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1988
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2006
Epigenetic Programming of Phenotypic Variations in Reproductive Strategies in the Rat Through Maternal Care
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Regulation of the preovulatory gonadotropin surge by endogenous steroids
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Cellular and molecular connections between sleep and synaptic plasticity
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When brain clocks lose track of time: cause or consequence of neuropsychiatric disorders
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2008
Chronic administration of neuropeptide Y into the lateral ventricle inhibits both the pituitary-testicular axis and growth hormone and insulin-like growth factor I secretion in intact adult male rats.
1996
Does PCOS have developmental origins?
2011
The adolescent brain and age-related behavioral manifestations
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2008
The genetics of the polycystic ovary syndrome
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Glial-neuronal interactions in the neuroendocrine control of mammalian puberty: Facilitatory effects of gonadal steroids
1999
Mechanisms underlying episodic gonadotropin-releasing hormone secretion
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Elevated androgens during puberty in female rhesus monkeys lead to increased neuronal drive to the reproductive axis: a possible component of polycystic ovary syndrome
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Insulin-Like Growth Factor 1 Physiology
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Neurobiological mechanisms underlying GnRH pulse generation by the hypothalamus
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Early Maturation of Gonadotropin-Releasing Hormone Secretion and Sexual Precocity after Exposure of Infant Female Rats to Estradiol or Dichlorodiphenyltrichloroethane1
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Gonadotropin Gene Modulation by Steroids and Gonadotropin-Releasing Hormone1
1996
Sex and gender: modifiers of health, disease, and medicine
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Rescue of Obesity-Induced Infertility in Female Mice due to a Pituitary-Specific Knockout of the Insulin Receptor
2010
Polycystic ovary syndrome and its developmental origins
2007
Identification and characterization of estrogen receptor ?-containing neurons projecting to the vicinity of the gonadotropin-releasing hormone perikarya in the rostral preoptic area of the rat
1999
The LHRH pulse generator: A mediobasal hypothalamic location
1995
Polycystic Ovary Syndrome
1995 Standout
Central nervous system control of food intake
2000 StandoutNature
Androgen excess fetal programming of female reproduction: a developmental aetiology for polycystic ovary syndrome?
2005
Circadian clock control of the cellular response to DNA damage
2010 StandoutNobel
A Guide for the Design of Pre-clinical Studies on Sex Differences in Metabolism
2017
Nrk, an X-linked Protein Kinase in the Germinal Center Kinase Family, Is Required for Placental Development and Fetoplacental Induction of Labor
2011 StandoutNobel
Polycystic ovary syndrome: etiology, pathogenesis and diagnosis
2011
Regulation of Gonadotropin-Releasing Hormone Secretion by Kisspeptin/Dynorphin/Neurokinin B Neurons in the Arcuate Nucleus of the Mouse
2009
Kisspeptin Neurons in the Ovine Arcuate Nucleus and Preoptic Area Are Involved in the Preovulatory Luteinizing Hormone Surge
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Physiology and Pathophysiology of Purinergic Neurotransmission
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Bioactive peptides in anterior pituitary cells
1994
Activation of Gonadotropin-Releasing Hormone Neurons by Kisspeptin as a Neuroendocrine Switch for the Onset of Puberty
2005
Polycystic Ovary Syndrome
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Central Administration of Antiserum to Vasoactive Intestinal Peptide Delays and Reduces Luteinizing Hormone and Prolactin Surges in Ovariectomized, Estrogen-Treated Rats
1999
REM sleep deprivation inhibits LTP in vivo in area CA1 of rat hippocampus
2005
Epigenetic Mechanism Underlying the Development of Polycystic Ovary Syndrome (PCOS)-Like Phenotypes in Prenatally Androgenized Rhesus Monkeys
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Molecular Biology of the Pituitary Gonadotropins
1990
Adolescent Anovulation: Maturational Mechanisms and Implications
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Regulation of Rat Luteinizing Hormone β Gene Expression in Transgenic Mice by Steroids and a Gonadotropin-Releasing Hormone Antagonist1
1995
