Standout Papers
Citation Impact
Citing Papers
Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 StandoutScienceNobel
Maturation-Dependent HIV-1 Surface Protein Redistribution Revealed by Fluorescence Nanoscopy
2012 StandoutScienceNobel
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Campylobacter gene polymorphism as a determinant of clinical features of Guillain–Barre syndrome
2005
Distinguishing acute-onset CIDP from fluctuating Guillain-Barre syndrome
2010
Uracil DNA Glycosylase Activity Is Dispensable for Immunoglobulin Class Switch
2004 StandoutScienceNobel
AID Enzyme-Induced Hypermutation in an Actively Transcribed Gene in Fibroblasts
2002 StandoutScienceNobel
The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency
2008 StandoutScienceNobel
Selection and Characterization of a Replication-Competent Human Immunodeficiency Virus Type 1 Variant Encoding C-Terminally Truncated Env
2006
Cutting Edge: CD40 Ligand Is Not Essential for the Development of Cell-Mediated Immunity and Resistance toMycobacterium tuberculosis
1998
Mycoplasma pneumoniae triggering the Guillain‐Barré syndrome: A case‐control study
2016
CD40 Ligand Exerts Differential Effects on the Expression of Iγ Transcripts in Subclones of an IgM+ Human B Cell Lymphoma Line
1998
Affinity Maturation in Lyn Kinase-Deficient Mice with Defective Germinal Center Formation
1998
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
Immune privilege of the CNS is not the consequence of limited antigen sampling
2014
Transcriptomic profiling of microglia and astrocytes throughout aging
2020
Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells
1995
Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade
2003
Psoriasis
2009 Standout
Mechanisms of transplant tolerance induction using costimulatory blockade
2002
Help for cytotoxic-T-cell responses is mediated by CD40 signalling
1998 StandoutNature
Follicular Dendritic Cells and Germinal Centers
1996
CD40 ligand-transduced co-stimulation of T cells in the development of helper function
1995 Nature
Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration
2018
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Microglial immune checkpoint mechanisms
2018
Guillain‐Barré Syndrome Animal Model: The First Proof of Molecular Mimicry in Human Autoimmune Disorder
2010
Carbohydrate mimicry: a new paradigm of autoimmune diseases
2005
Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity
2000
Reduction of atherosclerosis in mice by inhibition of CD40 signalling
1998 Nature
A ‘GAG’ reflex prevents repair of the damaged CNS
2007
Quantitative analysis of LP-BM5 murine leukemia retrovirus RNA using real-time RT-PCR
2003
Guillain-Barré syndrome
2016 Standout
CD40 signaling induces interleukin‐4‐independent IgE switching in vivo
1996
CD40 Ligand Is Required for Protective Cell-Mediated Immunity to Leishmania major
1996
Murine AIDS requires CD154/CD40L expression by the CD4 T cells that mediate retrovirus-induced disease: Is CD4 T cell receptor ligation needed?
2006
Evidence for a Continued Requirement for CD40/CD40 Ligand (CD154) Interactions in the Progression of LP-BM5 Retrovirus-Induced Murine AIDS
1998
The AID enzyme induces class switch recombination in fibroblasts
2002 StandoutNatureNobel
An anti‐ganglioside antibody‐secreting hybridoma induces neuropathy in mice
2004
Siglecs at the Host–Pathogen Interface
2020
What is immune privilege (not)?
2006
Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand
1995 Nature
Structural and functional features of central nervous system lymphatic vessels
2015 StandoutNature
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
2006
Overexpression of GD1a Ganglioside Sensitizes Motor Nerve Terminals to Anti-GD1a Antibody-Mediated Injury in a Model of Acute Motor Axonal Neuropathy
2005
Glycolipid antigens and autoantibodies in autoimmune neuropathies
2013
Defects of somatic hypermutation and class switching in alymphoplasia (aly) mutant mice
1996 StandoutNobel
Lymphatic drainage of the brain and the pathophysiology of neurological disease
2008
CD28 co-stimulation stabilizes the expression of the CD40 ligand on T cells
1998
PROLONGED SURVIVAL OF MOUSE SKIN ALLOGRAFTS IN RECIPIENTS TREATED WITH DONOR SPLENOCYTES AND ANTIBODY TO CD40 LIGAND1
1997
Type I Interferon in Systemic Lupus Erythematosus and Other Autoimmune Diseases
2006
Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates
1999 Standout
A Chimpanzee Genome Project Is a Biomedical Imperative: Figure B1.
