Citation Impact
Citing Papers
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α
2007 Standout
Jinx , an MCMV susceptibility phenotype caused by disruption of Unc13d : a mouse model of type 3 familial hemophagocytic lymphohistiocytosis
2007 StandoutNobel
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
2005 StandoutScience
Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47
2003 StandoutScience
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
2004 StandoutNobel
Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators
2006 Standout
Biological Control through Regulated Transcriptional Coactivators
2004
‘Green revolution’ genes encode mutant gibberellin response modulators
1999 StandoutNature
Targeted Disruption of the Stat1 Gene in Mice Reveals Unexpected Physiologic Specificity in the JAK–STAT Signaling Pathway
1996 Standout
Differential Activation of Acute Phase Response Factor/Stat3 and Stat1 via the Cytoplasmic Domain of the Interleukin 6 Signal Transducer gp130
1996
GAS Elements: A Few Nucleotides with a Major Impact on Cytokine-Induced Gene Expression
1997
The Carboxyl-terminal Domains of gp130-related Cytokine Receptors Are Necessary for Suppressing Embryonic Stem Cell Differentiation
1999
Pharmacokinetics and Pharmacodynamics of Nonsteroidal Androgen Receptor Ligands
2006
The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation
1998 StandoutNature
Targeted Disruption of the Mouse Stat1 Gene Results in Compromised Innate Immunity to Viral Disease
1996
Isolation and Characterization of the Human gp130 Promoter
1997
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Anabolic steroid-induced hypogonadism – Towards a unified hypothesis of anabolic steroid action
2009
Oncogenic kinase signalling
2001 StandoutNature
Identification of a Stat Gene That Functions in Drosophila Development
1996
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells
1999 Standout
Shared Principles in NF-κB Signaling
2008 Standout
Cross-talk between nuclear receptors and nuclear factor κB
2006
The Structure, Regulation and Function of the Janus Kinases (JAKs) and the Signal Transducers and Activators of Transcription (STATs)
1997
Components of a stat recognition code: Evidence for two layers of molecular selectivity
1995
Stat3 as an Oncogene
1999 Standout
Three-dimensional structure of the Stat3β homodimer bound to DNA
1998 Nature
Regulation of Chemokine Expression by Antiinflammatory Cytokines
2002
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
2007 StandoutNature
Stat2 Is a Transcriptional Activator That Requires Sequence-specific Contacts Provided by Stat1 and p48 for Stable Interaction with DNA
1997
The virus battles: IFN induction of the antiviral state and mechanisms of viral evasion
2001
A family of cytokine-inducible inhibitors of signalling
1997 StandoutNature
STAT3 Participates in Transcriptional Activation of the C-reactive Protein Gene by Interleukin-6
1996
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Disruption of the Jak1 Gene Demonstrates Obligatory and Nonredundant Roles of the Jaks in Cytokine-Induced Biologic Responses
1998 Standout
STATs in oncogenesis
2000 Standout
Immunity, Inflammation, and Cancer
2010 Standout
Signaling—2000 and Beyond
2000 Standout
STAT3-iNOS Signaling Mediates EGFRvIII-Induced Glial Proliferation and Transformation
2012
Influence of Subunit Combinations on Signaling by Receptors for Oncostatin M, Leukemia Inhibitory Factor, and Interleukin-6
1997
Differential Activation of Acute Phase Response Factor/STAT3 and STAT1 via the Cytoplasmic Domain of the Interleukin 6 Signal Transducer gp130
1996
Metabolic control through the PGC-1 family of transcription coactivators
2005 Standout
The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen
1998 Standout
Other Kinases Can Substitute for Jak2 in Signal Transduction by Interferon-γ
1996
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer
2017 Standout
Selective androgen receptor modulators as function promoting therapies
2009
Signals through gp130 upregulate bcl-x gene expression via STAT1-binding cis-element in cardiac myocytes.
1997
Ockham's Razor and Selective Androgen Receptor Modulators (SARMs): Are We Overlooking the Role of 5 -Reductase?
