Standout Papers

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells 2012 2026 2016 2021 1.9k
  1. A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells (2012)
    Christian Schulz, Elisa Gomez Perdiguero et al. Science

Citation Impact

Citing Papers

Why highly expressed proteins evolve slowly
2005 StandoutNobel
Specification of tissue-resident macrophages during organogenesis
2016 Science
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
The pancreas anatomy conditions the origin and properties of resident macrophages
2015
Requirement of the mouse I-mfa gene for placental development and skeletal patterning
1998
Macrophage Ontogeny Underlies Differences in Tumor-Specific Education in Brain Malignancies
2016
Macrophage Regulation of Tumor Responses to Anticancer Therapies
2013
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Discovery of Potent Orally Active Thrombin Receptor (Protease Activated Receptor 1) Antagonists as Novel Antithrombotic Agents
2005
The Lifespan and Turnover of Microglia in the Human Brain
2017
Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease
2014
Regulation of macrophage development and function in peripheral tissues
2015
Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression
2017
Origin of monocytes and macrophages in a committed progenitor
2013
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
1995 StandoutNobel
A Robust and Highly Efficient Immune Cell Reprogramming System
2009
Social and environmental risk factors in the emergence of infectious diseases
2004
A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis
1991
Initiation of adult myelopoiesis can occur in the absence of c-Myb whereas subsequent development is strictly dependent on the transcription factor
2000
Global trends in emerging infectious diseases
2008 StandoutNature
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Host tissue determinants of tumour immunity
2019
Tissue-Resident Macrophage Ontogeny and Homeostasis
2016
C-type lectins in immunity and homeostasis
2018
Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities
2014
Astrocytes and Microglia as Major Players of Myelin Production in Normal and Pathological Conditions
2020
Type I iodothyronine deiodinase is a selenocysteine-containing enzyme
1991 StandoutNature
Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
2014 StandoutNature
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
Pulmonary macrophage transplantation therapy
2014 Nature
Heme-Mediated SPI-C Induction Promotes Monocyte Differentiation into Iron-Recycling Macrophages
2014 Nobel
Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors
2012
A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model
2013
Interplay of Pu.1 and Gata1 Determines Myelo-Erythroid Progenitor Cell Fate in Zebrafish
2005
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
2008 Standout
Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1
1991 Nature
Intestinal macrophages: well educated exceptions from the rule
2013
Three N-terminal Variants of the AE2 Cl-/HCO3- Exchanger Are Encoded by mRNAs Transcribed from Alternative Promoters
1996
Tissue-resident macrophages
2013 Standout
Ribosome gymnastics—Degree of difficulty 9.5, style 10.0
1990
Developmental control of macrophage function
2017
C-Myb+ Erythro-Myeloid Progenitor-Derived Fetal Monocytes Give Rise to Adult Tissue-Resident Macrophages
2015
Direct lineage conversions: unnatural but useful?
2011
Stepwise Reprogramming of B Cells into Macrophages
2004
The Oncogenic Cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development
1994 StandoutNobel
Gene Ontology: tool for the unification of biology
2000 Standout
Antagonism between C/EBPβ and FOG in eosinophil lineage commitment of multipotent hematopoietic progenitors
2000
Forcing cells to change lineages
2009 Nature
CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation
2016
Analyzing real-time PCR data by the comparative CT method
2008 Standout
Tissue-Specific Signals Control Reversible Program of Localization and Functional Polarization of Macrophages
2014
Isolation and functional analysis of a Kluyveromyces lactis RAP1 homologue
1994
VIRAL HEMORRHAGIC FEVERS AND HANTAVIRUS INFECTIONS IN THE AMERICAS
1998
Factors regulating microglia activation
2013
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
Macrophage-Restricted Interleukin-10 Receptor Deficiency, but Not IL-10 Deficiency, Causes Severe Spontaneous Colitis
2014
Runaway telomere elongation caused by telomerase RNA gene mutations
1995 StandoutNatureNobel
Long-Term Studies of Hantavirus Reservoir Populations in the Southwestern United States: A Synthesis
1999
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
2005 StandoutNatureNobel
The glioma-amplified sequence 41 gene (GAS41) is a direct Myb target gene
2004
Evidence for specific selenium target tissues and new biologically important selenoproteins
1988
The nuclear receptor LXRα controls the functional specialization of splenic macrophages
2013
Alveolar macrophages: plasticity in a tissue-specific context
2014
Pioneer transcription factors: establishing competence for gene expression
2011
A timeline of tumour-associated macrophage biology
2023
Host microbiota constantly control maturation and function of microglia in the CNS
2015 Standout
Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats
1996 StandoutNatureNobel
Identification of a unique TGF-β–dependent molecular and functional signature in microglia
2013 Standout
Chicken “erythroid” cells transformed by the Gag-Myb-Ets-encoding E26 leukemia virus are multipotent
1992
Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice
2014
Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity
2014
Platelets in inflammation and atherogenesis
2005 Standout
A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation
2013
Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages
2014
Detection of functional haematopoietic stem cell niche using real-time imaging
2008 Nature
Microglia: unique and common features with other tissue macrophages
2014
Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis
2012 Standout
Tissue-Resident CD169+ Macrophages Form a Crucial Front Line against Plasmodium Infection
2016
Microglia and monocyte-derived macrophages: functionally distinct populations that act in concert in CNS plasticity and repair
2013
PU.1 Is Required for the Developmental Progression of Multipotent Progenitors to Common Lymphoid Progenitors
2018
Macrophages as regulators of tumour immunity and immunotherapy
