability in hypercholesterolaemic mice
2018
NF-E2–Related Factor 2 Promotes Atherosclerosis by Effects on Plasma Lipoproteins and Cholesterol Transport That Overshadow Antioxidant Protection
2010
CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis
2016 Nature
Hypoxia Is Present in Murine Atherosclerotic Plaques and Has Multiple Adverse Effects on Macrophage Lipid Metabolism
2011
Adipocyte Pseudohypoxia Suppresses Lipolysis and Facilitates Benign Adipose Tissue Expansion
2014 StandoutNobel
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases
2017 Standout
DNA methylation in the central and efferent limbs of the chemoreflex requires carotid body neural activity
2017 StandoutNobel
Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology
2013 StandoutNobel
Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1α Degradation
2017 StandoutNobel
Effects of different acute hypoxic regimens on tissue oxygen profiles and metabolic outcomes
2011
Hypoxia and Adipocyte Physiology: Implications for Adipose Tissue Dysfunction in Obesity
2014
Nrf2 reduces allergic asthma in mice through enhanced airway epithelial cytoprotective function
2015
The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis
2018 Standout
2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation
2014 Standout
Complementary roles of gasotransmitters CO and H2S in sleep apnea
2017 StandoutNobel
Pathophysiology of Sleep Apnea
2010 Standout
The role of hypoxia‐inducible factors in carotid body (patho) physiology
2018 StandoutNobel
Vascular Smooth Muscle Cells in Atherosclerosis
2016 Standout
Reactive Oxygen Species in Metabolic and Inflammatory Signaling
2018 Standout
Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis
2016 Standout
Regulation of cell proliferation by hypoxia-inducible factors
2015 StandoutNobel
On the pivotal role of PPARa in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury
2016 StandoutNobel
Aging and Atherosclerosis
2012
The role of declining adaptive homeostasis in ageing
2017
Derivative of Bardoxolone Methyl, dh404, in an Inverse Dose-Dependent Manner Lessens Diabetes-Associated Atherosclerosis and Improves Diabetic Kidney Disease
2014
Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2
2010
Works of Jonathan C. Jun being referenced
Intermittent hypoxia has organ-specific effects on oxidative stress
2008
Obstructive sleep apnea and dyslipidemia: implications for atherosclerosis
2010
Intermittent Hypoxia Exacerbates Metabolic Effects of Diet‐Induced Obesity
2011
The Impact of Obstructive Sleep Apnea on Metabolic and Inflammatory Markers in Consecutive Patients with Metabolic Syndrome
2010
Metabolic Consequences of Sleep-Disordered Breathing
2009
Intermittent hypoxia inhibits clearance of triglyceride-rich lipoproteins and inactivates adipose lipoprotein lipase in a mouse model of sleep apnoea
2011
Effect of intermittent hypoxia on atherosclerosis in apolipoprotein E-deficient mice
2009
Metabolic consequences of intermittent hypoxia: Relevance to obstructive sleep apnea
2010
Sleep Disorders and the Development of Insulin Resistance and Obesity
2013
Disruption of Nrf2, a Key Inducer of Antioxidant Defenses, Attenuates ApoE-Mediated Atherosclerosis in Mice
2008
Metabolic Consequences of High-Fat Diet Are Attenuated by Suppression of HIF-1α
2012
Chronic Intermittent Hypoxia Induces Atherosclerosis via Activation of Adipose Angiopoietin-like 4
2013 StandoutNobel
Dyslipidemia and Atherosclerosis Induced by Chronic Intermittent Hypoxia Are Attenuated by Deficiency of Stearoyl Coenzyme A Desaturase
2008
Effect of deficiency in SREBP cleavage-activating protein on lipid metabolism during intermittent hypoxia
2007