Jonathan A. Beagan

The promise and challenge of therapeutic genome editing

The Role of Autophagy in Parkinson's Disease

Parkinson disease

Gene therapy for neurological disorders: progress and prospects

Alpha-synuclein: Pathology, mitochondrial dysfunction and neuroinflammation in Parkinson’s disease

Ageing as a risk factor for neurodegenerative disease

Effective gene expression prediction from sequence by integrating long-range interactions

Autophagy in Human Health and Disease

Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors

Is Modulation of Oxidative Stress an Answer? The State of the Art of Redox Therapeutic Actions in Neurodegenerative Diseases

Adeno-associated virus vector as a platform for gene therapy delivery

Clinical tests of neurotrophic factors for human neurodegenerative diseases, part 2: Where do we stand and where must we go next?

The next generation of CRISPR–Cas technologies and applications

Predicting 3D genome folding from DNA sequence with Akita

Glucocerebrosidase deficiency promotes protein aggregation through dysregulation of extracellular vesicles

Adeno-Associated Virus-Based Gene Therapy for CNS Diseases

Exosomes

Erratum: Gene therapy for neurological disorders: progress and prospects

Adeno‐associated virus–delivered artificial microRNA extends survival and delays paralysis in an amyotrophic lateral sclerosis mouse model

Conditional Recruitment to a DNA-Bound CRISPR–Cas Complex Using a Colocalization-Dependent Protein Switch

Oxidative Stress: A Key Modulator in Neurodegenerative Diseases

CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks

Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons

Widespread neuron-specific transgene expression in brain and spinal cord following synapsin promoter-driven AAV9 neonatal intracerebroventricular injection

ALS-associated peripherin spliced transcripts form distinct protein inclusions that are neuroprotective against oxidative stress

LADL: light-activated dynamic looping for endogenous gene expression control

YY1 and CTCF orchestrate a 3D chromatin looping switch during early neural lineage commitment

Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice

A Nurr1 Agonist Causes Neuroprotection in a Parkinson’s Disease Lesion Model Primed with the Toll-Like Receptor 3 dsRNA Inflammatory Stimulant Poly(I:C)