2007
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α
2006 Standout
Cytokine Signaling in 2002
2002 Standout
IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity
2001 StandoutNature
Selective glucocorticoid receptor nonsteroidal ligands completely antagonize the dexamethasone mediated induction of enzymes involved in gluconeogenesis and glutamine metabolism
2004
STAT signaling in head and neck cancer
2000
Jak2 Is Essential for Signaling through a Variety of Cytokine Receptors
1998 Standout
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
1996 StandoutNatureNobel
The role of IL-6 and STAT3 in inflammation and cancer
2005 Standout
Antibacterial drug discovery in the resistance era
2016 StandoutNature
The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells
2003 StandoutNobel
Cytokine receptor signalling
1995 Nature
Cell Signaling by Receptor Tyrosine Kinases
2000 Standout
STATs: transcriptional control and biological impact
2002 Standout
Impact of high-throughput screening in biomedical research
2011 Standout
Steroidal Androgens and Nonsteroidal, Tissue-Selective Androgen Receptor Modulator, S-22, Regulate Androgen Receptor Function through Distinct Genomic and Nongenomic Signaling Pathways
2008
New Approaches to Olefin Cross-Metathesis
1999 StandoutNobel
Interleukin-6 family of cytokines and gp130
1995
STAT3 Is Required for the gp130-mediated Full Activation of the c-myc Gene
1999
STATs and Gene Regulation
1997 StandoutScience
The MurineDUB-1Gene Is Specifically Induced by the βc Subunit of the Interleukin-3 Receptor
1996
The Carboxyl Terminus of the Granulocyte Colony- Stimulating Factor Receptor, Truncated in Patients with Severe Congenital Neutropenia/Acute Myeloid Leukemia, Is Required for SH2-Containing Phosphatase-1 Suppression of Stat Activation
2001
Structure of the Amino-Terminal Protein Interaction Domain of STAT-4
1998 Science
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Generation and reproductive phenotypes of mice lacking estrogen receptor β
1998 StandoutNobel
Nuclear hormone receptors: ligand-activated regulators of transcription and diverse cell responses
1996
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
1998 Standout
Requirements for Interleukin-4-Induced Gene Expression and Functional Characterization of Stat6
1996
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Jaks, STATs, Cytokine Signal Transduction, and Immunoregulation: Are We There Yet?
1997
Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects
2003
DNA Binding Specificity of Different STAT Proteins
2001
Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma.
1996
Stat3 Activation by Src Induces Specific Gene Regulation and Is Required for Cell Transformation
1998
Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells.
1997
Adverse Health Consequences of Performance-Enhancing Drugs: An Endocrine Society Scientific Statement
2013 Standout
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
Specific Inhibition of Stat3 Signal Transduction by PIAS3
1997 StandoutScience
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Selective androgen receptor modulators in preclinical and clinical development
2008
Solution-phase combinatorial synthesis: Convergent multiplication of diversity via the olefin metathesis reaction
1998
A Small, Nonpeptidyl Mimic of Granulocyte-Colony- Stimulating Factor
1998 Science
Phosphatidylinositol-3-Kinase Signaling Is Required for Erythropoietin-Mediated Acute Protection Against Myocardial Ischemia/Reperfusion Injury
2004 StandoutNobel
Deletion of the Carboxyl-Terminal Transactivation Domain of MGF-Stat5 Results in Sustained DNA Binding and a Dominant Negative Phenotype
1996
Molecular determinants of tissue selectivity in estrogen receptor modulators
1997
Role of the Stat4 N Domain in Receptor Proximal Tyrosine Phosphorylation
2000
Differential Ligand Activation of Estrogen Receptors ERα and ERβ at AP1 Sites
1997 StandoutScience
The Interplay between the Glucocorticoid Receptor and Nuclear Factor-κB or Activator Protein-1: Molecular Mechanisms for Gene Repression
2003
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
The Significance of Tetramerization in Promoter Recruitment by Stat5
1999
Works of Jon Rosen being referenced
An Orally Active Selective Androgen Receptor Modulator Is Efficacious on Bone, Muscle, and Sex Function with Reduced Impact on Prostate
2006
The Intracellular Receptor and Signal Transducers and Activators of Transcription Factor Superfamilies: Novel Targets for Small-Molecule Drug Discovery
1995
A Nonsteroidal Glucocorticoid Receptor Antagonist
2003
Discovery and characterization of a selective, nonpeptidyl thrombopoietin receptor agonist
2005
Novel, non-steroidal, selective androgen receptor modulators (SARMs) with anabolic activity in bone and muscle and improved safety profile.
2002
Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity.
1995
Identification of a Pharmacophore for Thrombopoietic Activity of Small, Non-Peptidyl Molecules. 1. Discovery and Optimization of Salicylaldehyde Thiosemicarbazone Thrombopoietin Mimics
2002
A Novel Antiinflammatory Maintains Glucocorticoid Efficacy with Reduced Side Effects
2003
Rapid activation of the STAT3 transcription factor by granulocyte colony-stimulating factor
1994
Identification of a Pharmacophore for Thrombopoietic Activity of Small, Non-Peptidyl Molecules. 2. Rational Design of Naphtho[1,2-d]imidazole Thrombopoietin Mimics
2002