2000
Taking dendritic cells into medicine
2007 StandoutNatureNobel
Human uracil–DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination
2003
A novel link between Campylobacter jejuni bacteriophage defence, virulence and Guillain–Barré syndrome
2012
In situ class switching and differentiation to IgA-producing cells in the gut lamina propria
2001 StandoutNatureNobel
Marginal Zone and B1 B Cells Unite in the Early Response against T-Independent Blood-Borne Particulate Antigens
2001
Axonal Guillain-Barré syndrome: concepts and controversies
2013
Atherosclerosis — An Inflammatory Disease
1999 Standout
Pathophysiological actions of neuropathy‐related anti‐ganglioside antibodies at the neuromuscular junction
2009
The CD40-TRAF6 axis controls affinity maturation and the generation of long-lived plasma cells
2002
Disruption of CD40–CD40 Ligand Interactions Results in an Enhanced Susceptibility to Leishmania amazonensis Infection
1996
Diagnosis, treatment and prognosis of Guillain-Barré syndrome (GBS)
2013
Mechanisms of distal axonal degeneration in peripheral neuropathies
2015
Peripheral neuropathies and anti-glycolipid antibodies
2002
Guillain–Barré syndrome: pathogenesis, diagnosis, treatment and prognosis
2014
ICOS is essential for effective T-helper-cell responses
2001 Nature
Anti-ganglioside complex antibodies associated with severe disability in GBS
2006
A central role of CD40 ligand in the regulation of CD4+ T-cell responses
1996
A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q
2006 StandoutNobel
The anatomical and cellular basis of immune surveillance in the central nervous system
2012
CD40-deficient mice infected with the defective murine leukemia virus LP-BM5def do not develop murine AIDS but produce IgE and IgG1in vivo
1999
The Biology of CRISPR-Cas: Backward and Forward
2018 StandoutNobel
Protective Role of CD40 in Leishmania major Infection at Two Distinct Phases of Cell-Mediated Immunity
1996
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
2000 StandoutNatureNobel
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Pathophysiology of the lymphatic drainage of the central nervous system: Implications for pathogenesis and therapy of multiple sclerosis
2009
The Pathobiology of Vascular Dementia
2013 Standout
Treatment of immune neuropathies
2002
CD40-gp39 INTERACTIONS PLAY A CRITICAL ROLE DURING ALLOGRAFT REJECTION
1996
Multiple sclerosis: a complicated picture of autoimmunity
2007
Critical Roles for the Bcl-3 Oncoprotein in T Cell–Mediated Immunity, Splenic Microarchitecture, and Germinal Center Reactions
1997
Selective Targeting of TNF Receptors as a Novel Therapeutic Approach
2020
Microglial Corpse Clearance: Lessons From Macrophages
2020
Guillain-Barré syndrome
2005 Standout
CD40-Associated TRAF 6 Signaling Is Required for Disease Induction in a Retrovirus-Induced Murine Immunodeficiency
2004
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Cross-reactive anti-galactocerebroside antibodies and Mycoplasma pneumoniae infections in Guillain–Barré syndrome
2002
The crucial role of Campylobacter jejuni genes in anti-ganglioside antibody induction in Guillain-Barré syndrome
2004
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Development of Virus-Like Particle Technology from Small Highly Symmetric to Large Complex Virus-Like Particle Structures
2013 Standout
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
CD40 Ligand Blockade Induces CD4+ T Cell Tolerance and Linked Suppression
1999
Mice Deficient in Nuclear Factor (NF)-κB/p52 Present with Defects in Humoral Responses, Germinal Center Reactions, and Splenic Microarchitecture
1998
TRANCE, a TNF Family Member, Is Differentially Expressed on T Cell Subsets and Induces Cytokine Production in Dendritic Cells
1999 StandoutNobel
The JNK Pathway Regulates the In Vivo Deletion of Immature CD4+CD8+ Thymocytes
1998
Establishment of NOD-Pdcd1-/-mice as an efficient animal model of type I diabetes
2005 StandoutNobel
CD40 ligand exerts differential effects on the expression of I gamma transcripts in subclones of an IgM+ human B cell lymphoma line.