Region-specific transcriptional changes following the three antidepressant treatments electro convulsive therapy, sleep deprivation and fluoxetine
2006
NEW EMBO MEMBERS' REVIEW: The ErbB signaling network: receptor heterodimerization in development and cancer
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Ontogeny of polycystic ovary syndrome and insulin resistance in utero and early childhood
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Effects of Immunoneutralization of Corticotropin-Releasing Hormone on Ultradian Rhythms of Plasma Adrenocorticotropin*
1990
Developmental reprogramming of reproductive and metabolic dysfunction in sheep: native steroids vs. environmental steroid receptor modulators
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The role of brain angiotensin II in the regulation of luteinizing hormone and prolactin secretion
1992
Differential effects of the N-methyl-d-aspartate and non-N-methyl-d-aspartate receptors of the excitatory amino acids system on LH and FSH secretion. Its effects on the hypothalamic luteinizing hormone releasing hormone during maturation in male rats
1996
Functional Fluorescent Ca2+ Indicator Proteins in Transgenic Mice under TET Control
2004 StandoutNobel
Intercellular interactions in the anterior pituitary
1994
Impact of environmental estrogens on Yfish considering the diversity of estrogen signaling
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Neurokinin B and the hypothalamic regulation of reproduction
2010
Rapid Insulinotropic Action of Low Doses of Bisphenol-A on Mouse and Human Islets of Langerhans: Role of Estrogen Receptor β
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Central injection of senktide, an NK3 receptor agonist, or neuropeptide Y inhibits LH secretion and induces different patterns of Fos expression in the rat hypothalamus
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Evidence that obesity and androgens have independent and opposing effects on gonadotropin production from puberty to maturity
2010
Dual Labelin SituHybridization Studies Provide Evidence that Luteinizing Hormone-Releasing Hormone Neurons Do Not Synthesize Messenger Ribonucleic Acid for μ, κ, or δ Opiate Receptors1
1997
Definition of Estrogen Receptor Pathway Critical for Estrogen Positive Feedback to Gonadotropin-Releasing Hormone Neurons and Fertility
2006
Role of leptin in the neuroendocrine response to fasting
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BMAL1 and CLOCK, Two Essential Components of the Circadian Clock, Are Involved in Glucose Homeostasis
2004
The Diagnosis of Polycystic Ovary Syndrome during Adolescence
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Prenatal Androgen Treatment Alters Body Composition and Glucose Homeostasis in Male Rats
2010
Neuroendocrine and behavioral effects of maternal exposure to oral bisphenol A in female mice
2014
Direct and Indirect Regulation of Gonadotropin-Releasing Hormone Neurons by Estradiol1
2003
Discovery of Potent Kisspeptin Antagonists Delineate Physiological Mechanisms of Gonadotropin Regulation
2009
Localization of oestrogen receptors in preoptic neurons containing neurotensin but not tyrosine hydroxylase, cholecystokinin or luteinizing hormone-releasing hormone in the male and female rat
1992
Fetal, infant, adolescent and adult phenotypes of polycystic ovary syndrome in prenatally androgenized female rhesus monkeys
2009
Disrupting effects of bifenthrin on ovulatory gene expression and prostaglandin synthesis in rat ovarian granulosa cells
2011
Aryl hydrocarbon receptor activation in lactotropes and gonadotropes interferes with estradiol-dependent and -independent preprolactin, glycoprotein alpha and luteinizing hormone beta gene expression
2010
Progesterone Advances the Diurnal Rhythm of Tuberoinfundibular Dopaminergic Neuronal Activity and the Prolactin Surge in Ovariectomized, Estrogen-Primed Rats and in Intact Proestrous Rats*
1998
The Kisspeptin/Neurokinin B/Dynorphin (KNDy) Cell Population of the Arcuate Nucleus: Sex Differences and Effects of Prenatal Testosterone in Sheep
2009
Involvement of 5-HT1A Receptors in Homeostatic and Stress-Induced Adaptive Regulations of Paradoxical Sleep: Studies in 5-HT1A Knock-Out Mice
2002
Pathophysiology of Human Visceral Obesity: An Update
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Testosterone regulation of cyclin E kinase: A key factor in determining gender differences in hepatocarcinogenesis
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Phytoestrogens and Gonadotropin-Releasing Hormone Pulse Generator Activity and Pituitary Luteinizing Hormone Release in the Rat*
2001
NPAS2 as a transcriptional regulator of non-rapid eye movement sleep: Genotype and sex interactions
2006
Role of endogenous opiates in the expression of negative feedback actions of androgen and estrogen on pulsatile properties of luteinizing hormone secretion in man.
