Citation Impact
Citing Papers
Visualizing enveloping layer glycans during zebrafish early embryogenesis
2010 StandoutNobel
Epigenetic Repression of DNA Mismatch Repair by Inflammation and Hypoxia in Inflammatory Bowel Disease–Associated Colorectal Cancer
2009 StandoutNobel
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54
2003 Standout
The Periplasmic Cavity of LacY Mutant Cys154→Gly: How Open Is Open?
2013 StandoutNobel
Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4
2015 StandoutNobel
Synergy in a medicinal plant: Antimicrobial action of berberine potentiated by 5′-methoxyhydnocarpin, a multidrug pump inhibitor
2000 Standout
Mitigating risk in academic preclinical drug discovery
2015
Hypoxia — a key regulatory factor in tumour growth
2002 Standout
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
Chemoenzymatic Synthesis of Biotinylated Nucleotide Sugars as Substrates for Glycosyltransferases
2001
Cysteine 148 in the Lactose Permease of Escherichia coli Is a Component of a Substrate Binding Site. 1. Site-Directed Mutagenesis Studies
1994
Modular click chemistry libraries for functional screens using a diazotizing reagent
2019 StandoutNatureNobel
Fluorescent Labeling of Purified β2 Adrenergic Receptor
1995 StandoutNobel
Gi-Coupled GPCR Signaling Controls the Formation and Organization of Human Pluripotent Colonies
2009 StandoutNobel
Surface engineering of living myoblasts via selective periodate oxidation
2003
The role of helix VIII in the lactose permease of Escherichia coli: II. Site‐directed sulfhydryl modification
1997
Interactions between cellular proteins and morphologically different nanoscale aggregates of small molecules
2013
Molecular basis of the VHL hereditary cancer syndrome
2002 StandoutNobel
HIF2α cooperates with RAS to promote lung tumorigenesis in mice
2009 StandoutNobel
Molecular mechanisms of ligand binding, signaling, and regulation within the superfamily of G-protein-coupled receptors: molecular modeling and mutagenesis approaches to receptor structure and function
2004
GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
2010 Standout
HIF-1α Induces Genetic Instability by Transcriptionally Downregulating MutSα Expression
2005 StandoutNobel
Oxygen sensing by HIF hydroxylases
2004 StandoutNobel
Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling
2000 StandoutNobel
G Protein-coupled Receptors
1998 StandoutNobel
Dual Inhibitors of β-Amyloid Aggregation and Acetylcholinesterase as Multi-Target Anti-Alzheimer Drug Candidates
2013
Regulation of angiogenesis by hypoxia: role of the HIF system
2003 StandoutNobel
Metabolic Delivery of Ketone Groups to Sialic Acid Residues
1998 StandoutNobel
Drug repurposing: progress, challenges and recommendations
2018 Standout
Locating ligand-binding sites in 7tm receptors by protein engineering
1994
Failure to prolyl hydroxylate hypoxia‐inducible factor α phenocopies VHL inactivation in vivo
2006 StandoutNobel
The unusual enzymology of ATP synthase
1987 StandoutNobel
The kamikaze approach to membrane transport
2001
Resolution of NADH:ubiquinone oxidoreductase from bovine heart mitochondria into two subcomplexes, one of which contains the redox centers of the enzyme
1992 StandoutNobel
Site-directed Alkylation of LacY: Effect of the Proton Electrochemical Gradient
2007
Cysteine-Scanning Mutagenesis of Putative Helix VII in the Lactose Permease of Escherichia coli
1994
Sequences of 20 subunits of NADH: Ubiquinone oxidoreductase from bovine heart mitochondria
1992 StandoutNobel
Aspartate Substitutions Establish the Concerted Action of P-region Glutamates in Repeats I and III in Forming the Protonation Site of L-type Ca2+ Channels
1997
The ChEMBL database in 2017
2016 Standout
Selection of Mutant CHO Cells with Constitutive Activation of the HIF System and Inactivation of the von Hippel-Lindau Tumor Suppressor
2001 StandoutNobel
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
The respiratory‐chain NADH dehydrogenase (complex I) of mitochondria
1991
Discovery and resupply of pharmacologically active plant-derived natural products: A review
2015 Standout
A FlAsH-based FRET approach to determine G protein–coupled receptor activation in living cells
2005 StandoutNobel
Dynamics of Lactose Permease of Escherichia coli Determined by Site-Directed Chemical Labeling and Fluorescence Spectroscopy
1995
Computational Drug Repositioning: From Data to Therapeutics
2013
Cysteine scanning mutagenesis of putative helix XI in the lactose permease of Escherichia coli
1993
Direct incorporation of unprotected ketone groups into peptides during solid-phase synthesis: Application to the one-step modification of peptides with two different biophysical probes for FRET
1998 StandoutNobel
Acid potentiation of the capsaicin receptor determined by a key extracellular site
2000 StandoutNobel
Proton-dependent multidrug efflux systems
1996
Plasmon-Waveguide Resonance Studies of Ligand Binding to the Human β2-Adrenergic Receptor
2004 StandoutNobel
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
The EMBL-EBI search and sequence analysis tools APIs in 2019
2019 Standout
In vitro attachment of mono- and oligosaccharides to surface glycoconjugates of intact cells.
1986
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1
2004 StandoutNobel
SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules
2019 Standout
Agonist-induced conformational changes in the G-protein-coupling domain of the β 2 adrenergic receptor
2001 StandoutNobel
Homogeneous Glycopeptides and Glycoproteins for Biological Investigation
2002 StandoutNobel
PubChem 2023 update
2022 Standout
Functional π-Gelators and Their Applications
2014 Standout
Uncovering Molecular Mechanisms Involved in Activation of G Protein-Coupled Receptors
2000
PubChem 2019 update: improved access to chemical data
2018 Standout
Evolutionary mix-and-match with MFS transporters II
2013
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
2020 StandoutNobel
Fluorosulfuryl Isocyanate Enabled SuFEx Ligation of Alcohols and Amines
2021 StandoutNobel
Use of site-directed mutagenesis to study the mechanism of a membrane transport protein
1987
The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets
2020 Standout
Evolutionary mix-and-match with MFS transporters
2013
Probing Glycosyltransferase Activities with the Staudinger Ligation
2003 StandoutNobel
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry
2020 StandoutNobel
Role ofVHLGene Mutation in Human Cancer
2004 StandoutNobel
Works of Jonathan A. Lee being referenced
Stimulation of c-fos and c-jun gene expression and down-regulation of proenkephalin gene expression in C6 glioma cells by endothelin-1
1992
Open Innovation for Phenotypic Drug Discovery: The PD2 Assay Panel
2011
Opportunities and challenges in phenotypic drug discovery: an industry perspective
2017
Lysine 182 of Endothelin B Receptor Modulates Agonist Selectivity and Antagonist Affinity: Evidence for the Overlap of Peptide and Non-peptide Ligand Binding Sites
1994
Modern Phenotypic Drug Discovery Is a Viable, Neoclassic Pharma Strategy
2012
Neoclassic Drug Discovery: The Case for Lead Generation Using Phenotypic and Functional Approaches
2013
Effect of distance and orientation between arginine-302, histidine-322, and glutamate-325 on the activity of lac permease from Escherichia coli
1989
Characterization of site-directed mutants in the lac permease of Escherichia coli. 2. Glutamate-325 replacements
1989
Labeling of the glycoprotein subunit of sodium-potassium ATPase with fluorescent probes
1985
Role of cysteine residues in the lac permease of Escherichia coli
1987