1998
Memory B cell development but not germinal center formation is impaired by in vivo blockade of CD40-CD40 ligand interaction.
1994
Axonal variant of Guillain-Barre syndrome associated with Campylobacter infection in Bangladesh
2010
Hyperresponsive B Cells in CD22-Deficient Mice
1996 Science
T cells traffic from brain to cervical lymph nodes via the cribroid plate and the nasal mucosa
2006
Activation of NF-κB/Rel by CD40 Engagement Induces the Mouse Germ Line Immunoglobulin Cγ1 Promoter
1996
Localization of Splenic B Cells Activated for Switch Recombination by In Situ Hybridization with Iγ1 Switch Transcript and Rad51 Probes
1998
Genetics of Guillain‐Barré syndrome (GBS ) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP ): current knowledge and future directions
2014
The occurrence of Guillain-Barre syndrome within families
2004
CD40 Ligation on Human Cord Blood CD34+Hematopoietic Progenitors Induces Their Proliferation and Differentiation into Functional Dendritic Cells
1997
B7x: A widely expressed B7 family member that inhibits T cell activation
2003 StandoutNobel
A role for E2F1 in the induction of ARF, p53, and apoptosis during thymic negative selection.
1999
CD40-CD40 ligand interactions are critical in T-B cooperation but not for other anti-viral CD4+ T cell functions.
1996
Critical Roles of Activation-Induced Cytidine Deaminase in the Homeostasis of Gut Flora
2002 StandoutScienceNobel
Plasmacytoid predendritic cells initiate psoriasis through interferon-α production
2005
Localization of splenic B cells activated for switch recombination by in situ hybridization with Igamma1 switch transcript and Rad51 probes.
1998
Molecular Mechanism of Class Switch Recombination: Linkage with Somatic Hypermutation
2002 StandoutNobel
Carbohydrate mimicry between human ganglioside GM1 and Campylobacter jejuni lipooligosaccharide causes Guillain–Barré syndrome
2004
CD40 ligand is not essential for the development of cell-mediated immunity and resistance to Mycobacterium tuberculosis.
1998
Impaired Antibody Response to Group B Streptococcal Type III Capsular Polysaccharide in C3- and Complement Receptor 2-Deficient Mice
2003
Transplantation of human neural stem cells for spinal cord injury in primates
2005
Cytolytic CD8+ T Cells Directed against a Cryptic Epitope Derived from a Retroviral Alternative Reading Frame Confer Disease Protection
2006
Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut
2004 StandoutNobel
CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response.
1996
Pain in Guillain-Barré syndrome
2010
Increased T Cell Autoreactivity in the Absence of CD40-CD40 Ligand Interactions: A Role of CD40 in Regulatory T Cell Development
2001 StandoutNobel
Identification of a costimulatory molecule rapidly induced by CD40L as CD44H.