1984
Evidence of a Role for Kisspeptin and Neurokinin B in Puberty of Female Sheep
2012
EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals
2015 Standout
Associations of Birthweight and Gestational Age with Reproductive and Metabolic Phenotypes in Women with Polycystic Ovarian Syndrome and Their First-Degree Relatives
2009
Disrupting the circadian clock: Gene-specific effects on aging, cancer, and other phenotypes
2011
Mechanisms of Insulin Action and Insulin Resistance
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Release rates of catecholamines, GABA and ?-endorphin in the preoptic area and the mediobasal hypothalamus of the rhesus monkey in push-pull perfusates: correlation with blood hormone levels
1986
Experimentally induced gestational androgen excess disrupts glucoregulation in rhesus monkey dams and their female offspring
2010
Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement
2009 Standout
Gonadotropin-Releasing Hormone Deficiency in the Human (Idiopathic Hypogonadotropic Hypogonadism and Kallmann’s Syndrome): Pathophysiological and Genetic Considerations
1998
Minireview: Kisspeptin/Neurokinin B/Dynorphin (KNDy) Cells of the Arcuate Nucleus: A Central Node in the Control of Gonadotropin-Releasing Hormone Secretion
2010
Binding studies of substance P anterior pituitary binding sites: changes in substance P binding sites during the rat estrous cycle
1985
In vivo studies on paracrine actions of pituitary angiotensin II in stimulating prolactin release in rats
1990
The Differential Effect of Atrazine on Luteinizing Hormone Release in Adrenalectomized Adult Female Wistar Rats1
2011
Effects of Castration and Chronic Steroid Treatments on Hypothalamic Gonadotropin-Releasing Hormone Content and Pituitary Gonadotropins in Male Wild-Type and Estrogen Receptor-α Knockout Mice
1998
Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?
1999 Standout
Control of Sleep and Wakefulness
2012
An upstream region of the rat luteinizing hormone β gene binds estrogen receptor and confers estrogen responsiveness
1989
Microglia Function in the Central Nervous System During Health and Neurodegeneration
2017 Standout
Excitatory Amino Acids: Evidence for a Role in the Control of Reproduction and Anterior Pituitary Hormone Secretion*
1997
Electrophysiology of hypothalamic magnocellular neurones secreting oxytocin and vasopressin
1982
Mechanisms of Estrogen Action
2001 Standout
Prevalence of Polycystic Ovary Syndrome in Women from Opposite-Sex Twin Pairs
2009
Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development inCaenorhabditis elegans
2008 StandoutNobel
Rhythmic Exocytosis Stimulated by GnRH-Induced Calcium Oscillations in Rat Gonadotropes
1993 Science
Early origins of polycystic ovary syndrome
2005
Generation and synchronization of gonadotropin-releasing hormone (GnRH) pulses: intrinsic properties of the GT1-1 GnRH neuronal cell line.
1992
A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis
1997 StandoutNobel
Diagnosis, Staging, and Management of Hepatocellular Carcinoma: 2018 Practice Guidance by the American Association for the Study of Liver Diseases
2018 Standout
Neuropeptide Y secretion increases in the paraventricular nucleus in association with increased appetite for food.
1991
Evidence for basal and stress-induced release of corticotropin releasing factor in the push-pull cannulated median eminence of conscious free-moving rats
1987
About Sleep's Role in Memory
2013 Standout
Prolactin: Structure, Function, and Regulation of Secretion
2000 Standout
Lactation alters neuropeptide-Y and proopiomelanocortin gene expression in the arcuate nucleus of the rat.
1993
Activity of vasoactive intestinal peptide and serotonin in the paraventricular nucleus reflects the periodicity of the endogenous stimulatory rhythm regulating prolactin secretion.
1992
Arcuate Kisspeptin/Neurokinin B/Dynorphin (KNDy) Neurons Mediate the Estrogen Suppression of Gonadotropin Secretion and Body Weight
2012
Dynamics of gonadotropin-releasing hormone release during a pulse.
1992 Standout
NAFLD in Some Common Endocrine Diseases: Prevalence, Pathophysiology, and Principles of Diagnosis and Management
2019
Circadian Clock, Cancer, and Chemotherapy
2014 StandoutNobel
Characterization of the Physiological Pattern of Episodic Gonadotropin Secretion throughout the Human Menstrual Cycle*
1986
Hypogonadotropic Disorders in Men and Women: Diagnosis and Therapy with Pulsatile Gonadotropin-Releasing Hormone
1986
Regulation of gonadotropin, thyrotropin subunit, and prolactin messenger ribonucleic acid expression by pulsatile or continuous protein kinase-C stimulation.