2019 Standout
Monocytes and macrophages: developmental pathways and tissue homeostasis
2014
Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis
2016
Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation
2014
Erythro-myeloid progenitors: “Definitive” hematopoiesis in the conceptus prior to the emergence of hematopoietic stem cells
2013
Oncofetal reprogramming in tumour development and progression
2022
Myeloid Lineage Commitment from the Hematopoietic Stem Cell
2007
Diversification of haematopoietic stem cells to specific lineages
2000
Gut Microbiota Promote Hematopoiesis to Control Bacterial Infection
2014
Removing the Vertebrate-Specific TBP N Terminus Disrupts Placental β2m-Dependent Interactions with the Maternal Immune System
2002 StandoutNobel
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Ly6Chi Monocytes in the Inflamed Colon Give Rise to Proinflammatory Effector Cells and Migratory Antigen-Presenting Cells
2012
Re(de)fining the dendritic cell lineage
2012
Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
2014 Standout
Origin and Functions of Tissue Macrophages
2014
Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
2012 Standout
Microglial Corpse Clearance: Lessons From Macrophages
2020
A Combination of Ontogeny and CNS Environment Establishes Microglial Identity
2018
Reciprocal Activation of GATA-1 and PU.1 Marks Initial Specification of Hematopoietic Stem Cells into Myeloerythroid and Myelolymphoid Lineages
2007
Imaging macrophages with nanoparticles
2014
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Nuclear Reprogramming in Cells
2008 StandoutScienceNobel
Generation of Lymphohematopoietic Cells from Embryonic Stem Cells in Culture
1994 StandoutScienceNobel
The human AQP4 gene: definition of the locus encoding two water channel polypeptides in brain.
1996 StandoutNobel
In Vitro Development of Primitive and Definitive Erythrocytes from Different Precursors
1996 StandoutScienceNobel
Missense misreading of asparagine codons as a function of codon identity and context.
1987
Rap1 protein regulates telomere turnover in yeast
1998 StandoutNobel
The predicted translation product of a cardiac AE3 mRNA contains an N terminus distinct from that of the brain AE3 Cl-/HCO3- exchanger. Cloning of a cardiac AE3 cDNA, organization of the AE3 gene, and identification of an alternative transcription initiation site.
1992
Platelet-collagen interaction: is GPVI the central receptor?
2003
Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system
2016 StandoutNobel
Errors and alternatives in reading the universal genetic code
1989
Proliferation of multipotent hematopoietic cells controlled by a truncated erythropoietin receptor transgene.
1996 StandoutNobel
Transmembrane Collagen Receptors
2011
Finding errors in DNA sequences.
1992 StandoutNobel
Nonstructural proteins nsP3 and nsP4 of Ross River and O'Nyong-nyong viruses: Sequence and comparison with those of other alphaviruses
1988 StandoutNobel
Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival
2014
Macrophages of distinct origins contribute to tumor development in the lung
2018
Brain conditioning is instrumental for successful microglia reconstitution following hematopoietic stem cell transplantation
2012
Mutagenesis of the in-frame opal termination codon preceding nsP4 of Sindbis virus: studies of translational readthrough and its effect on virus replication
1989 StandoutNobel
Selenocysteine tRNA[Ser]Sec gene is ubiquitous within the animal kingdom.
1990
Evolution of the genome and the genetic code: selection at the dinucleotide level by methylation and polyribonucleotide cleavage.
1989 StandoutNobel
Emerging Infectious Diseases of Wildlife-- Threats to Biodiversity and Human Health
2000 StandoutScience
Single-nanometer iron oxide nanoparticles as tissue-permeable MRI contrast agents
2021 StandoutNobel
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
2012 StandoutNobel
Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac–derived macrophages
2012
Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure.
1995
Transcriptome analysis highlights the conserved difference between embryonic and postnatal-derived alveolar macrophages
2015
Immature hematopoietic stem cells undergo maturation in the fetal liver
2012
Selenocysteine tRNA[Ser]Sec Gene Is Ubiquitous within the Animal Kingdom
1990
Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells.
1994
Alternative RNA Splicing Produces Multiple Forms of c-Myb with Unique Transcriptional Activities
2008
Lethal thalassemia after insertional disruption of the mouse major adult beta-globin gene.
1993 StandoutNobel
Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III
1997 StandoutNobel
Regulation of B Lymphocyte and Macrophage Development by Graded Expression of PU.1
2000 Science
Differentiation plasticity of hematopoietic cells
2002
A mouse model for beta 0-thalassemia.
1995 StandoutNobel
Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF
2013
A Crucial Role of Glycoprotein VI for Platelet Recruitment to the Injured Arterial Wall In Vivo
2002
Molecular cloning and functional expression of a human cDNA encoding the antimutator enzyme 8-hydroxyguanine-DNA glycosylase
1997 StandoutNobel
Quantum dot/antibody conjugates for in vivo cytometric imaging in mice
2015 StandoutNobel
Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD): a vehicle for direct determination of three-dimensional structure.
1990 Standout
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
2014 StandoutNobel
Regulated Expression of Globin Chains and the Erythroid Transcription Factor GATA-1 during Erythropoiesis in the Developing Mouse
1990
Macrophage plasticity and polarization in tissue repair and remodelling
2012 Standout
The Gene for Erythropoietin Receptor Is Expressed in Multipotential Hematopoietic and Embryonal Stem Cells: Evidence for Differentiation Stage-Specific Regulation
1992
Isolation and characterization of the complementary DNA for sheep seminal vesicle prostaglandin endoperoxide synthase (cyclooxygenase).
1988
The gene for erythropoietin receptor is expressed in multipotential hematopoietic and embryonal stem cells: evidence for differentiation stage-specific regulation.
1992
Cotranslational insertion of selenocysteine into formate dehydrogenase from Escherichia coli directed by a UGA codon.
1987
Macrophages: Gatekeepers of Tissue Integrity
2013
Myb-Related Schizosaccharomyces pombecdc5p Is Structurally and Functionally Conserved in Eukaryotes
1998