1996
Critical Roles of Pten in B Cell Homeostasis and Immunoglobulin Class Switch Recombination
2003 StandoutNobel
Lineage-Restricted Function of Nuclear Factor κB–Inducing Kinase (Nik) in Transducing Signals via Cd40
2000 StandoutNobel
Transient subversion of CD40 ligand function diminishes immune responses to adenovirus vectors in mouse liver and lung tissues
1996
IMMUNE REGULATION BY CD40 AND ITS LIGAND GP39
1996
Characterization of the CD154-Positive and CD40-Positive Cellular Subsets Required for Pathogenesis in Retrovirus-Induced Murine Immunodeficiency
2001
Antecedent infections in Fisher syndrome
2005
Infections and course of disease in mild forms of Guillain–Barre syndrome
2002
The Programmed Death-1 and Interleukin-10 Pathways Play a Down-Modulatory Role in LP-BM5 Retrovirus-Induced Murine Immunodeficiency Syndrome
2007 StandoutNobel
Intra- and Interspecific Variation in Primate Gene Expression Patterns
2002 StandoutScienceNobel
CD19 Signaling Pathways Play a Major Role for Murine AIDS Induction and Progression
2002
Possible Role of Interleukin-10 (IL-10) and CD40 Ligand Expression in the Pathogenesis of Hypergammaglobulinemia in Human Immunodeficiency Virus Infection: Modulation of IL-10 and Ig Production After Intravenous Ig Infusion
1998
Conditional stability of T cells
2010 StandoutNatureNobel
Involvement of CRAF1, a relative of TRAF, in CD40 signaling
1995 ScienceNobel
T-Independent Immune Response: New Aspects of B Cell Biology
2000 StandoutScienceNobel
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine
2001 StandoutNobel
Acute motor axonal neuropathy after Mycoplasma infection
2004
CD40 Ligand-Dependent T Cell Activation: Requirement of B7-CD28 Signaling Through CD40
1996 Science
In vitro complement-dependent binding and in vivo kinetics of pneumococcal polysaccharide TI-2 antigens in the rat spleen marginal zone and follicle
1996
CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosis.
1996
T Cell Accumulation in B Cell Follicles Is Regulated by Dendritic Cells and Is Independent of B Cell Activation
2003
Paraparetic Guillain-Barré syndrome
2014
The Role of CD4 T Cells in the Pathogenesis of Murine AIDS
2006
Immune and inflammatory responses in TNF alpha-deficient mice: a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response.
1996
The CD154/CD40 Interaction Required for Retrovirus-Induced Murine Immunodeficiency Syndrome Is Not Mediated by Upregulation of the CD80/CD86 Costimulatory Molecules
2002
CD40 AND CD154 IN CELL-MEDIATED IMMUNITY
1998
Possible Role of Interleukin-10 (IL-10) and CD40 Ligand Expression in the Pathogenesis of Hypergammaglobulinemia in Human Immunodeficiency Virus Infection: Modulation of IL-10 and Ig Production After Intravenous Ig Infusion
1998
The B7 Family of Ligands and Its Receptors: New Pathways for Costimulation and Inhibition of Immune Responses
2002
Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice
2011 StandoutNobel
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
Requirement for CD40 Ligand in Costimulation Induction, T Cell Activation, and Experimental Allergic Encephalomyelitis
1996 Science
CD4+ T Cell Responses to CD40-Deficient APCs: Defects in Proliferation and Negative Selection Apply Only with B Cells as APCs
1999
Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand.
1995
Expression of a Functional Eotaxin (CC Chemokine Ligand 11) Receptor CCR3 by Human Dendritic Cells
2002 StandoutNobel
Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells.
1996
Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration
2000 StandoutScienceNobel
Immunological Memory and Protective Immunity: Understanding Their Relation
1996 StandoutScience
CD40 ligand-deficient mice generate a normal primary cytotoxic T-lymphocyte response but a defective humoral response to a viral infection
1996
Analysis of the Underlying Cellular Mechanisms of Anti-CD154-Induced Graft Tolerance: The Interplay of Clonal Anergy and Immune Regulation
2005 StandoutNobel
Characterization of CD40‐Dependent Immunoglobulin Class Switching
1999
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
2002 StandoutNobel
Differentiation of Langerhans cells in Langerhans cell histiocytosis
2001
Hyper Immunoglobulin E Response in Mice with Monoclonal Populations of B and T Lymphocytes✪
2001
Nuclear Factor (NF)-κB2 (p100/p52) Is Required for Normal Splenic Microarchitecture and B Cell–mediated Immune Responses
1998
Works of Jon D. Laman being referenced
Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis
2009 Standout
Complement‐mediated follicular localization of T‐independent type‐2 antigens: the role of marginal zone macrophages revisited
1992
Functional polymorphisms in LPS receptors CD14 and TLR4 are not associated with disease susceptibility or Campylobacter jejuni infection in Guillain–Barré patients
2004
Transcriptomic analysis of purified human cortical microglia reveals age-associated changes
2017
In Psoriasis Lesional Skin the Type I Interferon Signaling Pathway Is Activated, Whereas Interferon-α Sensitivity Is Unaltered
2004
Campylobacter jejuni lipopolysaccharides from Guillain–Barré syndrome patients induce IgG anti-GM1 antibodies in rabbits
2000
Functions of CD40 and Its Ligand, gp39 (CD40L)
2017
Genetic polymorphisms of macrophage-mediators in Guillain–Barré syndrome
2007
In vivo T-B cell interactions and cytokine-production in the spleen
1994
Drainage of Cells and Soluble Antigen from the CNS to Regional Lymph Nodes
2013
In vivo detection of myelin proteins in cervical lymph nodes of MS patients using ultrasound-guided fine-needle aspiration cytology
2005
Selective Modulation of TNF–TNFRs Signaling: Insights for Multiple Sclerosis Treatment
2018
A new primate model for multiple sclerosis in the common marmoset
2000
Surgical excision of CNS‐draining lymph nodes reduces relapse severity in chronic‐relapsing experimental autoimmune encephalomyelitis
2008
Functions of CD40 and Its Ligand, gp39 (CD40L)
1996
Epitope Mapping and Topology of Baculovirus-Expressed HIV-1 gp160 Determined with a Panel of Murine Monoclonal Antibodies
1994
Characteristics of primary infection of a European human immunodeficiency virus type 1 clade B isolate in chimpanzees.
1998
Immunodeficiency due to a faulty interaction between T cells and B cells
1994
Fas polymorphisms are associated with the presence of anti-ganglioside antibodies in Guillain–Barré syndrome
2005
Modelling of multiple sclerosis: lessons learned in a non-human primate
2004
CD11c-expressing cells reside in the juxtavascular parenchyma and extend processes into the glia limitans of the mouse nervous system
2010
Mice deficient for the CD40 ligand
1994
Tolerogenic effect of fiber tract injury: reduced EAE severity following entorhinal cortex lesion
2006
Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis.
1995
Innate I mmunity to C ampylobacter jejuni in G uillain‐B arré S yndrome
2015
Mannose-Binding Lectin Contributes to the Severity of Guillain-Barre Syndrome
2006
Cross-reactive antibodies against GM2 and CMV-infected fibroblasts in Guillain–Barre syndrome
2000
An essential role for gp39, the ligand for CD40, in thymic selection.
1995
Structure ofCampylobacter jejuniLipopolysaccharides Determines Antiganglioside Specificity and Clinical Features of Guillain-Barre and Miller Fisher Patients
2002
Sialylation of Campylobacter jejuni Endotoxin Promotes Dendritic Cell–Mediated B Cell Responses through CD14-Dependent Production of IFN-β and TNF-α
2013
Prevention of Experimental Autoimmune Encephalomyelitis in Common Marmosets Using an Anti-IL-12p40 Monoclonal Antibody
2002
Differential In situ cytokine profiles of Langerhans-like cells and T cells in Langerhans cell histiocytosis: abundant expression of cytokines relevant to disease and treatment.
1999
Guillain-Barre Syndrome- and Miller Fisher Syndrome-Associated Campylobacter jejuni Lipopolysaccharides Induce Anti-GM 1 and Anti-GQ 1b Antibodies in Rabbits
2001
gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory.
1994
Transfer of Central Nervous System Autoantigens and Presentation in Secondary Lymphoid Organs
2002
Antibody to the ligand for CD40 (gp39) inhibits murine AIDS-associated splenomegaly, hypergammaglobulinemia, and immunodeficiency in disease-susceptible C57BL/6 mice
1996
Therapy with antibodies against CD40L (CD154) and CD44-variant isoforms reduces experimental autoimmune encephalomyelitis induced by a proteolipid protein peptide
1998
The Guillain–Barré syndrome: a true case of molecular mimicry
2003
Variant-specific monoclonal and group-specific polyclonal human immunodeficiency virus type 1 neutralizing antibodies raised with synthetic peptides from the gp120 third variable domain
1992
HLA class II alleles are not a general susceptibility factor in Guillain–Barre syndrome
2005
Ganglioside Mimicry ofCampylobacter jejuniLipopolysaccharides Determines Antiganglioside Specificity in Rabbits
2002