1995
Insulin Resistance and the Polycystic Ovary Syndrome Revisited: An Update on Mechanisms and Implications
2012 Standout
The Oxytocin Receptor System: Structure, Function, and Regulation
2001 Standout
Fetal and Neonatal Exposure to the Endocrine Disruptor Methoxychlor Causes Epigenetic Alterations in Adult Ovarian Genes
2009
Functional Significance of Cell Volume Regulatory Mechanisms
1998 Standout
Sexual Differentiation of the Rodent Brain: Dogma and Beyond
2012
Evidence That 5-HT2AReceptors in the Hypothalamic Paraventricular Nucleus Mediate Neuroendocrine Responses to (−)DOI
2002
The Relationship between Maternal and Umbilical Cord Androgen Levels and Polycystic Ovary Syndrome in Adolescence: A Prospective Cohort Study
2009
Multimodal Influence of Estrogen upon Gonadotropin-Releasing Hormone Neurons
1998
GABA- and Glutamate-Activated Channels in Green Fluorescent Protein-Tagged Gonadotropin-Releasing Hormone Neurons in Transgenic Mice
1999
Hypocretin-1 Modulates Rapid Eye Movement Sleep through Activation of Locus Coeruleus Neurons
2000
An Increase in Kisspeptin-54 Release Occurs with the Pubertal Increase in Luteinizing Hormone-Releasing Hormone-1 Release in the Stalk-Median Eminence of Female Rhesus Monkeys in Vivo
2008
Xenoestrogen-Induced Regulation of EZH2 and Histone Methylation via Estrogen Receptor Signaling to PI3K/AKT
2010
Advances in Male Contraception
2008
Expression of c- fos Protein in Brain: Metabolic Mapping at the Cellular Level
1988 StandoutScience
Works of Jon E. Levine being referenced
Nonclassical estrogen receptor α signaling mediates negative feedback in the female mouse reproductive axis
2007
Timing and completion of puberty in female mice depend on estrogen receptor α-signaling in kisspeptin neurons
2010
Effects of Angiotensin II on LHRH Release, as Measured by in vivo Microdialysis of the Anterior Pituitary Gland of Conscious Female Rats
1992
Effects of experimental hyperandrogenemia on the female rat reproductive axis: Suppression of progesterone-receptor messenger RNA expression in the brain and blockade of luteinizing hormone surges
2005
Circadian Clock Mutation Disrupts Estrous Cyclicity and Maintenance of Pregnancy
2004
Vasopressin Regulation of the Proestrous Luteinizing Hormone Surge in Wild-Type and Clock Mutant Mice1
2006
Simultaneous Measurement of Luteinizing Hormone (LH)-Releasing Hormone, LH, and Follicle-Stimulating Hormone Release in Intact and Short-Term Castrate Rats*
1988
Neuropeptide Y potentiates luteinizing hormone (LH)-releasing hormone-induced LH secretion only under conditions leading to preovulatory LH surges.
1992
Acute administration of estrogen suppresses LH secretion without altering GnRH release in ovariectomized rhesus macaques
1990
Regulation of Kiss1 and Dynorphin Gene Expression in the Murine Brain by Classical and Nonclassical Estrogen Receptor Pathways
2009
Estrogen Inhibits Luteinizing Hormone (LH), but Not Follicle-Stimulating Hormone Secretion in Hypophysectomized Pituitary-Grafted Rats Receiving Pulsatile LH-Releasing Hormone Infusions*
1988
Microdialysis methods for in vivo neuropeptide measurement in the Stalk-median eminence in the Rhesus monkey
2007
Enhanced Sexual Behaviors and Androgen Receptor Immunoreactivity in the Male Progesterone Receptor Knockout Mouse
2005
Estrogen receptors in neuropeptide Y neurons: at the crossroads of feeding and reproduction
2006
Differential Gonadotropin Responses to N-Methyl-D,L-aspartate in Metestrous, Proestrous, and Ovariectomized Rats1
1993
Naloxone Stimulation of in vivo LHRH Release Is Not Diminished following Ovariectomy
1988
New insights into the classical and non-classical actions of estrogen: Evidence from estrogen receptor knock-out and knock-in mice
2008
Neuroendocrine Consequences of Prenatal Androgen Exposure in the Female Rat: Absence of Luteinizing Hormone Surges, Suppression of Progesterone Receptor Gene Expression, and Acceleration of the Gonadotropin-Releasing Hormone Pulse Generator1
2005
Neuropeptide Y Potentiates Luteinizing Hormone (LH)-Releasing Hormone-Stimulated LH Surges in Pentobarbital-Blocked Proestrous Rats*
1991
New Concepts of the Neuroendocrine Regulation of Gonadotropin Surges in Rats
1997
Differential Gonadotropin Responses to N-Methyl-D,L-aspartate in Intact and Castrated Male Rats1
1993
Endocrine Antecedents of Polycystic Ovary Syndrome in Fetal and Infant Prenatally Androgenized Female Rhesus Monkeys1
2008
Distribution of a Renin-Releasing Factor in the Central Nervous System of the Rat
1992
Neuroendocrine Regulation of the Luteinizing Hormone-Releasing Hormone Pulse Generator in the Rat
1991
Genetic rescue of nonclassical ERα signaling normalizes energy balance in obese Erα-null mutant mice
2011
Transient prenatal androgen exposure produces metabolic syndrome in adult female rats
2008
Neuroendocrine consequences of androgen excess in female rodents
2008
Neuropeptide Y stimulates luteinizing hormone-releasing hormone release from superfused hypothalamic GT1-7 cells.