Works of Jon Frampton being referenced

Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region
2011
A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells
2012 StandoutScience
RCAS/SCL-TVA Animal Model Allows Targeted Delivery of Polyoma Middle T Oncogene to Vascular Endothelial Progenitors In vivo and Results in Hemangioma Development
2008
Patterns of Association with Host and Habitat: Antibody Reactive with Sin Nombre Virus in Small Mammals in the Major Biotic Communities of the Southwestern United States
1997
Proposed structure for the DNA-binding domain of the Myb oncoprotein based on model building and mutational analysis
1991
Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level
2013
Manipulation of Mouse Hematopoietic Progenitors by Specific Retroviral Infection
2003
GATAAG; acis-control region binding an erythroid-specific nuclear factor with a role in globin and non-globin gene expression
1989
Thrombin‐induced conversion of fibrinogen to fibrin results in rapid platelet trapping which is not dependent on platelet activation or GPIb
2003
Mutations in v-myb alter the differentiation of myelomonocytic cells transformed by the oncogene
1990
Glycoprotein VI oligomerization in cell lines and platelets
2007
Integrin α2β1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and PLCγ2
2003
The structure of the mouse glutathione peroxidase gene: the selenocysteine in the active site is encoded by the ‘termination’ codon, TGA.
1986
Critical roles for c-Myb in lymphoid priming and early B-cell development
2010
v-Myb of E26 leukemia virus up-regulates bcl-2 and suppresses apoptosis in myeloid cells.
1996
Lineage commitment of transformed haematopoietic progenitors is determined by the level of PKC activity.
1996
Climatic and Environmental Patterns Associated with Hantavirus Pulmonary Syndrome, Four Corners Region, United States
1999
Synergy between the NF-E1 erythroid-specific transcription factor and the CACCC factor in the erythroid-specific promoter of the human porphobilinogen deaminase gene.
1990
Podoplanin and CLEC-2 drive cerebrovascular patterning and integrity during development
2015
GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts.
1995
The Role of ITAM- and ITIM-coupled Receptors in Platelet Activation by Collagen
2001
v-Myb DNA binding is required to block thrombocytic differentiation of Myb-Ets-transformed multipotent haematopoietic progenitors.
1995
Platelet Adhesion Via Glycoprotein IIb Integrin Is Critical for Atheroprogression and Focal Cerebral Ischemia
2005
A functional Ets DNA-binding domain is required to maintain multipotency of hematopoietic progenitors transformed by Myb-Ets.
1994
Rankless by CCL
2026