1994
Stimulation of Gonadotropin-Releasing Hormone Surges by Estrogen. II. Role of Cyclic Adenosine 3′,5′-Monophosphate
2000
Nonhuman primate models of polycystic ovary syndrome
2013
Progesterone Receptors as Neuroendocrine Integrators
2001
Impaired Estrogen Feedback and Infertility in Female Mice with Pituitary-Specific Deletion of Estrogen Receptor Alpha (ESR1)1
2009
Estrogen Receptor α Signaling Pathways Differentially Regulate Gonadotropin Subunit Gene Expression and Serum Follicle-Stimulating Hormone in the Female Mouse
2008
Stimulation of Gonadotropin-Releasing Hormone Surges by Estrogen. I. Role of Hypothalamic Progesterone Receptors
2000
Hyperandrogenic origins of polycystic ovary syndrome – implications for pathophysiology and therapy
2019
Estrous cycle stage-dependent effects of neuropeptide-Y on luteinizing hormone (LH)-releasing hormone-stimulated LH and follicle-stimulating hormone secretion from anterior pituitary fragments in vitro.
1993
Luteinizing Hormone-Releasing Hormone Release during the Rat Estrous Cycle and after Ovariectomy, as Estimated with Push-Pull Cannulae*
1982
Serotonin in Hypothalamic Nuclei: Increased Content after Castration of Male Rats
1978
Pubertal Acceleration of Pulsatile Gonadotropin-Releasing Hormone Release in Male Rats as Revealed by Microdialysis
2002
Oocytes are a source of catecholamines in the primate ovary: Evidence for a cell–cell regulatory loop
1998
Acute increase in responsiveness of luteinizing hormone (LH)-releasing hormone nerve terminals to neuropeptide-Y stimulation before the preovulatory LH surge.
1994
In VitroGonadotropin-Releasing Hormone Release from Hypothalamic Tissues of Ovariectomized Estrogen-Treated Cynomolgus Macaques*
1985
Estrogen Response Element-Independent Estrogen Receptor (ER)-α Signaling Does Not Rescue Sexual Behavior but Restores Normal Testosterone Secretion in Male ERα Knockout Mice
2007
In VivoGonadotropin-Releasing Hormone Release and Serum Luteinizing Hormone Measurements in Ovariectomized, Estrogen-Treated Rhesus Macaques*
1985
Neuropeptide Y gene expression in the arcuate nucleus is increased during preovulatory luteinizing hormone surges.
1992
Rapid photoperiod-induced increase in detectable GnRH mRNA-containing cells in Siberian hamster
1997
In Vivo Release of Luteinizing Hormone-Releasing Hormone Estimated with Push-Pull Cannulae from the Mediobasal Hypothalami of Ovariectomized, Steroid- Primed Rats*
1980
Noradrenergic activity in rat brain during rapid eye movement sleep deprivation and rebound sleep
1995
RU486 administration blocks neuropeptide Y potentiation of luteinizing hormone (LH)-releasing hormone-induced LH surges in proestrous rats.
1993
Endocrine Defects in Mice Carrying a Null Mutation for the Progesterone Receptor Gene*
1997
In Vivo Gonadotropin-Releasing Hormone Secretion in Female Rats during Peripubertal Development and on Proestrus*
2001
Neuropeptide Y gene expression in the arcuate nucleus: sexual dimorphism and modulation by testosterone.
1993
Reproductive Abnormalities in Human IGF Binding Protein-1 Transgenic Female Mice
2002
Simultaneous Measurement of Luteinizing Hormone-Releasing Hormone and Luteinizing Hormone Release in Unanesthetized, Ovariectomized Sheep*
1982
Estrogen Induces Neuropeptide Y (NPY) Y1 Receptor Gene Expression and Responsiveness to NPY in Gonadotrope-Enriched Pituitary Cell Cultures
2004
Combined electrophysiological, immunocytochemical and peptide release measurements in the hypothalamic slice
1985